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	题名	作者	年代	出处	被引量
1	Telomerase activity in colorectal cancer,prognostic factor and implications in the microsatellite instability pathway显示文摘AIM: To determine whether the telomerase activity is related to the Microsatellite instability (MSI) genetic pathway and whether it means a difference in the survival. METHODS: The population consisted of 97 colorectal cancer patients. MSI determination was performed in accordance with the NCI criteria using PCR and Genescan. Telomerase activity was determined by the TRAP-assay, an ELISA procedure based on the amplification of telomeric repeat sequences. RESULTS: 6.2% showed high MSI (MSI-H), 10.3% showed low MSI (MSI-L) and 83.5% did not show this alteration (MSS). Positive telomerase activity was detected in 92.8% of the patients. 83.3% of MSI-H tumors showed positive telomerase against 93.8% of MSS tumors. In the overall survival analysis the absence of telomerase activity conferred a better prognosis. CONCLUSION: Previous works have shown that tumors which develop via the MSI pathway present a better prognosis. No link between telomerase activity and MSI status is observed, although sample sizes are small. Patients with telomerase negative tumors had better overall survival than patients with telomerase positive tumors.	M Vidaurreta ML Maestro S Rafael S Veganzones MT Sanz-Casla J Cerdán M Arroyo	2007	World Journal of Gastroenterology2007，13，28：	8
2	Expression and role of Elovl4 elongases in biosynthesis of very long-chain fatty acids during zebrafish Danio rerio early embryonic development显示文摘	Monroig O Rotllant J Cerdá-Reverter JM	2010	Biochim Biophys Acta2010，1801，：	1
3	Successive post - translational modifications of E - eadherin are required for In- 1A - mediated internalization of Listeria monocytogenes显示文摘	BONAZZI M VEIGA E PIZARRO - CERD/ J	2008	Cell Mi- crobiol2008，10，1：	1
4	The contrasting characteristics of acute kidney injury in developed and developing countries显示文摘	Cerdá J Bagga A Kher V		0，，：	1
5	An MILP framework for batch reactive scheduling with limited discrete resources 显示文摘	Mendez C A Cerd J	2004	Computers&Chemical Engineering2004，28，67：	1
6	State-of-the-art review of optimization methods for short-term scheduling of batch processes显示文摘	Méndez C A Cerdá J Grossmann I E	2006	Computer & Chemical Engineering2006，30，67：	1
7	Raising awareness of acute kidney injury: a global perspective of a silent killer显示文摘	Lewington AJ Cerd J Mehta RL	2013	Kidney Int2013，84，3：	1
8	Cloning the neuropeptide Y Exon2 from sea bass (Dicentrarchus labrax) 显示文摘	Cerd a-Reverter J M Martinez-Rodriguez G Zanuys	1999	Comp Biochem Physiol1999，123，：	1
9	A mixed-integer linear programming model for short-term scheduling of single-stage multiproduct batch plants with parallel lines显示文摘	Henning G P Grossmann I E	1997	Ind Eng Chem Res1997，36，：	1
10	Phylogenetic relationships and gene expression pattern of three different cathepsin L (Ctsl)isoforms in zebrafish: Ctsla is the putative yolk processing enzyme 显示文摘	Tingaud-Sequeira A Cerd J	2007	Gene2007，386，12：	1
11	Optimal scheduling of batch plants satisfying multiple product orders with different due-dates显示文摘	Henning G P Cerdá J	2000	Computers and Chemical Engineering2000，24，：	1
12	Optimal scheduling of a resource-constrained multiproduct batch plant supplying intermediates to nearby end-product facilities显示文摘	Cerdá J	2000	Computers and Chemical Engineering2000，24，：	1
13	An MILP-based approach to the short-term scheduling of make-and-pack continuous production plants显示文摘	MINDEZ C A CERD J	2002	OR Spec- trum2002，24，4：	1
14	Enzymatic hydrolysis of the cytotoxic triterpenoid glycoside virgaureasaponin Ⅰ 显示文摘	Cerd B Victor W Ulrich J	1998	Phytochemistry1998，49，1：	1
15	Epidmaiology of acute kidney injury显示文摘	Cerd J Lameire N Eggers P	2008	Clin J Am Soc Nephrol2008，3，3：	1
16	Differential localization and regulation of two aquaporin-1 homologs in the intestinal epithelia of the marine teleost Sparus aurata显示文摘	Raldúa D Otero D Fabra M Cerdà J	2008	Am J Physiol2008，294，99：	1
17	Fish melanocortin system显示文摘	Cerdá-Reverter J M Agulleiro M J Rau'l R G	2011	European Journal of Pharmacology2011，660，1：	1
18	A cluster-based optimization approach for the mul-ti depot heterogeneous fleet vehicle routing problem with time windows显示文摘	Dondo R Cerd á J	2007	European Journal of Operational Research2007，176，3：	1
19	Sow vaccination modulates the colonization of piglets by Haemophilusparasuis显示文摘	CERD魥-CULLAR M NARANJO J F VERGE A	2010	Veterinary Microbiology2010，145，3：	1
20	Single preoperative dose of metronidazole plus gentamicin for antimicrobial prophylaxis in colorectal surgery显示文摘	Ventura Cerdá JM Nomdedeu Guinot J	2007	Med Clin (Barc)2007，129，4：	1

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