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| 1 | Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products显示文摘最近的婴儿的公式奶粉污染事件证明了在牛奶质量控制的经典标记或标准在识别鈥渕a nipulated 鈥 ? 是不够的差质量的牛奶。在现在的学习,我们第一次证明奶牛牛奶包含大量 microRNAs ( miRNAs )并且牛奶特定的 miRNAs 的唯一的表示侧面能为未加工的牛奶和牛奶相关的商业产品的质量控制用作新奇指示物和可能的新标准,例如液体牛奶和粉状的公式牛奶。用定序的 Solexa,首先,我们系统地在未加工的牛奶屏蔽了 miRNA 表示并且在未加工的牛奶识别了 245 miRNAs 的一个总数。不同于层次在哺乳的不同时期是其表达式将近相同的另外的经典 biomarkers,单个 miRNAs 能显著地在哺乳过程期间被改变,含有那 miRNAs 可以是更精确的指示物反映牛奶的优秀改变。第二,使用 TaqMan 基于探查的 miRNA 量的 RT-PCR ,我们进一步识别了七 miRNAs 重要地在整个哺乳过程,和更多有相对一致的表情,这七牛奶特定的 miRNAs 的表示侧面能为区别用作理想的 biomarker 差质量或从纯未加工的牛奶的 鈥渕a nipulated 鈥?牛奶,象为商业乳制品的质量控制一样,例如液体,牛奶和粉状的公式挤。一起,我们的调查结果为为决定未加工的牛奶或牛奶相关的商业产品的质量理解牛奶 miRNAs 和一个新潜在的标准的生理的角色提供一个基础。 | Xi Chen Chao Gao Haijin Li Lei Huang Qi Sun Yanye Dong Chunliang Tian Shengpu Gao Hailin Dong Danping Guan Xiaoyun Hu Shujian Zhao Liang Li Lin Zhu Qiao Yan Junfeng Zhang Ke Zen Chen-Yu Zhang | 2010 | Cell Research2010，20，10： | 29 |
| 2 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021，31，4： | 16 |
| 3 | Small non-coding RNAs transfer through mammalian placenta and directly regulate fetal gene expression显示文摘 | Jing Li Yujing Zhang Dameng Li Yuchen Liu Danping Chu Xiaohong Jiang Dongxia Hou Ke Zen Chen-Yu zhang | 2015 | Protein & Cell2015，6，6： | 9 |
| 4 | The effect of integrative crop management on root growth and methane emission of paddy rice显示文摘In previous studies, integrative crop management (ICM) improved shoot growth and grain yield of rice (Oryza sativa L.). However, little is known about the effect of ICM on root growth and methane (CH4) emission of paddy rice. In this study, two rice varieties, Wuyunjing 24 and Yongyou 2640, were grown. A field experiment was conducted with three crop management treatments including zero nitrogen fertilization (0N), local farmer practice (LFP), and ICM. Root morphophysiological traits and CH4 emission from the paddy field were investigated. ICM significantly increased mean grain yield by 29.9%, with the effect attributed mainly to an increase in mean total number of spikelets by 26.4% compared to LFP. ICM increased root and shoot biomass, root length, number of roots, root oxidation activity (ROA), root bleeding rate, and root total and active absorbing surface area by respectively 24.4%, 25.7%, 17.1%, 9.3%, 18.7%, 29.5%, 12.1%, and 24.7%. The concentrations of malic, succinic, and acetic acids in root exudates were respectively 5.8%, 6.0%, and 10.5% higher in ICM than in LFP. Compared to LFP, ICM significantly decreased the rate of CH4 emission during emission peak stages and reduced total CH4 emission by 17.1%. The root morphophysiological traits were positively and significantly correlated with grain yield, whereas root length, specific root length, ROA, and root total and active absorbing surface area were negatively and significantly correlated with total CH4 emission. These results suggest that ICM could achieve the dual goals of increasing grain yield and reducing the greenhouse gas effect by improving the root morphology and physiological traits of paddy rice. | Hao Zhang Hailang Liu Danping Hou Yilei Zhou Mengzhu Liu Zhiqin Wang Lijun Liu Junfei Gu Jianchang Yang | 2019 | The Crop Journal2019，7，4： | 8 |
| 5 | Chaperone proteins identified from synthetic proteasome inhibitor-induced inclusions in PC12 cells by proteomic analysis显示文摘女伴蛋白质在 Lewy 身体是重要的,但是女伴蛋白质的侧面不完全地被解开。Proteomic 分析被用来为进一步的学习决定蛋白质候选人。这里,从导致代理人的包括识别潜在的女伴蛋白质,我们执行了包括在为 48 h 暴露于 10 M 希腊语的第二十三个字母的 PC12 房间形成了的导致的人工地合成的 proteasome 禁止者(希腊语的第二十三个字母) 的 proteomic 分析。用通过指纹对多重蛋白质数据库寻找了的肽质量的生物化学的分别, 2-D 电气泳动,和鉴定,我们反复从导致希腊语的第二十三个字母的包括识别了八可再现的女伴蛋白质。这些, 58 kDa 葡萄糖调整了蛋白质, 75 kDa 葡萄糖调整了蛋白质,并且钙绑定蛋白质 1 是最新识别了。其它五被报导了是 Lewy 身体的一致部件。这些调查结果建议三潜在的女伴蛋白质可能在 proteasome 抑制下面在 PC12 房间被招募到导致希腊语的第二十三个字母的包括。 | Xing'an Li Yingjiu Zhang Yihong Hu Ming Chang Tao Liu Danping Wang Yu Zhang Lei Zhang Linsen Hu | 2008 | Acta Biochimica et Biophysica Sinica2008，40，5： | 4 |
