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| 1 | How location and cellular signaling combine to activate the NLRP3 inflammasome显示文摘NOD-,LRR-,and pyrin domain-containing 3(NLRP3)is a cytosolic innate immune sensor of cellular stress signals,triggered by infection and sterile inflammation.Upon detection of an activating stimulus,NLRP3 transitions from an inactive homo-oligomeric multimer into an active multimeric inflammasome,which promotes the helical oligomeric assembly of the adaptor molecule ASC.ASC oligomers provide a platform for caspase-1 activation,leading to the proteolytic cleavage and activation of proinflammatory cytokines in the IL-1 family and gasdermin D,which can induce a lytic form of cell death.Recent studies investigating both the cellular requirement for NLRP3 activation and the structure of NLRP3 have revealed the complex regulation of NLRP3 and the multiple steps involved in its activation.This review presents a perspective on the biochemical and cellular processes controlling the assembly of the NLRP3 inflammasome with particular emphasis on structural regulation and the role of organelles.We also highlight the latest research on metabolic control of this inflammatory pathway and discuss promising clinical targets for intervention. | Anil Akbal Alesja Dernst Marta Lovotti Matthew S.J.Mangan Róisín M.McManus Eicke Latz | 2022 | Cellular & Molecular Immunology2022，19，11： | 2 |
| 2 | Thermal and Mechanical Properties of Environment-friendly 'green' Plastics from Stearic Acid Modified-soy Protein Isolate 显示文摘 | Preeti L Anil N | 2005 | Industrial Crops and Products2005，21，： | 1 |
| 3 | Sorption and solubility of denture liners after accelerated aging显示文摘 | Hekimoglu C Anil N | 1999 | Am J Dent1999，12，1： | 1 |
| 4 | Resetting semiactives tiffness damper for seismic response control 显示文摘 | Jann N Y Kim J H Anil K A | 2000 | ASCE Journal of Structural Engineering2000，126，14： | 1 |
| 5 | Bismuth ( Ⅱ )Chloride-Zinc Promoted Selective Reduction of Aromatic Nitro Compounds to Azoxy Compounds显示文摘 | HARSHA N B DIPAK P JAGIR S S ANIL C G | 1994 | Tetrahedron Letters1994，35，19： | 1 |
| 6 | Development and characterization of a novel immobilized microbial membrane for rapid determination of biochemical oxygen demand load in industrial wastewaters显示文摘 | Rastogi Shikha Kumar Anil Mehra N K | 2003 | Biosensors and Bioelectronics2003，18，1： | 1 |
| 7 | On the origin of itinerant electron behaviour and longrange ferromagnetic order in La1-xSrxCoO3显示文摘 | GANGULY P ANIL KUMAR P S SANTHOSH P N | 1994 | J Phys Condens Matter1994，6，： | 1 |
| 8 | Development and standardization of a piezo electric immunobiosensor for foot and mouth disease virus typing 显示文摘 | Gajendragad M R Kamath K N Anil P Y | 2001 | Vet Microbiol2001，2678，4： | 1 |
| 9 | Responses in the voluntary intake of hay or silage by lactating cows to intra- ruminal infusions of sodium acetate or sodium propionate, the tonicity of rumen fluid or rumen distension显示文摘 | Anil M H Mbanya J N Symonds H W | 1993 | British Journal of Nutrition1993，69，： | 1 |
| 10 | Current techniques and results of liver resection for colorectal liver metastases显示文摘 | Hamady ZZR Anil K Hideki N | 2004 | Br Med Bull2004，70，1： | 1 |
| 11 | An investigation of mismatch losses in solar photovoltaic cell networks显示文摘 | Kaushika N D Anil K Rai | 2007 | Energy2007，，32： | 1 |
| 12 | Thermal and mechanical properties of environment friendly ' green' plastics from steric acid modified-soy protein isolate显示文摘 | PREETI L ANIL N N | 2005 | Industrial Crops and Products2005，21，1： | 1 |
| 13 | Data clustering: a review显示文摘 | Anil K Jain M N Murty P J Flynn | 1999 | ACM Computing Surveys1999，31，3： | 1 |
| 14 | Influence of primary and secondary closure of surgical wound after impacted mandibular third molar removal on postoperative pain and swelling-a comparative and split mouth study显示文摘 | Anil KD Murali KT Vinod N | | 0，，02： | 1 |
| 15 | Microleakage study of various soft denture liners by autoradiography:effect of accelerated aging显示文摘 | Hekimoglu C Buyukbas N | 2000 | J Prosthet Dent2000，84，4： | 1 |
| 16 | (2000) Coastal landform mapping between Tuticorin and Vaippar using IRS-IC data 显示文摘 | Chandrasekar N Anil Cherian Rajamanickam M | 2000 | Indian Journal of Geo- morphology2000，5，12： | 1 |
| 17 | Metal Complexes of Pyrimidine Derived Ligands : Syntheses, Characterization and X-Ray Crystal Structures of Ni(Ⅱ), Co( Ⅲ ) and Fe( Ⅲ ) Complexes of Schiff Base Ligands Derived from S-Methy/ S-Benzyl Dithiocarbazate and 2-S-Methymercapto-6-methylpyrimidine-4-carbaldehyde 显示文摘 | Somnath R Tarak N M Anil K B | 2007 | Polyhedron2007，26，12： | 1 |
| 18 | Self-reported medication adherence and cardiovascular events in patients with stable coronary heart disease显示文摘 | ANIL K SEHI S A BEEYA N | 2007 | Arch Intern Med2007，167，16： | 1 |
| 19 | A microleakage study of ceramic laminate veneers by autoradiography:effect of incisal edge preparation显示文摘 | Hekimoglu C Anil N Yalcin E | 2004 | J Oral Rehabil2004，31，3： | 1 |
| 20 | Development and standardization of a piezo electric immunobiosensor for foot and mouth disease virus typing显示文摘 | Gajendragad M R Kamath K N Anil P Y | 2001 | Vet Micro biol2001，78，4： | 1 |
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