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| 1 | Tibetan Plateau climate dynamics: recent research progress and outlook显示文摘This paper reviews progress in the study of Tibetan Plateau(TP) climate dynamics over the past decade.Several theoretical frameworks, including thermal adaptation and the TP sensible heat(SH) driving air-pump, have been developed to identify the mechanisms responsible for the circulation anomaly produced by thermal forcing of the TP. Numerical simulations demonstrate that the thermal efects of large-scale orography, including the Tibetan and Iranian Plateaus(TIP), are crucial for the formation of the East Asian and South Asian summer monsoons(SASM) because the surface SH of the TIP is the major driver of the water vapor transport required for the genesis of the north branch of the SASM. he large-scale orography of the TP afects the Asian climate through thermal forcing in spring and summer, and mechanical forcing in winter. he TP forcing can also inluence the Asian summer monsoon(ASM) onset over the Bay of Bengal(BOB) by enhancing the BOB warm pool at the surface and by modulating the South Asian High(SAH) in the upper troposphere. On intra-seasonal timescales, the TP thermal forcing signiicantly modulates spring rainfall in southern China and generates the biweekly oscillation of the SAH in summer. Despite climate warming, the atmospheric heat source over the TP, particularly the spring SH,exhibits a clear weakening trend from the 1980 s to 2000 s. his weakening of the spring SH contributed to the anomalous ‘dry in the north' and ‘wet in the south' rainfall patern observed over East China. Also discussed are challenges to further understanding the mechanism of TP forcing on the multi-scale variability of the ASM. | Guoxiong Wu Anmin Duan Yimin Liu Jiangyu Mao Rongcai Ren Qing Bao Bian He Boqi Liu Wenting Hu | 2015 | National Science Review2015，2，1： | 51 |
| 2 | Roles of forced and inertially unstable convection development in the onset process of Indian summer monsoon显示文摘The NCEP/NCAR R1 reanalysis data are employed to investigate the impact of forced and inertial instability in the lower troposphere over the Arabian Sea on the onset process of Indian summer monsoon(ISM),and to reveal the important role of zonal advection of zonal geostrophic momentum played in the forced unstable convection.Results show that during the ISM onset the zero absolute vorticity contour(??=0)shifts northward due to the strong cross-equatorial pressure gradient in the lower troposphere over southern Arabian Sea.Thus a region with negative absolute vorticity is generated near the equator in the northern hemisphere,manifesting the evident free inertial instability.When a southerly passes through this region,under the influence of friction a lower convergence that facilitates the convection flourishing at the lower latitudes appears to the north of zero absolute vorticity contour.However,owing to such a traditional inertial instability,the convection is confined near the equator which does not have direct influence on the ISM onset.On the contrary in the region to the north of the zero absolute vorticity contour and to the south of the low pressure center near the surface,although the atmosphere there is inertially stable,the lower westerly jet can develop and bring on the apparent zonal advection of zonal geostrophic momentum.Both theoretical study and diagnosing analysis present that such a zonal advection of geostrophic momentum is closely associated with the zonal asymmetric distribution of meridional land-sea thermal contrast,which induces a convergence center near and further north of the westerly jet in the lower troposphere over the southwestern coast of the Indian Peninsula,providing a favorable lower circulation for the ISM onset.It illustrates that the development of convection over the Arabian Sea in late spring and early summer is not only due to the frictional inertial instability but also strongly affected by the zonal asymmetric distribution of land-sea thermal contrast.Moreover,before the ISM onset due to the eastward development of the South Asian High(SAH)in the upper troposphere,high potential vorticity is transported to the region over the Arabian Sea.Then a local trumpet-shaped stream field is generated to cause the evident upper divergence-pumping effect which favors the ISM onset.When the upper divergence is vertically coupled with the lower convergence resulted from the aforementioned forced unstable convection development near the southwestern coast of Indian Peninsula,the atmospheric baroclinic unstable development is stimulated and the ISM onset is triggered. | WU GuoXiong LIU BoQi | 2014 | Science China Earth Sciences2014，57，7： | 5 |
