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| 1 | Understanding the effects of radiative preheat and self-emission from shock heating on equation of state measurement at 100s of Mbar using spherically converging shock waves in a NIF hohlraum显示文摘Over the last six years many experiments have been done at the National Ignition Facility to measure the Hugoniot of materials,such asCHplastic at extreme pressures,up to 800 Mbar.The“Gbar”design employs a strong spherically converging shock launched through a solid ball of material using a hohlraum radiation drive.The shock front conditions are characterized using x-ray radiography.In this paper we examine the role of radiation in heating the unshocked material in front of the shock to understand the impact it has on equation of state measurements and how it drives the measured data off the theoretical Hugoniot curve.In particular,the two main sources of radiation heating are the preheating of the unshocked material by the high-energy kilo-electron-volt x-rays in the hohlraum and the heating of the material in front of the shock,as the shocked material becomes hot enough to radiate significantly.Using our model,we estimate that preheating can reach 4 eV in unshocked material,and that radiation heating can begin to drive data off the Hugoniot significantly,as pressures reach above 400 Mb. | Joseph Nilsen Andrea L.Kritcher Madison EMartin Robert E.Tipton Heather D.Whitley Damian C.Swift Tilo Doppner Benjamin L.Bachmann Amy E.Lazicki Natalie B.Kostinski Brian R.Maddox Gilbert W.Collins Siegfried H.Glenzer Roger W.Falcone | 2020 | Matter and Radiation at Extremes2020，5，1： | 5 |
| 2 | Burden of onchocerciasis-associated epilepsy:first estimates and research priorities显示文摘Background:Since the 1990s,evidence has accumulated of an increased prevalence of epilepsy in onchocerciasisendemic areas in Africa as compared to onchocerciasis-free areas.Although the causal relationship between onchocerciasis and epilepsy has yet to be proven,there is likely an association.Here we discuss the need for disease burden estimates of onchocerciasis-associated epilepsy(OAE),provide them,detail how such estimates should be refined,and discuss the socioeconomic impact of OAE,including a cost-estimate for anti-epileptic drugs.Main body:Providing OAE burden estimates may aid prevention of epilepsy in onchocerciasis-endemic areas by inciting and informing collaboration between onchocerciasis control programmes and mental health services.Epilepsy not only massively impacts the health of those affected,but it also carries a high socioeconomic burden for the households and communities involved.We used previously published geospatial estimates of onchocerciasis in Africa and a separately published logistic regression model quantifying the association between onchocerciasis and epilepsy to estimate the number of OAE cases.We then applied disability weights for epilepsy to quantify the burden in terms of years of life lived with disability(YLD)and estimate the cost of treatment.We estimate that in 2015 roughly 117000 people were affected by OAE across onchocerciasis-endemic areas previously under the African Programme for Onchocerciases control(APOC)mandate where OAE has ever been reported or suspected,and another 264000 persons in onchocerciasis-endemic areas where OAE has never been investigated before.The total number of YLDs due to OAE was 39300 and 88700 in these areas respectively,based on a weighted mean disability weight of 0.336.The burden of OAE is approximately 13%of the total YLDs attributable to onchocerciasis and 10%of total YLDs attributable to epilepsy.We estimated