|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Replication of interleukin 23 receptor and autophagy-related 16-like 1 association in adult-and pediatric-onset inflammatory bowel disease in Italy显示文摘AIM: To investigate gene variants in a large Italian inflammatory bowel disease (IBD) cohort, and to analyze the correlation of sub-phenotypes (including age at diagnosis) and epistatic interaction with other IBD genes. METHODS: Total of 763 patients with Crohn's disease (CD, 189 diagnosed at age < 19 years), 843 with ulcerative colitis (UC, 179 diagnosed <19 years), 749 healthy controls, and 546 healthy parents (273 trios) were included in the study. The rs2241880 [autophagy-related 16-like 1 (ATG16L1)], rs11209026 and rs7517847 [interleukin 23 receptor (IL23R)], rs2066844, rs2066845, rs2066847 (CARD15), rs1050152 (OCTN1), and rs2631367 (OCTN2) gene variants were genotyped. RESULTS: The frequency of G allele of ATG16L1 SNP (Ala197Thr) was increased in patients with CD compared with controls (59% vs 54% respectively) (OR = 1.25, CI = 1.08-1.45, P = 0.003), but not in UC (55%). The frequency of A and G (minor) alleles of Arg381Gln, rs11209026 and rs7517847 variants of IL23R were reduced significantly in CD (4%, OR = 0.62, CI = 0.45-0.87, P = 0.005; 28%, OR = 0.64, CI = 0.55-0.75, P < 0.01), compared with controls (6% and 38%, respectively). The A allele (but not G) was also reduced signifi cantly in UC (4%, OR = 0.69, CI = 0.5-0.94, P = 0.019). No association was demonstrated with sub-phenotypes and interaction with CARD15 , and OCTN1/2 genes, although both gene variants were associated with pediatric-onset disease. CONCLUSION: The present study confirms the association of IL23R polymorphisms with IBD, and ATG16L1 with CD, in both adult- and pediatric-onset subsets in our study population. | Anna Latiano Orazio Palmieri Maria Rosa Valvano Renata D'Incà Salvatore Cucchiara Gabriele Riegler Anna Maria Staiano Sandro Ardizzone Salvatore Accomando Gian Luigi de Angelis Giuseppe Corritore Fabrizio Bossa Vito Annese | 2008 | World Journal of Gastroenterology2008，14，29： | 3 |
| 2 | The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: Special situations显示文摘 | Gert Van Assche Axel Dignass Walter Reinisch C. Janneke van der Woude Andreas Sturm Martine De Vos Mario Guslandi Bas Oldenburg Iris Dotan Philippe Marteau Alessandro Ardizzone Daniel C. Baumgart Geert D’Haens Paolo Gionchetti Francisco Portela Boris Vuce | 2009 | Journal of Crohn’s and Colitis2009，，1： | 3 |
| 3 | OC.06.3 ADALIMUMAB IN ACTIVE ULCERATIVE COLITIS: A “REAL-LIFE” OBSERVATIONAL STUDY显示文摘 | A. Armuzzi L. Biancone M. Daperno A. Coli V. Annese S. Ardizzone P. Balestrieri F. Bossa F. Castiglione M. Cicala S. Danese R. D’Incà P. Dulbecco G. Feliciangeli W. Fries S. Genise P. Gionchetti S. Gozzi A. Kohn R. Lorenzetti M. Milla S. Onali A. Orlando | 2012 | Digestive and Liver Disease2012，，： | 1 |
| 4 | Mn3O4 and gamma-MnOOH powders, preparation, phase composition and XPS characterisation显示文摘 | D Tirelli C L Bianchi | 1998 | Colloids and Surfaces1998，134，3： | 1 |
| 5 | Immunomodulatory effects of 1,25-dihydroxyvitamin D3on TH1/TH2 cytokines in inflammatory bowel disease:an in vitro study显示文摘 | Ardizzone S Cassinotti A Trabattoni D | 2009 | Int J Immunopathol Pharmacol2009，22，1： | 1 |
