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49篇 您的检索式:作者名="Anil Sharma"
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1Correlation of transient elastography with hepatic venous pressure gradient in patients with cirrhotic portal hypertension: A study of 326 patients from India显示文摘AIM To study the diagnostic accuracy of transient elastography(TE) for detecting clinically significant portal hypertension(CSPH) in Indian patients with cirrhotic portal hypertension.METHODS This retrospective study was conducted at the Institute of Liver, Gastroenterology, and Panceatico-Biliary Sciences, Sir Ganga Ram Hospital, New Delhi, on consecutive patients with cirrhosis greater than 15 years of age who underwent hepatic venous pressure gradient(HVPG) and TE from July 2011 to May 2016. Correlation between HVPG and TE was analyzed using the Spearman's correlation test. Receiver operating characteristic ( ROC) curves were prepared for determining the utility of TE in predicting various stages of portal hypertension. The best cut-off value of TE forthe diagnosis of CSPH was obtained using the Youden index.RESULTS The study included 326 patients [median age 52(range 16-90) years; 81% males]. The most common etiology of cirrhosis was cryptogenic(45%) followed by alcohol(34%). The median HVPG was 16.0(range 1.5 to 30.5) mm Hg. Eighty-five percent of patients had CSPH. A significant positive correlation was noted between TE and HVPG(rho 0.361, P < 0.001). The area under ROC curve for TE in predicting CSPH was 0.740(95%CI: 0.662-0.818)(P < 0.01). A cut-off value of TE of 21.6 k Pa best predicted CSPH with a positive predictive value(PPV) of 93%.CONCLUSION TE has a fair positive correlation with HVPG; thus, TE can be used as a non-invasive modality to assess the degree of portal hypertension. A cut-off TE value of 21.6 k Pa identifies CSPH with a PPV of 93%.Ashish Kumar Noor Muhammad Khan Shrihari Anil Anikhindi Praveen Sharma Naresh Bansal Vikas Singla Anil Arora 2017World Journal of Gastroenterology2017,23,4:8
2Management of hypersplenism in non-cirrhotic portal hypertension:a surgical series显示文摘BACKGROUND:Hypersplenism is commonly seen in patients with non-cirrhotic portal hypertension(NCPH).While a splenectomy alone can effectively relieve the hypersplenism,it does not address the underlying portal hypertension.The present study was undertaken to analyze the impact of shunt and non-shunt operations on the resolution of hypersplenism in patients with NCPH.The relationship of symptomatic hypersplenism,severe hypersplenism and number of peripheral cell line defects to the severity of portal hypertension and outcome was also assessed.METHODS:A retrospective analysis of NCPH patients with hypersplenism managed surgically between 1999 and 2009 at our center was done.Of 252 patients with NCPH,64(45 with extrahepatic portal vein obstruction and 19 with non-cirrhotic portal fibrosis) had hypersplenism and constituted the study group.Statistical analysis was done using GraphPad InStat.Categorical and continuous variables were compared using the chi-square test,ANOVA,and Student's t test.The MannWhitney U test and Kruskal-Wallis test were used to compare non-parametric variables.RESULTS:The mean age of patients in the study group was 21.81±6.1 years.Hypersplenism was symptomatic in 70.3% with an incidence of spontaneous bleeding at 26.5%,recurrent anemia at 34.4%,and recurrent infection at 29.7%.The mean duration of surgery was 4.16±1.9 hours,intraoperative blood loss was 457±126(50-2000) mL,and