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| 1 | Rubber band ligation for 750 cases of symptomatic hemorrhoids out of 2200 cases显示文摘AIM: To study the results for the treatment of symptomatic hemorrhoids using rubber band ligation (RBL) method. METHODS: A retrospective study for 750 patients who came to the colorectal unit from June, 1998 to September, 2006, data was retrieved from archived fi les. RBL was performed using the Mc Gown applicator on an outpatient basis. The patients were asked to return to out-patient clinic for follow up at 2 wk, 1 mo, 6 mo and through telephone call every 6 mo for 2 years). RESULTS: After RBL, 696 patients (92.8%) were cured with no difference in outcome for second or third degree hemorrhoids (P = 0.31). Symptomatic recurrence was detected in 11.04% after 2 years. A total of 52 patients (6.93%) had 77 complications from RBL which required no hospitalization. Complications were pain, rectal bleeding and vaso-vagal symptoms(4.13%, 4.13% and 1.33% of patients, respectively). At 1 mo there were a significant improvement in mean SF-36 scores over baseline in five items, while after 2 years there were improvement in all items over baseline, but not significant. No significant manometeric changes after band ligation. CONCLUSION: RBL is a simple, safe and effective method for treating symptomatic second and third degree hemorrhoids as an out patient procedure with signifi cant improvement in quality of life. RBL doesn't alter ano-rectal functions. | Ayman M El Nakeeb Amir A Fikry Waleed H Omar Elyamani M Fouda Tito A El Metwally Hosam E Ghazy Sabry A Badr Mohmed Y Abu Elkhar Salih M Elawady Hisham H Abd Elmoniam Waiel W Khafagy Mosaad M Morshed Ramadan E El Lithy Mohamed E Farid | 2008 | World Journal of Gastroenterology2008，14，42： | 24 |
| 2 | Hepatitis B genotypes: Relation to clinical outcome in patients with chronic hepatitis B in Saudi Arabia显示文摘AIM: To identify the most common hepatitis B virus (HBV) genotype in Saudi Arabia, and correlate the prevailing genotypes with the clinical outcome of patients. METHODS: Patients were consecutively recruited from the hepatology clinics of two tertiary care referral cen- ters. Patients were categorized into 4 different groups: group 1, patients with hepatitis B and normal liver en- zymes; group 2, patients with hepatitis B and abnormal liver enzymes but without cirrhosis; group 3, patients with hepatitis B and liver cirrhosis; group 4, patients with hepatitis B and hepatocellular carcinoma. All patients had a positive hepatitis B surface antigen (HBsAg). Ge- notyping of HBV was performed by nested PCR-mediated amplification of the target sequence and hybridization with sequence-specific oligonucleotides. RESULTS: Seventy patients were enrolled in this study. They were predominantly male (72.9%) in their mid- forty’s (mean age 47 years). Forty-nine (70%) patients were hepatitis B envelope antigen (HBeAg) negative. The majority of patients (64%) acquired HBV through unknown risk factors. Hepatitis B genotyping revealed that 57 patients (81.4%) were genotype D, 1 patient (1.4%) had genotype A, 1 patient (1.4%) had geno- type C, and 4 patients (5.7%) had genotype E, while 7 patients (10%) had mixed genotype (4 patients ADG, 1 patient DE, 1 patient DF, and 1 patient ADFG). Based on univariate analysis of genotype D patients, significant predictors of advanced liver disease were age, gender, aspartate transaminase, alanine transaminase, albumin,bilirubin, and alkaline phosphatase (all P < 0.001). In multivariate analysis decreased hemoglobin (r = -0.05; 95% CI: -0.08 to -0.03; P = 0.001) and albumin levels (r = -0.004; 95% CI: -0.007 to -0.001; P = 0.002) were highly significant predictors of advanced liver disease. In patients with HBV genotype D, HBeAg negativity was found to increase across advancing stages of liver dis- ease (P = 0.024). CONCLUSION: This study highlights that the vast ma- jority of Saudi patients with chronic hepatitis B have genotype D. No correlation could be observed between the different genotypes and epidemiological or clinical factors. The relationship between genotype D and HBeAg status in terms of disease severity needs to be further elucidated in larger longitudinal studies. | Ayman A Abdo Badr M Al-Jarallah Faisal M Sanai Ahmad S Hersi Khalid Al-Swat Nahla A Azzam Manal Al-Dukhayil Amira Al-Maarik Faleh Z Al-Faleh | 2006 | World Journal of Gastroenterology2006，12，43： | 7 |
