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| 1 | Analyzing predictors of graft survival in patients undergoing liver transplantation with donors aged 70 years and over显示文摘AIM To increase the number of available grafts.METHODS This is a single-center comparative analysis performed between April 1986 and May 2016. Two hundred and twelve liver transplantation(LT) were performed with donors ≥ 70 years old(study group). Then, we selected the first cases that were performed with donors < 70 years old immediately after the ones that were performed with donors ≥ 70 years old(control group).RESULTS Graft and patient survivals were similar between both groups without increasing the risk of complications, especially primary non-function, vascular complications and biliary complications. We identified 5 risk factors as independent predictors of graft survival: recipient hepatitis C virus(HCV)-positivity [hazard ratio(HR) = 2.35; 95% confidence interval(CI): 1.55-3.56; P = 0.00]; recipient age(HR = 1.04; 95%CI: 1.02-1.06; P = 0.00); donor age X model for end-stage liver disease(D-MELD)(HR = 1.00; 95%CI: 1.00-1.00; P = 0.00); donor value of serum glutamic-pyruvic transaminase(HR = 1.00; 95%CI: 1.00-1.00; P = 0.00); and donor value of serum sodium(HR = 0.96; 95%CI: 0.94-0.99; P = 0.00). After combining D-MELD and recipient age we obtained a new scoring system that we called DR-MELD(donor age X recipient age X MELD). Graft survival significantly decreased in patients with a DR-MELD score ≥ 75000, especially in HCV patients(77% vs 63% at 5 years in HCV-negative patients, P = 0.00; and 61% vs 25% at 5 years in HCV-positive patients; P = 0.00). CONCLUSION A DR-MELD ≥ 75000 must be avoided in order to obtain the best results in LT with donors ≥ 70 years old. | Oscar Caso-Maestro Carlos Jiménez-Romero Iago Justo-Alonso Jorge Calvo-Pulido David Lora-Pablos Alberto Marcacuzco-Quinto Félix Cambra-Molero Alvaro García-Sesma Marina Pérez-Flecha Carlos Munoz- Arce Carmelo Loinaz-Segurola Alejandro Manrique-Municio | 2018 | World Journal of Gastroenterology2018，24，47： | 2 |
| 2 | Performance and impact on the seabed of an existing-and an experimental- otterboard: Comparison between model testing and full-scale sea trials显示文摘 | Antonello S Joana D Arc P F | 2009 | Fisheries Research2009，100，： | 1 |
| 3 | Microbleed Burden and Hematoma Expansion in Acute Intracerebral Hemorrhage显示文摘 | Martí-fàbregas Joan Delgado-mederos Raquel Granell Esther Morenas Rodríguez Estrella Marín Lahoz Juan Dinia Lavinia Carrera David Pérez De La Ossa Natalia Sanahuja Jordi Sobrino Tomás De Arce Ana María Alonso De Leci?ana María | 2013 | European Neurology . 2013 (3-4)2013，，3： | 1 |
| 4 | Cardiac epithelioid angiosarcoma presenting as cutaneous metastases显示文摘 | Val-Bernal J F Figols J Arce F P Sanz-Ortiz J | 2001 | J Cutan Pathol2001，28，5： | 1 |
| 5 | An SYBR Greenbased real-time RT-PCR assay for the detection of H5 hemagglutinin subtype avian influenza virus显示文摘 | Lester J Pérez H Díaz de Arce F Cilloni | | 0，，： | 1 |
| 6 | Pharmacokinetics and pharmscodynamics of asparaginases in antibody-negative pediatric patients with higher risk acute lymphoblastic leukemia (ALL):A report from CCG-1961 显示文摘 | Arce F J Seibel N Gaynon P S | 2006 | J Clin Oncol2006，24，18： | 1 |
| 7 | Modeling of High- Pressure Vapor-Liquid Equilibrium in Ionic Liquids + Gas Systems Using the PRSV Equation of State 显示文摘 | Pedro F Arce P Adrian Robles | 2010 | Fluid Phase Equilibria2010，295，1： | 1 |
| 8 | Role of capsule endoscopy in inflammatory bowel disease:Anything new?显示文摘Capsule endoscopy(CE)is a recently developed diagnostic method for diseases of the small bowel that is non-invasive,safe,and highly tolerable.Its role in patients with inflammatory bowel disease has been widely validated in suspected and established Crohn’s disease(CD)due to its ability to assess superficial lesions not detected by cross-sectional imaging and proximal lesions of the small bowel not evaluable by ileocolonoscopy.Because CE is a highly sensitive but less specific technique,differential diagnoses that can simulate CD must be considered,and its interpretation should be supported by other clinical and laboratory indicators.The use of validated scoring systems to characterize and estimate lesion severity(Lewis score,Capsule Endoscopy Crohn’s Disease Activity Index),as well as the standardization of the language used to define the lesions(Delphi Consensus),have reduced the interobserver variability in CE reading observed in clinical practice,allowing for the optimization of diagnoses and clinical management strategies.The appearance of the panenteric CE,the incorporation of artificial intelligence,magnetically-guided capsules,and tissue biopsies are elements that contribute to CE being a promising,unique diagnostic tool in digestive tract diseases. | Edith Pérez de Arce Rodrigo Quera Paulina Núñez F Raúl Araya | 2021 | Artificial Intelligence in Gastrointestinal Endoscopy2021，2，4： | 0 |
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