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9篇 您的检索式:作者名="Chetan Sharma"
    题名 作者 年代 出处 被引量
1Supernumerary testis: a case report and review of literature显示文摘Basant Kumar Chetan Sharma D.D. Sinha 2008Journal of Pediatric Surgery2008,,6:1
2Multicomponent domino process for the synthesis of some novel 5-(arylidene)-3-((1-aryl-1H-1,2,3-triazol-4-yl)methyl)-thiazolidine-2,4-diones using PEG-400 as an efficient reaction medium and their antimicrobial evaluation显示文摘A series of novel thiazolidinedione-triazole hybrids were synthesized by one pot reaction between thiazolidine-2.4-dione,substituted aryl aldehydes,piopargyl bromide and substituted aryl azides using piperidine,CuSO_4· 5H_2O and sodium ascorbate as catalysts in PEG-400 as a highly efficient and green media.These thiazolidinedione-triazole hybrids were subjected to in vitro antibacterial activity against four strains namely.Staphylococcus aureus.Bacillus subtilis,Escherichia coli,Pseudomonas aeruginosa and antifungal activity against two fungal strains namely,Aspergillus niger and Aspergillus flavus.Jayant Sindhu Harjinder Singh J.M.Khurana Chetan Sharma K.R.Aneja 2015Chinese Chemical Letters2015,26,1:1
3Critical care practice in India:Results of the intensive care unit need assessment survey(ININ2018)显示文摘BACKGROUND A diverse country like India may have variable intensive care units(ICUs)practices at state and city levels.AIM To gain insight into clinical services and processes of care in ICUs in India,this would help plan for potential educational and quality improvement interventions.METHODS The Indian ICU needs assessment research group of diverse-skilled individuals was formed.A pan-India survey'Indian National ICU Needs'assessment(ININ 2018-I)was designed on google forms and deployed from July 23rd-August 25th,2018.The survey was sent to select distribution lists of ICU providers from all 29 states and 7 union territories(UTs).In addition to emails and phone calls,social medial applications-WhatsApp™,Facebook™and LinkedIn™were used to remind and motivate providers.By completing and submitting the survey,providers gave their consent for research purposes.This study was deemed eligible for category-2 Institutional Review Board exempt status.RESULTS There were total 134 adult/adult-pediatrics ICU responses from 24(83%out of 29)states,and two(28%out of 7)UTs in 61 cities.They had median(IQR)16(10-25)beds and most,were mixed medical-surgical,111(83%),with 108(81%)being adult-only ICUs.Representative responders were young,median(IQR),38(32-44)years age and majority,n=108(81%)were males.The consultants were,n=101(75%).A total of 77(57%)reported to have 24 h in-house intensivist.A total of 68(51%)ICUs reported to have either 2:1 or 2≥:1 patient:nurse ratio.More than 80%of the ICUs were open,and mixed type.Protocols followed regularly by the ICUs included sepsis care,ventilator-associated pneumonia(83%each);nutrition(82%),deep vein thrombosis prophylaxis(87%),stress ulcer prophylaxis(88%)and glycemic control(92%).Digital infrastructure was found to be poor,with only 46%of the ICUs reporting high-speed internet availability.CONCLUSION In this large,national,semi-structured,need-assessment survey,the need for improved manpower including;in-house intensivists,and decreasing patient-tonurse ratios was evident.Sepsis was the most common diagnosis and quality and research initiatives to decrease sepsis mortality and ICU length of stay could be prioritized.Additionally,subsequent surveys can focus on digital infrastructure for standardized care and efficient resource utilization and enhancing compliance with existing protocols.Rahul Kashyap Kirtivardhan Vashistha Chetan Saini Taru Dutt Dileep Raman Vikas Bansal Harpreet Singh Geeta Bhandari Nagarajan Ramakrishnan Harshit Seth Divya Sharma Premkumar Seshadri Mradul Kumar Daga Mohan Gurjar Yash Javeri Salim Surani Joseph Varon 2020World Journal of Critical Care Medicine2020,9,2:1
4Chloroform vapour sensor based on copper/polyaniline nanocomposite显示文摘Satish Sharma Chetan Nirkhe Sushama Pethkar Anjali A. Athawale 2002Sensors & Actuators: B. Chemical2002,,1:1
