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| 1 | 肛裂临床诊治指南(第三次修订)显示文摘“美国结直肠外科医师协会(American Societyof ColonandRectal Surgeons.ASCRS)”(协会)致力于推进结直肠和肛门疾病的相关理论以及预防和诊疗水平的提高,给患者提供优质的医疗服务。“标准委员会”由协会中在结直肠外科方面有显著专长的成员组成。该委员会的建立是为了引领国际结直肠和肛门疾病诊治的发展,以建立具有循证医学证据的临床诊疗指南。指南是涵盖性的,非指令性的,目的是为临床决策提供信息,而非具体的治疗方法。指南适用于所有相关的医护人员以及希望得到相应指南中疾病的相关诊治信息的患者。 | Farshid Araghizadeh ~ Robin Boushey Sridhar Chalasani George Chang Robert Cima Gary Dunn Daniel Feingold Philip Fleshner Daniel Geisler Jill Genua Sharon Gregorcyk Daniel Herzig Andreas Kaiser Ravin Kumar David Larson Steven Mills John Monson P. Terry Phang Feza Remzi David Rivadeneira Howard Ross Peter Senatore Elin Sigurdson Thomas Stahl Scott Steele Scott Strong Charles Tement Judith Trudel Madhulika Varnna Martin Weiser 丁义江(译) 皇甫少华(译) 丁曙晴(译) | 2013 | 中华胃肠外科杂志2013，16，7： | 70 |
| 2 | Increased expression of tumor necrosis factor-a is associated with advanced colorectal cancer stages显示文摘AIM:To detect the expression of tumor necrosis factor-a(TNF-a)in colorectal cancer(CRC)cells among Saudi patients,and correlate its expression with clinical stages of cancer.METHODS:Archival tissue specimens were collected from 30 patients with CRC who had undergone surgical intervention at King Khalid University Hospital.Patient demographic information,including age and gender,tumor sites,and histological type of CRC,was recorded.To measure TNF-a m RNA expression in CRC,total RNA was extracted from tumor formalin-fixed,paraffinembedded,and adjacent normal tissues.Reverse transcription and reverse transcription polymerase chain reaction were performed.Colorectal tissue microarrays were constructed to investigate the protein expression of TNF-a by immunohistochemistry.RESULTS:The relative expression of TNF-a m RNA in colorectal cancer was significantly higher than that seen in adjacent normal colorectal tissue.High TNF-a gene expression was associated with StageⅢandⅣneoplasms when compared with earlier tumor stages(P=0.004).Eighty-three percent of patients(25/30)showed strong TNF-a positive staining,while only 10%(n=3/30)of patients showed weak staining,and 7%(n=2/30)were negative.We showed the presence of elevated TNF-a gene expression in cancer cells,which strongly correlated with advanced stages of tumor.CONCLUSION:High levels of TNF-a expression could be an independent diagnostic indicator of colorectal cancer,and targeting TNF-a might be a promising prognostic tool by assessment of the clinical stages of CRC. | Omar A Al Obeed Khayal A Alkhayal Abdulmalik Al Sheikh Ahmad M Zubaidi Mansoor-Ali Vaali-Mohammed Robin Boushey James H Mckerrow Maha-Hamadien Abdulla | 2014 | World Journal of Gastroenterology2014，20，48： | 8 |
| 3 | Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors显示文摘 | Fatima Haggar Robin Boushey | 2009 | Clinics in Colon and Rectal Surgery2009，，04： | 6 |
| 4 | Colorectal cancer epidemiology: incidence, mortality, survival, and risk factors 显示文摘 | Haggar F A Boushey R P | 2009 | Clin Colon Rectal Surg2009，22，4： | 1 |
| 5 | Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors显示文摘 | Fatima Haggar Robin Boushey | 2009 | Clinics in Colon and Rectal Surgery2009，，04： | 1 |
| 6 | Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids显示文摘 | Woodruff P G Boushey H A Dolganov G M | 2007 | Proc Natl Acad Sci USA2007，104，15： | 1 |
| 7 | Laparoscopic colon surgery; past,present and future显示文摘 | Martel G Boushey RP | 2006 | Surg Clin North Am2006，86，4： | 1 |
| 8 | Laparoscopic repair of paraesophageal hernias:a Canadian experience显示文摘 | Boushey RP Moloo H Burpee S | 2008 | Can J Surg2008，51，5： | 1 |
| 9 | A quantitative assessment of plasma homocysteine as a risk factor for vascular disease显示文摘 | Boushey CJ Beresford SAA Omenn GS | 1995 | JAMA1995，274，： | 1 |
| 10 | Daily versus as -needed corticosteroids for mild persistent asthma显示文摘 | Boushey HA Sorkness CA King TS | 2005 | N Engl J Med2005，352，15： | 1 |
| 11 | A quantitative assessment of plasma homocysteine as a risk factor for vascular disease显示文摘 | Boushey CJ | 1995 | JAMA1995，274，： | 1 |
| 12 | Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study显示文摘 | Bateman ED Boushey HA Bousquet J | | 0，，08： | 1 |
| 13 | A quantitative assessment of plasma homocysteine as a risk factor for vascular disease:probable benefits of increasing folic acid intake显示文摘 | Boushey CJ Beresford AA Omenn GS | 1995 | JAMA1995，274，： | 1 |
| 14 | Daily versus as - needed corticosteroids for mild persistent asthma 显示文摘 | BOUSHEY H A SORKNESS C A KING T S | 2005 | N Engl J Med2005，352，： | 1 |
| 15 | Laparoscopic total colectomy:an evolutionary experience显示文摘 | Boushey RP Marcello PW Martel G | | 0，，： | 1 |
| 16 | A guantitative assssment of plasma homocysteine as a risk factor for vascular disease:probable benefits of increasing folic acid intake显示文摘 | Beresford SAA Omenn GS | 1995 | JAMA1995，274，： | 1 |
| 17 | Macrolides asthma, inflammation, and infection 显示文摘 | Vila P C Boushey H A | 2000 | Ann Allergy Asthma hnmunol2000，84，6： | 1 |
| 18 | Complications in laparoscopic intestinal surgery: prevention and management 显示文摘 | Trottier DC Martel G Boushey RP | 2009 | Minerva Chit2009，64，4： | 1 |
| 19 | A quantitat as- sessment of plasma homocysteine as a risk factor for vascu- lar disease:probable Benefits of increasing folic acid intakes 显示文摘 | Boushey C J Beresfoud SA Omenn GS | 1995 | JAMA1995，274，： | 1 |
| 20 | A quantitative assess- ment of plasma homocysteine as a risk factor for vascular disease 显示文摘 | Boushey C J Beresford SA Omenn GS | 1995 | JAMA1995，274，： | 1 |
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