postoperative hospital stay 5.5±1.9 days.Following surgery,normalization of hypersplenism occurred in all patients.On long-term followup,none of the patients developed hepatic encephalopathy and 4 had a variceal re-bleeding(2 after a splenectomy alone,1 each after an esophago-gastric devascularization and proximal splenorenal shunt).Patients with severe hypersplenism and those with defects in all three peripheral blood cell lineages were older,had a longer duration of symptoms,and a higher incidence of variceal bleeding and postoperative morbidity.In addition,patients with triple cell line defects had elevated portal pressure(P=0.001),portal biliopathy(P=0.02),portal gastropathy(P=0.005) and intraoperative blood loss(P=0.001).CONCLUSIONS:Hypersplenism is effectively relieved by both shunt and non-shunt operations.A proximal splenorenal shunt not only relieves hypersplenism but also effectively addresses the potential complications of underlying portal hypertension and can be safely performed with good long-term outcome.Patients with hypersplenism who have defects in all three blood cell lineages have significantly elevated portal pressures and are at increased risk of complications of variceal bleeding,portal biliopathy and gastropathy.Rajesh Rajalingam Amit Javed Dharmanjay Sharma Puja Sakhuja Shivendra Singh Hirdaya H Nag Anil K Agarwal 2012Hepatobiliary & Pancreatic Diseases International2012,11,2:7
3在稍尖的巨大的肺的栓塞的机械故障和 thrombolysis : 未来的试用显示文摘 AIM: To assess role of combined modality of mechanical fragmentation and intralesional thrombolysis in patients with massive pulmonary embolism presenting subacutely. METHODS: Eight of 70 patients presenting in tertiary care centre of North India with massive pulmonary embolism within 4 years had subacute presentation (symptom onset more than 2 wk). These patients were subjected to pulmonary angiography with intention to treat basis via mechanical breakdown and intra lesional thrombolysis. Mechanical breakdown of embolus was accomplished with 5-F multipurpose catheter to reestablish flow, followed by intralesional infusion of urokinase (4400 IU/kg over 10 min followed by 4400 IU/kg per hour over 24 h). RESULTS: Eight patients, mean age 47.77±12.20 years presented with subacute pulmonary embolism (mean duration of symptoms 2.4 wk). At presentation, mean heart rate, shock index, miller score and mean pulmonary pressures were 101.5±15.2/min, 0.995±0.156, 23.87±3.76 and 37.62±6.67 mmHg which reduced to 91.5±12.2/min (P=0.0325), 0.789±0.139 (P=0.0019), 5.87±1.73 (P=0.0000004) and 27.75±8.66 mmHg (P=0.0003) post procedurally. Mean BP improved from 80.00±3.09 mmHg to 90.58±9.13 mmHg (P=0.0100) post procedurally. Minor complications in the form of local hematoma-minor hematoma in 1 (12.5%), and pseudoaneurysm (due to femoral artery puncture) in 1 (12.5 %) patient were seen. At 30 d and 6 mo follow up survival rate was 100% and all the patients were asymptomatic and in New York Heart Association class 1. CONCLUSION: Combined modality of mechanical fragmentation and intralesional thrombolysis appears to be a promising alternative to high risk surgical procedures in patients with subacute massive pulmonary embolism.Bishav Mohan Shibba Takkar Chhabra Naved Aslam Gurpreet Singh Wander Naresh Kumar Sood Sumati Verma Anil Kumar Mehra Sarit Sharma 2013World Journal of Cardiology2013,5,5:5
