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| 1 | Promotion of the articular cartilage proteoglycan degradation by T-2 toxin and selenium protective effect显示文摘Objective: To identify the relationship between T-2 toxin and Kashin-Beck disease (KBD),the effects of T-2 toxin on aggrecan metabolism in human chondrocytes and cartilage were investigated in vitro. Methods: Chondrocytes were isolated from human articular cartilage and cultured in vitro. Hyaluronic acid (HA),soluble CD44 (sCD44),IL-1β and TNF-α levels in super-natants were measured by enzyme-linked immunosorbent assay (ELISA). CD44 content in chondrocyte membrane was deter-mined by flow cytometry (FCM). CD44,hyaluronic acid synthetase-2 (HAS-2) and aggrecanases mRNA levels in chondrocytes were determined using reverse transcription polymerase chain reaction (RT-PCR). Immunocytochemical method was used to investigate expressions of BC-13,3-B-3(-) and 2-B-6 epitopes in the cartilage reconstructed in vitro. Results: T-2 toxin inhibited CD44,HAS-2,and aggrecan mRNA expressions,but promoted aggrecanase-2 mRNA expression. Meanwhile,CD44 expression was found to be the lowest in the chondrocytes cultured with T-2 toxin and the highest in control plus selenium group. In addition,ELISA results indicated that there were higher sCD44,IL-1β and TNF-α levels in T-2 toxin group. Similarly,higher HA levels were also observed in T-2 toxin group using radioimmunoprecipitation assay (RIPA). Furthermore,using monoclonal antibodies BC-13,3-B-3 and 2-B-6,strong positive immunostaining was found in the reconstructed cartilage cultured with T-2 toxin,whereas no positive staining or very weak staining was observed in the cartilage cultured without T-2 toxin. Selenium could partly inhibit the effects of T-2 toxin above. Conclusion: T-2 toxin could inhibit aggrecan synthesis,promote aggrecanases and pro-inflammatory cytokines production,and consequently induce aggrecan degradation in chondrocytes. These will perturb metabolism balance between aggrecan synthesis and degradation in cartilage,inducing aggrecan loss in the end,which may be the initiation of the cartilage degradation. | Si-yuan LI Jun-ling CAO Zhong-li SHI Jing-hong CHEN Zeng-tie ZHANG Clare E. HUGHES Bruce CATERSON | 2008 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2008，9，1： | 16 |
| 2 | Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction显示文摘 | Mei Hua Jiang Bing Cai Ying Tuo Jiancheng Wang Zhi Jun Zang Xiang'an Tu Yong Gao Zhijian Su Weiqiang Li Guilan Li Min Zhang Jianwei Jiao Zi Wan Chunhua Deng Bruce T Lahn Andy Peng Xiang | 2014 | Cell Research2014，24，12： | 14 |
| 3 | Regulation of Seed Vigor by Manipulation of Raffinose Family Oligosaccharides in Maize and Arabidopsis thaliana显示文摘棉白糖家庭 oligosaccharides (RFO ) 在许多植物种类在成熟干燥期间在种子积累。然而, RFO 是否在建立种子活力有一个角色,仍然保持不清楚。GALACTINOL SYNTHASE (GOLS ) ,棉白糖 SYNTHASE (RS ) ,和 STACHYOSE SYNTHASE (圣) 是为 RFO 负责的酶 ? 在植物的生合成。有趣地,仅仅棉白糖在玉米种子被检测,并且唯一的玉米 RS 基因(ZmRS ) 被识别。在这研究,我们发现二独立 mutator (亩) 打断了 zmrs 线,不包含棉白糖但是 hyperaccumulating galactinol, ? 显著地减少了种子活力,与空 segregant 控制相比。不同于玉米, Arabidopsis thaliana 种子包含几 RFO (棉白糖, stachyose,和 verbascose ) 。A 的操作。thaliana RFO ? 