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| 1 | Risk factors for cervical lymph node metastasis in papillary thyroid microcarcinoma: a study of 1,587 patients显示文摘Objective: The purposes of this study were to identify risk factors for cervical lymph node metastasis and to examine the association between BRAF^(V600E) status and clinical features in papillary thyroid microcarcinoma(PTMC).Methods: A total of 1,587 patients with PTMC, treated in Tianjin Medical University Cancer Institute and Hospital from January2011 to March 2013, underwent retrospective analysis. We reviewed and analyzed factors including clinical results, pathology records, ultrasound results, and BRAF^(V600E) status.Results: Multivariate logistic regression analyses demonstrated that gender(male) [odds ratio(OR) = 1.845, P = 0.000], age(< 45 years)(OR = 1.606, P = 0.000), tumor size(> 6 mm)(OR = 2.137, P = 0.000), bilateralism(OR = 2.011, P = 0.000) and extrathyroidal extension(OR = 1.555, P = 0.001) served as independent predictors of central lymph node metastasis(CLNM).Moreover, CLNM(OR = 29.354, P = 0.000) served as an independent predictor of lateral lymph node metastasis(LLNM). Among patients with a solitary primary tumor, those with tumor location in the lower third of the thyroid lobe or the isthmus were more likely to experience CLNM(P < 0.05). Univariate analyses indicated that CLNM, LLNM, extrathyroidal extension, and multifocality were not significantly associated with BRAF^(V600E) mutation.Conclusions: The present study suggested that prophylactic neck dissection of the central compartment should be considered in patients with PTMC, particularly in men with tumor size greater than 6 mm, age less than 45 years, extrathyroidal extension, and tumor bilaterality. Among patients with PTMC, BRAF^(V600E) mutation is not significantly associated with prognostic factors. For a better understanding of surgical management of PTMC and the risk factors, we recommend multicenter research and long-term follow-up. | Xiangqian Zheng Chen Peng Ming Gao Jingtai Zhi Xiukun Hou Jingzhu Zhao Xi Wei Jiadong Chi Dapeng Li Biyun Qian | 2019 | Cancer Biology & Medicine2019，16，1： | 54 |
| 2 | Dual-stage Optimal Iterative Learning Control for Nonlinear Non-affine Discrete-time Systems显示文摘根据沿着重复轴的一种新动态 linearization 技术,双阶段的最佳的反复的学习控制为非线性、非仿射的分离时间的系统被介绍。双阶段显示二个最佳的学习阶段分别地被设计反复地改进控制输入顺序和学习获得。主要特征是控制器设计和集中分析仅仅取决于动态系统的 I/O 数据。换句话说,没有知道系统的任何另外的知识,我们能容易选择控制参数。模拟学习沿着重复轴说明介绍方法的几何集中,在哪个马路的一个例子控制为它的内在的工程重要性是引人注目的交通反复的学习。 | CHI Rong-Hu HOU Zhong-Sheng | 2007 | 自动化学报2007，33，10： | 19 |
| 3 | Cropland redistribution to marginal lands undermines environmental sustainability显示文摘Cropland redistribution to marginal land has been reported worldwide;however,the resulting impacts on environmental sustainability have not been investigated sufficiently.Here we investigated the environmental impacts of cropland redistribution in China.As a result of urbanization-induced loss of high-quality croplands in south China(~8.5 t ha^(-1)),croplands expanded to marginal lands in northeast(~4.5 t ha^(-1)) and northwest China(~2.9 t ha^(-1)) during 1990-2015 to pursue food security.However,the reclamation in these low-yield and ecologically vulnerable zones considerably undermined local environmental sustainability,for example increasing wind erosion(+3.47%),irrigation water consumption(+34.42%),fertilizer use(+20.02%) and decreasing natural habitats(-3.11%).Forecasts show that further reclamation in marginal lands per current policies would exacerbate environmental costs by 2050.The future cropland security risk will be remarkably intensified because of the conflict between food production and environmental sustainability.Our research suggests that globally emerging reclamation of marginal lands should be restricted and crop yield boost should be encouraged for both food security and environmental benefits. | Wenhui Kuang Jiyuan Liu Hanqin Tian Hao Shi Jinwei Dong Changqing Song Xiaoyong Li Guoming Du Yali Hou Dengsheng Lu Wenfeng Chi Tao Pan Shuwen Zhang Rafiq Hamdi Zherui Yin Huimin Yan Changzhen Yan Shixin Wu Rendong Li Jiuchun Yang Yinyin Dou Wenbin Wu Liqiao Liang Bao Xiang Shiqi Yang | 2022 | National Science Review2022，9，1： | 13 |