| 3 | A Comparative Study on the Dominant Factors Responsible for the Weaker-than-expected El Ni?o Event in 2014显示文摘Anomalous warming occurred in the equatorial central-eastern Pacific in early May 2014,attracting much attention to the possible occurrence of an extreme El Ni?o event that year because of its similarity to the situation in early 1997. However,the subsequent variation in sea surface temperature anomalies(SSTAs) during summer 2014 in the tropical Pacific was evidently different to that in 1997,but somewhat similar to the situation of the 1990 aborted El Ni?o event. Based on NCEP(National Centers for Environmental Prediction) oceanic and atmospheric reanalysis data,the physical processes responsible for the strength of El Ni?o events are examined by comparing the dominant factors in 2014 in terms of the preceding instability of the coupled ocean–atmosphere system and westerly wind bursts(WWBs) with those in 1997 and 1990,separately. Although the unstable ocean–atmosphere system formed over the tropical Pacific in the preceding winter of 2014,the strength of the preceding instability was relatively weak. Weak oceanic eastward-propagating downwelling Kelvin waves were forced by the weak WWBs over the equatorial western Pacific in March 2014,as in February 1990. The consequent positive upper-oceanic heat content anomalies in the spring of 2014 induced only weak positive SSTAs in the central-eastern Pacific–unfavorable for the subsequent generation of summertime WWB sequences. Moreover,the equatorial western Pacific was not cooled,indicating the absence of positive Bjerknes feedback in early summer 2014. Therefore,the development of El Ni?o was suspended in summer 2014. | LI Jianying LIU Boqi LI Jiandong MAO Jiangyu | 2015 | Advances in Atmospheric Sciences2015，32，10： | 3 |
| 4 | Impact of tropical cyclone development on the instability of South Asian High and the summer monsoon onset over Bay of Bengal显示文摘 | Guoxiong Wu Suling Ren Jianmin Xu Dongxiao Wang Qing Bao Boqi Liu Yimin Liu | 2013 | Climate Dynamics (-)2013，，9： | 1 |
| 5 | Effects of monsoon onset vortex on heat budget in the mixed layer of the Bay of Bengal显示文摘We investigated the effects of monsoon onset vortex(MOV)on the mixed layer heat budget in the Bay of Bengal(BOB)in spring 2003 using the reanalysis datasets.The results suggest that the solar radiation flux penetrating the mixed layer and the existence of barrier layer are both able to modulate the effects of MOV on the evolution of sea surface temperature(SST)in the BOB.Prior to the formation of BOB MOV,the local SST raised quickly due to mass of solar radiation reaching the sea surface under the clear-sky condition.Meanwhile,since the mixed layer was shallow before the onset of the Asian summer monsoon(ASM),some solar radiation flux could penetrate to directly heat the deeper water,which partly offset the warming effect of shortwave radiation.On the other hand,the in-situ SST started to cool due to the upwelling of cold water when the MOV generated over the BOB,along with the rapidly increased surface wind speed and its resultant deeper mixed layer.As the MOV developed and moved northward,the SST tended to decrease remarkably because of the strong upward surface latent heat flux over the BOB ascribed to the wind-evaporation mechanism.However,the MOV-related precipitation brought more fresh water into the upper ocean to produce a thicker barrier layer,whose thermal barrier effect damped the cooling effect of entrainment upwelling on the decrease tendency of the BOB SST.In other words,the thermal barrier effect could slow down the decreasing trend of the BOB SST even after the onset of ASM,which facilitated the further enhancement of the MOV. | Effects of monsoon onset vortex on heat budget in the mixed layer of the Bay of BengalXU Kang LIU Boqi LIU Yu WANG Weiqiang HE Zhuoqi | 2020 | Journal of Oceanology and Limnology2020，38，6： | 1 |
| 6 | Expression and functional analysis of porcine aminopeptidase N produced in prokaryotic expression system 显示文摘 | Boqi Liu Guangxing Li Xiuwen Sui | 2009 | Journal of Biotechnology2009，141，： | 1 |