由 overexpressing ZmGOLS2, ZmRS,或 AtSTS 的内容表明了那 co-overexpression ZmGOLS2 和 ZmRS,或 ZmGOLS2 的 overexpression 独自一个,显著地增加了 RFO 的全部的内容并且提高了 Arabidopsis 种子活力。令人惊讶地,当 ZmRS 的 overexpression 增加了种子棉白糖内容时,它的 overexpression 戏剧性地减少了种子活力并且减少了 galactinol, stachyose,和 verbascose 的种子数量。相反, atrs5 异种种子类似于关于种子活力和 RFO 内容的野类型的那些,除了 stachyose 它在 atrs5 种子积累了。全部的 RFO, RFO/sucrose 比率,然而并非绝对单个 RFO ? 数量,断然与 A 相关。thaliana 种子活力, stachyose 和 verbascose 多于棉白糖作出贡献到。一起拿,这些结果提供新卓见进种子活力的规章的机制并且在 monocot 和 dicot 在 modulating 种子活力为 RFO 揭示不同要求。 | Tao Li Yumin Zhang Dong Wang Ying Liu Lynnette M.A. Dirk Jack Goodman A. Bruce Downie Jianmin Wang Guoying Wang Tianyong Zhao | 2017 | Molecular Plant2017，10，12： | 13 |
| 4 | Assessment of energy release mechanisms contributing to coal burst显示文摘Coal burst is a dynamic release of energy within the rock(or coal) mass leading to high velocity expulsion of the broken/failed material into mine openings. This phenomenon has been recognised as one of the most catastrophic failures associated with the coal mining industry, which can often lead to injuries and fatalities of miners as well as significant production losses. This paper aims to examine the mechanisms contributing to coal burst occurrence, with an emphasis on the energy release concept. In this study, a numerical modelling study has been conducted to evaluate the roles and contributions of difference energy components. The energy analysis presented in this paper can help to improve the understanding of energy release mechanisms especially under Australian conditions. | Zhang Chengguo Canbulat Ismet Tahmasebinia Faham Hebblewhite Bruce | 2017 | International Journal of Mining Science and Technology2017，27，1： | 7 |
| 5 | Nicotine-induced upregulation of antioxidant protein Prx 1 in oral squamous cell carcinoma显示文摘Nicotine is a source of exogenous oxidative stress, which is associated with the pathogenesis of numerous diseases including oral squamous cell carcinoma (OSCC), whereas an antioxidant protein, peroxiredoxin 1 (Prx 1), plays an important role in the modulation of this condition. This study was to investigate the association between Prx 1 and tobacco-induced oxidative stress. The expression of Prx 1 and GST in OSCC Tca8113 cells, which were pre-treated with nicotine, was determined. In the present study, MTT assay, reactive oxygen species (ROS) assay, RT-PCR and Western blot analyses, respectively, were conducted to assess cell viability, ROS level, and expression level of Prx 1 and GST in nicotine-treated Tca8113 cells. Nuclear factor kappa B (NF- B) expression was detected by immuno-fluorescence. Our results showed the growth of Tca8113 cells was increased in a dose-dependent manner when cells were treated with nicotine at concentrations from 0.1 to 10 mol/L, but the proliferation of the cells decreased at 100 mol/L. ROS levels increased in all groups treated with nicotine at concentrations of 0.1, 1, 10, or 100 mol/L for 24h. Prx 1 and GST mRNA and protein expression were up-regulated in cells treated with nicotine for the same time at different concentrations or at the same concentration for different times (P<0.05). NF-B was translocated from cytoplasm to nucleus, the expression of NF- B was increased in nucleus. These results suggest that up-regulation of Prx1 expression appears to be associated with tobacco-induced oxidative stress, which may play an important role in the pathogenesis of OSCC. | ZHAO YanHua ZHANG Min YAN Fei CASTO Bruce C TANG XiaoFei | 2013 | Chinese Science Bulletin2013，58，16： | 7 |
