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| 1 | A cross-sectional study on compliance with topical glaucoma medication and its associated socioeconomic burden for a Chinese population显示文摘AIM: To estimate the overall drug compliance for local Chinese glaucoma patients on long-term topical treatment.METHODS: This was a retrospective cross-sectional study.Fifty-seven primary glaucoma patients from the subspecialty clinic of a publicly-funded tertiary care hospital in Hong Kong completed a questionnaire on compliance with topical glaucoma medication,attitude towards glaucoma and therapy and vision related quality of life.Noncompliance was defined as reporting missing more than or equal to 10% of the prescribed topical glaucoma medication during the 2wk immediately prior to the consultation.Relationships between noncompliance and demographics,attitude,disease and treatment status was studied.Cost was estimated with quality of life and direct medical cost involved with noncompliance.Multivariable logistic regression on noncompliance was performed on selected factors.RESULTS: Compliance was calculated as 75%(95% CI: 64%-87%) among 57 subjects(mean age 69 y,female 51%).No statistical significant relationship was established between noncompliance and any single factors or outcomes.Age(P=0.048) and forgetfulness(P=0.064) were found to be marginally significant predictive factors on noncompliance in multivariable logistic regression.Noncompliance might be related(P=0.130) to poorer self-rated vision-associated quality of life.The societal cost of noncompliance was estimated to be over 2510 life-years and US$ 3.7 million territory-wide.CONCLUSION: The compliance of Chinese glaucoma patients in Hong Kong is comparable to other parts in the world,and carries detrimental impacts on individual and societal levels.Age and forgetfulness are two possible independent predictors for noncompliance. | Man-Hin Lui Jason Chun Ho Lam Yi Lee Kwong Tak Siu Wong Pak Long Cheung Sherri Shun Yan Lai Pak Lun Yuen Wai Yiu Lam Ho Yan Chan Yiu Fai Wong Jimmy Shiu Ming Lai Kendrick Co Shih | 2017 | International Journal of Ophthalmology(English edition)2017，10，2： | 5 |
| 2 | miR-130b Promotes CD133 + Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1显示文摘 | Stephanie Ma Kwan Ho Tang Yuen Piu Chan Terence K. Lee Pak Shing Kwan Antonia Castilho Irene Ng Kwan Man Nathalie Wong Ka-Fai To Bo-Jian Zheng Paul B.S. Lai Chung Mau Lo Kwok Wah Chan Xin-Yuan Guan | 2010 | Cell Stem Cell2010，，： | 2 |
| 3 | Ultrastructural characterization of whole hydrosalpinx from infertile Chinese women显示文摘 | Louis Chukwuemeka Ajonuma Ernest Hung Yu Ng Lin Nga Chan Pak Ham Chow Lai Sin Kung Annie Nga Yin Cheung Lok Sze Ho Christine Briton-Jones Ingrid H. Lok Christopher J. Haines Hsiao Chang Chan | 2005 | Cell Biology International2005，，10： | 1 |
| 4 | T ‐ S pot. TB outperforms tuberculin skin test in predicting development of active tuberculosis among household contacts显示文摘 | Chi Chiu Leung Wing Cheong Yam Pak Leung Ho Wing Wai Yew Chi Kuen Chan Wing Sze Law Shuk Nor Lee Kwok Chiu Chang Lai Bun Tai Cheuk Ming Tam | 2015 | Respirology2015，，3： | 1 |
| 5 | Ovarian changes after abdominal hysterectomy for benign conditions显示文摘 | Carina CW Chan Ernest HY Ng Pak - Chung Ho | 2005 | Journal of the Society for Gynecologic Investigation2005，12，1： | 1 |
| 6 | Highthroughput determination of biochemical oxygen demand(BOD)by a microplate-based biosensor显示文摘 | Pang Hei Leung Kwok Nga Yan Chan Pak Ho | 2007 | Environ Sci Technol2007，，41： | 1 |
| 7 | miR-130b Promotes CD133 + Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1显示文摘 | Stephanie Ma Kwan Ho Tang Yuen Piu Chan Terence K. Lee Pak Shing Kwan Antonia Castilho Irene Ng Kwan Man Nathalie Wong Ka-Fai To Bo-Jian Zheng Paul B.S. Lai Chung Mau Lo Kwok Wah Chan Xin-Yuan Guan | 2010 | Cell Stem Cell2010，，： | 1 |
| 8 | Deep learning based radiomics for gastrointestinal cancer diagnosis and treatment:A minireview显示文摘Gastrointestinal(GI)cancers are the major cause of cancer-related mortality globally.Medical imaging is an important auxiliary means for the diagnosis,assessment and prognostic prediction of GI cancers.Radiomics is an emerging and effective technology to decipher the encoded information within medical images,and traditional machine learning is the most commonly used tool.Recent advances in deep learning technology have further promoted the development of radiomics.In the field of GI cancer,although there are several surveys on radiomics,there is no specific review on the application of deep-learning-based radiomics(DLR).In this review,a search was conducted on Web of Science,PubMed,and Google Scholar with an emphasis on the application of DLR for GI cancers,including esophageal,gastric,liver,pancreatic,and colorectal cancers.Besides,the challenges and recommendations based on the findings of the review are comprehensively analyzed to advance DLR. | Pak Kin Wong In Neng Chan Hao-Ming Yan Shan Gao Chi Hong Wong Tao Yan Liang Yao Ying Hu Zhong-Ren Wang Hon Ho Yu | 2022 | World Journal of Gastroenterology2022，28，45： | 1 |
| 9 | 香港儿童服用低剂量三聚氰胺后肾脏并发症的现况调查研究显示文摘目的 调查香港儿童服用小剂量三聚氰胺后的肾脏并发症。
设计 横断面调查方法。
机构 香港专业评估中心。
调查对象 根据全港初级医疗保健中心的记录,研究包括3170例(1748例男童,1422例女童)≤12岁、连续1个月或以上服用被三聚氰胺污染奶制品的儿童。
主要评估指标 是否存在肾结石和血尿。
结果 1例儿童存在肾结石,7例儿童肾脏内可疑存在三聚氰胺结晶,应用尿试纸检查发现208例(6.6%)儿童存在血尿。这些儿童在专业评估中心进一步检查后,仅有7.4%的儿童确实存在显微镜下血尿,所以总体儿童血尿出现率低于1%。
结论:在曾服用小剂量三聚氰胺的儿童中,没有急性肾功能衰竭或尿路梗阻等严重不良事件发生。我们的研究结果与全港调查一致。即使将7例肾内可疑存在三聚氰胺结晶的患儿包括在内,应用超声检查发现的可疑三聚氰胺相关不良事件发生率也仅为0.2%,且这些患儿尚不需要进一步治疗。应用尿试纸检测是否存在血尿,可能会过高估计血尿的发生率。研究结果提示对于曾服用小剂量三聚氰胺的儿童进行大范围、积极的检查可能并不会得到更多有意义的资料,所以不值得投入更多的经费去进行这种检查。 | Hugh S Lam Pak C Ng Winnie C W Chu William Wong Dorothy F Y Chan Stella S Ho Ka T Wong Anil T Ahuja Chi K Li 张宁(译) 杨勇(校) | 2009 | 英国医学杂志中文版2009，12，3： | 0 |
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