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| 1 | Cryoablation of malignant liver tumors: results of a single center study显示文摘BACKGROUND: Local ablative procedures such as cryo-surgery and thermo-ablation are increasingly employed as a supplement to liver resection for the therapy of primary and secondary liver tumors. It is still unclear if the survival time can be extended through local ablative procedures. This prospective study shows operative actions, complications and long-term follow-up of 19 patients undergoing cryotherapy. METHODS: Between 1997 and 1998, 19 patients underwent cryotherapy due to a non-resectable malignant liver tumor (17 patients with metastases of a colon carcinoma, 2 patients with a hepatocellular carcinoma). Twelve patients (63.2%) received cryotherapy only and seven patients (36.8%) received a combination of resection and cryotherapy. The median follow-up period was 23 months. RESULTS: In a total of 59 liver tumors (18 were resected and 41 received cryotherapy), 12 had cryotherapy only, and 7 had a combination of cryotherapy and resection. The 30-day lethality was 0%, and the rate of major complications was 21%. After one year, 27.3% of the patients were still recurrence- free. The recurrence rate for all tumors treated was 58.8%. The median survival time for all patients was 21 months. The one- and three-year survival rates were 62. 5% and 15.8%, respectively. CONCLUSIONS: The mortality for cryotherapy is low, but there is a high rate of complications and long-term tumor control is not sufficient. If local ablative procedures of hepatic lesions are to be performed, not laparotomy but percutaneous, percutaneous thermoablation should be discussed as an alternative therapeutic measure. | Wolfgang Jungraithmayr Dieter Burger Manfred Olschewski Stefan Eggstein | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，4： | 26 |
| 2 | 牛疱疹病毒Ⅳ型(DN-599株)DNA的限制性酶切位点图及重复序列分析显示文摘牛疱疹病毒Ⅳ型(BHV-4)DNA片段分别被重组到质粒pUC9或pBR322的EcoRI、Hind Ⅲ和BamHⅠ位点中,用光生物素(Photobiotin)标记这些重组质粒作为探针,分别与转移到硝基纤维素膜上的病毒DNA的EcoRⅠ、Hind Ⅲ和BamHⅠ片段进行杂交,根据杂交结果及克隆的BHV-4DNA片段的双酶切分析,画出了病毒DNA的EcoRⅠ、Hind Ⅲ和BamHⅠ位点图,井证明在病毒DNA的两末端含有多聚重复序列,左侧含12个重复单位,右侧含6个重复单位,两侧重复单位的排列方向相同,重复单位的大小为2.35kb。病毒DNA分子无任何异构体. | 童光志 Dieter Burger David T.Shen | 1990 | 病毒学报1990，6，2： | 8 |
| 3 | 牛疱疹病毒Ⅳ型(DN-599株)DNA的分子克隆显示文摘从感染的MDBK(牛肾)细胞中直接抽提出牛疱疹病毒IV型(BHV-4)DNA。分别经限制性内切酶EcoRⅠ,HindⅢ或BamHI消化后,用鸟枪法和选择法将病毒DNA片段克隆到质粒pBR322和pUC9的相应位点中,构建了三组病毒DNA基因库。阳性克隆是用光生物素标记的病毒DNA和牛胸腺细胞DNA与各重组质粒DNA杂交而筛选的。总共克隆了病毒基因组的94%,其中用EcoRI克隆了83.4%,BamHI克隆了63.4%,HindIlI克隆了45%。 | 童光志 Dieter Burger David T Shen | 1990 | 病毒学杂志1990，4，4： | 4 |
| 4 | 牛传染性鼻气管炎病毒LA株DNA的分子克隆显示文摘本实验用鸟枪法和选择法将牛传染性鼻气管炎病毒(IBRV)的LA株DNA克隆到载体质粒pBR325,pBR322或pUC_9的HindⅢ位点中。经用光生物素标记的IBR DNA和牛胸腺细胞DNA与各重组质粒杂交筛选后,共得到10个病毒DNA的HindⅢ片段,分别是A,B,C,E,G,I,J,K,L和M,克隆的DNA占全病毒DNA的89.5%。 | 童光志 Dieter Burger | 1990 | 中国兽医科技1990，，7： | 3 |
| 5 | Ki‐67, mini‐chromosome maintenance 2 protein ( MCM2 ) and geminin have no independent prognostic relevance for cancer‐specific survival in surgically treated squamous cell carcinoma of the penis显示文摘 | Matthias May Maximilian Burger Wolfgang Otto Oliver W. Hakenberg Wolf F. Wieland Dieter May Ferdinand Hofst?dter Stefanie G?tz Nina Niessl Hans‐Martin Fritsche Kristina Birnkammer Christian Gilfrich Julia Peter Anjun Jain Stefan Koch Steffen Lebentrau Hub | 2013 | BJU Int2013，，4： | 1 |
| 6 | Photodynamic Diagnosis of Non–muscle-invasive Bladder Cancer with Hexaminolevulinate Cystoscopy: A Meta-analysis of Detection and Recurrence Based on Raw Data显示文摘 | Maximilian Burger H. Barton Grossman Michael Droller Joerg Schmidbauer Gregers Hermann Octavian Dr?goescu Eleanor Ray Yves Fradet Alexander Karl Juan Pablo Burgués J. Alfred Witjes Arnulf Stenzl Patrice Jichlinski Dieter Jocham | 2013 | European Urology2013，，： | 1 |
| 7 | Synthesis of linear oligomers of -3-hydroxybutyrate and solid-state structural investigations by electron microscopy and X-ray scattering显示文摘 | DIETER SEEBACH MICHESL BURGER H | 1994 | Hevetica Chimica Acta1994，，77： | 1 |
| 8 | Pulmonary manifestations of wegener granulomatosis: CT findings in 57 patients and a review of the literature显示文摘 | Christian Lohrmann Markus Uhl Elmar Kotter Dieter Burger Nadir Ghanem Mathias Langer | 2004 | European Journal of Radiology2004，，3： | 1 |
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