| 6 | Impaired granulocyte-macrophage colony-stimulating factor bioactivity accelerates surgical recurrence in ileal crohn's disease显示文摘AIM To examine the relationship between elevated granulocyte-macrophage colony-stimulating factor(GMCSF) auto-antibodies(Ab) level and time to surgical recurrence after initial surgery for Crohn's disease(CD). METHODS We reviewed 412 charts from a clinical database at tertiary academic hospital. Patients included in the study had ileal or ileocolonic CD and surgical resection of small bowel or ileocecal region for management of disease. Serum samples were analyzed for serological assays including GM-CSF cytokine, GM-CSF Ab, ASCA Ig G and Ig A, and genetic markers including SNPs rs2066843, rs2066844, rs2066845, rs2076756 and rs2066847 in NOD2, rs2241880 in ATG16 L1, and rs13361189 in IRGM. Cox proportional-hazards models were used to assess the predictors of surgical recurrence.RESULTS Ninety six percent of patients underwent initial ileocecal resection(ICR) or ileal resection(IR) and subsequently 40% of patients required a second ICR/IR for CD. GMCSF Ab level was elevated at a median of 3.81 mcg/mL. Factors predicting faster time to a second surgery included elevated GM-CSF Ab [hazard ratio(HR) 3.52, 95%CI: 1.45-8.53, P = 0.005] and elevated GM-CSF cytokine(HR = 2.48, 95%CI: 1.31-4.70, P = 0.005). Factors predicting longer duration between first and second surgery included use of Immunomodulators(HR = 0.49, 95%CI: 0.31-0.77, P = 0.002), the interaction effect of low GM-CSF Ab levels and smoking(HR = 0.60, 95%CI: 0.45-0.81, P = 0.001) and the interaction effect of low GM-CSF cytokine levels and ATG16 L1(HR = 0.65, 95%CI: 0.49-0.88, P = 0.006).CONCLUSION GM-CSF bioavailability plays a critical role in maintaining intestinal homeostasis. Decreased bioavailability coupled with the genetic risk markers and/or smoking results in aggressive CD behavior. | Grace Gathungu Yuanhao Zhang Xinyu Tian Erin Bonkowski Leahana Rowehl Julia Krumsiek Billy Nix Claudia Chalk Bruce Trapnell Wei Zhu Rodney Newberry Lee Denson Ellen Li | 2018 | World Journal of Gastroenterology2018，24，5： | 5 |
| 7 | Long‐term entecavir therapy results in the reversal of fibrosis/cirrhosis and continued histological improvement in patients with chronic hepatitis B显示文摘 | Ting‐Tsung Chang Yun‐Fan Liaw Shun‐Sheng Wu Eugene Schiff Kwang‐Hyub Han Ching‐Lung Lai Rifaat Safadi Samuel S. Lee Waldemar Halota Zachary Goodman Yun‐Chan Chi Hui Zhang Robert Hindes Uchenna Iloeje Suzanne Beebe Bruce Kreter | 2010 | Hepatology2010，，： | 4 |
| 8 | Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial显示文摘 | Craig S Anderson Yining Huang Ji Guang Wang Hisatomi Arima Bruce Neal Bin Peng Emma Heeley Christian Skulina Mark W Parsons Jong Sung Kim Qing Ling Tao Yue Chun Li Jian Dong Jiang Li Wen Tai Jin Li Zhang En Xu Yan Cheng Stephane Heritier Lewis B Morgenste | 2008 | Lancet Neurology2008，，5： | 4 |
