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| 1 | Outcomes of Medicare beneficiaries hospitalised with transient ischaemic attack and stratification using the ABCD^(2) score显示文摘Background Long-term outcomes for Medicare beneficiaries hospitalised with transient ischaemic attack(TIA)and role of ABCD^(2) score in identifying high-risk individuals are not studied.Methods We identified 40825 Medicare beneficiaries hospitalised from 2011 to 2014 for a TIA to a Get With The Guidelines(GWTG)-Stroke hospital and classified them using ABCD^(2)s of mortality and rehospitalisation(all-cause,ischaemic stroke,haemorrhagic stroke,myocardial infarction,and gastrointestinal and intracranial haemorrhage)for high-risk versus low-risk groups adjusted for patient and hospital characteristics.Results Of the 40825 patients,35118(86%)were high risk(ABCD^(2)≥4)and 5707(14%)were low risk(ABCD^(2)=0-3).Overall rate of mortality during 1-year follow-up after hospital discharge for the index TIA was 11.7%,44.3% were rehospitalised for any reason and 3.6%were readmitted due to stroke.Patients with ABCD^(2) score≥4 had higher mortality at 1 year than not(adjusted HR 1.18,95%CI 1.07 to 1.30).Adjusted risks for ischaemic stroke,all-cause readmission and mortality/all-cause readmission at 1 year were also significantly higher for patients with ABCD^(2) score≥4 vs 0-3.In contrast,haemorrhagic stroke,myocardial infarction,gastrointestinal bleeding and intracranial haemorrhage risk were not significantly different by ABCD^(2) score.Conclusions This study validates the use of ABCD^(2) score for long-term risk assessment after TIA in patients aged 65 years and older.Attentive efforts for community-based follow-up care after TIA are needed for ongoing prevention in Medicare beneficiaries who were hospitalised for TIA. | Shreyansh Shah Li Liang Durgesh Bhandary Saga Johansson Eric E Smith Deepak L Bhatt Gregg C Fonarow Naeem D Khan Eric Peterson Janet Prvu Bettger | 2021 | Stroke & Vascular Neurology2021，6，2： | 3 |
| 2 | Emergency medical services use and its association with acute ischaemic stroke evaluation and treatment in Singapore显示文摘Background Emergency medical services(EMS)is a critical link in the chain of stroke survival.We aimed to assess EMS use for stroke in Singapore,identify characteristics associated with EMS use and the association of EMS use with stroke evaluation and treatment.Methods The Singapore Stroke Registry combines nationwide EMS and public hospital data for stroke cases in Singapore.Multivariate regressions with the generalised estimating equations were performed to examine the association between EMS use and timely stroke evaluation and treatment.results Of 3555 acute ischaemic patients with symptom onset within 24 hours admitted to all five public hospitals between 2015 and 2016,68%arrived via EMS.Patients who used EMS were older,were less likely to be female,had higher stroke severity by National Institute of Health Stroke Scale and had a higher prevalence of atrial fibrillation or peripheral arterial disease.Patients transported by EMS were more likely to receive rapid evaluation(door-to imaging time≤25 min 34.3%vs 11.1%,OR=2.74(95%CI 1.40 to 5.38))and were more likely to receive intravenous tissue plasminogen activator(tPA,22.8%vs 4.6%,OR=4.61(95%CI 3.52 to 6.03)).Among patients treated with tPA,patients who arrived via EMS were more likely to receive timely treatment than self-transported patients(door-to needle time≤60 min 52.6%vs 29.4%,OR=2.58(95%CI 1.35 to 4.92)).Conclusions EMS use is associated with timely stroke evaluation and treatment in Singapore.Seamless EMS-Hospital stroke pathways and targeted public campaigns to advocate for appropriate EMS use have the potential to improve acute stroke care. | Hanzhang Xu Ying Xian Fung Peng Woon Janet Prvu Bettger Daniel T Laskowitz Yih Yng Ng Marcus Eng Hock Ong David Bruce Matchar Deidre Anne De Silva | 2020 | Stroke & Vascular Neurology2020，5，2： | 2 |
