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| 1 | Stem cell therapy in the management of shoulder rotator cuff disorders显示文摘Rotator cuff tears are frequent shoulder problems that are usually dealt with surgical repair. Despite improved surgical techniques, the tendon-to-bone healing rate is unsatisfactory due to difficulties in restoring the delicate transitional tissue between bone and tendon. It is essential to understand the molecular mechanisms that determine this failure. The study of the molecular environment during embryogenesis and during normal healing after injury is key in devising strategies to get a successful repair. Mesenchymal stem cells(MSC) can differentiate into different mesodermal tissues and have a strong paracrine, anti-inflammatory, immunoregulatory and angiogenic potential. Stem cell therapy is thus a potentially effective therapy to enhance rotator cuff healing. Promising results have been reported with the use of autologous MSC of different origins in animal studies: they have shown to have better healing properties, increasing the amount of fibrocartilage formation and improving the orientation of fibrocartilage fibers with less immunologic response and reduced lymphocyte infiltration. All these changes lead to an increase in biomechanical strength. However, animal research is still inconclusive and more experimental studies are needed before human application. Future directions include expanded stem cell therapy in combination with growth factors or different scaffolds as well as new stem cell types and gene therapy. | Maria Valencia Mora Miguel A Ruiz Ibán Jorge Díaz Heredia Raul Barco Laakso Ricardo Cuéllar Mariano García Arranz | 2015 | World Journal of Stem Cells2015,7,4: | 6 |
| 2 | Prevalence of asymptomatic malaria parasitaemia显示文摘Objective:To evaluate factors associated with prevalence of malaria parasitaemia at first antenatal care visit.Methods:The study was conducted at the University of Calabar Teaching Hospital from 1st June,2007 to 31st July,2007.A structured questionnaire was administered to a total of 545 pregnant women that were recruited in this study after obtaining informed consent and two slides of thin and thick films were prepared for each participant.Results:Five hundred and twenty(95.4%) out of the 545 participants suffered from malaria parasitaemia,the rest 4.6%of those who had no parasitaemia had experienced symptomatic malaria before and were treated in private hospitals prior to their recruitment into the study.All participants(100%) who did not have antimalarials had parasitaemia compared with 91.1%among those that had antimalarials.The proportion of moderate to severe parasitaemia was also significantly higher among the former.Besides,the difference in parasitaemia between primigravidae and multigravidae was statistically significant(P=0.000) too. Among the methods used for vector control,only insecticide treated nets(ITNS) was associated with significant reduction in the level of parasitaemia(RR=0.83).Conclusion:Malaria parasitaemia at first booking is significandy higher in primigravidae and women who have no anti-malaria treatment. The use of safe and effective antimalarial treatment along with ITNs will significandy reduce the level of parasitaemia in pregnant women. | Agan TU Ekabua JE Iklaki CU Oyo-Ita A Ibanga I | 2010 | Asian Pacific Journal of Tropical Medicine2010,3,1: | 2 |
| 3 | Получение изотоna ^13C метолом ректификации окиси рглерола 显示文摘 | ACAMUAHU П Я KAMUCKUCЗЕВU B A ОЗUАΩCUЛU Е Л | 1968 | Isotopenpraxis1968,4,7: | 1 |