4All ileo-cecal ulcers are not Crohn's:Changing perspectives of symptomatic ileocecal ulcers显示文摘AIM To investigated clinical,endoscopic and histopathological parameters of the patients presenting with ileocecal ulcers on colonoscopy.METHODS Consecutive symptomatic patients undergoing colonoscopy,and diagnosed to have ulcerations in the ileocecal(I/C) region,were enrolled.Biopsy was obtained and theirclinical presentation and outcome were recorded.RESULTS Out of 1632 colonoscopies,104 patients had ulcerations in the I/C region and were included in the study.Their median age was 44.5 years and 59% were males.The predominant presentation was lower GI bleed(55,53%),pain abdomen ± diarrhea(36,35%),fever(32,31%),and diarrhea alone(9,9%).On colonoscopy,terminal ileum was entered in 96(92%) cases.The distribution of ulcers was as follows:Ileum alone 40%(38/96),cecum alone 33%(32/96),and both ileum plus cecum 27%(26/96).The ulcers were multiple in 98% and in 34% there were additional ulcers elsewhere in colon.Based on clinical presentation and investigations,the etiology of ulcers was classified into infective causes(43%) and noninfective causes(57%).Fourteen patients(13%) were diagnosed to have Crohn's disease(CD).CONCLUSION Non-specific ileocecal ulcers are most common ulcers seen in ileo-cecal region.And if all infections are clubbed together then infection is the most common(> 40%) cause of ulcerations of the I/C region.Cecal involvement and fever are important clues to infective cause.On the contrary CD account for only 13% cases as a cause of ileo-cecalulcers.So all symptomatic patients with I/C ulcers on colonoscopy are not Crohn's.Jay Toshniwal Romesh Chawlani Amit Thawrani Rajesh Sharma Anil Arora Hardik L Kotecha Mohan Goyal Vijendra Kirnake Pankaj Jain Pankaj Tyagi Naresh Bansal Munish Sachdeva Piyush Ranjan Mandhir Kumar Praveen Sharma Vikas Singla Rinkesh Bansal Vineet Shah Sunita Bhalla Ashish Kumar 2017World Journal of Gastrointestinal Endoscopy2017,9,7:5
52002~2005年期间萨斯喀彻温省儿科三级医疗中心因呼吸道合胞病毒感染住院的儿童病例分析(英文)显示文摘中文概呼吸道合胞病毒(RSV)是2岁以下儿童呼吸道感染最常见的病原体,也是引起婴儿病毒感染所致死亡的主要原因。到目前为止,尚未见加拿大萨斯喀彻温省RSV流行病学的研究报道。本研究的目的是描述2002年7月至2005年6月期间在萨斯喀彻温省的两个儿科三级医疗中心,即皇家大学医院(RUH)和萨斯卡通和里贾纳总医院(RGH),因RSV感染住院的儿童的流行病学特点及疾病严重程度,其中部分患儿有帕利珠单抗(palivizumab)预防史。 在上述2个医疗中心住院时间≥24h的儿童(年龄:从出生到16岁11个月)经实验室病毒鉴定确诊为RSV感染的儿童纳入本研究。在RUH中心,患儿鼻咽部分泌物经直接荧光抗体(DFA)检测阳性者确诊为RSV感染。如果DFA为阴性,则对该标本进行病毒培养。在RGH中心,所有患儿鼻咽部分泌物标本均进行DFA检测和病毒培养。确诊后对患儿的健康记录进行回顾性分析,内容包括患儿的人口统计信息、转诊模式、帕利珠单抗预防史、感染严重程度及转归。目前尚无统一的感染严重程度的判断标准,本研究根据住院时间、是否需要小儿重症监护及持续时间、是否机械通气等进行评估。在研究期间,萨斯喀彻温省的帕利珠单抗预防的标准与加拿大儿科学会(CPS)的建议一致。 2002年7月至2005年6月3年期间,总共有590名RSV儿童(包括324名男童)住院治疗,共602次住院记录,其中12名儿童住院1次以上。入院时患儿中位实足年龄为5.3个月,平均住院时间为4.0d(范围:〈1d至121.2个月)。82.4%的患儿出生时胎龄≥36周,7.5%为33-35周,9.5%≤32周。RSV感染住院情况呈现季节性模式,其中大部分发生在三月和六月。患儿最常见的临床表现为细支气管炎(70.2%),38.1%表现为肺炎,17.3%为上呼吸道感染,0.5%表现为哮吼(患儿可能同时有1个以上的临床表现)。478例(81.0%)为RSV轻度至中度感染,110例(18.6%)为重度感染。25.1%的患儿有继发性细菌感染。共有39例(6.7%)需要入住儿科重症监护病房(PICU),中位入住时间为5.0d。其中,22例重症患儿(56%)需要机械通气(通气时间中位数6.0d),14例重症患儿(36%)有继发性细菌感染。与入住普通病房的患儿比较,PICU患儿大多有如下情况:入院时年龄较小(P〈0.01),有潜在的肺部疾病(P〈0.01)或先天性心脏疾病(P=0.01),有两个或更多潜在的疾病(P〈0.01),与其他儿童共同居住(P=0.02)。在本研究过程中,2例儿童死亡,但均与RSV感染无关。 本研究有22例患儿在入院前接受过帕利珠单抗预防RSV感染,其中18例已完成至少2个月的剂量,17例(77%)有1个或以上的慢性疾病,14例(64%)出生时胎龄不超过32周。入院时中位实足年龄为5.6个月(范围0-27.5个月),中位住院时间为9.5d(范围2-271d)。大多数儿童(17/22)为轻度至中度RSV感染。 小结:RSV在萨斯喀彻温省保持较高的发病率,男性、实足年龄小于1岁的足月儿或晚期早产儿发病率较高。细支气管炎是最常见的临床表现。大多数患儿呈轻度至中度感染,但约7%的患儿需要重症监护。较小的实足年龄、潜在的肺部或心脏疾病或多个潜在疾病等因素均有可能导致患儿需要重症监护。此外,与其他孩子同住也有可能是导致患儿需要重症监护的一个因素。需要重症监护的患儿往往胎龄大于35周。虽然部分接受过帕利珠单抗预防的患儿也感染了RSV,但是其大部分患儿的病情为轻度至中度。这些曾接受过帕利珠单抗预防的患儿更可能有潜在疾病,并且出生时胎龄往往小于32周。在本研究中,无一例因RSV感染而引起的死亡病例。本研究尚浅,需要开展更深入的研究,以进一步确定RSV患儿,特别是PICU患儿以及曾接受过帕利珠单抗预防却仍然受到RSV感染的患儿的特征。Ayisha Kurji Ben Tan Jaya Bodani Bonnie Janzen Athena McConnell Rachana Bodani Derek Rajakumar Anil Sharma Koravangattu Sankaran 2014中国当代儿科杂志2014,16,10:3
