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| 1 | 局部和全身给药后泼尼松龙在外淋巴液中的浓度分析显示文摘目的 :比较局部和全身给药后 2 1 氢化琥珀酸 泼尼松龙在外淋巴液中的药物动力学。方法 :将实验豚鼠分组 ,局部用药 (局部组 ) :将 0 .5 %的 2 1 氢化琥珀酸 泼尼松龙液在直视下置于圆窗龛 ;全身用药 (全身组 ) :按 6 0mg/kg腹腔内注药 ;两组均以生理盐水作为对照。分别于给药后不同时间段采集外淋巴液标本 ,采用高压液相色谱法 (HPLC)测定药物浓度。结果 :局部组药物最高浓度出现在给药后 180min ,为 (95 2 .3± 382 .7)mg/L ,并在 96 0min后维持在 (18.72± 16 .97)mg/L。全身组药物最高峰时间在给药后 15 0min ,为 (14 .71± 7.0 5 )mg/L。结论 :局部给予 2 1 氢化琥珀酸 泼尼松龙 ,可以获得长时间、高浓度的药物水平。 | 苏纪平 Bachmann G 唐安洲 Zumegen C Michel O Wittekindt C | 2003 | 临床耳鼻咽喉科杂志2003，17，10： | 16 |
| 2 | EZH2 Expression Is Associated With High Proliferation Rate and Aggressive Tumor Subgroups in Cutaneous Melanoma and Cancers of the Endometri- um, Prostate, and Breast 显示文摘 | Bachmann 1 M Halvorsen O J Collett K | 2006 | Journal of Clinical Oncology2006，24，2： | 1 |
| 3 | Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients显示文摘 | Reich O Gratzke C Bachmann A | 2008 | J Urol2008，180，： | 1 |
| 4 | Relalionships between HIV/ AIDS, income and expenditure over time in deprived South African households显示文摘 | Bachmann M O Booysen F L R | 2004 | AIDS care2004，16，7： | 1 |
| 5 | EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melano- ma and cancers of the endometrium, prostate, and breast显示文摘 | Bachmann I M Halvorsen O J Collett K | 2006 | J Clin Oncol2006，24，2： | 1 |
| 6 | Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective muhieenter evaluation of 10,654 patients显示文摘 | Reich O Gratzke C Bachmann A | 2008 | J Urol2008，1800，： | 1 |
| 7 | Importance of P-- cadherin, beta-- catenin, and Wnt5 a/frizzled forprogression of melanocytic tumors and prognosis in cutaneousmelanoma显示文摘 | Bachmann IM Straume O Puntervoll HE | 2005 | Clin Cancer Res2005，11，86： | 1 |
| 8 | Importance of Pcadherin, beta-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma 显示文摘 | Bachmann I M Straume O Puntervoll H E | 2005 | Clin Cancer Res2005，11，241： | 1 |
| 9 | High power (80 W) potassium-titanyl-phosphate laser vaporization of the prostate in 66 high risk patients显示文摘 | Reich O Bachmann A Siebels M | 2005 | J Urol2005，173，1： | 1 |
| 10 | Extended methodology for determining wetting properties of porous media显示文摘 | Bachmann J Woche S K Goebel M O | 2003 | Water Resour Res2003，39，： | 1 |
| 11 | EZH2 expression is associated with high proliferation rate and aggression tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast显示文摘 | Bachmann I M Halvorsen O J Collett K | 2006 | J Clin Oneol2006，24，2： | 1 |
| 12 | Critical review of lasers in benign prostatic hyperplasia(BPH)显示文摘 | Gravas S Bachmann A Reich O | | 0，，07： | 1 |
| 13 | Water potential and aggregate size effects on contact angle and surface energy显示文摘 | Goebel M O Bachmann J Woche S K | 2004 | Soil Sci Soc Am J2004，68，： | 1 |
| 14 | Carbon mineralization in soil: Impact of wetting-drying, aggregation and water repellency显示文摘 | Lamparter A Bachmann J Goebel M O Woche S K | 2009 | Geoderma2009，150，34： | 1 |
| 15 | High power (80 W ) potassium- titanyl- phosphate laser vaporization of the pros- tate in 66 high risk patients 显示文摘 | REICH O BACHMANN A SIEBELS M | 2005 | J Urol2005，173，1： | 1 |
| 16 | Experimental comparison of high power (80 W) potassium titanyl phosphate laser vaporization and transurethral resection of the prostate 显示文摘 | REICH O BACHMANN A SCHNEEDE P el al | 2004 | J Urol2004，171，： | 1 |
| 17 | Surgical treatment in chronic pancreatitis timing and type of procedure 显示文摘 | Bachmann K Kutup A Mann O | 2010 | Best Pract Res Clin Gastroenterol2010，24，3： | 1 |
| 18 | Processing a trillion ceils per mouse click 显示文摘 | Hall A Bachmann O Btissow R | 2012 | PVLDB2012，6，11： | 1 |
| 19 | Microsatellite evolution:mutations,sequence variation,and homoplasy in the hypervariable avian microsatellite locus HrU10显示文摘 | Anmarkrud J A Kleven O Bachmann L | | 0，，： | 1 |
| 20 | Experimental comparison of high power(80W)potassium titanyl phosphate laser vaporization and transurethral resection of the prostate显示文摘 | Reich O Bachmann A Schneede P | 2004 | J Urol2004，171，61： | 1 |
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