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| 1 | Mitochondrial PKM2 regulates oxidative stress-induced apoptosis by stabilizing Bcl2显示文摘 | Ji Liang Ruixiu Cao Xiongjun Wang Yajuan Zhang Pan Wang Hong Gao Chen Li Fan Yang Rong Zeng Ping Wei Dawei Li Wenfeng Li Weiwei Yang | 2017 | Cell Research2017，27，3： | 39 |
| 2 | The mechanisms of sorafenib resistance in hepatocellular carcinoma:theoretical basis and therapeutic aspects显示文摘Sorafenib is a multikinase inhibitor capable of facilitating apoptosis,mitigating angiogenesis and suppressing tumor cell proliferation.In late-stage hepatocellular carcinoma(HCC),sorafenib is currently an effective first-line therapy.Unfortunately,the development of drug resistance to sorafenib is becoming increasingly common.This study aims to identify factors contributing to resistance and ways to mitigate resistance.Recent studies have shown that epigenetics,transport processes,regulated cell death,and the tumor microenvironment are involved in the development of sorafenib resistance in HCC and subsequent HCC progression.This study summarizes discoveries achieved recently in terms of the principles of sorafenib resistance and outlines approaches suitable for improving therapeutic outcomes for HCC patients. | Weiwei Tang Ziyi Chen Wenling Zhang Ye Cheng Betty Zhang Fan Wu Qian Wang Shouju Wang Dawei Rong F.P.Reiter E.N.De Toni Xuehao Wang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 19 |
| 3 | Planning and analysis of the demonstration project of the MVDC distribution network in Zhuhai显示文摘The DC distribution system is an important development direction of the distribution system,which can improve the reliability and the quality of the power supply,and support the new energy,the energy storage,the electric vehicles,and the flexible access of AC and DC loads to grid.To realize the demonstration application of the DC distribution technology,China's first demonstration project of the medium voltage DC distribution network will be built in Zhuhai,Guangdong Province to support the construction of the city energy internet.First,this paper analyzes the demand of the DC distribution network project,and puts forward the construction content and construction target.Then,it designs and analyzes the electrical connection mode,system operation mode,and startup and shutdown mode of the DC distribution network,and proposes the overall project construction plan.Finally,it conducts the specific project design and analysis,which mainly in elude the selection of equipment such as inverters,DC transformers and DC circuit breakers,the design and analysis of the DC control and protection system,the design and analysis of the overvoltage protection and the configuration scheme of the lightning arrester,and analysis of the system transient characteristics.The design and analysis of the engineering program is a combination of China's distribution network engineering practice and technical characteristics,which lays a solid foundation for the advancement of the DC power distribution technology in China,and has reference value and demonstration effect for the design and construction of other projects. | Lu QU Zhanqing YU Qiang SONG Zhichang YUAN Biao ZHAO Dawei YAO Jianfu CHEN Yao LIU Rong ZENG | 2019 | Frontiers in Energy2019，13，1： | 7 |
| 4 | Measure of Watershed Ecological Compensation Standard Based on WTP and WTA显示文摘In this paper,Liao River Basin was taken as the research object and field surveys were conducted in Fudedian,the source of Liao river mainstream and Panjin,the estuary of Liao River. Through the questionnaires,the willingness to pay ( WTP) and willingness to accept ( WTA) of the residents in Liao River Basin were analyzed. Then based on analysis of the existing ecological compensation standard measuring methods,the WTP and WTA using contingent valuation method ( CVM) were measured and analyzed. Without considering other factors,and based on using the nonparametric estimation method,it was concluded the ecological compensation standard of Liao River Basin was 160. 72 yuan/person·years. When considering other factors,using the parametric estimation we obtain that the ecological compensation standard of Liao River Basin was 255. 97 yuan/person·years. Measuring the respondents' WTP and WTA at the same time and processing the average can actually reflect the respondents' real WTP,thus to a certain extent solving the problems of high compensation caused by formulating ecological compensation standards according to measuring WTP of respondents separately. In addition,the policy suggestions have been proposed from three aspects including financial transfer payment,ecological compensation forms and public participation system. This will not only protect residents' right to know and strengthen public participation and supervision,but also benefit the comprehensive implementation of ecological environment of Liao River Basin and establishment of a long-term mechanism of water resources protection. | Dawei XU Jinfang RONG Na YANG Wen ZHANG | 2013 | Asian Agricultural Research2013，5，7： | 1 |