6Sitagliptin,sitagliptin and metformin,or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats显示文摘Diabetic neuropathies are a family of nerve disorders caused by diabetes.Symptoms of the disease include nerve palsy,mononeuropathy,mononeuropathy multiplex,diabetic amyotrophy,painful polyneuropathy,autonomic neuropathy,and thoracoabdominal neuropathy.In this study,type 2 diabetes in rats was induced with nicotinamidestreptozotocin.Drug treatment was initiated on the d 15,with the combination regimen of metformin,pioglitazone and glimipiride or metformin and sitagliptin or sitagliptin,amitriptyline and sitagliptin and led to significantly improved glycemic control,increased grip strength and paw jumping response on d 21,28 and 35(P < 0.001).Significant increases in blood protein levels and decreases in urinary protein levels were observed in the animals treated with the different regimens on d 21,28 and 35(P < 0.001).Combined treatment of streptozotocin and nicotinamide caused marked degeneration of nerve cells,while administration of metformin and sitagliptin showed tissue regeneration and no body weight gain.In conclusion,treatment with sitagliptin and sitagliptin combined with metformin or amitriptyline results in no body weight gain,but causes an increase in grip strength and pain sensitivity,exhibits neural protection,and reverses the alteration of biochemical parameters in rats with streptozotocin-nicotinamide induced type 2 diabetes.Ashish Kumar Sharma Akash Sharma Rita Kumari Kunal Kishore Divya Sharma Bharthu Parthsarthi Srinivasan Ashok Sharma Santosh Kumar Singh Samir Gaur Vijay Singh Jatav Prashant Sharma Varnika Srivastava Sneha Joshi Megha Joshi Prashant Kumar Dhakad Davender Singh Kanawat Akanksha Mishra Anil Sharma Dharmendra Singh Ravinder Pal Singh Himmat Singh Chawda Rambir Singh Sachin Kumar Raikwar Muneem Kumar Kurmi Pankaj Khatri Ashutosh Agarwal Arshee Munajjam 2012The Journal of Biomedical Research2012,26,3:2
7Interleukin-28 and hepatitis C virus genotype-4:Treatment-induced clearance and liver fibrosis显示文摘AIM:To investigate the association between interleukin-28B(IL28B) genotype and response to treatment and hepatic fibrosis in patients with hepatitis C virus(HCV) genotype 4.METHODS:Two hundred and one HCV-genotype 4 patients were included.All patients were treated with Peginterferon alph2a/Ribavirin for 48 wk.End of treatment response(ETR) was defined as loss of detectable serum HCV RNA at the end of treatment.Sustained viral response(SVR) was defined as loss of detectable serum HCV RNA at the end of 24 wk follow up.Genotyping of IL28B rs12979860 was performed using the TaqMan assay.We used logistic regression to estimate the adjusted odds ratio(aOR) and 95%CI.RESULTS:The study included 201 HCV-genotype 4 patients.The majority of patients were men(89.6%),with a median age of 47 years,inter-quartile range(40-51).Approximately 62.5% of patients had ETR,and 49.6% had SVR.Individuals who achieved SVR were more likely to be younger(χ 2 = 4.91,P = 0.027),and less likely to have fibrosis(χ 2 = 15.54,P < 0.0001),or inflammation(χ 2 = 7.58,P = 0.006).The genotype distribution of rs12979860 was 36.2%,49.0% and 14.8% for genotypes CC,CT,and TT,respectively.In these participants,rs12979860 genotype distribution did not differ by gender(P = 0.466),pretreatment viral load(P = 0.600),inflammation(P = 0.435),or fibrosis(P = 0.291).The frequencies of IL28B rs12979860 genotypes were