| 7 | Genetic susceptibility loci of lung cancer are associated with malignant risk of pulmonary nodules and improve malignancy diagnosis based on CEA levels显示文摘Objective:The heightened prevalence of pulmonary nodules(PN)has escalated its significance as a public health concern.While the precise identification of high-risk PN carriers for malignancy remains an ongoing challenge,genetic variants hold potentials as determinants of disease susceptibility that can aid in diagnosis.Yet,current understanding of the genetic loci associated with malignant PN(MPN)risk is limited.Methods:A frequency-matched case-control study was performed,comprising 247 MPN cases and 412 benign NP(BNP)controls.We genotyped 11 established susceptibility loci for lung cancer in a Chinese cohort.Loci associated with MPN risk were utilized to compute a polygenic risk score(PRS).This PRS was subsequently incorporated into the diagnostic evaluation of MPNs,with emphasis on serum tumor biomarkers.Results:Loci rs10429489G>A,rs17038564A>G,and rs12265047A>G were identified as being associated with an increased risk of MPNs.The PRS,formulated from the cumulative risk effects of these loci,correlated with the malignant risk of PNs in a dose-dependent fashion.A high PRS was found to amplify the MPN risk by 156%in comparison to a low PRS[odds ratio(OR)=2.56,95%confidence interval(95%CI),1.40−4.67].Notably,the PRS was observed to enhance the diagnostic accuracy of serum carcinoembryonic antigen(CEA)in distinguishing MPNs from BPNs,with diagnostic values rising from 0.716 to 0.861 across low-to high-PRS categories.Further bioinformatics investigations pinpointed rs10429489G>A as an expression quantitative trait locus.Conclusions:Loci rs10429489G>A,rs17038564A>G,and rs12265047A>G contribute to MPN risk and augment the diagnostic precision for MPNs based on serum CEA concentrations. | Zhi Li Liming Lu Yibin Deng Amei Zhuo Fengling Hu Wanwen Sun Guitian Huang Linyuan Liu Boqi Rao Jiachun Lu Lei Yang | 2023 | Chinese Journal of Cancer Research2023，35，5： | 0 |
| 8 | Soil Organic Carbon Sequestration Potential in Nectarine Orchards under Different Reclamation Systems显示文摘The Red Soil Hilly Region in South China, where there is a high capacity of carbon(C), and the land use and vegetation cover change greatly, is an important ecological area in the world, and has an important impact on the global carbon cycle and the seasonal fluctuation of atmospheric CO_2. To better evaluate the effects of reclamation systems in orchards converted from grasslands on soil carbon sequestration, we investigated soil organic carbon(SOC) content and stable C isotope(δ^(13)C)composition in three nectarine orchards at Yuchi Experimental Station in South China. Compared with the sloping clean tillage orchard and terraced clean tillage orchard, SOC content in the terraced orchard with grass cover was increased by 14.90% to 38.49%, and 7.40% to 15.33%, respectively. During the 14 years after orchard establishment, the soil organic matter sources influenced both δ^(13)C distribution with depth and carbon replacement. SOC turnover of the upper soil layer in the terraced orchard with grass cover(a mean 63.05% of replacement in the 20 cm after 14 years) was 1.59 and 1.41 times larger than that of the sloping clean tillage orchard and terraced clean tillage orchard under subtropical conditions, respectively. The equilibrium value of soil organic carbon in the three treatments ranged from 16.067 to 25.608 g/kg under the experimental conditions. The equilibrium value of soil organic carbon in the surface layer under grass cover was 54.801 t/hm^2, and the carbon sequestration potential was 24.695 1 t/hm^2. | Yixiang WANG Boqi WENG Jing YE Chengji WANG Cenwei LIU Yanchun LI | 2017 | Agricultural Science & Technology2017，18，7： | 0 |
