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| 1 | Transient elastography: a new noninvasive method for assessment of hepatic fibrosis显示文摘 | Laurent Sandrin Bertrand Fourquet Jean-Michel Hasquenoph Sylvain Yon Céline Fournier Frédéric Mal Christos Christidis Marianne Ziol Bruno Poulet Farad Kazemi Michel Beaugrand Robert Palau | 2003 | Ultrasound in Medicine & Biology2003，，12： | 3 |
| 2 | A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity显示文摘Understanding the immune responses elicited by SARS-CoV-2 infection is critical in terms of protection against reinfection and,thus,for public health policy and vaccine development for COVID-19.In this study,using either live SARS-CoV-2 particles or retroviruses pseudotyped with the SARS-CoV-2 S viral surface protein(Spike),we studied the neutralizing antibody(nAb)response in serum samples from a cohort of 140 SARS-CoV-2 qPCR-confirmed infections,including patients with mild symptoms and also more severe forms,including those that required intensive care.We show that nAb titers correlated strongly with disease severity and with anti-spike IgG levels.Indeed,patients from intensive care units exhibited high nAb titers;conversely,patients with milder disease symptoms had heterogeneous nAb titers,and asymptomatic or exclusive outpatient-care patients had no or low nAbs.We found that nAb activity in SARS-CoV-2-infected patients displayed a relatively rapid decline after recovery compared to individuals infected with other coronaviruses.Moreover,we found an absence of cross-neutralization between endemic coronaviruses and SARS-CoV-2,indicating that previous infection by human coronaviruses may not generate protective nAbs against SARS-CoV-2.Finally,we found that the D614G mutation in the spike protein,which has recently been identified as the current major variant in Europe,does not allow neutralization escape.Altogether,our results contribute to our understanding of the immune correlates of SARS-CoV-2-induced disease,and rapid evaluation of the role of the humoral response in the pathogenesis of SARS-CoV-2 is warranted. | Vincent Legros Solène Denolly Manon Vogrig Bertrand Boson Eglantine Siret Josselin Rigaill Sylvie Pillet Florence Grattard Sylvie Gonzalo Paul Verhoeven Omran Allatif Philippe Berthelot Carole Pélissier Guillaume Thiery Elisabeth Botelho-Nevers Guillaume Millet Jérôme Morel Stéphane Paul Thierry Walzer François-Loïc Cosset Thomas Bourlet Bruno Pozzetto | 2021 | Cellular & Molecular Immunology2021，18，2： | 3 |
| 3 | Calcite veins of the Stfipa granite (Sweden) as records of the origin of the groundwaters and their interactions with the granitic body显示文摘 | NORBERT C SHAUN K F BERTRAND F | 1989 | Geochimica et Cosmochimica Acta1989，53，8： | 1 |
| 4 | U373-MG response to interleukin-1 t-induced oxidative stress 显示文摘 | MALAPLATE-ARMAND C GUEGUEN Y BERTRAND P et al | 2000 | Cell Biol Toxicol2000，16，3： | 1 |
| 5 | Glutamine synthetase and glutamate dehydrogenase isoforms in maize leaves:Localization,relative proportion and their role in ammonium assimilation or nitrogen transport显示文摘 | Thomas W B Elisa C Bertrand H | 2000 | Planta2000，211，： | 1 |
| 6 | Microstructure of plasma-sprayed titania coatings deposited from spray-dried powder显示文摘 | Berger-keller N Bertrand G Filiatre C | 2003 | Surface and Coatings Technology2003，168，23： | 1 |
| 7 | Disease complex in coffee involving Meliodogyne arabicida and Fusarium oxysporus 显示文摘 | BERTRAND B NUNEZ C SARAH J L | 2000 | Plant Pathology2000，49，： | 1 |
| 8 | A branch -and -bound algorithmfor makespan minimization in differentiation flow shops显示文摘 | YEN C L KUEI T F BERTRAND L | 2013 | Engineering0ptimization2013，45，12： | 1 |
| 9 | Methodologies for Salmonella enterica subsp, enterica subtyping: gold standrads and alternatives显示文摘 | Wattiau P Boland C Bertrand S | 2011 | Applied and Environmental Microbiology2011，77，22： | 1 |
| 10 | NK1 receptors mediate leukocyte adhesion in neurogenic inflammation in the rat trachea 显示文摘 | Baluk P Bertrand C Geppetti P | 1995 | Am J Physiol1995，268，21： | 1 |
| 11 | The laser welding technique applied to the non precious dental alloys procedure and results显示文摘 | Bertrand C Le Petitcorps Y Albingre L | 2001 | Br Dent J2001，190，5： | 1 |
| 12 | Reversible loss of N-aeetyl-aspanate in rats subjected to longterm focal cerebral ischmfia显示文摘 | Demougeot C Bertrand N Prigent-Tessier A | 2003 | J Cereb Blood Flow Metab2003，23，4： | 1 |
| 13 | Expression of Slit and Robo genes in the developing mouse heart 显示文摘 | Medioni C Bertrand N Mesbah K | 2010 | Dev Dyn2010，239，： | 1 |
| 14 | The PAl - 1 swing: microenvironment and cancer cell migration 显示文摘 | Malo M Charriere - Bertrand C Chettaoui C | 2006 | C R Biol2006，329，12： | 1 |
| 15 | Stress response to hypoxia in gerbil brain:HO-1 and Mn SOD expression and glial activation显示文摘 | Garnier P Demougeot C Bertrand N | 2001 | Brain Res2001，893，12： | 1 |
| 16 | Numerical and experimental study of mixed and forced convection in a junction 显示文摘 | J C Roy C Bertrand | 1994 | Int J Heat Mass Transfer1994，37，14： | 1 |
| 17 | Ceramic com- ponents manufacturing by selective laser sintering显示文摘 | Bertrand Ph Bayle F Combe C | 2007 | Applied Surface Science2007，254，： | 1 |
| 18 | U373-MG response to interleukin-1 beta-induced oxidative stress显示文摘 | Malaplate-Armand C Gueguen Y Bertrand P | 2000 | Cell Biol Toxicol2000，16，3： | 1 |
| 19 | Psychopathology and quality of life for adolescents with asthma and their parents显示文摘 | Vila G Hayder R Bertrand C | 2003 | Psychoso- matics2003，44，4： | 1 |
| 20 | A link between chemokine levels and disease severity in human African trypanosomiasis显示文摘 | Bertrand C Caroline B Ge'de'on | 2006 | Intern J Parasitol2006，36，： | 1 |
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