| 3 | Role of relevant immune-modulators and cytokines in hepatocellular carcinoma and premalignant hepatic lesions显示文摘AIM To assess the levels of different immune modulators in patients with hepatocellular carcinoma(HCC),in relation to other hepatic diseases.METHODS Eighty-eight patients were included in the current study and represented patients with HCC(20),liver cirrhosis(28) and chronic hepatitis(CH;25),and normal controls(NC;15).Peripheral blood was isolated for immunophenotyping of active myeloid dendritic cells(m DCs;CD1 c and CD40),mature inactive myeloid cells(CD1 c and HLA),active plasmacytoid cells(p DCs;CD303 and CD40),mature inactive p DCs(CD30 and HLA),active natural killer(NK) cells(CD56 and CD161),active NK cells(CD56 and CD314) and inactive NK cells(CD56 and CD158) was done by flow cytometry.Serum levels of interleukin(IL)-2,IL-10,IL-12,IL-1β,interferon(IFN)-α,IFN-γ and tumor necrosis factor(TNF)-αR2 were assessed by ELISA.RESULTS Active m DCs(CD1 C+/CD40+) and inactive m DCs(CD1 c+/HLA+) were significantly decreased in HCC patients in relation to NC(P < 0.001).CD40+ expression on active p DCs was decreased in HCC patients(P < 0.001),and its level was not significantly changed among other groups.Inactive p DCs(CD303+/HLA+),inactive NKs(CD56+/CD158+) and active NKs(CD56+/CD161+) were not statistically changed among the four groups studied;however,the latter was increased in CH(P < 0.05).NKG2 D was statistically decreased in HCC,CH and cirrhosis(P < 0.001),and it was not expressed in 63%(12/20) of HCC patients.There was significant decrease of IL-2,IFN-α and IFN-γ(P < 0.001),and a significant increase in IL-10,IL-1β,and TNF-αR2(P <0.01,P < 0.001 and P < 0.001;respectively) in HCC patients.There was inverted correlation between IL-12 and IL-1β in HCC(r =-0.565,P < 0.01),with a strong correlation between p DCs(CD303+/CD40+) and NKs(CD56+/CD161+;r = 0.512,P < 0.05) as well as inactive m DCs(CD1 c+/HLA+) and inactive NK cells(CD56+/CD158+;r = 0.945,P < 0.001).CONCLUSION NKG2 D,CD40,IL-2 and IL-10 are important modulators in the development and progression of HCC. | Abdel-Rahman N Zekri Somaya El Deeb Abeer A Bahnassy Abeer M Badr Mona S Abdellateif Gamal Esmat Hosny Salama Marwa Mohanad Ahmed Esam El-dien Shimaa Rabah Assmaa Abd Elkader | 2018 | World Journal of Gastroenterology2018，24，11： | 6 |
| 4 | Primary peritonitis in children with nephrotic syndrome 显示文摘 | Lasry F Badre A Naim A et ol | 2005 | Nephrol Ther2005，1，5： | 1 |
| 5 | Application of tracking multi-model control to a nonlinear thermal process 显示文摘 | BADR A | 1990 | Int J Systems Science1990，21，9： | 1 |
| 6 | A comparative study on the starting methods of three phase wound- rotor induction motor-Part I显示文摘 | Hamouda R M Alolah A I Badr M A | 1999 | IEEE Trans on Energy Conversion1999，14，4： | 1 |
| 7 | Characterisitcs of flow field and water concentration in a horizontal dedleg 显示文摘 | Habib M A Badr H M Said S A M | 2005 | Heal Mass Transfer2005，41，： | 1 |
| 8 | Application of tracking multimodel control to a non-linear thermal process显示文摘 | BADR A BINDER Z REY D | | 0，，09： | 1 |
| 9 | TSRG cryptosystem显示文摘 | Dakroury Y Badr A | 2003 | Design and Implementation2003，2，2： | 1 |
| 10 | Endoscopically assisted minimally invasive microvascular decompression of hemifacial spasm 显示文摘 | Badr E1 Dine M El Garem H F Talaat A M | 2002 | Otol Neurotol2002，23，2： | 1 |
| 11 | Effect of geometry on flow fiehl and oil/water separation in vertical deadlegs 显示文摘 | Habib M A Said S A M Badr H M | 2005 | International Journal for Numerical Meth- ods in Heat & Fluid Flow2005，15，4： | 1 |
| 12 | Weighted multi-model control显示文摘 | BADR A BINDER Z REY D | | 0，，01： | 1 |
| 13 | Biomass resources for energy in north-eastern Brazil显示文摘 | Filho P A Badr O | 2004 | Applied Energy2004，77，： | 1 |
| 14 | Aqueous extract of propolis as corrosion inhibitor for carbon steel in aqueous solutions显示文摘 | Fouda A S Badr A H | 2013 | African J Pure Appl Chem2013，7，10： | 1 |
| 15 | Multi-model control of MIMO systems:location and control algorithms显示文摘 | ALY A BADR A BINDER Z | | 0，，09： | 1 |
| 16 | Recurrent urinary tract infections management in women : a review 显示文摘 | Al Badr A Al Shaikh G | 2013 | Sultan Qaboos Univ Med J2013，13，3： | 1 |
| 17 | Folliculosebaceous cystic hamartoma of the nipple:a case report显示文摘 | Badr A Lakshmiah GR | 2009 | J Cutan Pathol2009，36，5： | 1 |
| 18 | Determination of dissolved organic nitrogen in natural waters using high-temperature catalytic oxidation显示文摘 | BADR S A ACHTERBERG E P TAPPIN A D | 2003 | Trends in Analytical Chemistry2003，22，： | 1 |
| 19 | Selection, integration, and conflict monitoring; assessing the nature and generality of prefrontal cognitive control mechanisms显示文摘 | BADRE D WAGNER A D | 2004 | Neuron2004，41，3： | 1 |
| 20 | Biomass resources for energy in North-Eastern Brazil显示文摘 | Filho P A Badr O | 2004 | Applied Energy2004，77，： | 1 |
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