| 4 | Prostate cancer in Asia:A collaborative report显示文摘The incidence of prostate cancer(PCa)within Asian population used to be much lower than in the Western population;however,in recent years the incidence and mortality rate of PCa in some Asian countries have grown rapidly.This collaborative report summarized the latest epidemiology information,risk factors,and racial differences in PCa diagnosis,current status and new trends in surgery management and novel agents for castration-resistant prostate cancer.We believe such information would be helpful in clinical decision making for urologists and oncologists,health-care ministries and medical researchers. | Rui Chen Shancheng Ren 无 Ming Kwong Yiu Ng Chi Fai Wai Sam Cheng Lap Hong Ian Seiji Naito Tadashi Matsuda Elijah Kehinde Ali Kural Jason Yichun Chiu Rainy Umbas Qiang Wei Xiaolei Shi Liqun Zhou Jian Huang Yiran Huang Liping Xie Lulin Ma Changjun Yin Danfeng Xu Kexin Xu Zhangqun Ye Chunxiao Liu Dingwei Ye Xin Gao Qiang Fu Jianquan Hou Jianlin Yuan Dalin He Tiejun Pan Qiang Ding Fengshuo Jin Benkang Shi Gongxian Wang Xiuheng Liu Dongwen Wang Zhoujun Shen Xiangbo Kong Wanhai Xu Yaoliang Deng Haibo Xia Alexa NCohen Xu Gao Chuanliang Xu Yinghao Sun | 2014 | Asian Journal of Urology2014，1，1： | 13 |
| 5 | A Model-free Periodic Adaptive Control for Freeway Traffic Density via Ramp Metering显示文摘 | CHI Rong-Hu HOU Zhong-Sheng | 2010 | 自动化学报2010，36，7： | 11 |
| 6 | A New Discrete-time Adaptive ILC for Nonlinear Systems with Time-varying Parametric Uncertainties显示文摘用在分离时间轴和反复的学习轴之间的类比,一条新分离时间的适应反复的学习控制(AILC ) 途径被开发与变化时间的参量的无常探讨非线性的系统的一个班。类似于适应控制,新 AILC 能合并一个设计算法,因此,学习获得能沿着学习的轴反复地被调节。当起始的状态是随机的,参考轨道是变化重复的时,新 AILC 能沿着反复的学习轴 asymptotically 在有限时间间隔上完成 pointwise 集中。 | CHI Rong-Hu SUI Shu-Lin HOU Zhong-Sheng | 2008 | 自动化学报2008，34，7： | 9 |
| 7 | Expression pattern of neural synaptic plasticity marker-Arc in different brain regions induced by conditioned drug withdrawal from acute morphine-dependent rats显示文摘 | Mu LI Yuan-yuan HOU Bin LU Jie CHEN Zhi-qiang CHI Jing-gen LIU | 2009 | Acta Pharmacologica Sinica2009，30，3： | 5 |
| 8 | Freeform OST-HMD system with large exit pupil diameter and vision correction capability显示文摘Compactness and light weight,large exit pupil diameter and distance,small distortion for virtual image,and see-through light paths are pivotal factors to achieve a better,wearable experience of optical see-through headmounted displays(OST-HMDs).In addition,light efficiency of the virtual image light path is an important factor for heat dissipation in HMD devices.This paper presents a new type of OST-HMD optical system that includes three wedge-shaped freeform prisms and two symmetric lenses.Based on a 0.71 in.microdisplay,an OST-HMD prototype with a diagonal field of view(FOV)of 45.3°,an F-number(F/#)of 1.8,an exit pupil size of 12 mm×8 mm,and an eye relief of 18 mm is demonstrated.The maximum value of distortion of the final system is 0.6%and 0.4%for virtual image and see-through light path,respectively.The overall dimension of the optical system per eye is no larger than 30 mm(width)×40 mm(height)×14 mm(thickness),and the weight of the optical module including lenses,holder,and microdisplay is 12.8 g.The light efficiency of the virtual image light path is up to 50%higher than those of other OST-HMD optical solutions. | DEWEN CHENG JIAXI DUAN HAILONG CHEN HE WANG DANYANG LI QIWEI WANG QICHAO HOU TONG YANG WEIHONG HOU DONGHUA WANG XIAOYU CHI BIN JIANG YONGTIAN WANG | 2022 | Photonics Research2022，10，1： | 5 |
| 9 | Study on the spectral response of Brassica Campestris L. leaf to the copper pollution显示文摘Brassica Campestis L. was cultivated in the soil at the laboratory. The red edge,the visual spectrum and the near-infrared spectrum of Brassica Campestis L. leaf were used to explore the spectral response of Brassica Campestis L. leaf to the copper stress. As the Cu content in the soil gets increased,the copper level in Brassica Campestris L. leaf would be increased,and the chlorophyll level in Brassica Campestris L. leaf would be decreased. As a result,the visual spectral reflectance (A1) of Brassica Campestris L. leaf is increased,and the blue-shift (moving towards the shorter waveband) degree (S) of the red edge (the ascending region of the re-flectivity at 680―740 nm) gets increased. However,the near-infrared spectral re-flectance (A2) decreases. With the correlation coefficient R2 more than 0.95,these parameters of A1,A2 and S can be perfectly used to simulate and predict the copper level in Brassica Campestris L. leaf. | LIU SuHong LIU XinHui HOU Juan CHI GuangYu CUI BaoShan | 2008 | Science China(Technological Sciences)2008，51，2： | 5 |