| 4 | Comparison of the incidences of left ventricular hypertrophy,left ventricular diastolic dysfunction,and arrhythmia between patients with dipper and non-dipper hypertension显示文摘 | Ersoylu ZD Tu(g)cu A Yildirimtürk O | 2008 | Turk Kardiyol Dern Ars2008,36,5: | 1 |
| 5 | Ultrasound-guided radiofrequency ablation:a new treatment option after failure to stop severe acute upper gastrointestinal tumor bleeding using endoscopic techniques显示文摘 | STANG A VON SEYDWITZ CU CELBCIOGLU S | 2004 | Endoscopy2004,36,6: | 1 |
| 6 | Influence of DAOA gene variants on antipsychotic response after switch to aripiprazole显示文摘 | Pae CU Chiesa A Serretti A | 2010 | Psychiatry Res2010,178,2: | 1 |
| 7 | The prevention of pain from injection of rocuronium by ondansetron,lidocaine,tramadol,and fentanyl显示文摘 | Memi D Turan A Karamanlio lu B Süt N Pamuk Cu Z | 2002 | Anesth Analg2002,94,: | 1 |
| 8 | N-acetylcysteine inhibits TNF-alpha, sTNFR, and TGF-betal release by alveolar macrophages in idiopathic pulmonary fibrosis in vitro 显示文摘 | Cu A Ye Q Sarria R | 2009 | Sarcoidosis Vase Diffuse Lung Dis2009,26,2: | 1 |
| 9 | Cyclic AMP relaxation of rat aortic smooth muscle is mediated in part by decrease of depletion of intracellular Ca2 + stores and inhibition of capacitative calcium entry显示文摘 | Cuí as A Elíes J Orallo F | | 0,,1: | 1 |
| 10 | Development of phosphorylated glucomannan-coatod chitosan nanoparticles as nanocarriers for protein delivery显示文摘 | Cu(n)a M Alonso-Sandel M Remu(n)án-López C Pivel JP Alonso-Lebrero JL Alonso MJ | | 0,,9: | 1 |
| 11 | B-cell receptor signaling as a driver of lymphoma development and evolution显示文摘 | Niemann CU Wiestner A | 2013 | Semin Cancer Biol2013,23,: | 1 |
| 12 | Electrocardiographic applications of lead aVR显示文摘 | Williamson K Mattu A Plautz CU | 2006 | Am J Emerg Med2006,24,7: | 1 |
| 13 | Effectiveness of a multidimensional approach for prevention of ventilator-associated pneumonia in adult intensive care units from 14 developing countries of four continents: Findings of the International Nosocomial Infection Control Consortium*显示文摘 | Victor D. Rosenthal Camilla Rodrigues Carlos álvarez-Moreno Naoufel Madani Zan Mitrev Guxiang Ye Reinaldo Salomao Fatma Ulger Humberto Guanche-Garcell Souha S. Kanj Luis E. Cuéllar Francisco Higuera Trudell Mapp Rosalía Fernández-Hidalgo | 2012 | Critical Care Medicine2012,,: | 1 |
| 14 | Modeling and Experimental Assessment of Suspension Dynamics of a Horizontal-Axis Washing Machine 显示文摘 | Tu(^g)cu A K Kiray B | 1998 | Journal of Vibration and Acoustics Transactions of the ASE1998,120,4: | 1 |
| 15 | The catheter to vein ratio and rates of symptomatic venous thromboembolism in patients with aperipherally inserted central catheter(PICC):A prospective cohort study显示文摘 | Shar p R Cu m mings M Fielder A | 2015 | Int J Nurs Stud2015,52,3: | 1 |
| 16 | Autoradiographic localization of specific kainic acid binding sites in pigeon and rat cerebellum显示文摘 | Henke H Beaudet A Cuénod M | 1981 | Brain Res1981,219,1: | 1 |
| 17 | Heat-shock protein-70 genes and response to antidepressants in major depression显示文摘 | Pae CU Mandelli L Serretti A | 2007 | Prog Neuropsychopharmacol Biol Psychiatry2007,31,5: | 1 |
| 18 | X-linked retinoschisis:a clinical and molecular genetic review显示文摘 | Tanlri A Vrabee TR Cu Unjieng A | 2004 | Surv Ophthalmol2004,49,20: | 1 |
| 19 | Advances in chimeric antigen receptor immunotherapy for neurohlastoma 显示文摘 | Heczey A Louis CU | 2013 | Discov Med2013,16,90: | 1 |
| 20 | C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon 显示文摘 | Choe CU Schulze-Bahr E Neu A | 2006 | Hum Mol Cenet2006,15,19: | 1 |