| 9 | Bioreduction of vanadium(V) in groundwater by autohydrogentrophic bacteria:Mechanisms and microorganisms显示文摘As one of the transition metals, vanadium(V)(V(V)) in trace amounts represents an essential element for normal cell growth, but becomes toxic when its concentration is above 1 mg/L. V(V) can alter cellular differentiation, gene expression, and other biochemical and metabolic phenomena. A feasible method to detoxify V(V) is to reduce it to V(IV), which precipitates and can be readily removed from the water. The bioreduction of V(V) in a contaminated groundwater was investigated using autohydrogentrophic bacteria and hydrogen gas as the electron donor. Compared with the previous organic donors,H2 shows the advantages as an ideal electron donor, including nontoxicity and less production of excess biomass. V(V) was 95.5% removed by biochemical reduction when autohydrogentrophic bacteria and hydrogen were both present, and the reduced V(IV)precipitated, leading to total-V removal. Reduction kinetics could be described by a first-order model and were sensitive to p H and temperature, with the optimum ranges of p H 7.5–8.0 and 35–40°C, respectively. Phylogenetic analysis by clone library showed that the dominant species in the experiments with V(V) bioreduction belonged to theβ-Proteobacteria. Previously known V(V)-reducing species were absent, suggesting that V(V)reduction was carried out by novel species. Their selective enrichment during V(V)bioreduction suggests that Rhodocyclus, a denitrifying bacterium, and Clostridium, a fermenter known to carry out metal reduction, were responsible for V(V) bioreduction. | Xiaoyin Xu Siqing Xia Lijie Zhou Zhiqiang Zhang Bruce E.Rittmann | 2015 | Journal of Environmental Sciences2015，27，4： | 4 |
| 10 | Preferential CTL targeting of Gag is associated with relative viral control in long-term surviving HIV-1 infected former plasma donors from China显示文摘它通常被相信细胞毒素的 T 淋巴细胞(CTL ) 玩的那 CD8 + 在限制人的免疫不全病毒类型 1 的复制(HIV-1 ) 并且在决定感染的结果,和这效果可以部分优先地取决于产品是哪个 HIV 的一个关键角色指向了。在以前的血浆施主(FPD ) 的一个队探讨在 HIV-1-specific CTL 回答和病毒复制之间的关联,天真的 FPD 与 HIV-1 clade B' 紧张感染了的 143 antiretroviral 治疗与 IFN-γ 为 HIV-1-specific CTL 回答被估计;在由使用盖住整个一致 clade B proteome 的重叠的肽(OLP ) 的单个肽水平的 Elispot 试金。由使用一个枪兵的等级关联分析,当是断然相关到 CD4 计数时,我们发现在全部的病毒特定的 CTL 活动之中的作呕特定的 CTL 回答的比例相反地与病毒的负担被相关,与与增加的病毒的负担被联系并且减少的Pol特定、Env特定的回答对比, CD4 数。另外, Vpr-specifc CTL 回答显示出类似的保护的效果与作呕回答,但是与识别的低得多的频率。显著地,我们也观察了在 HLA 之间的一个协会 --*30/B*13/Cw*06 haplotype 和可能由于的更低的病毒的负担限制了作呕特定的 CTL 回答。因此,我们的数据在疾病控制表明作呕特定的 CTL 回答的突出的角色。HLA 的优点 -- 在病毒的控制的 *30/B*13/Cw*06 haplotype 可以在学习个人与作呕特定的 CTL 回答的贡献被联系。 | Mingming Jia Kunxue Hong Jianping Chen Yuhua Ruan Zhe Wang Bing Su Guoliang Ren Xiaoqing Zhang Zhen Liu Quanbi Zhao Dan Li Hong Peng Marcus Altfeld Bruce D Walker Xu G Yu Yiming Shao | 2012 | Cell Research2012，22，5： | 3 |