| 10 | The structure of erastin-bound xCT-4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis显示文摘Dear Editor,Ferroptosis is an iron-dependent,non-apoptotic form of regulated cell death characterized by an accumulation of lipid.derived reactive oxygen species(ROS).The small-molecule compo und erastin in duces ferroptosis via in hibiti ng the cystineglutamate antiporter system x_(c).which consists of two subunits,namely the light chain xCT and the heavy chain 4F2hc(encoded by the SLC7A11 and SLC3A2 genes,respectively).^(1-4) | Renhong Yan Enjun Xie Yaning Li Jin Li Yuanyuan Zhang Ximin Chi Xueping Hu Lei xu Tingjun Hou Brent R.Stockwell Junxia Min Qiang Zhou Fudi Wang | 2022 | Cell Research2022，32，7： | 4 |
| 11 | Study of thermo-fluidic characteristics for geometric-anisotropy Kagome truss-cored lattice显示文摘The aim of this paper is to provide a comprehensive comparison of the thermal insulation and heat transfer performance for Kagome truss-cored lattice along two perpendicular orientations OA and OB. Three test conditions are conducted under forced air convection for the titanium sandwich panel fabricated by 3 D printing technology. The thermo-fluidic characteristics are further explored by numerical simulation to reveal the underlying mechanisms of heat transfer enhancement.The results indicate that the orientation OB exhibits better thermal insulation than orientation OA under the identical temperature loading, while the latter outperforms the former by up to 20% higher overall heat transfer performance. In particular, the endwalls and lattice core in orientation OA achieve 9.7% and 22.5% higher area-averaged Nusselt number respectively than that in orientation OB for a given Reynolds number. The heat transfer superiority of orientation OA comes from the unique topology which induces the large scale spiral primary flows, facilitating the heat exchange between the cooling air and the surfaces of sandwich panel. However, the complex flow mixing leads to a maximum of 20% higher friction factor in orientation OA than that in orientation OB. | Chi HOU Guangmeng YANG Xiaopeng WAN Jie CHEN | 2019 | Chinese Journal of Aeronautics2019，32，7： | 3 |
| 12 | Neural Network State Learning Based Adaptive Terminal ILC for Tracking Iteration-varying Target Points显示文摘Terminal iterative learning control(TILC) is developed to reduce the error between system output and a fixed desired point at the terminal end of operation interval over iterations under strictly identical initial conditions. In this work, the initial states are not required to be identical further but can be varying from iteration to iteration. In addition, the desired terminal point is not fixed any more but is allowed to change run-to-run. Consequently, a new adaptive TILC is proposed with a neural network initial state learning mechanism to achieve the learning objective over iterations. The neural network is used to approximate the effect of iteration-varying initial states on the terminal output and the neural network weights are identified iteratively along the iteration axis.A dead-zone scheme is developed such that both learning and adaptation are performed only if the terminal tracking error is outside a designated error bound. It is shown that the proposed approach is able to track run-varying terminal desired points fast with a specified tracking accuracy beyond the initial state variance. | Yu Liu Rong-Hu Chi Zhong-Sheng Hou | 2015 | International Journal of Automation and computing2015，12，3： | 2 |
