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| 1 | Changes in nitrogen budget and potential risk to the environment over 20 years(1990–2010) in the agroecosystems of the Haihe Basin, China显示文摘The nitrogen balance can serve as an indicator of the risk to the environment of nitrogen loss from agricultural land. To investigate the temporal and spatial changes in agricultural nitrogen application and its potential threat to the environment of the Haihe Basin in China, we used a database of county-level agricultural statistics to calculate agricultural nitrogen input, output,surplus intensity, and use efficiency. Chemical fertilizer nitrogen input increased by 51.7% from1990 to 2000 and by 37.2% from 2000 to 2010, concomitant with increasing crop yields.Simultaneously, the nitrogen surplus intensity increased by 53.5% from 1990 to 2000 and by16.5% from 2000 to 2010, presenting a continuously increased environmental risk. Nitrogen use efficiency decreased from 0.46 in 1990 to 0.42 in 2000 and remained constant at 0.42 in 2010,partly due to fertilizer composition and type improvement. This level indicates that more than half of nitrogen inputs are lost in agroecosystems. Our results suggest that although the improvement in fertilizer composition and types has partially offset the decrease in nitrogen use efficiency, the environmental risk has still increased gradually over the past 20 years, along with the increase in crop yields and nitrogen application. It is important to achieve a better nitrogen balance through more effective management to significantly reduce the environmental risk,decrease nitrogen surplus intensity, and increase nitrogen use efficiency without sacrificing crop yields. | Mengmeng Zheng Hua Zheng Yingxia Wu Yi Xiao Yihua Du Weihua Xu Fei Lu Xiaoke Wang Zhiyun Ouyang | 2015 | Journal of Environmental Sciences2015，27，2： | 6 |
| 2 | Immunological and metabolic characteristics of the Omicron variants infection显示文摘The Omicron variants of SARS-CoV-2,primarily authenticated in November 2021 in South Africa,has initiated the 5th wave of global pandemics.Here,we systemically examined immunological and metabolic characteristics of Omicron variants infection.We found Omicron resisted to neutralizing antibody targeting receptor binding domain(RBD)of wildtype SARS-CoV-2.Omicron could hardly be neutralized by sera of Corona Virus Disease 2019(COVID-19)convalescents infected with the Delta variant.Through mass spectrometry on MHC-bound peptidomes,we found that the spike protein of the Omicron variants could generate additional CD8+T cell epitopes,compared with Delta.These epitopes could induce robust CD8+T cell responses.Moreover,we found booster vaccination increased the cross-memory CD8+T cell responses against Omicron.Metabolic regulome analysis of Omicron-specific T cell showed a metabolic profile that promoted the response of memory T cells.Consistently,a greater fraction of memory CD8+T cells existed in Omicron stimulated peripheral blood mononuclear cells(PBMCs).In addition,CD147 was also a receptor for the Omicron variants,and CD147 antibody inhibited infection of Omicron.CD147-mediated Omicron infection in a human CD147 transgenic mouse model induced exudative alveolar pneumonia.Taken together,our data suggested that vaccination booster and receptor blocking antibody are two effective strategies against Omicron. | Jiejie Geng Xu Yang Kun Wang Ke Wang Ruo Chen Zhi-Nan Chen Chuan Qin Guizhen Wu Youchun Wang Ke Xu Peng Du Jiangning Liu Shirui Chen Tao Zhang Xiuxuan Sun Ting Guo Ying Shi Zheng Zhang Ding Wei Peng Lin Qingyi Wang Jing Yuan Jiuxin Qu Jin Zou Yingxia Liu Hongzhou Lu Ping Zhu Huijie Bian Liang Chen | 2023 | Signal Transduction and Targeted Therapy2023，8，2： | 0 |
| 3 | Atmosphere CO2 increased concentration against lush membrane sponge stay显示文摘under lab conditions , studied the atmosphere CO2 effect of elevated concentrations on the filtration function of the lowest-equal multicellular animal sponge . in mock atmosphere CO2 Elevated concentrations of ecosystems , review CO2 concentration for 387, 750, 1000 mg/l under the environment , Lush film Sponge Hymeniacidonperlevis Stop sterilization of total organic carbon in seawater ( TOC) Capabilities . results show : in impersonation CO 2 concentration is 387 , 750, 1000 mg/l under the condition of Lush film sponge in H Clear seawater inside TOC The efficiency of IS 8%,67.6%, 50.0% and 15.4%, in the 24h to TOC The average drag retention rate for is (1.90±0.20 ,( 2.13±0.06 ,( 1.69±0.08 ,( 0.43± 0.11 mgkh-g Sponge ), The average purge rate is ( 0.025±0.002 ,( 0.033±0.001 ,( 0.019±0.001 ,( 0.004±0.001 mlkh.g sponge ), See Atmospher CO2 concentration from approximately 387 mg/l elevated to mg/l ,promotes lush film sponges prevent seawate from being in the sea TOC Ability , When the concentration is elevated to 750 mg/l suppresses the lush membrane sponge to stay TOC Capabilities , When the concentration is further elevation to 1000 mg/l , The causes the lush membrane sponge to almost lose its resistance to the seawater.TOC Capabilities . This study can be used for atmospheric 一: concentration The elevation of the effect of the sponge filtration function of intertidal zone and its possible ecological problems in nearshore waters . | Xu Hui Liu Hongwen Anzongfo Sheng Yu Line Du Yingxia | 2018 | Journal of Atmosphere and Oceanography Environment2018，6，1： | 0 |
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