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| 1 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 2 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 3 | Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study显示文摘 | Julia Granerod Helen E Ambrose Nicholas WS Davies Jonathan P Clewley Amanda L Walsh Dilys Morgan Richard Cunningham Mark Zuckerman Ken J Mutton Tom Solomon Katherine N Ward Michael PT Lunn Sarosh R Irani Angela Vincent David WG Brown Natasha S Crowcroft | 2010 | The Lancet Infectious Diseases2010，，12： | 2 |
| 4 | Incidental non-benign gallbladder histopathology after cholecystectomy in an United Kingdom population: Need for routine histological analysis?显示文摘AIM To analyse the range of histopathology detected in the largest published United Kingdom series of cholecystectomy specimens and to evaluate the rational for selective histopathological analysis.METHODS Incidental gallbladder malignancy is rare in the United Kingdom with recent literature supporting selective histological assessment of gallbladders after routine cholecystectomy.All cholecystectomy gallbladder specimens examined by the histopathology department at our hospital during a five year period between March 2008 and March 2013 were retrospectively analysed.Further data was collected on all specimens demonstrating carcinoma,dysplasia and polypoid growths.RESULTS The study included 4027 patients.The majority(97%) of specimens exhibited gallstone or cholecystitis related disease.Polyps were demonstrated in 44(1.09%),the majority of which were cholesterol based(41/44).Dysplasia,ranging from low to multifocal high-grade was demonstrated in 55(1.37%).Incidental primary gallbladder adenocarcinoma was detected in 6 specimens(0.15%,5 female and 1 male),and a single gallbladder revealed carcinoma in situ(0.02%).This large single centre study demonstrated a full range of gallbladder disease from cholecystectomy specimens,including more than 1% neoplastic histology and two cases of macroscopically occult gallbladder malignancies.CONCLUSION Routine histological evaluation of all elective and emergency cholecystectomies is justified in a United Kingdom population as selective analysis has potential to miss potentially curable life threatening pathology. | Krashna Patel Khaled Dajani Satheesh Iype Nikolaos A Chatzizacharias Saranya Vickramarajah Susan Davies Rebecca Brais Siong S Liau Simon Harper Asif Jah Raaj K Praseedom Emmanuel L Huguet | 2016 | World Journal of Gastrointestinal Surgery2016，8，10： | 2 |
| 5 | Effective interventions for lifestyle change after myocardial infarction or coronary artery revascularization显示文摘 | COBB S L BROWN D J DAVIS L L | 2006 | J Am Acad Nurs Pract2006，18，1： | 1 |
| 6 | Rainbow trout has two genes for growth hormone显示文摘 | Agellon L B Davies S L Lin C M | 1988 | Mol Rep Develop1988，1，： | 1 |
| 7 | Evaluation of genetic variation in a domestic population of Penaeus qannamei Boone: a comparison with three natural populations 显示文摘 | Sunden S L F Davis S K | 1991 | Aquaculture1991，97，： | 1 |
| 8 | W4:Real-time surveillance of people and their activities 显示文摘 | HARITAOGLU I HARWOOD D DAVIS L S | 2000 | IEEE Transactions on Pattern Analysis and Machine Intelligence2000，22，8： | 1 |
| 9 | Clinical review 92: Phytoestrogens 显示文摘 | MURKIES A L WILCOX G DAVIS S R | 1998 | J Clin Endocrinol Metab1998，83，2： | 1 |
| 10 | W4:real-time surveillance of people and their activities显示文摘 | Haritaoglu I Harwood D Davis L S | 2000 | IEEE Transactions on Pattern Analysis and Machine Intelligence2000，22，8： | 1 |
| 11 | Asurvey of edge detection techaniques显示文摘 | Davis L S | 1975 | Proceedings of CSIP1975，4，： | 1 |
| 12 | Model-based object pose in 25 lines of code显示文摘 | Dementhon D F Davis L S | 1995 | International Journal of Computer Vision1995，15，12： | 1 |
| 13 | Radiofrequency energy tissue ablation for the treatment of nasal obstruction secondary to turbinate hypertrophy显示文摘 | Davis S Utley M D Richard L | 1999 | Laryngoscope1999，109，： | 1 |
| 14 | Deciphering the biology of My cobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole S T Brosch R Parkhill J Gamier T Churcher C Harris D Gordon S V Eiglmeier K Gas S Barry C E Tekaia F Badcock K Basham D Brown D Chillingworth T Cormor R Davies R Devlin K FeltweU T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Kroghs A McLean J Moule S Murphy L Oliver K Osborne J Quail M A Rafandream M A Rogers J Rutter S Seeger K Skelton J Squaraes R Squares S Sulston J E Taylo K Whitehead S Barrell B G | 1998 | Nature1998，393，： | 1 |
| 15 | An assessment of support vector machines for land cover classification 显示文摘 | HUANG C DAVIS L S TOWNSHEND J R G | 2002 | International Journal of Remote Sensing2002，23，4： | 1 |
| 16 | W4 : Real-Time Surveillance of People and Their Activities显示文摘 | Haritaoglu I Harwood D Davis L S | 2000 | IEEE Trans on Pattern Analysis and Machine Intelligence2000，22，8： | 1 |
| 17 | The Addition of Halogenocarbons to Alkenes in the Presence of and Related Complexes 显示文摘 | DAVIS R DURRANT J L A KHAZAL N M S | 1990 | J Organomet Chem1990，386，： | 1 |
| 18 | Environmental factors influencing heat stress in feedlot cattle显示文摘 | Mader T L Davis M S Brown-Brandl T | 2006 | Journal of Animal Science2006，84，3： | 1 |
| 19 | Detection of independent motion using directional motion estimation显示文摘 | Fejes S Davis L | | 0，，02： | 1 |
| 20 | Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression显示文摘 | Paoloni M Davis S Lana S Withrow S Sangiorgi L Picci P Hewitt S Triche T Meltzer P Khanna C | | 0，，： | 1 |
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