| 11 | A semi-quantitative coal burst risk classification system显示文摘Safety is the highest priority in the mining industry as underground mining in particular poses high safety risks to its workers. In underground coal mines, coal bursts are one of the most catastrophic hazards, which involves sudden and violent dynamic coal mass failure with rapid ejection of the broken material into the mine workings. Despite decades of research, the contributing mechanisms of coal bursts are still not completely understood. Hence, it remains challenging to forecast coal bursts and quantify their likelihood of occurrence. However, a range of geological and geotechnical factors are associated with coal bursts and can increase the coal burst proneness. This paper introduces a semi-quantitative coal burst risk classification system, namely, BurstRisk. Based on back-analysis of case histories from Australia, China and the United States, BurstRisk classifies the coal burst risk into three categories:low, medium and high risk. In addition, it allows mining engineers to modify the weighting of the selected factors based on specific conditions. The risk classification charts introduced are for both longwall retreat and development sections of long-wall mining operations. This paper also provides a set of risk management strategies and control measures for effective coal burst mitigation. | Onur Vardar Chengguo Zhang Ismet Canbulat Bruce Hebblewhite | 2018 | International Journal of Mining Science and Technology2018，28，5： | 3 |
| 12 | Modeling Climate Change Impacts on the US Agricultural Exports显示文摘Climate change is expected to have substantial effects on agricultural productivity worldwide. However, these impacts will differ across commodities, locations and time periods. As a result, landowners will see changes in relative returns that are likely to induce modifications in production practices and land allocation. In addition, regional variations in impacts can alter relative competitiveness across countries and lead to adjustments in international trade patterns. Thus in climate change impact studies it is likely useful to account for worldwide productivity effects. In this study, we investigate the implications of considering rest of world climate impacts on projections of the US agricultural exports. We chose to focus on the US because it is one of the largest agricultural exporters. To conduct our analyses, we consider four alternative climate scenarios, both with and without rest of world climate change impacts. Our results show that considering/ignoring rest of world climate impacts causes signifi cant changes in the US production and exports projections. Thus we feel climate change impact studies should account not only for climate impacts in the country of focus but also on productivity in the rest of the world in order to capture effects on commodity markets and trade potential. | ZHANG Yu-quan CAI Yong-xia Beach Robert H McCARL Bruce A | 2014 | Journal of Integrative Agriculture2014，13，4： | 3 |
| 13 | Competition for electrons between reductive dechlorination and denitrification显示文摘 | Lifeng Cao Weihua Sun Yuting Zhang Shimin Feng Jinyun Dong Yongming Zhang Bruce E. Rittmann | 2017 | Frontiers of Environmental Science & Engineering2017，11，6： | 3 |
