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| 1 | Reduction of the closure time of postoperative enterocutaneous fistulas with fibrin sealant显示文摘AIM: To assess whether the use of fibrin sealantshortens the closure time of postoperative enterocutaneous fistulas (ECFs). METHODS: The prospective case-control study included 70 patients with postoperative ECFs with an output of < 500 mL/d, a fistulous tract of > 2 cm and without any local complication. They were divided into study (n = 23) and control groups (n = 47). Esophageal, gastric and colocutaneous fistulas were monitored under endoscopic visualization, which also allowed fibrin glue application directly through the external hole. Outcome variables included closure time, time to resume oral feeding and morbidity related to nutritional support. RESULTS: There were no differences in mean age, fistula output, and follow-up. Closure-time for all patients of the study group was 12.5 ± 14.2 d and 32.5 ± 17.9 d for the control group (P < 0.001), and morbidity related to nutritional support was 8.6% and 42.5%, respectively (P < 0.01). In patients with colonic fistulas, complete closure occurred 23.5 ± 19.5 d after the first application of fibrin glue, and spontaneous closure was observed after 36.2 ± 22.8 d in the control group (P = 0.36). Recurrences were observed in 2 patients because of residual disease. One patient of each group died during follow-up as a consequence of septic complications related to parenteral nutrition. CONCLUSION: Closure time was significantly reduced with the use of fibrin sealant, and oral feeding was resumed faster. We suggest the use of fibrin sealant for the management of stable enterocutaneous fistulas. | Jorge Avalos-González Eliseo Portilla-deBuen Caridad Aurea Leal-Cortés Abel Orozco-Mosqueda María del Carmen Estrada-Aguilar Gabriela Abigail Velázquez-Ramírez Gabriela Ambriz-González Clotilde Fuentes-Orozco Aldo Emmerson Guzmán-Gurrola Alejandro González-Ojeda | 2010 | World Journal of Gastroenterology2010，16，22： | 10 |
| 2 | Exercise manual for liver disease patients显示文摘AIM: To increase inspiratory muscle strength and improve the quality of life of candidates for liver transplantation.METHODS: Twenty-three candidates for liver transplantation participated in the control group and 14 made up the intervention group. The control group consisted of 18 men and 5 women, body mass index(BMI) 27.3 ± 4.5 kg/m2 and Model for End-Stage Liver Disease(MELD) 18.2 ± 6.1. The intervention group consisted of 11 men and 3 women, BMI 28.6 ± 5.4 kg/m2 and MELD 18 ± 4.5. The presence or absence of ascites was identified in the first patient evaluation and after three months. We evaluated maximal inspiratory pressure(MIP) and maximal expiratory pressure, spirometry, root mean square(RMS) of diaphragm and rectus abdominis, and the quality of life. The exercises were performed daily by patients at home for three months and were supervised at distance monthly. The manual consisted of diaphragmatic breathing exercises, diaphragmatic isometric exercise, Threshold IMT®, lifting upper limbs with a bat and strengthening the abdomen. RESULTS: There was significant difference(P = 0.01) between the first(initial) and the third month(final) MIP in the control group and in the intervention group, but there was no difference(P = 0.45) between the groups.The RMS of the diaphragm was lower(P = 0.001) and the functional capacity was higher(P = 0.006) in the intervention group compared to the control. The general health and mental health domains received higher scores after three months in the control group(P = 0.01) and the intervention group(P = 0.004), but there was no significant difference between them. The comparison between the presence of initial ascites with the presence of ascites was performed after three months in the control group(P = 0.083) and intervention group(P = 0.31). There was no significant difference, in relation to the presence of ascites after three months between groups(P = 0.21). In the intervention group, patients with ascites at the end of the time period had decreased scores on the social aspects SF-36 domain(P = 0.023) compared to those who had no ascites. CONCLUSION: The proposed exercises provide an increase in the inspiratory muscle strength and improve functional capacity, consequently bettering the quality of life of liver disease patients. | Vivian Limongi Daniele Costa Dos Santos Aurea Maria de Oliveira da Silva Ilka de Fátima Santana Ferreira Boin Raquel Silveira Bello Stucchi | 2016 | World Journal of Transplantation2016，6，2： | 3 |
