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| 1 | Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno-or squamous cell carcinoma显示文摘AIM:To determine whether-1195 A→G and/or-765 G→C polymorphisms in Cyclooxygenase-2(COX-2 ) may have a risk modifying effect on the development of esophageal carcinoma in a Dutch Caucasian population.METHODS:Two study groups were recruited, 252 patients with esophageal carcinoma and 240 healthy controls, matched for race, age, gender and recruiting area.DNA was isolated from whole blood and used for genotyping.PCR products were digested with restriction enzymes and products were analyzed by agarose gel electrophoresis.Odds ratios(OR) and 95% confldence intervals(CI) were estimated.RESULTS:The distribution of the-1195 A→G polymorphism was signif icantly different in esophageal cancer patients compared to controls.The-1195 GG genotype resulted in a higher risk of developing esophageal adenocarcinoma(OR = 3.85, 95% CI:1.45-10.3) compared with the-1195 AA genotype as a reference.The-765 G→C genotype distribution was not different between the two groups.The GG/ GG haplotype was present more often in esophageal adenocarcinoma patients than in controls(OR = 3.45, 95% CI:1.24-9.58;with AG/AG as a reference).The same trends were observed in patients with squamous cell carcinomas, however, the results did not reach statistical signif icance.CONCLUSION:Presence of the COX-2-1195 GG genotype and of the GG/GG haplotype may result in a higher risk of developing esophageal carcinoma. | Jón O Kristinsson Paul van Westerveld Rene HM te Morsche Hennie MJ Roelofs T Wobbes Ben JM Witteman Adriaan CITL Tan Martijn GH van Oijen Jan BMJ Jansen Wilbert HM Peters | 2009 | World Journal of Gastroenterology2009，15，28： | 11 |
| 2 | 一种基于数据挖掘的GIS及在航海中的应用显示文摘根据聚类分析方法中密度凝聚的思想 ,提出一种新的复合聚类分析算法 ,进一步将这种算法用于地理信息系统的数据挖掘 ,并应用于船舶航线的自动设计。 | 王天真 郝瑞吉 汤天浩 Ben■t MOMEUX Lionel HAMEL Guillaume EUDELINE | 2003 | 中国航海2003，26，3： | 5 |
| 3 | Benefits of the use of blood conservation in scoliosis surgery显示文摘AIM To investigate whether autologous blood transfusion(ABT) drains and intra-operative cell salvage reduced donor blood transfusion requirements during scoliosis surgery.METHODS Retrospective data collection on transfusion requirements of patients undergoing scoliosis surgery is between January 2006 and March 2010. There were three distinct phases of transfusion practice over this time: Group A received 'traditional treatment' with allogeneic red cell transfusion(ARCT) in response to an intra- or postoperative anaemia(Hb < 8 g/d L or a symptomatic anaemia); Group B received intra-operative cell salvage in addition to 'traditional treatment'. In group C,ABT wound drains were used together with both intra-operative cell salvage and 'traditional treatment'.RESULTS Data from 97 procedures on 77 patients,there was no difference in mean preoperative haemoglobin levels between the groups(A: 13.1 g/d L; B: 13.49 g/d L; C: 13.66 g/d L). Allogeneic red cell transfusion was required for 22 of the 37 procedures(59%) in group A,17 of 30(57%) in group B and 16 of 30(53%) in group C. There was an overall 6% reduction in the proportion of patients requiring an ARCT between groups A and C but this was not statistically significant(χ2 = 0.398). Patientsin group C received fewer units(mean 2.19) than group B(mean 2.94)(P = 0.984) and significantly fewer than those in group A(mean 3.82)(P = 0.0322). Mean length of inpatient stay was lower in group C(8.65 d) than in groups B(12.83) or A(12.62).CONCLUSION When used alongside measures to minimise blood loss during surgery,ABT drains and intra-operative cell salvage leads to a reduced need for donor blood transfusion in patients undergoing scoliosis surgery. | Peter R Loughenbury Lyeanda Berry Ben T Brooke Abhay S Rao Robert A Dunsmuir Peter A Millner | 2016 | World Journal of Orthopedics2016，7，12： | 3 |