| 14 | Establishment and characterization of two new human embryonic stem cell lines,SYSU-1 and SYSU-2显示文摘背景人的胚胎的干细胞能在 vitro 无止境地宣传并且能区分进所有三胚胎的细菌层的衍生物。主要在他们的潜力包围人的胚胎的干细胞谎言生产的兴奋专业化能被用于的房间移植治疗。然而,进一步的调查与改变基因背景要求另外的房间线。因此,导出并且建立更多的人的胚胎的干细胞线的努力是高度,从施主的 warranted.Methods 剩余胚胎(胚囊) 被用来由 immunosurgery 孤立内部房间团。所有房间在照耀的鼠科的胚胎的成纤维细胞上连续地是有教养的喂层和多半人的胚胎的干细胞殖民地被房间表面标记染色, karyotyping 和 teratoma formation.Results 随后描绘二根人的胚胎的干细胞线(SYSU-1 和 SYSU-2 ) 从剩余胚胎被建立。二根线表示包括碱的磷酸酶, SSEA- 4, Tra-1-60, Oct-4, Nanog 和 Rex-1.They 的标记在延长段落以后与正常 karyotype 处于无差别的状态仍然是的几 pluripotency 并且能在 vivo.Conclusion 在 vitro 和 teratoma 形成胚胎植物或动物身体二根新人的胚胎的干细胞线从剩余胚胎被建立了。他们能被用来理解 selfrenewal 和区分的机制并且为再生药提供更多的选择。 | HUANG Guo LI Wei-qiang CHEN Rui CHEN Zhen-guang ZHANG Xiu-ming MAO Fu-xiang HUANG Shao-liang LI Shu-nong Bruce T Lahn Andy Peng Xiang | 2007 | Chinese Medical Journal2007，，7： | 3 |
| 15 | A framework infrageneric classification of Carex (Cyperaceae) and its organizing principles显示文摘Phylogenetic studies of Carex L.(Cyperaceae)have consistently demonstrated that most subgenera and sections are para-or polyphyletic.Yet,taxonomists continue to use subgenera and sections in Carex classification.Why?The Global Carex Group(GCG)here takes the position that the historical and continued use of subgenera and sections serves to(i)organize our understanding of lineages in Carex,(ii)create an identification mechanism to break the~2000 species of Carex into manageable groups and stimulate its study,and(iii)provide a framework to recognize morphologically diagnosable lineages within Carex.Unfortunately,the current understanding of phylogenetic relationships in Carex is not yet sufficient for a global reclassification of the genus within a Linnean infrageneric(sectional)framework.Rather than leaving Carex classification in its current state,which is misleading and confusing,we here take the intermediate steps of implementing the recently revised subgeneric classification and using a combination of informally named clades and formally named sections to reflect the current state of our knowledge.This hybrid classification framework is presented in an order corresponding to a linear arrangement of the clades on a ladderized phylogeny,largely based on the recent phylogenies published by the GCG.It organizes Carex into six subgenera,which are,in turn,subdivided into 62 formally named Linnean sections plus 49 informal groups.This framework will serve as a roadmap for research on Carex phylogeny,enabling further development of a complete reclassification by presenting relevant morphological and geographical information on clades where possible and standardizing the use of formal sectional names. | Eric H.Roalson Pedro Jiménez-Mejías Andrew L.Hipp Carmen Benítez-Benítez Leo P.Bruederle Kyong-Sook Chung Marcial Escudero Bruce A.Ford Kerry Ford Sebastian Gebauer Berit Gehrke Marlene Hahn Muhammad Qasim Hayat Mathias H.Hoffmann Xiao-Feng Jin Sangtae Kim Isabel Larridon Étienne Léveillé-Bourret Yi-Fei Lu Modesto Luceño Enrique Maguilla Jose IgnacioMárquez-Corro Santiago Martín-Bravo Tomomi Masaki Mónica Míguez Robert F.C.Naczi Anton A.Reznicek Daniel Spalink Julian R.Starr Uzma Tamara Villaverde Marcia J.Waterway Karen L.Wilson and Shu-Ren Zhang | 2021 | Journal of Systematics and Evolution2021，59，4： | 3 |
