|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 一种新的生物质热分解失重动力学模型显示文摘基于对8种中国生物质材料非等温热分解的实验结果,建立了描述生物质热解失重过程的“双组分分阶段反应模型”,这种模型相对于通常使用的“单组分全局反应模型”和“多组分全局反应模型’来说具有相当大的优点.利用积分型方法进行动力学分析表明,“双组分分阶段一级反应模型”适用于描述空气气氛下升温速率较低(如10℃/min)时生物质材料的树干和树叶试样的热分解失重动力学. | 刘乃安 范维澄 Dobashi Ritsu 林其钊 | 2001 | 科学通报2001，46，10： | 21 |
| 2 | Simplified criteria for diagnosing superficial esophageal squamous neoplasms using Narrow Band Imaging magnifying endoscopy显示文摘AIM To simplify the diagnostic criteria for superficial esophageal squamous cell carcinoma(SESCC) on Narrow Band Imaging combined with magnifying endoscopy(NBI-ME).METHODS This study was based on the post-hoc analysis of a randomized controlled trial. We performed NBI-ME for 147 patients with present or a history of squamous cell carcinoma in the head and neck, or esophagus between January 2009 and June 2011. Two expert endoscopistsdetected 89 lesions that were suspicious for SESCC lesions, which had been prospectively evaluated for the following 6 NBI-ME findings in real time: 'intervascular background coloration'; 'proliferation of intrapapillary capillary loops(IPCL)'; and 'dilation', 'tortuosity', 'change in caliber', and 'various shapes(VS)' of IPCLs(i.e., Inoue's tetrad criteria). The histologic examination of specimens was defined as the gold standard for diagnosis. A stepwise logistic regression analysis was used to identify candidates for the simplified criteria from among the 6 NBI-ME findings for diagnosing SESCCs. We evaluated diagnostic performance of the simplified criteria compared with that of Inoue's criteria.RESULTS Fifty-four lesions(65%) were histologically diagnosed as SESCCs and the others as low-grade intraepithelial neoplasia or inflammation. In the univariate analysis, proliferation, tortuosity, change in caliber, and VS were significantly associated with SESCC(P < 0.01). The combination of VS and proliferation was statistically extracted from the 6 NBI-ME findings by using the stepwise logistic regression model. We defined the combination of VS and proliferation as simplified dyad criteria for SESCC. The areas under the curve of the simplified dyad criteria and Inoue's tetrad criteria were 0.70 and 0.73, respectively. No significant difference was shown between them. The sensitivity, specificity, and accuracy of diagnosis for SESCC were 77.8%, 57.1%, 69.7% and 51.9%, 80.0%, 62.9% for the simplified dyad criteria and Inoue's tetrad criteria, respectively.CONCLUSION The combination of proliferation and VS may serve as simplified criteria for the diagnosis of SESCC using NBIME. | Akira Dobashi Kenichi Goda Noboru Yoshimura Tomohiko R Ohya Masayuki Kato Kazuki Sumiyama Masato Matsushima Shinichi Hirooka Masahiro Ikegami Hisao Tajiri | 2016 | World Journal of Gastroenterology2016，22，41： | 10 |
| 3 | Paraneoplastic syndromes associated with lung cancer显示文摘Paraneoplastic syndromes are signs or symptoms that occur as a result of organ or tissue damage at locations remote from the site of the primary tumor or metastases. Paraneoplastic syndromes associated with lung cancer can impair various organ functions and include neurologic, endocrine, dermatologic, rheumatologic, hematologic, and ophthalmological syndromes, as well as glomerulopathy and coagulopathy(Trousseau's syndrome). The histological type of lung cancer is generally dependent on the associated syndrome, the two most common of which are humoral hypercalcemia of malignancy in squamous cell carcinoma and the syndrome of inappropriate antidiuretic hormone secretion in small cell lung cancer. The symptoms often precede the diagnosis of the associated lung cancer, especially when the symptoms are neurologic or dermatologic. The proposed mechanisms of paraneoplastic processes include the aberrant release of humoral mediators, such as hormones and hormone-like peptides, cyto-kines, and antibodies. Treating the underlying cancer is generally the most effective therapy for paraneoplastic syndromes, and treatment soon after symptom onset appears to offer the best potential for symptom improvement. In this article, we review the diagnosis, potential mechanisms, and treatments of a wide variety of paraneoplastic syndromes associated with lung cancer. | Nobuhiro Kanaji Naoki Watanabe Nobuyuki Kita Shuji Bandoh Akira Tadokoro Tomoya Ishii Hiroaki Dobashi Takuya Matsunaga | 2014 | World Journal of Clinical Oncology2014，5，3： | 10 |