| 4 | Carbonation of calcium-containing mineral and industrial by-products显示文摘The use of carbon dioxide(CO_(2))and calciumcontaining by-products from industrial activities is receiving increasing interest as a route to valuable carbonate materials while reducing CO_(2) emissions and saving natural resources.In this work,wet-chemical experimental data was assessed,which involved the carbonation of three types of materials in aqueous solutions,namely,1)wollastonite,a calcium silicate mineral,2)steelmaking slag,a by-product of steel production,and 3)paper bottom ash(PBA)from waste paper incineration.Aims were to achieve either a high carbonation degree and/or a pure carbonate product with potential commercial value.Producing a pure precipitated calcium carbonate(PCC)material that may find use in paper industry products puts strong requirements on purity and brightness.The parameters investigated were particle size,CO_(2)pressure,temperature,solid/liquid ratio,and the use of additives that affect the solubilities of CO_(2)and/or calcium carbonate.Temperatures and pressures were varied up to 180℃and 4 MPa.Data obtained with the wollastinite mineral allowed for a comparison between natural resources and the industrial by-product materials,the latter typically being more reactive.With respect to temperature and pressure trends reported by others were largely confirmed,with temperatures above 150℃introducing thermodynamic limitations depending on CO_(2)pressure.The influence of additives showed some promise,although costs may make recycling and reuse of additives a necessity for a largescale process.When using steelmaking slag,magnetic separation may remove some iron-containing material from the process(although this is far from perfect),while the addition of bicarbonate supported the removal of phosphorous,aside from improving calcium extraction.The experiments with paper bottom ash(PBA)gave new data,showing that its reactivity resembles that of steelmaking slag,while its composition results in relatively pure carbonate product.Also,with PBA no additives were needed to achieve this. | Ron ZEVENHOVEN Anders WIKLUND Johan FAGERLUND Sanni ELONEVA Ben IN’T VEEN Hans GEERLINGS Gert VAN MOSSEL Harold BOERRIGTER | 2010 | Frontiers of Chemical Science and Engineering2010，4，2： | 2 |
| 5 | Effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease: an updated systematic review and meta-analysis显示文摘 | Sophie A Jamal Ben Vandermeer Paolo Raggi David C Mendelssohn Trish Chatterley Marlene Dorgan Charmaine E Lok David Fitchett Ross T Tsuyuki | 2013 | The Lancet2013，，： | 2 |
| 6 | PPARα and PPARδ activators inhibit cytokine-induced nuclear translocation of NF-κB and expression of VCAM-1 in EAhy926 endothelial cells显示文摘 | Rival Y Benéteau N Taillandier T | 2002 | European Journal Pharmacology2002，435，8： | 2 |
| 7 | 生物炭在柑橘皮厌氧发酵中作用机理研究显示文摘该研究主要调查柑橘皮废料厌氧消化能力在不同类型的生物炭和不同比率下的影响。柑橘皮对厌氧消化有抑制作用。生物炭的存在有两种影响:相对于只有柑橘皮废料的培养来说,它减少了迟滞期的长度,并且使甲烷的产量更高。微生物迟滞期随着柑橘皮与生物炭比例的增加而降低,在比例为2∶1时停滞期最长,为9.4 d,在比例为1∶3时迟滞期最短,为7.5 d。生物炭和柑橘皮培养中累积的甲烷产量在163.9到186.8 mLCH4 ·g^-1VS之间变动,而只有柑橘皮培养中的甲烷产量只有165.9 mLCH4 ·g^-1VS。在检测生物炭材料时发现了推测的产甲烷菌群。D-柠檬烯吸附和微生物固定化的协同作用在生物炭的影响下会提高厌氧消化的性能。 | Michael O Fagbohungbe Ben M J Herbert Lois Hurst Hong Li Shams Q Usmani Kirk T Semple 张冀川(译) | 2019 | 中国沼气2019，37，5： | 2 |
