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79篇 您的检索式:作者名="Du XM"
    题名 作者 年代 出处 被引量
1脊髓中TRPV4依赖的神经免疫轴促进神经病理性疼痛显示文摘小胶质细胞是中枢神经系统(central nervous system, CNS)的驻留巨噬细胞,对大脑的发育和稳态至关重要,并参与疾病发生。小胶质细胞的活化和增殖是包含神经病理性疼痛在内的诸多中枢神经系统疾病的标志。然而,在神经病理性疼痛中控制脊髓神经免疫轴的分子机制仍不完全清楚。该研究发现,基因敲除或药物阻断瞬时感受器电位香草素受体4 (transient receptor potential vanilloid 4, TRPV4)可显著减轻坐骨神经分支选择性损伤模型小鼠的神经病理性疼痛样行为。在机制上,小胶质细胞表达的TRPV4介导小胶质活化和增殖,并促进脂质运载蛋白2 (lipocalin-2)释放,增加脊髓兴奋性神经元的可塑性。该研究揭示,小胶质细胞的TRPV4通道处于脊髓神经免疫轴中心,将周围神经损伤转化为中枢敏化和神经病理性疼痛,进而将TRPV4确定为治疗慢性疼痛的潜在新靶点。沈周阳(译) 唐宗湘(校) Hu XM Du LX Liu SB 2023中国疼痛医学杂志2023,29,11:1
2Age-dependent cardiomy- opathy and heart failure phenotype in mice overexpressing 132-adrenergic receptors in the heart显示文摘Du XJ Gao XM Wang B 2000Cardiovasc Res2000,48,3:1
3Continuous blood purifica- tion ameliorates RhoA- mediated endothelial permeahilily in se- vere acJte pancreatitis patients with lung injury显示文摘DU XG CHEN XM GAN H 2011Int J Artif Organs2011,34,4:1
4Caspase-3 antisense oligodeoxynucleotides inhibit apoptosis in gammairradiated human leukemia HL-60 cells 显示文摘Zhang XT Song TB Du BL Li DM Li XM 2007Apoptosis2007,12,4:1
5Increased myocardial collagen and ventricular diastolic dysfunction in relaxin de- ficient mice: a gender-specific phenotype显示文摘Du XJ Samuel CS Gao XM 2003Cardiovasc Res2003,57,2:1
6Increased myocardial collagen and ventricular diastolic dysfunction in relaxin deficient mice:A gender-specific phenotype显示文摘Du XJ Samuel CS Gao XM 2003Cardiovasc Res2003,57,:1
7MicroRNA--182 regulates otocyst--derived cell differentiation and targets T--boxl gene 显示文摘Wang XR Zhang XM Du J 2012Hear Res2012,286,:1
8Genetic enhancement of ventricular contractility protects against pressure-overload-induced cardiac dysfunction 显示文摘Du XJ Lin F Gao XM 2004J Mol Cell Cardiol2004,37,5:1
9Granulocyte colony-stim- ulating factor increases the therapeutic efficacy of bone marrow mononuclear cell transplantation in cerebral ische- mia in miee显示文摘Zhang XM Du F Yang D 2011BMC Neurosci2011,12,:1
10HDL particle size is a crit- ical determinant of ABCAl-mediated macrophage cellular cholesterol export 显示文摘Du XM Kim M J Hou L 2015Circ Res2015,116,:1
11Continuous blood purificationameliorates RhoA-mediated endothelial permeability insevere acute pancreatitis patients with lung injury显示文摘Du XG Chen XM Gan H 2011Int J ArtifOrgans2011,34,4:1
12Crystal structure of HAbl 8G/CD147 : implications for immu- noglobulin superfamily homophilic adhesion 显示文摘YU XL HU T DU JM DING JP YANG XM ZHANG J 2008J Biol Chem2008,283,18:1
13Using ion-pair reversed-phase HPLC ICP-MS to simultaneously de- termine Cr (111) and Cr (VI) in urine of chromate workers显示文摘Wang HJ Du XM Wang M 2010Talanta2010,81,45:1
14MicroRNA-182 regulates otocyst-derived cell differentiation and targets T-boxl gene 显示文摘Wang XR Zhang XM Du J 2012Hear Res2012,286,55:1
15Hyperthermia conditioned astrocytecultured medium protects neurons from ischemic injury by the upregulation of HIF-1 alpha and the increased anti-apoptotic ability显示文摘Du F Wu XM Gong Q 2011Eur J Pharmacol2011,666,13:1
16Higher yielding isolation of kinsenoside in Anoectochilus and its antihyperliposis effect显示文摘Du XM Sun NY Tamura T 2001Biol Pharm Bull2001,24,1:1
17Increased myocardial collagen and ventricular diastolic dysfunction in relaxin deficient mice: a gender-specific phenotype 显示文摘Du XJ Samuel CS Gao XM 2003Cardiovasc Res2003,57,2:1
18Butanoic acid glucoside composition of whole body and in vitro plantlets of Anoectochilus formosanus显示文摘Du XM Yoshizawa T Shoyama Y 1998Phytochemistry1998,49,7:1
19Continuous blood purification amel-iorates RhoA -mediated endothelial permeability in severe acute pancrea-titis patients with lung injury显示文摘Du XG Chen XM Gan H et a1 0,,04:1
20Hepatoprotective aliphatic glycosides from three Goodyera species显示文摘Du XM Sun NY Chen Y 2000Biol Pharm Bull2000,23,6:1
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