TT(14.8%),CT(49.0%),and CC(36.2%).Compared to rs12979860 genotype TT,aORs(95%CI) for ETR and SVR were:CC genotype,[17.55(5.34-57.69) and 5.92(2.09-16.76),respectively];CT genotype,[5.15(1.80-14.78) and 2.48(0.94-6.52),respectively].In the current study,the patients who did not achieve ETR or SVR had a lower prevalence of rs12979860 CC(17.4% and 23.3%,respectively) than individuals who had ETR or SVR(47.9% and 47.2%,respectively).Individuals with rs12979860 CC genotype had approximately 6 times the odds of SVR compared to individuals with TT genotype(aOR = 5.92;95%CI:2.09-16.76).Similarly,patients with CT genotype had SVR more often than patients with TT genotype(aOR = 2.48;95%CI:0.94-6.52).Carrying at least one copy of the C allele(genotypes CT and CC) had almost 8 times the probability of ETR compared to those with genotype rs12979860 TT(aOR = 7.87;95%CI:2.84-21.82),and approximately 3 times the odds of SVR compared to those with genotype rs12979860 TT(aOR = 3.46;95%CI:1.37-8.74).In addition,data were consistent with a significant gene-dose relationship(aOR = 4.05/allele;95%CI:2.27-7.22).The association between rs12979860 genotype and SVR was similar among those who achieved and those who did not achieve SVR.CONCLUSION:In HCV-genotype 4 patients,rs12979860 is a sensitive predictor of viral clearance,independent of viral load,age,gender or fibrosis,with no similar relation to severity of fibrosis.Moutaz Derbala Nasser Rizk Fatima Shebl Saad Alkaabi Nazeeh Eldweik Anil John Manik Sharma Rafie Yaqoob Muneera Almohanadi Mohammed Butt Khaled Alejji 2012World Journal of Gastroenterology2012,18,47:2
8Genome-Wide Organization and Expression Profiling of the NAC Transcription Factor Family in Potato (Solanum tuberosum L.)显示文摘Anil Kumar Singh Vishal Sharma Awadhesh Kumar Pal Vishal Acharya Paramvir Singh Ahuja 2013DNA Research2013,,4:2
9Influence of peach(Prunus persica Batsch)phenological stage on the short-term changes in oxidizable and labile pools of soil organic carbon and activities of carbon-cycle enzymes in the North-Western Himalayas显示文摘The labile organic carbon(C)and C-related enzymes are sensitive indicators capturing alterations of soil organic matter(SOM),even in a short-time scale.Although the effects of crop husbandry and land use change on these attributes have been well studied,there is no consensus about how plant phenology may impact them.This study aimed to determine the short-term effect o f six distinct phenological stages(PS-1:full bloom;PS-2:fruit set;PS-3:pit hardening;PS-4:physiological maturity;PS-5:60 d after physiological maturity;and PS-6:fall)o f peach on the changes in soil organic carbon(SOC)fractions of different oxidizability,labile C pools,and C-cycle enzyme activities in soils,for two consecutive years(2015 and 2016)in the North-Western Himalayas(NWH).Peach rhizosphere soils were sampled at the topsoil(0-15 cm)and subsoil(16-30 cm)layers,along with rhizosphere soils from adjacent perennial grasses,which served as a control.Values for most of the assessed parameters,including very labile C,labile C,microbial biomass C,permanganate oxidizable C,dissolved organic C,mineralizable C,amylase activity,and carboxymethyl-cellulase activity,were significantly(P<0.05)higher at PS-3 than at other phenological stages of peach.Conversely,a sudden decline in these soil variables was recorded at PS-5,followed by a slight buildup at PS-6,particularly in the topsoil of the peach orchard.Short-term changes in organic C fractions of different oxidizability,influenced by peach