| 6 | Ultraflat, broadband, and highly coherent supercontinuum generation in all-solid microstructured optical fibers with all-normal dispersion显示文摘High flatness, wide bandwidth, and high-coherence properties of supercontinuum(SC) generation in fibers are crucial in many applications. It is challenging to achieve SC spectra in a combination of the properties, since special dispersion profiles are required, especially when pump pulses with duration over 100 fs are employed. We propose an all-solid microstructured fiber composed only of hexagonal glass elements. The optimized fiber possesses an ultraflat all-normal dispersion profile, covering a wide wavelength interval of approximately 1.55 μm. An SC spectrum spanning from approximately 1030 to 2030 nm(corresponding to nearly one octave) with flatness<3 dB is numerically generated in the fiber with 200 fs pump pulses at 1.55 μm. The results indicate that the broadband ultraflat SC sources can be all-fiber and miniaturized due to commercially achievable 200-fs fiber lasers. Moreover, the SC pulses feature high coherence and a single pulse in the time domain, which can be compressed to 13.9-fs pulses with high quality even for simple linear chirp compensation. The Fourier-limited pulse duration of the spectrum is 3.19 fs, corresponding to only 0.62 optical cycles. | CHUNLEI HUANG MEISONG LIAO WANJUN BI XIA LI LILI HU LONG ZHANG LONGFEI WANG GUANSHI QIN TIANFENG XUE DANPING CHEN WEIQING GAO | 2018 | Photonics Research2018，6，6： | 4 |
| 7 | WheatGmap:a comprehensive platform for wheat gene mapping and genomic studies显示文摘Bulked segregant analysis(BSA)is an efficient and low-cost strategy that is widely used to identify causal genes in segregating populations.BSA-based methods,such as BSA sequencing(Wenger et al.,2010),bulked segregant RNA sequencing(BSR-seq)(del Viso et al.,2012),and MutMap(Abe et al.,2012),are powerful tools that can be used for rapidly discovering genetic markers and gene mapping.Although BSA is increasingly being used in wheat(Triticum aestivum)gene mapping efforts,few user-friendly BSA tools have been developed for researchers lacking a strong bioinformatics background.Here,we developed the web-based BSA platform WheatGmap(http://gffzz4d94446f6f524399skccff6bfvb0u6qqv.ffgz.tsg.suse.edu.cn),which integrates multiple BSA mapping models and large amounts of public data to accelerate gene cloning and functional research and facilitate resource sharing. | Lichao Zhang Chunhao Dong Zhongxu Chen Lixuan Gui Cheng Chen Danping Li Zhencheng Xie Qiang Zhang Xueying Zhang Chuan Xia Xu Liu Xiuying Kong Jirui Wang | 2021 | Molecular Plant2021，14，2： | 4 |
| 8 | Vehicle-to-Infrastructure Channel Characterization in Urban Environment at 28 GHz显示文摘Both ultra-reliable low latency and high-data-rate communications are required by connective vehicles. Millimeter wave(mm Wave) with large bandwidth is a key technology to support high-data-rate communications. In this paper, the 28 GHz wideband vehicle-to-infrastructure channel is characterized for the urban environment in a major street in Manhattan. The deployment of the transmitter and the receiver, as well as the traffic models, are selected by considering the recommendation by 3GPP TR 37.885. Ray tracing simulator with calibrated electromagnetic parameters is employed in this work to practically conduct intensive simulations. The 3D environment model is reconstructed from OpenStreetMap. The power delay profile, path loss, root-meansquare delay spread, K-factor and so on, are extracted from the calibrated simulation results. The evolution of the parameters, as well as their statistical properties, are analyzed and modeled. The work of this paper helps the researchers understand the propagation channel for designing mmWave technologies and communication system in a similar scenario. | Longhe Wang Bo Ai Danping He Ke Guan Jiayi Zhang Junhyeong Kim Zhangdui Zhong | 2019 | China Communications2019，16，2： | 3 |
