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| 1 | Human immune cells' behavior and survival under bioenergetically restricted conditions in an in vitro fracture hematoma model显示文摘骨头骨折愈合的起始的煽动性的阶段为愈合的过程的结果代表关键步。然而,开始这个煽动性的阶段的机制和在破裂地点在场的有免疫力的房间的功能糟糕被理解。以便在破裂 hematoma 以内学习早事件,我们建立了一在里面 vitro 破裂 hematoma 模型:我们有教养的 hematomas 在 bioenergetically 控制的条件下面在 vitro 在全部的新潮的关节造形术(THA ) 期间在腿节的截骨术(人工的骨头破裂) 期间形成。这个模型允许我们在跟随破裂的早阶段期间监视有免疫力的房间人口,房间幸存和 cytokine 表示。而且,这个模型使我们能改变 bioenergetical 条件以便模仿在里面 vivo 状况,它被假定被组织缺氧描绘并且限制了营养素的数量。用这个模型,我们发现有免疫力的房间经由 angiogenic 因素, chemoattractants 和支持 inflammatory 分子的表示适应组织缺氧。另外,联合了氧的限制,滋养的供应与 myeloid 的比较提高了淋巴细胞的选择幸存导出的房间(即, neutrophils ) 。笔记,非限制的 bioenergetical 条件没关于 cytokine 表示或有免疫力的房间子集的不同幸存率显示出任何类似的效果。在结论,我们发现 bioenergetical 条件在导致骨折愈合的起始的煽动性的阶段的关键因素之中并且因此是为在早破裂 hematoma 影响有免疫力的房间的幸存和功能的一个关键步骤。 | Paula Hoff Patrick Maschmeyer Timo Gaber Tabea Schiitze Tobias Raue Katharina Schmidt-Bleek Rene Dziurla Saskia Schellmann Ferenz Leonard Lohanatha Eric Rohner Andrea Ode Gerd-Riidiger Burmester Georg N Duda Carsten Perka Frank Buttgereit | 2013 | Cellular & Molecular Immunology2013，10，2： | 3 |
| 2 | The European Cancer Anaemia Survey (ECAS): A large, multinational, prospective survey defining the prevalence, incidence, and treatment of anaemia in cancer patients显示文摘 | Heinz Ludwig Simon Van Belle Peter Barrett-Lee Gunnar Birgeg?rd Carsten Bokemeyer Pere Gascón Paris Kosmidis Maciej Krzakowski Johan Nortier Patrizia Olmi Maurice Schneider Dirk Schrijvers | 2004 | European Journal of Cancer2004，，15： | 2 |
| 3 | A new fast and reliable radioimmunoassay of brain natriuretic peptide in human plasm显示文摘 | Jesen K T Carstens J Ivarsen N | 1997 | Scand J Clin Lab Invest1997，57，： | 1 |
| 4 | Mapping QTL confer- ring resistance in maize to gray leaf spot disease caused by Cerco- spora zeina显示文摘 | Berger D K Carstens M Korsman J N | 2014 | BMC Genet2014，15，： | 1 |
| 5 | Chromatographic analysis of endogenous retinoids in tissues and serum显示文摘 | CARSTEN K S ABRAHAM B HEINZ N | 2003 | Anal Biochem2003，315，： | 1 |
| 6 | Peptide synthesis in aqueous environments: The role of extreme conditions and pyrite mineral surfaces on formation and hydrolysis of peptides显示文摘 | Schreiner Eduard Nair Nisanth N Wittekindt Carsten | 2011 | Journal of American Chemical Society2011，133，21： | 1 |
| 7 | Marine downhole to seafloor dipole-dipole electromagnetic methods and the resolution o{ resistive targets 显示文摘 | Carsten S Edwards R N | 2007 | Geophysics2007，72，2： | 1 |
| 8 | Radiotherapy for highgrade gliomas does altered fractionafion improve the out-come?显示文摘 | CARSTEN N NICOLAUS A NICOLE W | 2004 | Strahlentherapieund Oncologie2004，7，： | 1 |
| 9 | Radiotherapy for high-grade gliomas显示文摘 | Carsten N Nicolaus A Nicole W | 2004 | Strahlenther Oncol2004，180，7： | 1 |
| 10 | Serum concentrations of antibodies against vaccine toxoids in children显示文摘 | CARSTEN H ESBEN B J FLEMMING N | | 0，，10： | 1 |
| 11 | Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinaseγ显示文摘 | Philipp V Carsten B Bernd N | 2005 | Biol Chem2005，280，6： | 1 |
| 12 | Factors affecting the catalytic activity of Pd/ZrO2 for the combustion of methane显示文摘 | Carstens J N Su S C Bell A T | 1998 | Jour-hal of Catalysis1998，176，1： | 1 |
| 13 | Identification of copper-induced genes in Pseudomoas fluorescens and use of a reporter strain to monitor bioavailable copper in soil显示文摘 | ANDREAS T P CARSTEN H OLE N | 2001 | FEMS Microbiology Ecology2001，38，： | 1 |
| 14 | p ‐ P henylenediamine and other allergens in hair dye products in the U nited S tates: a consumer exposure study显示文摘 | Dathan Hamann Kerem Yazar Carsten R. Hamann Jacob P. Thyssen Carola Lidén | 2014 | Contact Dermatitis2014，，4： | 1 |
| 15 | Development of new a-amylases for raw starch hydrolysis显示文摘 | ANDERS V N CARSTEN A T1NE H | 2006 | Bioeatal Biotransfor2006，24，12： | 1 |
| 16 | Endotracheal suc- tioning of the adult intubated patient-what is the evi- dence显示文摘 | Carsten M Mette N Jeanette H el al | 2009 | Intensive and Critical Nursing2009，25，1： | 1 |
| 17 | Metagenomics to Paleogenomics:Large-Scale Sequencing of Mammoth DNA显示文摘 | Hendrik N P Carsten S Ji Q | | 0，，5759： | 1 |
| 18 | Changes in human fetal oxygenation during maternal hyperoxia as estimated by BOLD MRI显示文摘 | Anne S?rensen David Peters Carsten Simonsen Michael Pedersen Brian Stausb?l‐Gr?n Ole Bjarne Christiansen G?ran Lingman Niels Uldbjerg | 2012 | Prenat Diagn2012，，2： | 1 |
| 19 | Angular distribution of light scattered by single biological cells and oriented particle agglomerates显示文摘 | JORG N CARSTEN G ANDREAS H | 2003 | App Opt2003，42，31： | 1 |
| 20 | Factors affecting the catalytic activity of Pd/ZrO2 for the combustion of methane 显示文摘 | Carstens J N Su S C Bell A T | 1998 | Journal of Catalysis1998，176，： | 1 |
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