| 9 | Assessing the contribution of global wildfire biomass burning to BaP contamination in the Arctic显示文摘Polycyclic aromatic hydrocarbons(PAHs)have become cause for growing concern in the Arctic ecosystems,partly due to their stable levels despite global emission reduction.Wildfire is considered one of the primary sources that influence PAH levels and trends in the Arctic,but quantitative investigations of this influence are still lacking.This study estimates the global emissions of benzo[a]pyrene(BaP),a congener of PAHs with high carcinogenicity,from forest and grassland fires from 2001 to 2020 and simulates the contributions of wildfire-induced BaP emissions from different source regions to BaP contamination in the Arctic.We find that global wildfires contributed 29.3%to annual averaging BaP concentrations in the Arctic from 2001 to 2020.Additionally,we show that wildfires contributed significantly to BaP concentrations in the Arctic after 2011,enhancing it from 10.1%in 2011 to 83.9%in 2020.Our results reveal that wildfires accounted for 94.2%and 50.8%of BaP levels in the Asian Arctic during boreal summer and autumn,respectively,and 74.2%and 14.5%in the North American Arctic for the same seasons.The source-tagging approach identified that local wildfire biomass emissions were the largest source of BaP in the Arctic,accounting for 65.7%of its concentration,followed by those of Northern Asia(17.8%)and Northern North America(13.7%).Our findings anticipate wildfires to play a larger role in Arctic PAH contaminations alongside continually decreasing anthropogenic emissions and climate warming in the future. | Shijie Song Boqi Chen Tao Huang Shuxin Ma Luqian Liu Jinmu Luo Huizhong Shen Jiaxin Wang Liang Guo Min Wu Xiaoxuan Mao Yuan Zhao Hong Gao Jianmin Ma | 2023 | Environmental Science and Ecotechnology2023，，2： | 0 |
| 10 | Retractosomes:small extracellular vesicles generated from broken-off retraction fibers显示文摘Dear Editor,Various cell protrusions are known to generate extracellular vesicles.A migratory cell generates retractionfibers(RFs)and migrasomes during migration.After the cell migrates away,large amounts of RFs breakoff from the cell and areleftbehind.The fateof RFs afterdetaching from cells is currently unknown.To investigatethefateof RFs,weobservedTspan4-overexpressing L929 cells with live-cell imaging(Supplementary information,Data S1).We found that during migration,RFs are pulled out at the trailingedgeofcells,andmigrasomes soonformonthetipsor branch points of the RFs.At this stage,the Tspan4 signal is evenly distributed along the RFs(Fig.1a).Eventually,the RFs start to break.Inmostcases,thesectionsof RFfarawayfromthecells break first,which is not surprising,as these sectionsof RFare formed earlier.Interestingly,after the RFsbreak up,the Tspan4 signal appears as a large number of small puncta along the paths which were occupied by the RFs(Fig.1a;Supplementary information,Video S1). | Yizheng Wang Shuaixin Gao Yuheng Liu Dongju Wang Boqi Liu Dong Jiang Catherine C.L.Wong Yang Chen Li Yu | 2022 | Cell Research2022，32，10： | 0 |
| 11 | Progress and Prospects of Research on Subseasonal to Seasonal Variability and Prediction of the East Asian Monsoon显示文摘Subseasonal to seasonal(S2S)variability represents the atmospheric disturbance on the 10–90-day timescale,which is an important bridge linking weather and climate.In 2015,China Meteorological Administration(CMA)listed the S2S prediction project that was initiated by WMO programs three years ago as one of its key tasks.After five years of research,significant progress has been made on the mechanisms of the East Asian monsoon(EAM)S2S variability,related impact of climate change,as well as the predictability on the S2S timescale of numerical models.The S2S variability of the EAM is closely linked to extreme persistent climate events in China and is an important target for seasonal climate prediction.However,under the influence of global warming and the interactions among climate systems,the S2S variability of the EAM is so complex that its prediction remains a great challenge.This paper reviews the past achievement and summarizes the recent progress in research of the EAM S2S variability and prediction,including characteristics of the main S2S modes of the EAM,their impact on the extreme events in China,effects of external and internal forcing on the S2S variability,as well as uncertainties of climate models in predicting the S2S variability,with a focus on the progress achieved by the S2S research team of the Chinese Academy of Meteorological Sciences.The present bottlenecks,future directions,and critical research recommendations are also analyzed and presented. | Congwen ZHU Boqi LIU Lun LI Shuangmei MA Ning JIANG Yuhan YAN | 2022 | Journal of Meteorological Research2022，36，5： | 0 |
