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| 1 | 一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas. | Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P | 2014 | 中华神经外科疾病研究杂志2014，13，5： | 6 |
| 2 | Acute ischaemic stroke interventions: large vessel occlusion and beyond显示文摘Care for acute ischaemic stroke is one of the most rapidly evolving fields due to the robust outcomes achieved by mechanical thrombectomy.Large vessel occlusion(LVO)accounts for up to 38%of acute ischaemic stroke and comes with devastating outcomes for patients,families and society in the pre-intervention era.A paradigm shift and a breakthrough brought mechanical thrombectomy back into the spotlight for acute ischaemic stroke;this was because five randomised controlled trials from several countries concluded that mechanical thrombectomy for acute stroke offered overwhelming benefits.This review article will present a comprehensive overview of LVO management,techniques and devices used,and the future of stroke therapy.In addition,we review our institution experience of mechanical thrombectomy for posterior and distal circulation occlusion. | Ahmad Sweid Batoul Hammoud Sunidhi Ramesh Daniella Wong Tyler D Alexander Joshua Harrison Weinberg Maureen Deprince Jaime Dougherty Dimitri Jean-Mickael Maamari Stavropoula Tjoumakaris Hekmat Zarzour Michael R Gooch Nabeel Herial Victor Romo David M Hasan Robert H Rosenwasser Pascal Jabbour | 2020 | Stroke & Vascular Neurology2020，5，1： | 2 |
| 3 | MicroRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival显示文摘 | Rossi S Shimizu M Barbarotto E Nicoloso MS Dimitri F Sampath D | | 0，，： | 1 |
| 4 | Water sorption isotherms and glass transition temperature of spray dried tomato pulp显示文摘 | Goula A M Karapantsios T D Achilias Dimitris S | 2008 | Journal of Food Engineering2008，85，8： | 1 |
| 5 | Oxidative stress as a common mediator for apoptosis induced-cardiac damage in diabetic rats显示文摘 | Mohammad M D Dimitri P M Mohamed A H | 2008 | Open Cardiovascular Med2008，2，： | 1 |
| 6 | Ex- pression of ectonucleotidase CD39 by Foxp3 + Treg cells : Hydrolysis of extracellular ATP and immunesup- pression 显示文摘 | Borsellino G Kleinewietfeld M Dimitri D | 2007 | Blood2007，110，4： | 1 |
| 7 | Fluorinated amphiphilic polymers and their blends for fouling- release applications: the benefits of a triblock eopolymer sur- face显示文摘 | SUNDARAM H S CHO Y DIMITRIOU M D | 2011 | Appl Mater Interfaces2011，3，： | 1 |
| 8 | Water sorption isotherms and glass transition temperature of spray dried tomato pulp显示文摘 | Athanasia M Goula Thodoris D Karapantsios Dimitris S Achilias | 2008 | Journal of Food Engineering2008，85，1： | 1 |
| 9 | Carboxylate clays: a model study for polypropylene/clay nanocomposites 显示文摘 | Dimitri D J Rousseaux M S Pierre G | 2010 | Polymer Degradation and Stability2010，95，： | 1 |
| 10 | Market risk model selection and medium-term risk with limited data: application to ocean tanker freight mar- kets显示文摘 | KAVUSSANOS M G DIMITRIS N D | 2011 | Int Rev of Financial Anal2011，20，5： | 1 |
| 11 | CD40 on salivary gland epithelial cells:high constitutive expression by cultured cells from Sjogren's syndrome patients indicating their intrinsic activation显示文摘 | Dimitriou I D Kapsogeorgou E K Moutsopoulos H M | 2002 | Clin Exp Immunol2002，127，2： | 1 |
| 12 | Diamond,former coesite and supersilicic garnet in metasedimentary rocks from the Greek Rhodope:a new ultrahigh-pressure metamorphic province established显示文摘 | EVRIPIDIS D M DIMITRIS K K | 2001 | Earth and Planetary Science Letters2001，192，： | 1 |
| 13 | Urinary Tract Infections显示文摘 | Dimitri M D James R J | 2008 | Prim Care Clin Office Pract2008，35，： | 1 |
| 14 | CD49 dprovides access- to untouched human Foxp3 * Treg free of contaminating effector cells 显示文摘 | Kleinewietfeld M Starke M DiMitri D et at | 2009 | Blood2009，113，28： | 1 |
| 15 | Robust design simu- lation:a probabilistic approach to multidisciplinary design 显示文摘 | Dimitri N M Oliver B Daniel A D | 1999 | Journal of Aircraft1999，36，1： | 1 |
| 16 | Arsenic and lead release from fly ash stabilized/solidified soils under modified semi-dynamic leaching conditions显示文摘 | DEOK H M DIMITRIS D | 2007 | Joumal of Hazardous Materials2007，141，： | 1 |
| 17 | Complement C5a receptor is essential for the optimal generation of antiviral CD8 + T cell responses显示文摘 | Kim A H Dimitriou I D Holland M C | 2004 | J Immunol2004，173，4： | 1 |
| 18 | Numericalsimulation of dynamic soil-structure interaction inshaking table testing显示文摘 | DIMITRIS P MATT D DAVID M W | 2008 | Soil Dynamics and EarthquakeEngineering2008，28，6： | 1 |
| 19 | An analysis of three-phase rectifiers with near- sinusoidal input currents显示文摘 | Dimitrie Alcxa Adriana Sirbu Dobrea D M | 2004 | IEEE Transactions on Industrial Electronics2004，51，4： | 1 |
| 20 | Study of oncogenic transformation in ex vivo expanded mesenchymal cells, from paediatric bone marrow显示文摘 | Choumerianou D M Dimitriou H Perdikogianni C | 2008 | Cell Prolif2008，41，6： | 1 |
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