| 3 | Cost-effectiveness of enhanced liver fibrosis test to assess liver fibrosis in chronic hepatitis C virus and alcoholic liver disease patients显示文摘AIM To assess liver fibrosis(LF) in hepatitis C virus(HCV) and alcoholic liver disease(ALD), estimate health outcomes and costs of new noninvasive testing strategies METHODS A Markov model was developed to simulate LF progression in HCV and ALD for a cohort of 40-yearold men with abnormal levels of transaminases. Three different testing alternatives were studied: a single liver biopsy; annual Enhanced liver fibrosis(ELF?) followed by liver stiffness measurement(LSM) imaging as a confirmation test if the ELF test is positive; and annual ELF test without LSM. The analysis was performed from the perspective of a university hospital in Spain.Clinical data were obtained from published literature. Costs were sourced from administrative databases of the hospital. Deterministic and probabilistic sensitivity analyses were performed.RESULTS In HCV patients, annual sequential ELF test/LSM and annual ELF test alone prevented respectively 12.9 and 13.3 liver fibrosis-related deaths per 100 persons tested, compared to biopsy. The incremental costeffectiveness ratios(ICERs) were respectively €13400 and €11500 per quality-adjusted life year(QALY). In ALD, fibrosis-related deaths decreased by 11.7 and 22.1 per 100 persons tested respectively with sequential ELF test/LSM and annual ELF test alone. ICERs were €280 and €190 per QALY, respectively.CONCLUSION The use of the ELF test with or without a confirmation LSM are cost-effective options compared to a single liver biopsy for testing liver fibrosis in HCV and ALD patients in Spain. | Marcelo Soto Laura Sampietro-Colom Luis Lasalvia Aurea Mira Wladimiro Jiménez Miquel Navasa | 2017 | World Journal of Gastroenterology2017，23，17： | 2 |
| 4 | Wavelet -based detection of outliers in financial time series 显示文摘 | AUREA G HELENA V | 2010 | Computational Statistics and Data Analysis2010，54，11： | 1 |
| 5 | Gemcitabine Doublets in Advanced Pancreatic Cancer: Should We Move On? 显示文摘 | Caio Max Sao Pedro Rocha Lima and Aurea Maria Flores | 2006 | J Clin Oncol2006，24，3： | 1 |
| 6 | Formation of protein-polyphenol haze in beverages显示文摘 | Karl J Siebert Aurea Carrasco Penelope Y Lynn | 1996 | J Agric Food Chem1996，44，： | 1 |
| 7 | Wavelet-based detection of outliers in financial time series 显示文摘 | Aurea Grane Helena Veiga | 2010 | Compu- tational Statistics and Data Analysis2010，，54： | 1 |
| 8 | Simple Orbit Determination using GPS based on a least-squares algorithm employing sequential givens rotations显示文摘 | Rodolpho Vilhena de Moraes Aurea Aparecida da Silva Koiti Kuga | 2006 | Mathematical Problems in Engineering2006，，： | 1 |
| 9 | Gemcitabine Doublets in Advanced Pancreatic Cancer: Should We Move On显示文摘 | Caio Max Sao Pedro Rocha Lima Aurea Maria Florcs | 2006 | Journal of Clinical Oncology2006，24，3： | 1 |
| 10 | Developing sales force relationalism: The role of distributive and procedural justice显示文摘 | Vishal Kashyap Aurea Helena Puga Ribeiro Anthony Asare and Thomas G Brashear | 2007 | Journal of Personal Selling & Sales Management2007，27，3： | 1 |
| 11 | Mapping the domain of troponin T responsible for the activation of actomyosin ATPase activity显示文摘 | Clóvis R N Aurea D S Chuck S F Fernando C R | | J Biol Chem0，275，27： | 1 |
| 12 | Level evolution of physical activity after six months of monitoring in sedentary individuals through emails显示文摘 | Aurea CVRD Pinto CGdS Marega M | 2012 | Medicine & Science in Sports & Exercise2012，44，5： | 1 |
| 13 | Wavelet-based detection of outliers in financial time series 显示文摘 | Aurea Grane Helena Veiga | 2010 | Computational Statistics and Data Analysis2010，，54： | 1 |
| 14 | Wavelet-based detection of outliers in financial time series显示文摘 | Aurea G Veiga H | 2010 | Computational Statistics and Data Analysis2010，54，11： | 1 |
| 15 | SLAP lesions: Anatomy, clinical presentation, MR imaging diagnosis and characterization显示文摘 | Debra Chang Aurea Mohana-Borges Maya Borso Christine B. Chung | 2008 | European Journal of Radiology2008，，1： | 1 |
| 16 | Effects of Water deficit stress and recovery on the root water relations of trembling aspen (Populus tremuloides) seedlings显示文摘 | J Aurea Siemens Janusz J Zwiazek | 2003 | Plant Science2003，165，： | 1 |
| 17 | “Supplier-manufacturer relationships in the Brazilian auto industry:an exploration of distinctive elements显示文摘 | Celso Claudio de Hildebrand e Grisi Aurea Helena Puga Ribeiro | 2004 | Journal of Business & Industrial Marketing2004，19，6： | 1 |
| 18 | Affective dimension in cognitive maps of Barcelona and Sao Paulo显示文摘 | Zulmira Aurea Cruz Bomfim Enric Pol Urrutia | 2005 | International Journal of Psychology2005，，1： | 1 |
| 19 | Formation of protein-polyphenol haze in beverages显示文摘 | Karl J Siebert Aurea Carrasco Penelope Y Lynn | 1996 | J Agric Food Chem1996，44，： | 1 |
| 20 | Giant leiomyoma of the esophagus显示文摘 | Aurea P Grzzia M Petrella F | 2002 | Eur J cardiothorac surg2002，22，6： | 1 |
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