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| 1 | Mycophenolate mofetil for drug-induced vanishing bile duct syndrome显示文摘Amoxicillin/clavulanate is associated with liver injury, mostly of a cholestatic pattern. While outcomes are usually benign, progression to cirrhosis and death has been reported. The role of immunosuppressive therapy for patients with a protracted course is unclear. We report the case of an elderly patient who developed prolonged cholestasis secondary to amoxicillin/clavulanate. Vanishing bile duct syndrome was confirmed by sequential liver biopsies. The patient responded to prednisone treatment, but could not be weaned off corticosteroids, even when azathioprine was added. Complete withdrawal of both prednisone and azathioprine was possible by using mycophenolate mofetil, an inosine monophosphate dehydrogenase inhibitor. Sustained remission has been maintained for more than 3 years with low-dose mycophenolate mofetil. | S Simona Jakab A Brian West Dennis M Meighan Robert S Brown Jr William B Hale | 2007 | World Journal of Gastroenterology2007，13，45： | 8 |
| 2 | Advancing research diagnostic criteria for Alzheimer’s disease: the IWG-2 criteria显示文摘 | Bruno Dubois Howard H Feldman Claudia Jacova Harald Hampel José Luis Molinuevo Kaj Blennow Steven T DeKosky Serge Gauthier Dennis Selkoe Randall Bateman Stefano Cappa Sebastian Crutch Sebastiaan Engelborghs Giovanni B Frisoni Nick C Fox Douglas Galasko Ma | 2014 | Lancet Neurology2014，，6： | 7 |
| 3 | New hope for hepatitis C virus:Summary of global epidemiologic changes and novel innovations over 20 years显示文摘Hepatitis C virus(HCV)is a global health concern associated with significant morbidity and mortality.Before the approval of second-generation direct-acting antiviral agents(DAAs),interferon therapy and liver transplantation constituted the mainstay of treatment.The introduction of well-tolerated oral DAAs in late 2013 has revolutionized HCV management with over 95%cure rates.The predominance of HCV-related liver transplantations has declined following the widespread approval of DAAs.Despite the unparallel efficacy observed among these novel therapies,pharmaceutical costs continue to limit equitable access to healthcare and likely contribute to the differential HCV infection rates observed globally.To reduce the burden of disease worldwide,essential agenda items for all countries must include the prioritization of integrated care models and access to DAAs therapies.Through transparent negotiations with the pharmaceutical industry,the consideration for compassionate release of medications to promote equitable division of care is paramount.Here we provide a literature review of HCV,changes in epidemiologic trends,access issues for current therapies,and global inequities in disease burden. | Brittany B Dennis Leen Naji Yasmin Jajarmi Aijaz Ahmed Donghee Kim | 2021 | World Journal of Gastroenterology2021，27，29： | 4 |
| 4 | Not interferon, but interleukin‐6 controls early gene expression in hepatitis B virus infection显示文摘 | Marianna H?sel Maria Quasdorff Katja Wiegmann Dennis Webb Uta Zedler Mathias Broxtermann Raindy Tedjokusumo Knud Esser Silke Arzberger Carsten J. Kirschning Anja Langenkamp Christine Falk Hildegard Büning Stefan Rose‐John Ulrike Protzer | 2009 | Hepatology2009，，6： | 3 |
| 5 | Synthesis of alkyl and aryl phosplaazene high polymers显示文摘 | Harry R Allcock Dennis B Patterson Thomas L Evans | 1977 | J Am Chem Soc1977，99，18： | 1 |
| 6 | Assessing the Eddy Covariance Technique for EvaluatingCaborn Dioxide Exchange Rates of Ecosystems:past,present and fu-ture显示文摘 | DENNIS B | 2003 | Global Change Biology2003，9，： | 1 |
| 7 | Effects of permeabi-lizers on antimicrobial susceptibility of Stenotroph-omonas maltophilia and Acinetobacter spp显示文摘 | Denny B West P Panigrahi D | | 0，，01： | 1 |
| 8 | Kinematics of the patellofemoral joint in total knee arthroplasty显示文摘 | Stiehl J B Komistek R D Dennis D A | 2001 | Journal of Arthroplasty2001，16，6： | 1 |
| 9 | FLUXNET:A New Tool to Study theTemporal and Spatial Variability of Ecosystem-scale Carbon Dio-xide,Water Vapor,and Energy Flux Densities显示文摘 | DENNIS B Eva F Gu L H | 2001 | Bulletin of the Amer-ican Meteorological Society2001，82，11： | 1 |
| 10 | The agreement between cervical abnormalities identified by cytology and detection of highrisk types of human papillomavirus显示文摘 | Allan B R Marais D I Denny L | 2006 | S Afr Med J2006，96，11： | 1 |
| 11 | Understanding the Fac-tors Influencing the Value of Person - to - Person Knowledge Sharing显示文摘 | BROWN S A DENNIS A R GANT D B | 2006 | System Sciences2006，1，7： | 1 |
| 12 | The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain显示文摘 | Pearson R B Dennis P B Han J W | 1995 | EMBO J1995，14，21： | 1 |
| 13 | Experience-dependent recovery of vision following chronic deprivation amblyopia 显示文摘 | He HY Ray B Dennis K Quinlan EM | 2007 | Nat Neurosci2007，10，9： | 1 |
| 14 | Deposition and redistribution of fungicides applied by air and chemigation for control of late blight in commercial potato显示文摘 | BRAD GEARY PHILIP B HAMM DENNIS A JOHNSON | 2008 | Americal Journal of Patato to Research2008，81，5： | 1 |
| 15 | Gamma-ray, neutron, and hard X-ray studies and requirements for a high-energy solar physics facility显示文摘 | Dennis B R | 1988 | Sol Phys1988，118，： | 1 |
| 16 | Hyperbilirubinemia in the term newbom显示文摘 | Porter M Dennis B | 2002 | Am Fam Physician2002，65，： | 1 |
| 17 | Hetero-arrays of Porphyrins and Phthalocyanines显示文摘 | Lo P C Leng X B Dennis K P N | 2007 | Coord Chem Rev2007，251，1720： | 1 |
| 18 | Biofiltration as an odour abatement strategy显示文摘 | John B | 2000 | Biochemical Engineering Journal2000，5，： | 1 |
| 19 | Phosphorylation and activation of p70s6k by PDK1显示文摘 | Pullen N Dennis P B Andjelkovic M | 1998 | Science1998，279，5351： | 1 |
| 20 | AutoantIb0dies to GPI in rheumatoid arthritis;linkage between an animal model and human disease显示文摘 | Monica S Dennis R B Henrik J D | 2001 | Nat Immunol2001，2，1： | 1 |
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