phenological stage,significantly(P<0.05)affected C management index,C pool index,and lability index.Both the C management index and lability index showed their highest values at PS-3 and their lowest values at PS-5,clearly indicating short-term accretion and depletion of SOC,in tandem with the peach phenological events.Principal component analysis suggested that a composite of soil indicators,including microbial biomass C,dissolved organic C,amylase,and invertase,could help detect short-term changes in SOC content.It is concluded that peach phenological events had a major impact on the short-term variations of the studied soil variables,which could be attributed to changes in the above-and belowground plant residues,as well as the extent of nutrients and water acquisition.Sovan DEBNATH Brij Lai ATTRI Anil KUMAR Arun KISHOR Raj NARAYAN Kanchan SINHA Arpan BHOWMIK Anil SHARMA Desh Beer SINGH 2020Pedosphere2020,30,5:2
10Phytochemical evaluation and antispermatogenic activity of Thevetia peruviana methanol extract in male albino rats显示文摘Rajnish Gupta Jai B. S. Kachhawa R. S. Gupta Anil Kumar Sharma M. C. Sharma M. P. Dobhal 2011Human Fertility2011,,1:1
11Direct shoot regeneration from leaf explants of Rosa damascena Mill.显示文摘Pratap Kumar Pati Madhu Sharma Anil Sood P. S. Ahuja 2004In Vitro Cellular & Developmental Biology - Plant2004,,2:1
12Synergistic Anti-Cancer Effects of Grape Seed Extract and Conventional Cytotoxic Agent Doxorubicin Against Human Breast Carcinoma Cells显示文摘Girish Sharma Anil K. Tyagi Rana P. Singh Daniel C.F. Chan Rajesh Agarwal 2004Breast Cancer Research and Treatment2004,,1:1
13Entropy weighting genetic k-means algorithm for subspace clustering 显示文摘Anil Kumar Tiwari Lokesh Kumar Sharma Rama Krishna G 2010International Journal of Computer Applica- tions2010,7,7:1
14Application of real-time RT-PCR in vector surveillance and assessment of replication kinetics of an emerging novel ECSA genotype of Chikungunya virus in Aedes aegypti显示文摘Ankita Agarwal Anil K. Singh Shashi Sharma Manisha Soni Ashish K. Thakur N. Gopalan M.M. Parida P.V.L. Rao Paban K. Dash 2013Journal of Virological Methods2013,,:1
15Plasma homocysteine: an independent or an interactive risk factor for coronary artery disease显示文摘Mili Gupta Priyanka Sharma Gitanjali Garg Kiranjeet Kaur Gurdeep Kaur Bedi Anil Vij 2004Clinica Chimica Acta2004,,1:1
16On-road emissions of CO,CO2 and NOx from four wheeler and emission estimates for Delhi显示文摘This study presents the emission factor of gaseous pollutants(CO, CO_2, and NO X) from on-road tailpipe measurement of 14 passenger cars of different types of fuel and vintage. The trolley equipped with stainless steel duct, vane probe velocity meter, flue gas analyzer, Nondispersive infra red(NDIR) CO_2 analyzer, temperature, and relative humidity(RH) sensors was connected to the vehicle using a towing system. Lower CO and higher NO X emissions were observed from new diesel cars(post 2010) compared to old cars(post 2005), which implied that new technological advancement in diesel fueled passenger cars to reduce CO emission is a successful venture,however, the use of turbo charger in diesel cars to achieve high temperature combustion might have resulted in increased NO X emissions. Based on the measured emission factors(g/kg), and fuel consumption(kg), the average and 95% confidence interval(CI) bound estimates of CO, CO_2,and NO X from four wheeler(4W) in Delhi for the year 2012 were 15.7(1.4–37.1), 6234(386–12,252),and 30.4(0.0–103) Gg/year, respectively. The contribution