| 13 | Opti mal higher order learning adaptive control approach for a class of SISO nonlinear systems显示文摘In this paper,an optimal higher order learning adaptive control approach is developed for a class of SISO nonlinear systems.This design is model-free and depends directly on pseudo-partial-derivatives derived on-line from the input and output information of the system.A novel weighted one-step-ahead control criterion function is proposed for the control law.The convergence analysis shows that the proposed control law can guarantee the convergence under the assumption that the desired output is a set point.Simulation examples are provided for nonlinear systems to illustrate the better performance of the higher order learning adaptive control. | Ronghu CHI Zhongsheng HOU | 2005 | 控制理论与应用(英文版)2005，3，3： | 2 |
| 14 | A NEW NEURAL NETWORK-BASED ADAPTIVE ILC FOR NONLINEAR DISCRETE-TIME SYSTEMS WITH DEAD ZONE SCHEME显示文摘By introducing a dead-zone scheme,a new neural network based adaptive iterative learn-ing control (ILC) (NN-AILC) scheme is presented for nonlinear discrete-time systems,where the NNweights are time-varying.The most distinct contribution of the proposed NN-AILC is the relaxationof the identical conditions of initial state and reference trajectory,which are common requirementsin traditional ILC problems.Convergence analysis indicates that the tracking error converges to abounded ball,whose size is determined by the dead-zone nonlinearity.Computer simulations verify thetheoretical results. | Ronghu CHI Zhongsheng HOU | 2009 | Journal of Systems Science & Complexity2009，22，3： | 2 |
| 15 | Glutamate receptors in the dorsal hippocampus mediate the acquisition, but not the expression, of conditioned place aversion induced by acute morphine withdrawal in rats显示文摘 | Yuan-yuan HOU Yao LIU Shuo KANG Chuan YU Zhi-qiang CHI Jing-gen LIU | 2009 | Acta Pharmacologica Sinica2009，30，10： | 2 |
| 16 | Adaptive ILC for a class of discrete-time systems with iteration-varying trajectory and random initial condition显示文摘 | Ronghu Chi Zhongsheng Hou Jianxin Xu | 2008 | Automatica2008，，8： | 2 |
| 17 | ATP regulates the phosphorylation and degradation of myofibrillar proteins in ground ovine muscle显示文摘Phosphorylation post-translational modification plays an important role in postmortem muscle quality traits. Adenosine triphosphate(ATP) is an energy source and a key substrate of phosphorylation which provides the phosphatase groups to proteins in the presence of protein kinases. However, in postmortem muscle, the effects of ATP content on phosphorylation are poorly studied. The study investigated the effect of ATP on protein phosphorylation and degradation in postmortem ovine muscle. The ground muscle with/without additional ATP were treated/control groups and stored at 25 and 4℃, respectively. The ATP content led to different changes of p H value between the ATP-treated and control groups. The phosphorylation level of myofibrillar proteins was higher(P<0.05) in ATP-treated group compared to the control group at both temperatures, which suggested that ATP played a vital role in postmortem protein phosphorylation. A slower degradation rate of μ-calpain, desmin and troponin T was observed in the ATP-treated group which showed that there was a negative relationship between ATP level and the degradation of proteins. These observations clearly highlighted the role of ATP on the development of meat quality by regulating the phosphorylation and degradation of myofibrillar proteins in postmortem ovine muscle. | REN Chi HOU Cheng-li ZHANG De-quan LI Xin XIAO Xiong BAI Yu-qiang | 2021 | Journal of Integrative Agriculture2021，20，1： | 2 |
| 18 | Development of and Intelligen't CAE System for Auto-body Concept Design 显示文摘 | Hou W B Zhang H Z Chi R F | 2009 | Inter- national Journal of Automotive Technology2009，10，2： | 1 |
| 19 | Underwater Environment SDAP Method Using Multi Single-Beam Sonars显示文摘 | Zheping Yan Dongnan Chi Shuping Hou Yalin Zheng Zhiguang Feng | 2013 | Mathematical Problems in Engineering2013，，： | 1 |
| 20 | Low conversion-loss fourth subharmonic mixers incorporating CMRC for millimeter-wave applications 显示文摘 | Xue Quan Shum Kam Man Chan Chi Hou | 2003 | IEEE Transactions on Microwave Theory and Techniques2003，51，5： | 1 |
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