5Antimicrobial potential of Terminalia chebula Retz. fruit extracts against ear pathogens显示文摘AIM: To evaluate the antimicrobial potential of Terminalia chebula(T. chebula) extracts against pathogens causing otitis externa and compare it with ear drops.METHODS: Four different extracts, methanol, ethanol,acetone and aqueous(hot and cold) extracts, from the T. chebula were tested for their antimicrobial activity through the agar well diffusion method and minimum inhibitory concentration(MIC)/minimum bactericidal concentration(MBC) values were determined through the macrodilution broth method against six different microorganism, five bacterial(one gram positive and four gram negative) and one yeast.RESULTS: Organic and aqueous fruit extracts displayed activity against all five tested bacterial ear pathogens with a maximum zone of inhibition of 31.6 mm against Staphylococcus aureus, followed by Acinetobacter sp.(24.6 mm), Pseudomonas aeruginosa(23.6 mm),Proteus mirabilis(21 mm) and Escherichia coli(19.3mm). Of the four solvents evaluated, acetonic fruit extract of T. chebula was found to be best. The MIC values ranged between 0.78 mg/m L and 50 mg/m L for the different bacterial ear pathogens and MBC values ranged between 1.56 mg/m L and 50 mg/m L. The acetonic fruit extract showed larger inhibition zones compared to the herbal ear drops, Kan pip with lowest MIC of 0.78 mg/m L and MBC of 1.56 mg/m L.CONCLUSION: Acetonic extract of T. chebula fruit may be used to treat otitis externa. However, more detailed studies, such as in vivo testing and pharmacokinetics properties, are needed to determine its therapeutic potential.Chetan Sharma Kamal R Aneja Ramkrashan Kasera Ashish Aneja 2012World Journal of Otorhinolaryngology2012,2,2:1
6Studies on water quality of Sutlej River around Ludhiana with reference to physicochemical parameters显示文摘Jindal R Sharma Chetan 2011Environmental Monitoring and Assessment2011,174,1234:1
7Hypervalent iodine(III) mediated synthesis of novel unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles as antibacterial and antifungal agents显示文摘Om Prakash Manoj Kumar Rajesh Kumar Chetan Sharma K.R. Aneja 2010European Journal of Medicinal Chemistry2010,,9:1
8One pot three component synthesis of spiro [indolo-3,10’-indeno[1,2-b]quinolin]-2,4,11’-triones as a new class of antifungal and antimicrobial agents显示文摘A simple and efficient three component procedure has been developed for the synthesis of highly substituted spiro[indolo-3,100-indeno[1,2-b]quinolin]-2,4,11'-triones by one pot three component condensation of enaminones, isatin and indane-1,3-dione in ethanol:water(1:1) in presence of ceric ammonium nitrate(CAN) as catalyst. This method provides several advantages such as lesser reaction time, high yield of products and operational simplicity. The antimicrobial activity of some of the compounds has been investigated against six microbial strains, some of the tested compounds showed good antimicrobial activity.Kalawati Meena Sudesh Kumari Jitender M.Khurana Amita Malik Chetan Sharma Harsh Panwar 2017Chinese Chemical Letters2017,28,1:0
9Climate change detection and attribution in the Ganga-Brahmaputra-Meghna river basins显示文摘Ganga-Brahmaputra-Meghna(GBM)river basin is the third-largest and one of the most populated river basins in the world.As climate change is affecting most of the hydrometeorological variables across the globe,this study investigated the existence of climate change signal in all four climatological seasons in the GBM river basin and assessed the contribution of anthropogenic activities,i.e.,Greenhouse Gases(GHGs)emission in the change.Significant decreasing trends in the monsoon and a small increase in pre-monsoon precipitation were observed.Negligible change was detected in post-monsoon and winter season precipitation.CMIP5 GCMs were used for climate change detection,change point estimation,and attribution studies.Support Vector Machine(SVM)regression method was adopted to downscale GCM variables at the local scale.Monte-Carlo simulation approach was used to detect changes in different seasons.The climate change‘signals’were detectable after the year 1980 using Signal to Noise ratio(SNR)method in the majority of central and north-western regions.The change point was detectable only in annual monsoon precipitation at the basin level.Attribution analysis indicated>50%contribution of anthropogenic activities(GHGs)to annual monsoon precipitation changes.So,there is high confidence that monsoon precipitation in GBM has significantly changed due to anthropogenic activities.Different mitigation and adaption measures are also suggested,which may be adopted to manage the growing demand and water availability in the basin.Chetan Sharma Anoop Kumar Shukla Yongqiang Zhang 2021Geoscience Frontiers2021,12,5:0
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