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| 1 | A Mathematical Study on Three Layered Oscillatory Blood Flow Through Stenosed Arteries显示文摘 | Dharmendra Tripathi | 2012 | Journal of Bionic Engineering2012，9，1： | 5 |
| 2 | DTM Simulation of Peristaltic Viscoelastic Biofluid Flow in Asymmetric Porous Media: A Digestive Transport Model显示文摘 | Dharmendra Tripathi Osman Anwar Beg Praveen Kumar Gupta Ganjam Radhakrishnamacharya Jagannath Mazumdar | 2015 | Journal of Bionic Engineering2015，12，4： | 4 |
| 3 | Analytical approach to entropy generation and heat transfer in CNT-nanofluid dynamics through a ciliated porous medium显示文摘The transportation of biological and industrial nanofluids by natural propulsion like cilia movement and self-generated contraction-relaxation of flexible walls has significant applications in numerous emerging technologies. Inspired by multi-disciplinary progress and innovation in this direction, a thermo-fluid mechanical model is proposed to study the entropy generation and convective heat transfer of nanofluids fabricated by the dispersion of single-wall carbon nanotubes(SWCNT) nanoparticles in water as the base fluid. The regime studied comprises heat transfer and steady, viscous, incompressible flow, induced by metachronal wave propulsion due to beating cilia, through a cylindrical tube containing a sparse(i.e., high permeability) homogenous porous medium. The flow is of the creeping type and is restricted under the low Reynolds number and long wavelength approximations. Slip effects at the wall are incorporated and the generalized Darcy drag-force model is utilized to mimic porous media effects. Cilia boundary conditions for velocity components are employed to determine analytical solutions to the resulting non-dimensionalized boundary value problem. The influence of pertinent physical parameters on temperature, axial velocity, pressure rise and pressure gradient, entropy generation function, Bejan number and stream-line distributions are computed numerically. A comparative study between SWCNT-nanofluids and pure water is also computed. The computations demonstrate that axial flow is accelerated with increasing slip parameter and Darcy number and is greater for SWCNT-nanofluids than for pure water. Furthermore the size of the bolus for SWCNT-nanofluids is larger than that of the pure water. The study is applicable in designing and fabricating nanoscale and microfluidics devices, artificial cilia and biomimetic micro-pumps. | Noreen Sher Akbar M.Shoaib Dharmendra Tripathi Shashi Bhushan O.Anwar Bég | 2018 | Journal of Hydrodynamics2018，30，2： | 1 |
| 4 | Impacts of fly-ash on soil and plant responses显示文摘 | Dharmendra K Gupta Upendra N Rai Rudra D Tripathi | 2002 | Journal of Plant Research2002，115，6： | 1 |
| 5 | A cross-sectional study on thyroid status in North Indian elderly outpatients with dementia显示文摘 | Rachna Agarwal Suman Kushwaha Neelam Chhillar Alok Kumar Dharmendra Dubey Chandra Tripathi | 2013 | Annals of Indian Academy of Neurology2013，，3： | 1 |
| 6 | Evaluation of antimicrobial activity and bronchodialator effect of a polyherbal drug-Shrishadi显示文摘Objective:To investigate antimicrobial and bronchodialator effect of hydroalcholic extract of polyherbal drug Shirishadi containing Shirisha(Albezzia lebbeck),Nagarmotha(Cyprus ratandus) & Kantakari(Solanum xanthocarpum).Methods:Antimicrobial activity was evaluated by discdiffusion method and MIC,MBC,MFC were calculated by micro dilution method.Hydroalcholic extract of this preparation was investigated for its phytochemical analysis,phenol and Oavonoid were determined by speclrophotometric method and in vivo bronchodilator effect was analysed by convulsion time.Results:The phytochemical tests revealed presence of alkaloids, anthraquinones,carbohydrates,flavonoids,saponins and tannins.The antimicrobial result showed the MIC of 6.25 mg/ml.against Staphylococcus aureus and 12.5 mg/mL.for Escherichia coli and 12.5 mg/mL against remaining bacteria tested,with strong antifungal activity.The maximum inhibition zone is found against Pseudomonas aeruginosa with MIC 16 mg/mL Drug showed significant bronchodilator effect with 27.86%& 36.13%increase in preconvulsion time of guinea pigs prebeated with 100 & 200 mg/kg body weight of extract.Conclusions:The study reveals that the extracts possess antibacterial activity and antifungal activity in a dose dependent manner. This antimicrobial property may be due to presence of several saponins,further studies are highly needed for the drug development. | Divya Kumari Kajaria Mayank Gangwar Dharmendra Kumar Amit Kumar Sharma Ragini Tilak Gopal Nath Yamini Bhusan Tripathi JS Tripathi SK Tiwari | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，11： | 0 |
