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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | 如何设计高质量针刺临床研究:基于证据的专家共识显示文摘本针刺随机对照试验(Randomised controlled trials, RCT)专家共识是基于目前针刺试验面临的最普遍、最关键问题,由临床医生、研究人员、从事针灸和外科的临床试验专家、统计专家、临床流行病学和方法学专家以及患者组成的国际临床研究小组联合制订。该共识将有助于临床试验资助者、注册者以及期刊编辑等评估针刺RCT方案及研究结果的相关性、重要性和质量。 | 张誉清 焦睿珉 Claudia M Witt 劳力行 刘建平 Lehana Thabane Karen J Sherman Mike Cummings Dawn P Richards Eun-Kyung Anna Kim Tae-Hun Kim Myeong Soo Lee Michael E Wechsler Benno Brinkhaus Jun J Mao Caroline A Smith 岗卫娟 刘保延 刘志顺 刘岩 郑晖 吴佳霓 AloBSO Carrasco-Labra Mohit Bhandari Philip J Devereaux 景向红 Gordon Guyatt | 2022 | 英国医学杂志中文版2022，25，6： | 7 |
| 3 | Calculation of viscous EHL traction for squalane using molecular simulation and rheometry显示文摘 | Bair S McCabe C Cummings P T | 2002 | Tribology Letters2002，13，4： | 1 |
| 4 | Dis-tribution Functions of a Simple Fluid under Shear:LowShear Rates显示文摘 | Kalyuzhnyi Y V Cui S T Cummings P T | 1999 | Phys Rev E1999，60，2： | 1 |
| 5 | The current and future applications of microorganism in the bioremediation of cyanide contamination 显示文摘 | BAXTER J CUMMINGS S P | 2006 | Antonie van Leeuwenhoek2006，90，1： | 1 |
| 6 | Size-fractionated nitrogen uptake and carbon fixation during a developing coccolithophore bloom in the North Sea during June 1999显示文摘 | Malcolm E Woodward S Robinson C Cummings D G Tarran G A Joint Ⅰ | 2002 | Deep-Sea Research Ⅱ2002，49，15： | 1 |
| 7 | C60 binds to and deforms nucleotides显示文摘 | Zhao X Striolo A Cummings P | 2005 | Biophys2005，89，6： | 1 |
| 8 | Process Optimiza- tion Via Simulated Annealing: Application to Network Design 显示文摘 | Dolan W B Cummings P T LeVan M D | 1989 | AIChEJ1989，35，5： | 1 |
| 9 | A high-efficiency Cre/ loxP-based system for construction of adenov iral vector显示文摘 | Ng P Parks RJ Cummings DT | 1999 | Hum Gene Ther1999，10，16： | 1 |
| 10 | Charging properties of cassiterite (a-Sn02) surfaces in NaC1 and RbC1 ionic media显示文摘 | ROSENQVIST J MACHESKY M L VLCEK L CUMMING P T WESOLOWSKI D J | 2009 | Langmuir2009，2，10： | 1 |
| 11 | Validation of the NPI-Q,a brief clinical form of the neuropsychiatric inventory显示文摘 | Kaufer D Cummings JL Ketchel P | 2000 | J Neuropsychiatry Clin Neursci2000，12，9： | 1 |
| 12 | Algorithmic Efficiency of Simulated Annealing for Heat Exchanger Network Design显示文摘 | Dolan W B Cummings P T LeVan M D | 1990 | ComputChemEng1990，14，10： | 1 |
| 13 | Refractive associations with cataract: the Blue Mountains Eye Study显示文摘 | Lim R Mitchell P Cumming RG | 1999 | Invest Ophthalmol Vis Sci1999，40，12： | 1 |
| 14 | Pulmonary-vein isolation for atrial fibrillation in patients with heart failure 显示文摘 | Khan MN Ja'fs P Cummings J | 2008 | N Engl J Med2008，359，17： | 1 |
| 15 | Migrating luteinizing hormone-releasing hormone (LHRH) neurons and processes are associated with a substrate that expresses S100显示文摘 | Brunjes P C | 1995 | Brain Res Dev Brain Res1995，88，： | 1 |
| 16 | Effects of nicotine and chlorisondamine on cerebral glucose utilization in immobilized and freely-moving rats显示文摘 | Marenco T Bernstein S Cumming P | 2000 | Br J Pharmacol2000，129，1： | 1 |
| 17 | Oral glucose loading acutely attenuates endothelium -dependent vasodilation in healthy adults without diabetes: an effect prevented by vitamins C and E显示文摘 | TITLE L M CUMMINGS P M GIDDENS K | 2000 | J Am Coil Cradiol2000，36，7： | 1 |
| 18 | DNA sequence variation in the ribosomal internal transcribed spacer region of freshwater Cladophora species (Chlorophyta) 显示文摘 | Marks J C Cummings M P | 1996 | Journal of Phycology1996，32，： | 1 |
| 19 | Fabrication of 3 nm wires using 100 keV electron beam lithography and poly(methyl methacrylate)resit显示文摘 | Thoms S Beaumont S P | 1996 | Appl Phys Lett1996，68，： | 1 |
| 20 | Increased pulmonary vascular filtration pressure does not alter lung liquid secretion in fetal sheep显示文摘 | CARLTON D P CUMMINGS J J POULAIN F R | 1992 | Appl Physiol1992，72，： | 1 |
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