| 16 | Cleavage of serum response factor mediated by enteroviral protease 2A contributes to impaired cardiac function显示文摘Enteroviral 感染能导致扩大心肌症(DCM ) ,它是世界范围的心血管的死亡的一个主要原因。然而,病原的机制充分没被阐明。浆液反应因素(SRF ) 是控制许多目标基因的表示的一个心脏充实抄写管理者,包括涉及可收缩的仪器和立即的早反应的那些,以及 microRNAs 那沉默心脏的规章的因素的表示。在心的 SRF 的大美人导致心脏的可收缩的基因表示的 downregulation 和 DCM 的开发。这研究的目标是在导致 enterovirus 的心脏的机能障碍和前进理解 SRF 的角色到 DCM。这里,我们报导 SRF 被劈开跟随老鼠心和有教养的 cardiomyocytes 的 enteroviral 感染。这劈开被心脏特定的可收缩、规章的基因的损害心脏的功能和 downregulation 伴随。由印射的抗体 epitope 和指导地点的 mutagenesis 的进一步的调查证明那 SRF 劈开通过编码病毒的朊酶 2A 的行动发生在它的 transactivation 领域的区域。而且,我们证明 SRF 的那劈开分裂它从 DNA 有约束力的领域的 transactivation 领域,导致调停 SRF 的基因 transactivation 的混乱。除了功能的 SRF 的损失,最后,我们报导 SRF 劈开产品的 N 终端碎片能也充当一个主导否定的抄写因素,它多半为 DNA 绑定与本国的 SRF 竞争。我们的结果建议病毒感染由损害心功能的机制并且可以提供新治疗学的策略改善 DCM 的心肌的损坏和前进。 | Jerry Wong Jingchun Zhang Bobby Yanagawa Zongshu Luo Xiangsheng Yang Jiang Chang Bruce McManus Honglin Luo | 2012 | Cell Research2012，22，2： | 3 |
| 17 | Functional Analysis of Semi-conserved Transit Peptide Motifs and Mechanistic Implications in Precursor Targeting and Recognition显示文摘超过 95% 质体蛋白质作为他们包含作为运输肽(TP ) 知道的 N 终端延期的先锋是原子编码。尽管高度可变, TP 指导先锋通过一保存, posttranslational 机制包含 translocons 在外部(TOC ) 并且内部信封(TOC ) 。细胞器进口特性被 Toc 建筑群的至少一个部件调停。然而,高 TP 差异创造序列怎么能明确地被认出的悖论。TP 设计的一个新兴的模型是他们包含在指向和运输过程在不同的步被认出的多重泛泛地保存的主题。生物信息学证明了许多 TP 包含保存半的物理化学的主题,称为的 FGLK。以便在 TP 识别和进口描绘 FGLK 主题,我们从 RuBisCO 小子单元(SStp ) 和铁氧化还原蛋白(Fdtp ) 的先锋分析了二学习得好的 TP。SStp 和 Fdtp 包含二个 FGLK 主题。在在 vitro,在 organello,并且在 vivo 使用的这二个主题的大集合变化(85 ) 的分析接近支持 FGLK 领域在调停的一个模型和 TOC34 并且可能的相互作用另外的 TOC 部件。在 vivo 进口,分析建议多重 FGLK 主题是机能上地冗余的。而且,我们讨论 FGLK 主题怎么为有效先锋蛋白质进口被要求并且这些元素怎么可以允许指向序列的这个高度可变的类的一个会聚的函数。 | Kristen Holbrook Chitra Subramanian Prakitchai Chotewutmontri L. Evan Reddick Sarah Wright Huixia Zhang Lily Moncrief Barry D. Bruce | 2016 | Molecular Plant2016，9，9： | 3 |
| 18 | Coupled aerobic and anoxic biodegradation for quinoline and nitrogen removals显示文摘喹啉(C 9 H 7 N ) 通常从化学药品,药品,和染的工业发生在废水。因为喹啉是 biodegraded,氮作为铵被释放。Total-N 移动要求 ammonium-N 被使硝化然后从。这研究的目的是与 total-N 移动联合喹啉 biodegradation。在 proof-of-concept 步,激活污泥被定序从对缺氧的阶段氧气。在氧气的阶段免除喹啉 biodegradation 的铵氮在平行被使硝化到硝酸盐。氧气的自河的缺氧的 biodegradation 然后通过 denitrification 引起了氮和货到付款移动。然后,同时的喹啉 biodegradation 和 total-N 移动在新奇空运被表明有氧气、缺氧的地区的内部环 biofilm 反应堆(AILBR ) 。当葡萄糖作为一个补加的电子施主增加了时,一旦硝酸盐被形成,试验性的结果证明 AILBR 能完成喹啉, 91% 货到付款移动,和 85% total-N 移动的完全的移动。 | Ning YAN Lu WANG Ling CHANG Cuiyi ZHANG Yang ZHOU Yongming ZHANG Bruce E. RITTMANN | 2015 | Frontiers of Environmental Science & Engineering2015，9，4： | 2 |
| 19 | Interleukin-6 Is Required for Pancreatic Cancer Progression by Promoting MAPK Signaling Activation and Oxidative Stress Resistance显示文摘 | Yaqing Zhang Wei Yan Meredith A. Collins Filip Bednar Sabita Rakshit Bruce R. Zetter Ben Z. Stanger Ivy Chung Andrew D. Rhim Marina Pasca di Magliano | 2013 | Cancer Research2013，，20： | 2 |
| 20 | Estimating GFR Using Serum Cystatin C Alone and in Combination With Serum Creatinine: A Pooled Analysis of 3,418 Individuals With CKD显示文摘 | Lesley A. Stevens Josef Coresh Christopher H. Schmid Harold I. Feldman Marc Froissart John Kusek Jerome Rossert Frederick Van Lente Robert D. Bruce Yaping (Lucy) Zhang Tom Greene Andrew S. Levey | 2008 | American Journal of Kidney Diseases2008，，3： | 2 |
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