| 8 | Radiolarian and Planktic Foraminifera Biostratigraphy of the Early Albian Organic Rich Beds of Fahdene Formation,Northern Tunisia显示文摘The lower part of Fahdene Formation outcropping in northeastern Tunisia is represented by pelagic sequences and characterized by an important siliciclastic fraction that includes radiolarian and organic-rich beds of Allam Member.?Litho-biostratigraphic analysis based on planktic foraminifera and radiolaria shows that deposition of organic-rich beds of Allam Member is confined to the Microhedbergella rischi Zone through the lower part of Ticinella primula Zone.?Age diagnostic radiolaria recovered from these beds has been identified to constrain a direct age of black shale deposition.The assemblages can be correlated with the radiolarian biochronozone U.A.10–11 indicating an Early Albian to early Middle Albian in age.Radiolarian assemblages composed of species characteristic of U.A.10 biochronozone(A.montisserei,D.gracilis)are associated with radiolarian taxa belonging to Costata Zone(U.A.9 Pseudoeucyrtis hanni and Thanarla pseudodecora),which can be correlated with Dercourt Member in the Ionian Zone and Paquier level of the Vocontian Basin(southeast of France).Biostratigraphic and abundance curves analysis has demonstrated significant diversification of cryptocephalic Nassellaria and Archaeodictyomitrae,probably adapted to eutrophic conditions that characterized the Aptian-Albian transition.Ecological conditions may have governed the stratigraphic range of many cosmopolitan taxa(i.e.,Pseudodictyomitrae lodogaensis)compared with stratigraphic distributions schemes reported from other domains.The timing of black shales deposition was diachronic due to local geodynamic conditions and upwelling currents distribution.The Allam black shales are correlative with the oceanic anoxic event OAE1b which is characterized by the widespread of supraregionnally organic-rich beds in the Mediterranean Tethys basins across the Aptian-Albian transition. | M Ben Fadhel T Zouaghi A Amri M Ben Youssef | 2014 | Journal of Earth Science2014，25，1： | 2 |
| 9 | Use of Genetic Algorithms for Neural Networks to Predict Community-acquired Pneumonia显示文摘 | Paul S H Ben S G Thomas G T | 2004 | Artificial Intelligence in Medicine2004，30，： | 1 |
| 10 | Sorption and mobility of pharmaceutical compounds in soil1 irrigated with reclaimed wastewater 显示文摘 | Chefetz B Mualem T Ben - Ari J | 2008 | Chemosphere2008，73，： | 1 |
| 11 | Increased antifungal activity of Tfichoderma harzianum transformants that overexpress a 33-kDa chitinase显示文摘 | Limon M C Pintor-Toro J A Benítez T | 1999 | Phytopathol1999，89，： | 1 |
| 12 | Hydrosulphide complexing of Au (Ⅰ)in hydrothermal solutions from 150-400℃ and 500-1500 bar显示文摘 | Benning L G Seward T M | 1996 | Geochimica et Cosmochimica Acta1996，60，11： | 1 |
| 13 | Factors related to unstained areas in whole ewe ovaries perfused with a metabolic marker显示文摘 | TORRE A BEN BRAHIM F POPOWSKI T | 2013 | Hum Reprod2013，28，2： | 1 |
| 14 | Bioplastic production usingwood mill effluents as feedstock 显示文摘 | Ben M Mato T Lopez A | 2011 | Water Science andTechnology2011，63，6： | 1 |
| 15 | Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study显示文摘 | Ben R Naimath K Eray T | 2003 | Neurol Res2003，25，1： | 1 |
| 16 | Distribution of substituents in carboxymethyl ethers of cyclomaltoheptaose 显示文摘 | Ben J R Rao C T Pitjha J1 | 1994 | Carbohydrate research1994，258，： | 1 |
| 17 | Targeted synthesis of a porous aromatic framework with high stability and excep- tionally high surface area显示文摘 | BEN T REN H MA S Q | 2009 | Angew Chem Int Ed2009，121，50： | 1 |
| 18 | The changing face of neural stem cell therapy in neurologic diseases 显示文摘 | Einstein O Ben - Hur T | 2008 | Arch Neurol2008，65，4： | 1 |
| 19 | A model experiment forelucidating the mechanism of astringency removal in persimmonfruit using respiratin inhibitors显示文摘 | MATSUO T ITOO S BEN ARIE R | 1991 | Jpn Soc Hor Sci1991，60，2： | 1 |
| 20 | The schneiderian membrane contains osteoprogenitor cells: in vivo and in vitro study 显示文摘 | Srouji S Kizhner T Ben David D | 2009 | Calcif Tissue Int2009，84，2： | 1 |
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