of diesel, gasoline and compressed natural gas(CNG) to total CO, CO_2 and NO X emissions were 7:84:9, 50:48:2 and 58:41:1respectively. The present work indicated that the age and the maintenance of vehicle both are important factors in emission assessment therefore, more systematic repetitive measurements covering wide range of vehicles of different age groups, engine capacity, and maintenance level is needed for refining the emission factors with CI.Jaiprakash Gazala Habib Anil Kumar Akash Sharma Minza Haider 2017Journal of Environmental Sciences2017,29,3:1
17Direct shoot regeneration from leaf explants of Rosa damascena Mill.显示文摘Pratap Kumar Pati Madhu Sharma Anil Sood P. S. Ahuja 2004In Vitro Cellular & Developmental Biology - Plant2004,,2:1
18Albumin microspheres as carriers for the antiarthritic drug celecoxib显示文摘Hetal Thakkar Rakesh Kumar Sharma Anil Kumar Mishra Krishna Chuttani Rayasa Ramchandra Murthy 2005AAPS PharmSciTech2005,,1:1
19Reducing shoulder dislocation without anaesthesia or assistant:Validation of a new reduction manoeuvre显示文摘Purpose:Shoulder dislocation comprises 60%of all major joint dislocations worldwide and a number of reduction techniques are described in the literature w让h varying degrees of success.The description of a large number of techniques speaks for itself that no method is effective all the times and one should be acquainted with more than one technique.An ideal method of reduction should be simple,easily reproducible,relatively painless that can be performed unassisted without sedation or anaesthesia w让h minimal or no further complications.We report our results of using a novel method of anterior shoulder reduction described recently in the literature that claims to fulfil most of the characteristics of an ideal method if not all.Methods:This prospective study was conducted in a tertiary care centre.All the cases of primary anterior shoulder dislocation presenting within three days of injury without any associated fracture or spine trauma with or without greater tuberosity fracture were included.The reduction was done using a novel method by orthopaedic residents in all cases.The need for a second reduction attempt or anaesthesia was considered a treatment failure.Time taken for reduction,pain felt during reduction and complications if any were noted.Results:There were 47(77.04%)males and 14(22.95%)females with a mean age of(37.04±12.63)years.The new technique was effective in locating a shoulder dislocation on the first attempt in 58 of the 61 dislocated shoulders(95.08%).The remaining three shoulders were reduced on second attempt by the same technique.Sedative,pre-medication or anaesthesia was not used in any case.The average time taken for the shoulder reductio n was(130.5±25.8)sec onds and con fide nee interval(95%)124-137 s.Iatrogenic complications were not seen in any of the patients.Conclusion:This relatively painless technique of shoulder reduction is easy to acquire and practice in emergency department.The advantages of this manoeuvre and its associated safety may justly lead surgeons to select it as their primary method for reduction of anterior shoulder dislocations.Rashid Anjum Subodh Pathak Atul Rai Sharma Jatin Aggarwal Aryan Sharma Vineet Pruthi Anil Kumar Chaudhary 2019Chinese Journal of Traumatology2019,22,5:1
20Degradation of methyl parathion by a mixed bacterial eulture and abacillus sp isolation from different soils显示文摘Li Tseou Anil Sharma 1989Agric Food Chem1989,37,:1
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