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| 1 | Quality of life after liver transplantation:State of the art显示文摘Quality of life(QoL) after deceased donor liver transplantation is increasingly recognized as a major outcome parameter. We reviewed recent publications in this rapidly evolving field in order to summarize recent achievements in the field and to define opportunities and perspectives for research and improvement of patient care. QoL does improve after liver transplantation according to a typical pattern. During the first year, there is a significant improvement in QoL. After one year, the improvement does stabilise and tends to decline slightly. In addition to the physical condition, different psychological parameters(such as depression, anxiety, sexual function) and sociodemographic elements(professional state, sex, marital state) seem to impact QoL. Opportunities for further research are the use of dedicated questionnaires and identification of influencing factors for QoL. | Louis Onghena Wouter Develtere Carine Poppe Anja Geerts Roberto Troisi Aude Vanlander Frederik Berrevoet Xavier Rogiers Hans Van Vlierberghe Xavier Verhelst | 2016 | World Journal of Hepatology2016，8，18： | 3 |
| 2 | Hepatopulmonary syndrome and portopulmonary hypertension: recent knowledge in pathogenesis and overview of clinical assessment显示文摘 | Sarah Raevens Anja Geerts Christophe Van Steenkiste Xavier Verhelst Hans Van Vlierberghe Isabelle Colle | 2015 | Liver Int2015，，6： | 2 |
| 3 | Evaluation of inflammatory and angiogenic factors in patients with non-alcoholic fatty liver disease显示文摘 | Stephanie Coulon Sven Francque Isabelle Colle An Verrijken Bram Blomme Femke Heindryckx Steffi De Munter Janne Prawitt Sandrine Caron Bart Staels Hans Van Vlierberghe Luc Van Gaal Anja Geerts | 2012 | Cytokine2012，，： | 1 |
| 4 | Oral vasodilator therapy in patients with moderate to severe portopulmonary hypertension as a bridge to liver transplantation显示文摘 | Sarah Raevens Michel De Pauw Koen Reyntjens Anja Geerts Xavier Verhelst Frederik Berrevoet Xavier Rogiers Roberto I. Troisi Hans Van Vlierberghe Isabelle Colle | 2013 | European Journal of Gastroenterology & Hepatology2013，，4： | 1 |
| 5 | Evaluation of inflammatory and angiogenic factors in patients with non-alcoholic fatty liver disease显示文摘 | Stephanie Coulon Sven Francque Isabelle Colle An Verrijken Bram Blomme Femke Heindryckx Steffi De Munter Janne Prawitt Sandrine Caron Bart Staels Hans Van Vlierberghe Luc Van Gaal Anja Geerts | 2012 | Cytokine2012，，2： | 1 |
| 6 | N -glycan based biomarker distinguishing non-alcoholic steatohepatitis from steatosis independently of fibrosis显示文摘 | Bram Blomme Sven Francque Eric Trépo Louis Libbrecht Dieter Vanderschaeghe An Verrijken Piet Pattyn Yves Van Nieuwenhove Dirk Van De Putte Anja Geerts Isabelle Colle Joris Delanghe Christophe Moreno Luc Van Gaal Nico Callewaert Hans Van Vlierberghe | 2011 | Digestive and Liver Disease2011，，4： | 1 |
| 7 | Histologically proven hepatic steatosis associates with lower testosterone levels in men with obesity显示文摘Men with obesity often present with low testosterone(T)and sex hormone-binding globulin(SHBG)levels.Several mechanisms for this have been proposed,but as SHBG is secreted by hepatocytes and sex steroids undergo hepatic metabolization,this study investigates whether severity and histological components of nonalcoholic fatty liver disease(NAFLD)are associated with sex steroid levels in obese men.This cross-sectional study included 80 obese men(age:46±11 years;body mass index:42.2±5.5 kg m^-2).Serum levels of total T and estradiol(E.)were measured using liquid chromatography coupled with tandem mass spectroscopy(LC/MS-MS)and SHBG and gonadotropins by immunoassay.Liver biopsies were evaluated using Steatosis.Activity,and Fibrosis scoring.Participants with steatohepatitis had similar median(1st quartile-3rd quartile)total T levels(7.6[5.0-11.0]nmol l^-1 vs 8.2[7.2-10.9]nmol l^-1;P=0.147),lower calculated free T(cFT)levels(148.9[122.9-188.8]pmol 1-1 s 199.5[157.3-237.6] pmol l^-1;P=0.006),and higher free E.T ratios(10.0[6.4-13.9]×10^-3 vs 7.1[5.7-10.7]×10^-3;P=0.026)compared to men with only nonalcoholic fatty liver.Among the histological components of NAFLD.only steatosis was independently associated with total T(r=-0.331.P=0.003)and cFT levels(r=-0.255.P=0.025).Obese men with.steatohepatitis have even lower cFT levels compared to those without,an association mainly driven by grade of steatosis.Whether this reflects a subgroup of men with a more severe obesity-related phenotype or results from direct relations between hepatic steatosis and sex steroid metabolism needs further investigation. | Frederique Van de Velde Marlies Bekaert Anne Hoorens Anja Geerts Guy T'Sjoen Tom Fiers Jean-Marc Kaufman Yves Van Nieuwenhove Bruno Lapauw | 2020 | Asian Journal of Andrology2020，22，3： | 0 |
| 8 | Rare case of ascites several years after liver transplantation显示文摘Case report A 67-year-old male patient with a history of liver transplantation presented with complaints of progressive abdominal distention.He had a history of alcoholic cirrhosis complicated by hepatocellular carcinoma for which he underwent orthotopic liver transplantation in 2011.Afterwards,he developed end-stage renal disease,requiring hemodialysis in 2017.In 2018,the diagnosis of high-risk essential thrombocythemia(ET)(presence of the JAK2(V617F)mutation and advanced age without a history of thrombosis)was made. | Liesbeth Deroo Anne Hoorens Xavier Verhelst Helena Degroote Hans Van Vlierberghe Anja Geerts | 2022 | Gastroenterology Report2022，10，1： | 0 |
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