| 9 | Blue revolution for food security under carbon neutrality: A case from the water-saving and drought-resistance rice显示文摘The increasing concentration of greenhouse gases(GHGs)in Earth's atmosphere leads to global warming,which further causes a series of climate changes and does great harm to both human society and natural ecosystems.Agricultural GHG emissions,mainly in theform of methane(CH4)and nitrous oxide(N2O),areasignificantsourceofGHGs,accountingfor~14%total global GHGs(Zhang et al.,2022).One major source of agricultural GHGs is CH4 emissions from rice paddies,which is responsiblefor~10%-12%ofhuman-inducedCH4emissions(van Groenigen et al.,2013)and contributes~2.40%to the enhanced global warming effect(Zhang et al.,2022).The global warming potential of GHGs emissions from rice systems is roughly four times higher than either wheat or maize(Linquist et al.,2012). | Hui Xia Xianxian Zhang Yi Liu Junguo Bi Xiaosong Ma Anning Zhang Hongyan Liu Liang Chen Sheng Zhou Huan Gao Kai Xu Haibin Wei Guolan Liu Feiming Wang Hongyang Zhao Xingxing Luo Danping Hou Qiaojun Lou Fangjun Feng Liguo Zhou Shoujun Chen Ming Yan Tianfei Li Mingshou Li LeiWang Zaochang Liu Xinqiao Yu HanweiMei Lijun Luo | 2022 | Molecular Plant2022，15，9： | 3 |
| 10 | The application of label-free imaging technologies in transdermal research for deeper mechanism revealing显示文摘The penetration behavior of topical substances in the skin not only relates to the transdermal delivery efficiency but also involves the safety and therapeutic effect of topical products,such as sunscreen and hair growth products.Researchers have tried to illustrate the transdermal process with diversified theories and technologies.Directly observing the distribution of topical substances on skin by characteristic imaging is the most convincing approach.Unfortunately,fluorescence labeling imaging,which is commonly used in biochemical research,is limited for transdermal research for most topical substances with a molecular mass less than 500 Da.Label-free imaging technologies possess the advantages of not requiring any macromolecular dyes,no tissue destruction and an extensive substance detection capability,which has enabled rapid development of such technologies in recent years and their introduction to biological tissue analysis,such as skin samples.Through the specific identification of topical substances and endogenous tissue components,label-free imaging technologies can provide abundant tissue distribution information,enrich theoretical and practical guidance for transdermal drug delivery systems.In this review,we expound the mechanisms and applications of the most popular label-free imaging technologies in transdermal research at present,compare their advantages and disadvantages,and forecast development prospects. | Danping Zhang Qiong Bian Yi Zhou Qiaoling Huang Jianqing Gao | 2021 | Asian Journal of Pharmaceutical Sciences2021，16，3： | 2 |
| 11 | LiFePO_4/C via fluoride doping显示文摘Non-stoichiometric compound fluoride-doped LiFePO4/C cathode materials were synthesized via solid-state reaction using MgF2 and AlF3 as dopant. The fluoride-doped LiFePO4/C samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and electrochemical testing. The results show that the materials are well crystallized and fluoride doping cannot change the space structure of LiFePO4. Slight amounts of Fe2O3 with no fluoride impurity were detected. Charge-discharge curves show that fluoride-doped samples have higher capacity at low rates compared with undoped LiFePO4/C. AlF3-doped samples have highest capacity at high discharge current. Both doped samples have larger polarization voltage than undoped samples. All samples exhibit good cycle stability. | Gu Yuan Zhang Xiangjun Lu Shigang Zhao Ting Jiang Danping Yang Rong Wu Aide | 2012 | Rare Metals2012，31，6： | 2 |
| 12 | A new MMOCAA-MFE method for compressible miscible displacement in porous media显示文摘 | Zhang Jiansong Yang Danping Shen Shuqian | 2014 | Applied Numerical Mathematics2014，80，3： | 1 |
| 13 | A splitting positive definite mixed element method for second order hyperbolic equations显示文摘 | Zhang Jiansong Yang Danping | 2009 | Numer Meth Part Differ Eqs2009，25，3： | 1 |
