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| 1 | Future of liver disease in the era of direct acting antivirals for the treatment of hepatitis C显示文摘Hepatitis C virus(HCV) infection has been a global health problem for decades, due to the high number of infected people and to the lack of effective and welltolerated therapies. In the last 3 years, the approval of new direct acting antivirals characterized by high rates of virological clearance and excellent tolerability has dramatically improved HCV infection curability, especially for patients with advanced liver disease and for liver transplant recipients. Long-term data about the impact of the new direct acting antivirals on liver fibrosis and liver disease-related outcomes are not yet available, due to their recent introduction. However, previously published data deriving from the use of pegylatedinterferon and ribavirin lead to hypothesizing that we are going to observe, in the future, a reduction in mortality and in the incidence of hepatocellular carcinoma, as well as a regression of fibrosis for people previously affected by hepatitis C. In the liver transplant setting, clinical improvement has already been described after treatment with the new direct acting antivirals, which has often led to patients delisting. In the future, this may hopefully reduce the gap between liver organ request and availability, probably expanding liver transplant indications to other clinical conditions. Therefore, these new drugs are going to change the natural history of HCV-related liver disease and the epidemiology of HCV infection worldwide. However, the global consequences will depend on treatment accessibility and on the number of countries that could afford the use of the new direct acting antivirals. | Francesca Romana Ponziani Francesca Mangiola Cecilia Binda Maria Assunta Zocco Massimo Siciliano Antonio Grieco Gian Lodovico Rapaccini Maurizio Pompili Antonio Gasbarrini | 2017 | World Journal of Hepatology2017，9，7： | 3 |
| 2 | Results, Outcome Predictors, and Complications after Stapled Transanal Rectal Resection for Obstructed Defecation显示文摘 | Giuseppe Gagliardi M.D. Mario Pescatori M.D. F.R.C.S. E.B.S.Q. Donato F. Altomare M.D. Gian Andrea Binda M.D. Corrado Bottini M.D. Giuseppe Dodi M.D. Vincenzino Filingeri M.D. Giovanni Milito M.D. Marcella Rinaldi M.D. Giovanni Romano M.D. Liana Spazzaf | 2008 | Diseases of the Colon & Rectum2008，，2： | 2 |
| 3 | Standard laparoscopic versus single-incision laparoscopic colectomy for cancer: early results of a randomized prospective study显示文摘 | Cristiano G. Huscher Andrea Mingoli Giovanna Sgarzini Andrea Mereu Barbara Binda Gioia Brachini Silvia Trombetta | 2012 | The American Journal of Surgery2012，，1： | 2 |
| 4 | Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma 显示文摘 | Galli R Binda E Orfanelli U | 2004 | Cancer Reg2004，64，19： | 1 |
| 5 | Multicity Italianstudy of congenital cytomegalovirus infection显示文摘 | Barbi M Binda S Caroppo S | 2006 | Pediatr Infect Dis J2006，25，2： | 1 |
| 6 | Isolation and characterization of tumorigenic,stem-like neural precursors from human glioblastoma显示文摘 | Galli R Binda E Orfanelli U | 2004 | Cancer Res2004，64，19： | 1 |
| 7 | CytomegalovirusDNA de2tection in Guthrie cards: apowerful tool for diagnosing congenital 显示文摘 | BarbiM Binda S Primache V | 2000 | infectionl J Clin Virol2000，17，： | 1 |
| 8 | Hepatitis B vires surface antigen impair myeloid dendritic cell function:a possible immune escape mechanism of hepatitis B virus 显示文摘 | Op den Brouw ML Binda RS VanRoosmalen MH | 2009 | Immunology2009，126，2： | 1 |
| 9 | Radiosensitization of human melanoma cells by ribozyme-mediated inhibition of survivin expression显示文摘 | Pennati M Binda M | 2003 | J Invest Dermatol2003，120，4： | 1 |
| 10 | Role of Vascular endothelial growth factor receptor 1 in basal adhesion formation and in carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in mice 显示文摘 | Molinas CR Binda MM Carmeliet P | 2004 | Fertil Steril2004，82，： | 1 |
| 11 | Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders显示文摘 | Binda C Newton-Vinson P Hubalek F | 2002 | Nat Struct Biol2002，9，1： | 1 |
| 12 | Long-term outcome of Altemeier's procedure for rectal prolapse显示文摘 | Ahomare DF Binda G Ganio E | 2009 | Dis Colon Rectum2009，52，： | 1 |
| 13 | Isolation and characterization of tumorigenic,stem like neural precursors from human glioblastoma显示文摘 | Galli R Binda E Orfanelli U | 2004 | Cancer Res2004，64，19： | 1 |
| 14 | Functional impairment of myeloid and plamacytoid dendritic cells of patients with chronic hepatitis B显示文摘 | Van fer Molen RG Sprengers D Binda RS | 2004 | Hepatology2004，40，： | 1 |
| 15 | Diagnosis of congenital CMV infection via dried blood spots 显示文摘 | Barbi M Binda S Caroppo S | 2006 | Rev Med Virol2006，16，： | 1 |
| 16 | Isolation and charac- terization of tumorigenic, stem-like neural precursors from human glioblastoma显示文摘 | Galli R Binda E Orfanelli U | 2004 | Cancer Res2004，64，19： | 1 |
| 17 | Isolation and charaeterization of tumorigenic,stem-like neural precursors from human glioblastoma显示文摘 | Galli R Binda E Orfanelli U | 2004 | Cancer Res2004，64，19： | 1 |
| 18 | Cytomegalovirus DNA detection in Guthrie cards : a powerful tool for diagnosing congenital infection显示文摘 | Barbi M Binda S Primache V | 2000 | J Clin Virol2000，17，： | 1 |
| 19 | Long-term outcome ofAltemeier' s procedure for rectal prolapse 显示文摘 | Altomare DF Binda G Ganio E | 2009 | Dis ColonRectum2009，52，： | 1 |
| 20 | Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma 显示文摘 | Galli R Binda E Orfanelli U | 2004 | Cancer Res2004，64，19： | 1 |
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