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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Silver toxicity to #Chironomus# tentans in two freshwater sediments显示文摘 | CALL D J POLKINGHORNE C N MARKEE T P | 1999 | Environmental Toxicological Chemistry1999，18，1： | 1 |
| 3 | Impact of stone disease:chronic kidney disease and quality of life显示文摘 | KARTHA G CALLE J C MARCHINI G S | 2013 | Urol clin north am2013，40，1： | 1 |
| 4 | Physicians' knowledge of inhaler devices and inha- lation techniques remains poor in Spain显示文摘 | Plaza V Sanchis J Roma P Molina J Calle M Quirce S Viejo JL Ca- ballero F Murio C | 2012 | J Aerosol Med Pulm Dm8 Deliv2012，25，1： | 1 |
| 5 | Comparison of organic acid salts for Clostridium botulinum control in an uncured turkey product显示文摘 | Miller A J Call J E Whiting R C | 1993 | Journal of food protection1993，56，： | 1 |
| 6 | Prevention of infrared-A radiation mediated detrimental effects in human skin显示文摘 | Schroeder P Calles C Krutmann J | 2009 | Skin Therapy Lett2009，14，5： | 1 |
| 7 | Maceration activity of an endopolygalacturonase from Candida macedoniensis 显示文摘 | CALL H P WALTER J EMEIS C C | 1985 | Journal of Food Biochemistry1985，9，4： | 1 |
| 8 | An investigation of the rigor of interpretation rules for STRs derived from less than 100 pg of DNA 显示文摘 | CAll P Whitaker J Flaxman C | 2000 | Forensic Sei Int2000，112，： | 1 |
| 9 | 2005 Guidelines for the diagnosis, prevention and management of heartworm( Dirofilaria immitis ) infection in dogs 显示文摘 | NELSON C T MC CALL J W RUBIN S B etal | 2005 | Vet Parasitol2005，133，3： | 1 |
| 10 | Postpartum clhanges in the uterus and blood of ewes during the anoestrous season 显示文摘 | Foote W C Call J W | 1969 | J Anita Sci1969，29，： | 1 |
| 11 | Natural revegetation ofan unreclaimed lignite surface mine in East - central Texas-USA)显示文摘 | Skousen J G Call C A Knight R W | 1990 | South-western Naturalist1990，35，9： | 1 |
| 12 | Postpartum uterine and ovarian changes, and oestrous behavior from lactation effects in normal and hormone treated ewes 显示文摘 | Call J W Foote W C Eckre C D | 1976 | Theriogenology1976，，6： | 1 |
| 13 | Control of reproductionand sex related behavior in exotic wild carnivores with GnRH analogue deslorelin:preliminary observations显示文摘 | Bertschinger H J Asa C S Calle P P | 2001 | Reprod Fertil2001，，： | 1 |
| 14 | Ce-ZSM-5 catalysts for the selective catalytic reduction of NOx in stationary diesel exhaust gas显示文摘 | Van KOOTEN W E J LIANG B KRIJNSEN H C OUDSHOORN O L CALLS H P A Van den BLEEK C M | 1999 | Appl Catal B1999，21，3： | 1 |
| 15 | Lung cancer,cardiopulmonary mortality and long_term exposure to fine particulate air pollution显示文摘 | Pope C A Burnett R T Thun M J Calle E E Krewski D Ito K Thurston G D | | 0，，： | 1 |
| 16 | Organic carbon partitioning as a basis for predicting the toxicity of chlorpyrifos in sediments显示文摘 | Ankley C T Call D J Cox J S | 1994 | Environmental Toxicity and Chemistry1994，13，： | 1 |
| 17 | Natural revegetation of an unreclaimed lignite surface mine in east-central Texas (USA)显示文摘 | Skousen J G Call C A Knight R W | 1990 | South-western Naturalist1990，35，： | 1 |
| 18 | Two-dimensional electrophoretic analysis of spore proteins of the microsporidia显示文摘 | Langley P C Call J A Somberg E W | 1987 | J Parasitol1987，73，5： | 1 |
| 19 | Postpartum changes in ute- rus and blood of ewes during the anoestrous season显示文摘 | FOOTE W C CALL J W | 1969 | Journal of Animal Science1969，29，： | 1 |
| 20 | Natural revegetation of an unreclaimed lignite surface mine in east central Texas (USA) 显示文摘 | Skousen J G Call C A Knight R W | 1990 | Southwestern Naturalist1990，35，： | 1 |
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