| 12 | Organocatalytic asymmetric [3+3] annulation of isatin N,N’-cyclic azomethine imines with enals:Efficient approach to functionalized spiro N-heterocyclic oxindoles显示文摘An unprecedented chiral secondary amine-catalyzed [3+3] annulation of isatin N,N’-cyclic azomethine imines with α,β-unsaturated aldehydes was developed.This strategy allowed the construction of structurally novel spiro N-heterocyclic oxindole derivatives in good yields(up to 91%) and good to excellent enantioselectivities(up to>99% ee),albeit with modest diastereoselectivities(up to 3.1:1 dr). | Boqi Gu Shuxiao Wu Hui Xu Wulin Yang Zhixiang Liu Weiping Deng | 2021 | Chinese Chemical Letters2021，32，2： | 0 |
| 13 | Diversity of the Coupling Wheels in the East Asian Summer Monsoon on the Interannual Time Scale: Challenge of Summer Rainfall Forecasting in China显示文摘Two types of three-dimensional circulation of the East Asian summer monsoon(EASM) act as the coupling wheels determining the seasonal rainfall anomalies in China during 1979–2015. The first coupling mode features the interaction between the Mongolian cyclone over North Asia and the South Asian high(SAH) anomalies over the Tibetan Plateau at 200 hPa. The second mode presents the coupling between the anomalous low-level western Pacific anticyclone and upperlevel SAH via the meridional flow over Southeast Asia. These two modes are responsible for the summer rainfall anomalies over China in 24 and 7 out of 37 years, respectively. However, the dominant SST anomalies in the tropical Pacific, the Indian Ocean, and the North Atlantic Ocean fail to account for the first coupling wheel's interannual variability, illustrating the challenges in forecasting summer rainfall over China. | Congwen ZHU Boqi LIU Kang XU Ning JIANG Kai LIU | 2021 | Advances in Atmospheric Sciences2021，38，4： | 0 |
| 14 | Moment-tensor inversion and decomposition for cracks in thin plates显示文摘The knowledge of crack type and dislocation orientation is helpful for the lifetime prediction of thin plates on aircrafts.The moment-tensor inversion utilizes the Acoustic Emission(AE)signals to detect cracks and the source mechanisms can be interpreted by the decomposition of moment tensors.Since the traditional moment-tensor inversion is implemented for the AE sources inside infinite elastic bodies,the inversion needs to be modified for the cracks in thin plates.In this study,the moment tensors of cracks in thin plates are derived and the inversion equation is provided based on the Green's function of second kind.A method of modifying the moment tensors to adapt to the existing decomposition processes and source-type plots is provided.By employing the Finite Element Method(FEM),the wave fields generated by the AE sources are computed.The AE sources continuously changing from pure tensile type(Model I)to shear type(Model II)are achieved in the FE models and the moment tensors are recovered.By the comparison between the reference values and recovered solutions,the source type can be accurately identified in the source-type plot and the applicability of the moment-tensor inversion for cracks in thin plates is confirmed. | Yue KONG Min LI Weimin CHEN Ning LIU Boqi KANG | 2021 | Chinese Journal of Aeronautics2021，34，4： | 0 |
| 15 | The phosphatidylinositol(4,5)-bisphosphate-Rab35 axis regulates migrasome formation显示文摘Migrasomes are recently discovered organelles,which are formed on the ends or branch points of retraction fibers at the trailing edge of migrating cells.Previously,we showed that recruitment of integrins to the site of migrasome formation is essential for migrasome biogenesis.In this study,we found that prior to migrasome formation,PIP5K1A,a PI4P kinase which converts PI4P into PI(4,5)P_(2),is recruited to migrasome formation sites.The recruitment of PIP5K1A results in generation of PI(4,5)P_(2) at the migrasome formation site.Once accumulated,PI(4,5)P_(2) recruits Rab35 to the migrasome formation site by interacting with the C-terminal polybasic cluster of Rab35.We further demonstrated that active Rab35 promotes migrasome formation by recruiting and concentrating integrinα5 at migrasome formation sites,which is likely mediated by the interaction between integrinα5 and Rab35.Our study identifies the upstream signaling events orchestrating migrasome biogenesis. | Tianlun Ding Jinyao Ji Weiying Zhang Yuheng Liu Boqi Liu Yiyang Han Chunlai Chen Li Yu | 2023 | Cell Research2023，33，8： | 0 |
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