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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Silver toxicity to #Chironomus# tentans in two freshwater sediments显示文摘 | CALL D J POLKINGHORNE C N MARKEE T P | 1999 | Environmental Toxicological Chemistry1999，18，1： | 1 |
| 3 | Immunopathologic alterations in murine models of sepsis of increasing severity显示文摘 | Ebong S Call D Nemzek J | 1999 | Infect hnmun1999，67，12： | 1 |
| 4 | An improved method for preparing very high molecular weight polyimides 显示文摘 | Munoz D M Calle M de La Campa J G | 2009 | Macromoleeules(S0024-9297)2009，42，15： | 1 |
| 5 | Identifying antimicrobial resistance genes with DNA microarrays显示文摘 | Call D R Bakko M K Krug M J | 2003 | Antimicrob Agents Chemother2003，47，： | 1 |
| 6 | A field investigation of the relationship between zinc and acid volatile sulfide concentrations in freshwater sediments 显示文摘 | Ankley G T Liber K Call D J | 1996 | Journal of Aquatic Ecosystem Health1996，5，4： | 1 |
| 7 | Super-high-frequency saw resonators on A1N/Diamond 显示文摘 | RODRIGUEZ-MADRID J IRIARTE G F PEDROS J WILLIAMS O A BRINK D CALLE F | 2012 | IEEE Electron Device Lett2012，33，： | 1 |
| 8 | Role of ceftiofur in selection and dissemination of blaCMY-2-mediated cephalosporin resistance in Salmonella enterica and commensal Escherichia coli isolates from cattle显示文摘 | DANIELS J B CALL D R HANCOCK D | 2009 | Appl Environ Microbiol2009，75，11： | 1 |
| 9 | Molecular connectivity in chemistry and drug research显示文摘 | CALL D J | 1995 | Environ Toxicol Chem1995，4，： | 1 |
| 10 | Immunopathologic alterations in routine models of sepsis of increasing severity 显示文摘 | Ebong S Call D Nemzek J | 1999 | Infect Im- mun1999，67，66： | 1 |
| 11 | Direct detection of 16S rRNA in soil extracts by using oligonucleotide microarrays显示文摘 | SMALL J CALL D R BROCKMAN F J | 2001 | Appl Environ Microbiol2001，67，10： | 1 |
| 12 | Ratio of local to systemic chemokine concentrations regulates neutrophil recruitment显示文摘 | CALL D R NEMZEK J A EBONG S J | 2001 | Am J Pathol2001，158，2： | 1 |
| 13 | Detection of bacterial pathogens in environmental samplesusing DNA microarrays显示文摘 | CALL D R BORUCHI M K LOGE F J | 2003 | Journal of Microbiological Methods2003，，53： | 1 |
| 14 | Combination immunotherapy with soluble tumor necrosis factor receptors plus interleukin 1 receptor antagonist decreases sepsis mortality显示文摘 | REMICK D G CALL D R EBONG S J | 2001 | Crit Care Med2001，29，3： | 1 |
| 15 | Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the National Heart, Lung, and Blood Institute Family Heart Study显示文摘 | Djousse L Amett D K Call J J | 2005 | Circulation2005，111，22： | 1 |
| 16 | Detecting and genotyping Facherichia coli O157:H7 using multiplexed PCR and nucleic acid microarrays显示文摘 | Call D R Brockman F J Chandler D P | 2001 | Int J Food Microbiol2001，67，12： | 1 |
| 17 | Postpartum uterine and ovarian changes, and oestrous behavior from lactation effects in normal and hormone treated ewes 显示文摘 | Call J W Foote W C Eckre C D | 1976 | Theriogenology1976，，6： | 1 |
| 18 | Deteeti on of pathogenic V ibrio spp in shellfish by using multiplex PCR and DNA microarrays显示文摘 | Panicker G Call D R Krug M J | 2004 | Appl EnvironMicr obi ol2004，70，12： | 1 |
| 19 | Carbon materials as electrodes for electrosorption of NaCI in aqueous solutions显示文摘 | Villar l David J Calle S D Gonztilez Z el al | 2011 | Adsorption2011，，17： | 1 |
| 20 | Microbial biofilms 显示文摘 | COSTERTON W J LEWANDOWSK1 Z CALl)WELL D E | 2009 | Annual Review Microbiology2009，49，： | 1 |
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