| 3 | Effect of dietary zinc or copper deficiency on the primary free radical defense system in rats显示文摘 | Taylor CG Bettger WJ Bray TM | 1988 | J Nutr1988，118，： | 2 |
| 4 | A randomized,controlled parallel-group trial on efficacy and safety of iron sucrose(Venofer)vs iron gluconate(Ferrlecit)in haemodialysis patients treated with rHuEpo显示文摘 | Kosch M Bahner U Bettger H | 2001 | Nephrol Dial Transplant2001，16，6： | 1 |
| 5 | Factors influencing morbidity and mortatlity after pancreaticcoduodenectomy: Critical analysis of 221 resection显示文摘 | Bettger T C Junginger T | 1999 | World J Surg1999，23，2： | 1 |
| 6 | Effect of zinc and copper deficiency on microsomal NADPH dependent active oxigen generation in rat liver and lung显示文摘 | Ammermuller J D Bray T M Bettger W J | 1987 | Journal of Nutrition1987，111，： | 1 |
| 7 | The physiological role of zinc :s an antioxidant显示文摘 | Bray T M Bettger W J | 1990 | Free Radical Biology and Medicine1990，，8： | 1 |
| 8 | The nutrient requirements of cultured mammalian cells显示文摘 | Bettger W J Ham R G | 1982 | Adv Nutr Res1982，4，： | 1 |
| 9 | A randomized, controlled parallel-group trial on efficacy and safety of iron sucrose (Venofer) vs iron gluconate (Ferrlecit) in haemodialysis patients treated with rHuEPO显示文摘 | Kosch M Bahner U Bettger H | 2001 | Neph- rol Dial Transplant2001，16，6： | 1 |
| 10 | A Critical Physiological role of Zinc in the Structure and function of biomembranes显示文摘 | Bettger W J odell BL | 1981 | Life Sci1981，28，13： | 1 |
| 11 | Physiological roles of zinc in the plasma membrane of mammalian cells 显示文摘 | Bettger W J O' Dell B L | 1993 | J Nutr Biochem1993，14，： | 1 |
| 12 | A randomized,controlled parallel group trial on efficacy and safety of iron sucrose(Venofer)vsirongluconate (Ferrlecit) in haemodialysis patients treated with rHuEPO显示文摘 | Kosch M BaNner U Bettger H | | 0，，6： | 1 |
| 13 | Effect of zinc and copper deficiency on microsomal NADPH dependent active oxigen generation in rat liver and lung显示文摘 | Ammermuller J D Bray T M Bettger W J | 1987 | Journal of Nutrition1987，111，： | 1 |
| 14 | Physiological roles of zinc in the plasma membrane of mammalian cells显示文摘 | BETTGER W J O'DELL B L | 1993 | Journal of Nutritional Biochemistry1993，4，4： | 1 |
| 15 | Three-year follow-up on the IVIg for Alzheimer′s phase II study显示文摘 | Relkin N Bettger L Tsakanikas D | 2012 | Alzheimer′s Dement2012，，： | 1 |
| 16 | Transitional care after hospitalization for acute stroke or myocardial infarction:a systematic review显示文摘 | Prvu Bettger J A1exander KP Dolor RJ | 2012 | Ann Intern Med2012，157，： | 1 |
| 17 | Effects of dietary zinc dificiency and the associated drop in voluntary food intake on rat erythrocyte membrane polyamines显示文摘 | Avery R A Bettger W J | 1988 | J Nutr1988，118，8： | 1 |
| 18 | A critical physioIogical role of zinc in the structure and function of biomembranes 显示文摘 | BETTGER W J O'DELL B L | 1981 | Life Sci1981，28，13： | 1 |
| 19 | A critical physiological role of zinc in the structure and function of biomembranes显示文摘 | BETTGER W J O'DELL B L | 1981 | Life Sciences1981，28，13： | 1 |
| 20 | Modality of language shapes working memory: Evidence from digit span and spatial span in asl signers显示文摘 | Wilson M Bettger J Nieulae I | 1997 | J Deaf Stud Deaf Educ1997，2，3： | 1 |
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