| 4 | Short-and long-term outcomes of endoscopically treated superficial non-ampullary duodenal epithelial tumors显示文摘BACKGROUND It is widely recognized that endoscopic resection(ER) of superficial nonampullary duodenal epithelial tumors(SNADETs) is technically challenging and may carry high risks of intraoperative and delayed bleeding and perforation.These adverse events could be more critical than those occurring in other levels of the gastrointestinal tract. Because of the low prevalence of the disease and the high risks of severe adverse events, the curability including short-and long-term outcomes have not been standardized yet.AIM To investigate the curability including short-and long-term outcomes of ER for SNADETs in a large case series.METHODS This retrospective study included cases that underwent ER for SNADETs at our university hospital between March 2004 and July 2017. Short-term outcomes of ER were measured based on en bloc and R0 resection rates as well as adverse events. Long-term outcomes included local recurrence detected on endoscopic surveillance and disease-specific mortality in patients followed up for ≥ 12 mo after ER.RESULTS In the study, 131 patients with 147 SNADETs were analyzed. The 147 ERs consisted of 136 endoscopic mucosal resections(EMRs)(93%) and 11 endoscopic submucosal dissections(ESDs)(7%). The median tumor diameter was 10 mm.The pathology diagnosis was adenocarcinoma(56/147, 38%), high-grade intraepithelial neoplasia(44/147, 30%), or low-grade intraepithelial neoplasia(47/147, 32%). The R0 resection rate was 68%(93/136) in the EMR group and73%(8/11) in the ESD group, respectively. Cap-assisted EMR(known as EMR-C)showed a higher rate of R0 resection compared to the conventional method of EMR using a snare(78% vs 62%, P = 0.06). No adverse event was observed in the EMR group, whereas delayed bleeding, intraoperative perforation, and delayed perforation in 3, 3, and 5 patients occurred in the ESD group, respectively. One patient with perforation required emergency surgery. In the 43 mo median follow-up period, local recurrence was found in four EMR cases and all cases were treated endoscopically. No patient died due to tumor recurrence.CONCLUSION Our findings suggest that ER provides good long-term outcomes in the patients with SNADETs. EMR is likely to become the safe and reliable treatment for small SNADETs. | Yuko Hara Kenichi Goda Akira Dobashi Tomohiko Richard Ohya Masayuki Kato Kazuki Sumiyama Takehiro Mitsuishi Shinichi Hirooka Masahiro Ikegami Hisao Tajiri | 2019 | World Journal of Gastroenterology2019，25，6： | 9 |
| 5 | An interactive rendering system using hierarchical data structure for earth-scale clouds显示文摘This paper presents an interactive system for realistic visualization of earth-scale clouds. Realistic images can be generated at interactive frame rates while the viewpoint and the sunlight directions can be changed interactively. The realistic display of earth-scale clouds requires us to render large volume data representing the density distribution of the clouds. However, this is generally time-consuming and it is difficult to achieve the interactive performance, especially when the sunlight direction can be changed. To address this, our system precomputes the integrated intensities and opacities of clouds for various viewing and sunlight directions. This idea is combined with a novel hierarchical data structure for further acceleration. The photorealism of the final image is improved by taking into account the atmospheric effects and shadows of clouds on the earth. We demonstrate the usefulness of our system by an application to a space flight simulation. | DOBASHI Yoshinori YAMAMOTO Tsuyoshi NISHITA Tomoyuki | 2010 | Science China(Information Sciences)2010，53，5： | 3 |