| 6 | Immunomodulatory effects of 1,25-dihydroxyvitamin D3 on TH1/TH2 cytokines in inflammatory bowel disease:an in vitro study显示文摘 | Ardizzone S Cassinotti A Trabattoni D | 2009 | Int J Immunopath Pharmacol(50394-6320)2009，22，1： | 1 |
| 7 | 显示文摘 | Ardizzone S Bianchi C L Tirelli D | 1998 | Colloids and Surfaces1998，134，： | 1 |
| 8 | Validated age and growth estimatesfor the shortfin mako, lsurus oxyrinchus, in the North Atlantic Ocean 显示文摘 | NATANSON L J KOHLER N E ARDIZZONE D | 2006 | Environmental Biology of Fishes2006，77，34： | 1 |
| 9 | The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: Special situations显示文摘 | Gert Van Assche Axel Dignass Walter Reinisch C. Janneke van der Woude Andreas Sturm Martine De Vos Mario Guslandi Bas Oldenburg Iris Dotan Philippe Marteau Alessandro Ardizzone Daniel C. Baumgart Geert D’Haens Paolo Gionchetti Francisco Portela Boris Vuce | 2009 | Journal of Crohn’s and Colitis2009，，1： | 1 |
| 10 | Immunomodula- tory effects of 1, 25-dihydroxyvitamin D3 on TH1/TH2 cytokines in inflammatory bowel disease: an in vitro study显示文摘 | Ardizzone S Cassinotti A Trabattoni D | 2009 | Int J Immu- nopathol Pharmacol2009，22，1： | 1 |
| 11 | M n3O4 and MnOOH powers, preparation, phase composition and XPS eharacterisation 显示文摘 | S Ardizzone C L Bianch D Tirelli | 1998 | Colloids and Surface1998，134，： | 1 |
| 12 | Biology, spatial distribution and population dynamics of Lepilotrigla cavillone (Pisces: Triglidae) in the Central Tyrrhenian Sea显示文摘 | Colloca F Cardinale M Ardizzone G D | 1997 | Fisheries Research1997，32，1： | 1 |
| 13 | Mn3O4 and MnOOH powers, Preparation, phase composition and XPS characterization显示文摘 | ARDIZZONE S BLANCH C L TIRELLI D | 1998 | Colloids and Surface1998，134，： | 1 |
| 14 | Yellow Pr-Zircon pigments - the role of praseodymium and of the mineralizer显示文摘 | Nero G D Cappalletti G Ardizzone S | 2004 | Journal of the European Ceramic Society2004，24，14： | 1 |
| 15 | Heme and iron metabolism:role in cerebral hemorrhage显示文摘 | Wagner K R Sharp F R Ardizzone T D | 2003 | J Cereb Blood Flow Metab2003，23，6： | 1 |
| 16 | Glutamate receptorblockade at tenuates glucose hypermetabolism in perihematomalbrain after experi mental intracerebral hemorrhage in rat 显示文摘 | Ardizzone T D Lu A G W agner K R | 2004 | Stroke2004，35，11： | 1 |
| 17 | Immunomodulatory effects of 1,25-dihydroxyvitamin D3 on TH1/TH2 cytokines in inflammatory bow el disease:an in vitro study 显示文摘 | Ardizzone S Cassinotti A Trabattoni D | 2009 | Int J Immunopathol Pharmacol2009，22，1： | 1 |
| 18 | Adalimumab in active ulcerative colitis: A “real-life” observational study显示文摘 | Alessandro Armuzzi Livia Biancone Marco Daperno Alessandra Coli Daniela Pugliese Vito Annese Annalisa Aratari Sandro Ardizzone Paola Balestrieri Fabrizio Bossa Maria Cappello Fabiana Castiglione Michele Cicala Silvio Danese Renata D’Incà Pietro Dulbecco G | 2013 | Digestive and Liver Disease2013，，： | 1 |
| 19 | Heme and iron metabolism: role in cerebral hemorrhage 显示文摘 | Wagner K R Sharp F R Ardizzone T D | 2003 | J Cereb Blood Flow Metab2003，23，： | 1 |
| 20 | Inhibition of glucose transport in PC 12 cells by the atypical antipsyehotic drugs risperidone and clozapine, and structural analogs of clozapine 显示文摘 | Ardizzone T D Bradley R J Freeman A M | 2001 | Brain Res2001，923，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员