| 5 | Dynamic compressive response and failure behavior of fiber polymer composites embedded with tetra needle- like ZnO nanowhiskers 显示文摘 | Cao Maosheng Song Weili Zhou Wei Wang Dawei Rong Jill Yuan Jie Agathopoulos Simeon | 2010 | Composite Structures2010，92，12： | 1 |
| 6 | The preoperative neutrophil–lymphocyte ratio predicts recurrence and survival among patients undergoing R0 resections of adenocarcinomas of the esophagogastric junction显示文摘 | Dawei Yuan Kun Zhu Kang Li Rong Yan Yong Jia Chengxue Dang | 2014 | J. Surg. Oncol2014，，3： | 1 |
| 7 | Stereo mapping of Ming Great Wall with remote sensing显示文摘Listed by UNESCO in 1987 as a World Heritage site,the world-famous Ming Great Wall stretches several thousands of kilometers across northern China,and served as a massive military defensive system which in recent times has a unique historical,artistic and scientific value.Due to historical reasons and lack of advanced technologies,construction resources and conservation status of Ming Great Wall have not been investigated in any systematic manner;indeed,the extent of the Great Wall has not even been measured.This has resulted in a shortage of reliable first-hand scientific information on actual size,spatially resource distribution and preservation status of this World Heritage site.Driven by the urgent need to establish protection,research,renovation and management of Ming Great Wall,a comprehensive investigation and spatial mapping was jointly organized and completed by the State Bureau of Survey and Mapping and State Administration of Culture Heritage.High resolution digital stereo models at 1:10000 map scale covering the whole length of the Ming Great Wall have been created by photogrammetric reconstruction using nearly ten thousand aerial images.Spatial distribution and attributes of the wall sections,trenches and various subsidiary facilities in the surroundings of the Great Wall were measured with the help of digital photogrammetry workstations and results from field studies.Reliable and precise information about the Ming Great Wall has now been obtained and documented,including surface lengths,resource distribution,and preservation status.For example,the total length of Ming Great Wall is 8851.8 km,of which 6259.6 km is of actual wall,2232.5 km of natural terrain,and 359.7 km of trenches.In category lengths,1828.8 km is constructed of stone,3411.3 km of earth,249.6 km in brick,197.5 km of cliff wall and the rest 572.4 km of other means.Such information provides the scientific basis and strong platform in helping to delineate areas needing protection,in planning conservation and renovation programs,as well as digital archiving for posterity and web-based applications for modern promotions of one of the world's great attractions,the Ming Great Wall. | CHEN Jun JIN ShuPing LIAO AnPing ZHAO YouSong ZHANG HongWei RONG DaWei YANG ZhaoJun | 2010 | Chinese Science Bulletin2010，55，21： | 1 |
| 8 | Reverse leakage current in AlGaN-based ultraviolet light-emitting diodes显示文摘The reverse leakage characteristics of AlGaNbased ultraviolet light-emitting diodes fabricated on sapphire substrate are studied by temperature-variable current–voltage(I–V)measurement from 300 to 450 K.At low-reverse bias range(0–0.5 V),the reverse leakage current exhibits tunneling characteristics.Meanwhile,under a more negative reverse bias range([0.5 V),the log(I)–log(V)plots exhibit close-to-linear dependency,which is in good agreement with the transport mechanism of space-charge limited current.A phenomenological leakage current model focusing on electron transmission primarily through continuous defect band formed by linear defects like dislocations is suggested to explain the reverse current–voltage characteristics. | Rong Jiang Dawei Yan Hai Lu Rong Zhang Dunjun Chen Youdou Zheng | 2014 | Chinese Science Bulletin2014，59，12： | 1 |
| 9 | Multicomponent SF6 decomposition product sensing with a gas-sensing microchip显示文摘A difficult issue restricting the development of gas sensors is multicomponent recognition. Herein, a gas-sensing (GS) microchip loaded with three gas-sensitive materials was fabricated via a micromachining technique. Then, a portable gas detection system was built to collect the signals of the chip under various decomposition products of sulfur hexafluoride (SF6). Through a stacked denoising autoencoder (SDAE), a total of five high-level features could be extracted from the original signals. Combined with machine learning algorithms, the accurate classification of 47 simulants was realized, and 5-fold cross-validation proved the reliability. To investigate the generalization ability, 30 sets of examinations for testing unknown gases were performed. The results indicated that SDAE-based models exhibit better generalization performance than PCA-based models, regardless of the magnitude of noise. In addition, hypothesis testing was introduced to check the significant differences of various models, and the bagging-based back propagation neural network with SDAE exhibits superior performance at 95% confidence. | Jifeng Chu Aijun Yang Qiongyuan Wang Xu Yang Dawei Wang Xiaohua Wang Huan Yuan Mingzhe Rong | 2021 | Microsystems & Nanoengineering2021，7，2： | 1 |
