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| 1 | Aspartate transaminase to platelet ratio index in hepatitis C virus and Schistosomiasis coinfection显示文摘AIM: To assess the diagnostic accuracy,of aminotransferase-to-platelet ratio index(APRI) alone and with antischistosomal antibody(Ab) in patients with hepatitis C virus(HCV) and schistosomiasis coinfection. METHODS: This retrospective study included medical records of three hundred and eighty three Egyptianmen patients who had undergone percutaneous liver biopsy between January 2006 to April 2014 in tertiary care hospital in Qatar for diagnosis or monitoring purpose were selected. Data of patients > 18 years of age were included in the study. The values of HCV RNA titer and antischistosomal antibody titer were also taken into consideration. Patients were excluded from the study if they had any other concomitant chronic liver disease,including; history of previous antiviral or interferon therapy,immunosuppressive,therapy,chronic hepatitis B infection,human immunodeficiency virus co-infection,autoimmune hepatitis,decompensated liver disease,hepatocellular carcinoma,prior liver transplantation,and if no data about the liver biopsy present. RESULTS: Median age of patients was 46 years. About 7.1% had no fibrosis,whereas 30.4%,37.5%,20.4%,and 4.6% had fibrosis of stage Ⅰ,Ⅱ,Ⅲ,and Ⅳ respectively. In bivariate analysis,APRI score,levels of AST,platelet count and age of patient showed statistically significant association with liver fibrosis(P < 0.0001); whereas antischistosomal antibody titer(P = 0.52) and HCV RNA titer(P = 0.79) failed to show a significant association. The respective AUC values for no fibrosis,significant fibrosis,severe fibrosis and cirrhosis of APRI score were 63%,73.2%,81.1% and 88.9% respectively. This showed good sensitivity and specificity of APRI alone for grading of liver fibrosis. But the inclusion of anti-Schistosoma antibody did not improve the prediction of fibrosis stage. CONCLUSION: The study results suggest that noninvasive biochemical markers like APRI are sensitive and specific in diagnosing the degree of fibrosis and cirrhosis in patients with coinfection of HCV and schistosomiasis as compared to biopsy. The addition of antischistosomal Ab to APRI did not improve sensitivity for predicting the degree of cirrhosis. | Moutaz Derbala Mohammed Elshiekh Elbadri Aliaa Mohamed Amer Saad Al Kaabi Khaleel Hassan Sultan Yasser Medhat Kamel Eman Hassan Satti Elsayed Tony Yervant Avades Prem Chandra Fatma M Shebl | 2015 | World Journal of Gastroenterology2015，21，46： | 2 |
| 2 | Friction and wear of copper-graphite composites made with Cu-coated and uncoated graphite powders 显示文摘 | MOUSTAFA S F ELBADRY S A SANAD A M | 2002 | Wear2002，253，78： | 1 |
| 3 | Temperature Variations in Concrete Bridges 显示文摘 | ELBADRY M M GHALI A | 1983 | Journal of Structual Engineeing ASCE1983，109，10： | 1 |
| 4 | Temperature variations in concrete bridges 显示文摘 | Elbadry M Ghali A | 1993 | Journal of Structural Engineering ASCE1993，109，10： | 1 |
| 5 | Temperature variations in concrete bridges显示文摘 | Elbadry M M Ghail A | | 0，，10： | 1 |
| 6 | Mo1016 Prospective Randomized Controlled Study of Radiofrequency Ablation and Partial Splenic Embolization in the Treatment of Hypersplenism in Patients With Post-Hepatitis C Cirrhosis显示文摘 | Wasfy E S A Elbadry A Abdel Baset M H | 2014 | Gastroenterology2014，5，146： | 1 |
| 7 | Temperature variations in concrete bridges显示文摘 | Elbadry M M Ghali A | 1983 | Journal of Structural Engineering1983，109，10： | 1 |
| 8 | Morphological differ- ences among Radopholus similis (Cobb, 1893) Thorne, 1949 populations显示文摘 | Elbadri G A A Geraert E Moens M | 1999 | Russian Journal of Nematode1999，7，2： | 1 |
| 9 | Temperature variations in concrete bridges显示文摘 | ELBADRY M M GHAIL A | 1983 | Journal of the Structural Engineering ASCE1983，109，10： | 1 |
| 10 | Temperature variations in con- crete bridges 显示文摘 | Elbadry M M Ghall A | 1983 | Journal of Structural Engineering ASCE1983，109，10： | 1 |
| 11 | Control of Thermal Cracking of Concrete Structures显示文摘 | Elbadry M Ghali A | 1995 | AC1 Journal1995，，7： | 1 |
| 12 | Temperature Variation in Concrete Bridges显示文摘 | Elbadry M Ghalli A | 1983 | Journal of Structural Engineering ASCE1983，109，10： | 1 |
| 13 | Temperature variations in concrete bridges 显示文摘 | Elbadry M Ghali A | 1983 | Journal of Structural Engineering ASCE1983，109，10： | 1 |
| 14 | Temperature variations in concrete bridges显示文摘 | ELBADRY M M GHALI A | 1983 | Journal of Structural Engineering ASCE1983，109，10： | 1 |
| 15 | Temperature Variations in Concrete Bridges显示文摘 | Elbadry M M Ghail A | 1983 | Journal of the Structural Engineering1983，109，10： | 1 |
| 16 | Temperature variations in concrete bridges显示文摘 | Elbadry M M Ghali A | | 0，，10： | 1 |
| 17 | Temperature variations in concrete bridges显示文摘 | Elbadry M M Ghail A | 1983 | Journal of the Structural Engineering1983，109，10： | 1 |
| 18 | Temperature Variations in Con- crete Bridge 显示文摘 | ELBADRY M GHALI A | 1983 | Journal of Structure Engineering ASCE1983，109，10： | 1 |
| 19 | Temperature variations in concretebridges 显示文摘 | Elbadry M Ghali A | 1983 | Journal of Structural Engineering A S C E1983，109，10： | 1 |
| 20 | Temperature variations in concrete bridges 显示文摘 | Elbadry M M Ghali A | 1983 | Journal of Structural Engineer- ing1983，109，10： | 1 |
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