| 14 | Constraints on the depth,geometry and kinematics of blind detachment faults provided by fault-propagation folds:An example from the Mesozoic fold belt of South China显示文摘 | Yan Danping Zhang Bing Zhou Meifu | 2009 | Journal of Structural Geology2009，31，2： | 1 |
| 15 | Spectroscopic properties and energy transfer of Eu 2+ /Tb 3+ co-doped high silica glass显示文摘 | Yinglong Shen Qiang Zhang Jimeng Cheng Qiuchun Sheng Shuang Liu Wentao Li W. Chewpraditkul Danping Chen | 2013 | Materials Letters2013，，： | 1 |
| 16 | Minor change in the length of carbon chain has a great influence on the antitumor effect of paclitaxel-fatty alcohol prodrug nanoassemblies:Small roles,big impacts显示文摘Prodrug-based nanoassembly emerges as a hopeful way for the efficient delivery of antitumor drugs,with carrier-free structure and ultra-high drug loading.Carbon chains are widely used to design self-assembling prodrugs.The impacts of the length of carbon chains on the self-assembly stability,drug delivery efficiency and antitumor effect of prodrugs have not been fully elucidated.Here,three paclitaxel prodrugs were synthesized by conjugating paclitaxel with octanol(C_(8)),decanol(C_(10))or dodecanol(C_(12))through disulfide bond.The three prodrugs could form homogeneous nanoparticles,with over 50%drug loading and redox dual-responsivity.Interestingly,the length extension of carbon chains ameliorates the self-assembly and the colloidal stability of prodrugs,thus improving the drug delivery efficiency.The optimal paclitaxel-dodecanol prodrug nanoassemblies exhibit better antitumor efficacy than Taxol and Abraxane.These findings are meaningful for the rational design of advanced nanomedicines in cancer therapy. | Xin Wang Lingxiao Li Danping Wang Shiyi Zuo Tian Liu Fudan Dong Xuanbo Zhang Zhonggui He Bingjun Sun Jin Sun | 2022 | Nano Research2022，15，4： | 1 |
| 17 | Ion-exchange polymers modified bacterial cellulose electrodes for the selective removal of nitrite ions from tail water of dyeing wastewater显示文摘Ion-exchange polymer and modified carbonization bacterial cellulose(CBC)electrodes were fabricated using varying amounts of cation-exchange polymers(glutaric acid(GA)and sulfosuccinic acid(SSA))and assembled within an asymmetric capacitive deionization unit(p-CDI).The performance of selective NO2-electro-adsorption was studied.The AC/CBCSSA group showed a better salt adsorption capacity(14.56 mg/g)and nitrite removal efficiency(71.01%)than the AC/CBC-GA(10.72 mg/g,47.83%)and AC/AC(4.81 mg/g,12.74%)groups.It was confirmed that the CBC-SSA/GA electrodes enhanced nitrite selectivity and increased the adsorption capacity,and the total amounts of adsorbed anions increased when the applied voltage was increased from 0.8 to 1.2 V,while the molar fraction of nitrate decreased.The competitive and preferential adsorption of anions was further investigated using different binary solutions of anions and occurred in the following sequence:NO2->SO42->NO3->F-≈Cl-.Furthermore,the p-CDI units were applied to remove nitrite in real wastewater samples,and the results showed that they had excellent reusability and application for use in dyeing wastewater treatment. | Danping Li Xun-an Ning Yiqian Yuan Yanxiang Hong Jianpei Zhang | 2020 | Journal of Environmental Sciences2020，32，5： | 1 |
| 18 | Bright red upconversion luminescence of thulium ion-doped GeS2-In2S3-CsI Glasses 显示文摘 | XU Yinsheng CHEN Danping ZHANG Qiang | 2009 | J Phys Chem C2009，113，22： | 1 |
| 19 | Combination Treatment With VELCADE and Low-Dose Tissue Plasminogen Activator Provides Potent Neuroprotection in Aged Rats After Embolic Focal Ischemia显示文摘 | Li Zhang Zheng Gang Zhang Ben Buller James Jiang Yanting Jiang Danping Zhao Xianshuang Liu Dan Morris Michael Chopp | 2010 | Stroke2010，，5： | 1 |
| 20 | Characterization and antioxidant activities of degraded polysaccharides from Poria cocos sclerotium显示文摘 | Jin Tang Jing Nie Danping Li Wenjun Zhu Shaopeng Zhang Fang Ma Qiao Sun Jia Song Yonglian Zheng Ping Chen | 2014 | Carbohydrate Polymers2014，，： | 1 |
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