| 10 | Identification of Avian-Derived Ingredients in Livestock and Poultry Meat by PCR Technology显示文摘In order to establish a quick and specific method which could identify the avian-derived ingredients,this study used 16 S rRNA gene sequence as target site,and designed the specific primers of chicken,pigeon meat and quail meat. The DNA of common livestock and poultry meat( including mutton,beef,pork,rabbit meat,pigeon meat,quail meat,chicken,duck and goose) was used as template. Though PCR amplification and specific detection,a quick determination method was established to identify the avian-derived ingredients. The results showed that the selected primers could identify the ingredients of animal origin effectively and quickly. The method was convenient and concise,and could detect the chicken-derived,pigeon-derived,quail-derived ingredients in livestock and poultry food quickly and accurately. | Jingxin ZHANG Yushi GAO Xiujun TANG Yanfeng FAN Mengjun TANG Dawei CHEN Qinglian GE Rong GU | 2016 | Asian Agricultural Research2016，8，12： | 0 |
| 11 | Phenotype,Physiology,and Gene Expression of Barley Seedlings in Response to Nano Zinc Oxide Stress显示文摘In recent years,zinc oxide nanoparticles(ZnO NPs)have been widely used as zinc fertilizers and pesticides.The use of ZnO NPs in this way can provide benefits to humans,but also has potential risks.ZnO NPs inevitably enter the environment during their production and use,which affects the ecological environment and crop growth.In order to investigate the phenotype,physiology,and gene expression of barley(Hordeum vulgare L.)seedlings under ZnO NPs stress,the barely cultivars ZJU3(P21),Golden Promise(GP)and L23 were chosen for study.Different ZnO NPs concentrations were applied to compare the physiological and biochemical indexes of the barley seedlings and the responses of six stress-related genes,when seedlings were cultured to the two-leaf stage through hydroponics.The results showed that the density of brown spots on the leaf surface increased with increasing ZnO NPs concentration.ZnO NPs stress inhibited the root growth of barley seedlings,and P21 was the most sensitive.Furthermore,ZnO NPs stress could stimulate plants to produce a large number of reactive oxygen species(ROS),resulting in an imbalance between the production and removal of ROS and membrane lipid peroxidation in plants.This imbalance inhibited the growth and development of the barley seedlings.With increasing ZnO NPs concentration,the activity of superoxide dismutase was gradually increased,the activity of catalase was progressively decreased,and the contents of malondialdehyde and proline were increased.Compared with the control,among six stress-related genes,the expression levels of five genes were downregulated and one gene was upregulated in the experimental group.This study preliminarily revealed the toxic effect of ZnO NPs on seedlings and the effect on the expression of stress-related resistance genes in different barley varieties. | Mengyuan Dong Rong Sun Qianhui Yang Lantian Zhang Yangying Yong Yunxia Fang Xian Zhang Xiaoqin Zhang Dawei Xue | 2021 | Phyton-International Journal of Experimental Botany2021，90，6： | 0 |
| 12 | Observation of Zeeman splitting effect in a laser-driven coil显示文摘The Zeeman splitting effect is observed in a strong magnetic field generated by a laser-driven coil.The expanding plasma from the coil wire surface is concentrated at the coil center and interacts with the simultaneously generated magnetic field.The Cu I spectral lines at wavelengths of 510.5541,515.3235,and 521.8202 nm are detected and analyzed.The splittings of spectral lines are used to estimate the magnetic field strength at the coil center as∼31.4±15.7 T at a laser intensity of∼5.6310^(15) W/cm^(2),which agrees well with measurements using a B-dot probe.Some other plasma parameters of the central plasma disk are also studied.The temperature is evaluated from the Cu I spectral line intensity ratio,while the electron density is estimated from the Stark broadening effect. | Baojun Zhu Zhe Zhang Chang Liu Dawei Yuan Weiman Jiang Huigang Wei Fang Li Yihang Zhang Bo Han Lei Cheng Shangqing Li Jiayong Zhong Xiaoxia Yuan Bowei Tong Wei Sun Zhiheng Fang Chen Wang Zhiyong Xie Neng Hua Rong Wu Zhanfeng Qiao Guiyun Liang Baoqiang Zhu Jianqiang Zhu Shinsuke Fujioka Yutong Li | 2022 | Matter and Radiation at Extremes2022，7，2： | 0 |
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