| 7 | Anti-cancer effects of sitagliptin,vildagliptin,and exendin-4 on triple-negative breast cancer cells via mitochondrial modulation显示文摘Triple-negative breast cancer(TNBC)cell line MDA-MB-231 is known for Warburg metabolism and defects in mitochondria.On the other hand,dipeptidyl peptidase-IV(DPP-IV)inhibitors such as sitagliptin and vildagliptin and GLP-1 agonist exendin-4 are known to improve mitochondrial functions as well as biogenesis,but no study has evaluated the influence of these drugs on mitochondrial biogenesis on metastatic breast cancer cell line.We have recently reported anticancer effects of 5-aminoimidazole-4-carboxamide riboside on MDA-MB-231 cells via activation of AMP-dependent kinase(AMPK),which activates the downstream transcription factors PGC-1α,PGC-1β,or FOXO1 for mitochondrial biogenesis;above-mentioned incretin-based therapies are also known to activate AMPK.This study evaluated the effects of sitagliptin,vildagliptin,and exendin-4 on MDA-MB-231 cells and the underlying changes in mitochondrial biogenesis,were examined.Treatment with sitagliptin(100μM),vildagliptin(100μM),and exendin-4(10 nM)for 72 h to MDA-MB-231 cells led to a decrease in viability indicated by MTT assay,cell migration by scratch,and transwell migration assays,accompanied with marginal reduction in cell numbers along with the apoptotic appearance,the rate of apoptosis,and decreased lactate content in conditioned medium.These changes in the cancer phenotype were accompanied by an increase in the mitochondrial DNA to nuclear DNA ratio,increased MitoTracker green and red staining,and increased expression of transcription factors PGC-1α,NRF-1,NRF-2,TFAM,and HO-1.Pre-treatment of cells with these incretin-based drugs followed by 48 h treatment with 1μM doxorubicin increased doxorubicin sensitivity as observed by a decrease in viability by MTT assay.Thus,sitagliptin,vildagliptin,and exendin-4 exert their beneficial effects on TNBC cells via an increase in mitochondrial biogenesis that helps to switch Warburg metabolism into anti-Warburg effect.Therapeutic response was in the order of:sitagliptin>vildagliptin>exendin-4. | POOJA JAISWAL VERSHA TRIPATHI ANSHUL ASSAIYA DHARMENDRA KASHYAP RAHUL DUBEY ANAMIKA SINGH JANESH KUMAR HEM CHANDRA JHA RAJESH SHARMA AMIT KUMAR DIXIT HAMENDRA SINGH PARMAR | 2022 | BIOCELL2022，46，12： | 0 |
| 8 | Transient peristaltic diffusion of nanofluids: A model of micropumps in medical engineering显示文摘Peristaltic micro-pumps offer an excellent mechanism for delivery of a variety of medicines including drugs, corneal solutions etc. The surge in deployment of nanoparticles in medicine has provided new potential for such pumps. In light of this we investigate the time-dependent peristaltic flow of nanofluids with diffusive effects through a finite non-uniform channel, this geometry being more representative of real micro-pumps. Creeping flow is taken into account(inertial forces are small compared with viscous forces) i.e., Reynolds number is low(Re< 1) and wavelength is also taken to be very large. The Buongiorno formulation for nanofluids is employed with an Oberbeck-Boussinesq approximation. Closed-form solutions are developed for the non-dimensional governing equations subject to physically realistic boundary conditions. Mathematica symbolic software is employed to evaluate the evolution of nanoparticle fraction, temperature, axial velocity, transverse velocity and pressure difference distribution along the length of the pump channel with variation in thermal Grashof number, basic-density(species i.e., mass) Grashof number, Brownian motion parameter and thermophoresis parameter. | Dharmendra Tripathi Shashi Bhushan O.Anwar Bég Noreen Sher Akbar | 2018 | Journal of Hydrodynamics2018，30，6： | 0 |
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