| 6 | Erythropoietin gene transfer into rat testes by in vivo electropo-ration may reduce the risk of germ cell loss caused by cryptorchidism显示文摘瞄准:由借助于在活体内 electroporation 把老鼠 Epo 基因变成地窟兰花睾丸在精子发生上调查老鼠红细胞生成素(Epo ) 的效果。方法:有通过手术导致的单方的隐睾病的 Sprague-Dawley 老鼠被划分成三个组:第一个组被给 pCAGGS-Epo (pCAGGS-Epo 组) 的睾丸内注射,第二个组被给 pCAGGS (pCAGGS 组) 的睾丸内注射,并且第三个组是给定的睾丸内注射缓冲磷酸盐 saline (PBS 组) 。同时, 30 V 的方形的电的脉搏与 100 ms 的一个时间常数被使用六次。在注射以后的一或二个星期,每个睾丸被称,总数的比率生殖细胞数到 Sertoli 房间(G/S 比率) 的被计算评估精子发生的缺陷。从每三个组拿的十个睾丸被检验在每次指。结果:在 pCAGGS-Epo 或 pCAGGS 控制原生质标志的注射以后的阴囊的重量是(0.85+/-0.08 ) g 并且(0.83+/-0.03 ) g,分别地在星期 1 点(P = 0.788 ) 并且(0.62+/-0.06 ) g 并且(0.52+/-0.02 ) g,分别地在星期 2 点(P = 0.047 ) 。在星期 1 点, spermatids 和精子比在控制睾丸的那些更充满有 pCAGGS-Epo 的睾丸。在星期 2 点, spermatids 和精子几乎没在任何一个组被检测。G/S 比率在星期 1 点是 23.27 +/-6.80 对 18.63+/-5.30 (P = 0.0078 ) 并且在星期 2 点的 7.16+/-3.06 对 6.05+/-1.58 (P = 0.1471 ) 分别地。结论:到由在活体内 electroporation 的老鼠睾丸的 Epo 的转移可以减少隐睾病引起的细菌房间损失的风险。 | Masaki Dobashi Kazumasa Goda Hiroki Maruyama Masato Fujisawa | 2005 | Asian Journal of Andrology2005，7，4： | 3 |
| 7 | Visual simulation of clouds显示文摘Clouds play an important role when synthesizing realistic images of outdoor scenes.The realistic display of clouds is therefore one of the important research topics in computer graphics.In order to display realistic clouds,we need methods for modeling,rendering,and animating clouds realistically.It is also important to control the shapes and appearances of clouds to create certain visual effects.In this paper,we explain our efforts and research results to meet such requirements,together with related researches on the visual simulation of clouds. | Yoshinori Dobashi Kei Iwasaki Yonghao Yue Tomoyuki Nishita | 2017 | Visual Informatics2017，1，1： | 2 |
| 8 | Experimental study on gas explosion behavior in enclo- sure 显示文摘 | Dobashi R | 1997 | Journal of Loss Prevention in the Process Industries1997，10，2： | 1 |
| 9 | Induction of apoptosis by ubenimes in human non - small - cell lung cancer lines显示文摘 | Ezawa K Minato K Dobashi K | 1996 | Biomed Pharmacother1996，50，： | 1 |
| 10 | Effect of beta-agonists on production of cytokines by activated T cells obtained from asthmatic patients and normal subjects显示文摘 | Aihara M Dobashi K Horie T | 1999 | J Asthma1999，36，7： | 1 |
| 11 | Skylight for interior lighting design显示文摘 | Dobashi Y Kaneda K Nakashima T Yamashita H Nishita T Tadamura K | 1994 | Computer Graphics Forum (EUROGRAPHICS94)1994，13，3： | 1 |
| 12 | Different gastoroesophageal reflux symptoms of middle-aged to elderly asthma and chronic obstructive pulmonary disease (COPD)patients显示文摘 | Shimizu Y Dobashi K Kusano M Mori M | 2012 | Jclin biochem nutr2012，50，2： | 1 |
| 13 | CD2+tetraploid acute promyelocytic leukemia variant with double(15;17)translocations显示文摘 | Kaito K Otsubo H Dobashi N | 2005 | Int J Hematol2005，81，1： | 1 |
| 14 | Structure of flames propagating through aluminum particles cloud and combustion process of particles显示文摘 | SUN J H DOBASHI R HIRANO T | 2006 | Journal of Loss Prevention In The Process Industries2006，19，6： | 1 |
| 15 | Kinetic modeling of thermal decomposition of natural cellulosic materials in air atmos- phere 显示文摘 | Liu N A Fan W Dobashi R | 2002 | Journal of Analytical and Applied Pyrolysis2002，63，2： | 1 |
| 16 | Contribution of neutrophil-derived myeloperoxidase in the early phase of fulminant acute respiratory distress syndrome induced by influenza virus infection显示文摘 | Sugamata Ryuichi Dobashi | 2012 | Microbiology and Immunology2012，56，3： | 1 |
| 17 | Menin,a product of th MENI gene,binds to estrogen receptor to enhance its activity in breast cancer cells:possibility of a novel predictive factor fo tamoxifen resistance显示文摘 | Imachi H Murao K Dobashi H | 2010 | Breast Cancer Res Treat2010，122，2： | 1 |
| 18 | Contribution of small GTPase Rho and its target protein Rock in a murine model of lung fibrosis显示文摘 | Shimizu Y Dobashi K Iizuka K | 2001 | Am J Respir Crit Care Med2001，163，1： | 1 |
| 19 | Effects ofnacetyl- cgsteineand ambroxol on IL-2 and IL-10 in human alveolar macrophagse 显示文摘 | Aihara M Dobashi K Akiyama M | 2000 | Respiratio2000，67，6： | 1 |
| 20 | Concentration profile of particles across a flame propagating through an iron particle cloud显示文摘 | Sun J H Dobashi R Hirano T | 2003 | Combustion and Flame2003，134，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员