that by 2015 the total costs of treatment with antiepileptic drug for OAE cases would have been a minimum of 12.4 million US$.Conclusions:These estimates suggest a considerable health,social and economic burden of OAE in Africa.The treatment and care for people with epilepsy,especially in hyperendemic onchocerciasis areas with high epilepsy prevalence thus requires more financial and human resources. | Natalie V.S.Vinkeles Melchers Sarah Mollenkopf Robert Colebunders Michael Edlinger Luc E.Coffeng Julia Irani Tresor Zola Joseph N.Siewe Sake Jde Vlas Andrea S.Winkler Wilma A.Stolk | 2018 | Infectious Diseases of Poverty2018，7，1： | 3 |
| 3 | Curcumin-loaded polymeric nanoparticles for neuro-protection in neonatal rats with hypoxic-ischemic encephalopathy显示文摘 | Andrea Joseph Thomas Wood Chih-Chung Chen Kylie Corry Jessica M. Snyder Sandra E. Juul Pratik Parikh Elizabeth Nance | 2018 | Nano Research2018，11，10： | 2 |
| 4 | Recommendations for the Management of Hepatitis C Virus Infection Among People Who Inject Drugs显示文摘 | Geert Robaeys Jason Grebely Stefan Mauss Philip Bruggmann Joseph Moussalli Andrea De Gottardi Tracy Swan Amber Arain Achim Kautz Heino St?ver Heiner Wedemeyer Martin Schaefer Lynn Taylor Markus Backmund Olav Dalgard Maria Prins Gregory J. Dore | 2013 | Clinical Infectious Diseases . 2013 (supp)2013，，： | 1 |
| 5 | Precalence,age,distribution,and gender of patients with atrial fibrillation显示文摘 | William WF Joseph LB Andreas L | 1995 | Arch Intern Med1995，155，： | 1 |
| 6 | Recommendations for the Management of Hepatitis C Virus Infection Among People Who Inject Drugs显示文摘 | Geert Robaeys Jason Grebely Stefan Mauss Philip Bruggmann Joseph Moussalli Andrea De Gottardi Tracy Swan Amber Arain Achim Kautz Heino St?ver Heiner Wedemeyer Martin Schaefer Lynn Taylor Markus Backmund Olav Dalgard Maria Prins Gregory J. Dore | 2013 | Clinical Infectious Diseases (suppl )2013，，2： | 1 |
| 7 | A Multiple-Day Regimen of Parecoxib Sodium 20 mg Twice Daily Provides Pain Relief After Total Hip Arthroplasty显示文摘 | Eugene R. Viscusi Joseph S. Gimbel Andreas M. Halder Michael Snabes Mark T. Brown Kenneth M. Verburg | 2008 | Anesthesia & Analgesia2008，，2： | 1 |
| 8 | The Cox maze procedure in mitral valve disease: Predictors of recurrent atrial fibrillation显示文摘 | A. Marc Gillinov Jon Sirak Eugene H. Blackstone Patrick M. McCarthy Jeevanantham Rajeswaran Gosta Pettersson F. Joseph Sabik Lars G. Svensson Jose L. Navia Delos M. Cosgrove Nassir Marrouche Andrea Natale | 2005 | The Journal of Thoracic and Cardiovascular Surgery2005，，6： | 1 |
| 9 | Pure mucinous carcinoma of the breast显示文摘 | Ian K Komenaka Mahmoud B El-Tamer Andrea Troxel Diane Hamele-Bena Kathie-Ann Joseph Elizabeth Horowitz Beth-Ann Ditkoff Freya R Schnabel | 2004 | The American Journal of Surgery2004，，4： | 1 |
| 10 | Lipopolysaccharide differentially decreases plasma acyl and desacyl ghrelin levels in rats: Potential role of the circulating ghrelin-acylating enzyme GOAT显示文摘 | Andreas Stengel Miriam Goebel Lixin Wang Joseph R. Reeve Yvette Taché Nils W.G. Lambrecht | 2010 | Peptides2010，，9： | 1 |
| 11 | Use of the anterolateral thigh flap as an alternative to the rectus flap in obese and overweight pa- tients 显示文摘 | Kristin DBA Andrea P Joseph JD | 2006 | Ann Plast Surg2006，6，： | 1 |
| 12 | Prevalence, age, distribution, and gender of patients with atrial fibrillation显示文摘 | William MF Joseph LB Andreas L | 1995 | Arch Intern Med1995，155，： | 1 |
| 13 | Direct and indirect effects of self - image congruence on brand loyalty 显示文摘 | Kressmann Frank Sirgy M Joseph Herrmann Andreas Huber Frank Huber Stephanie and Lee Dong -Jin | 2006 | Journal of Business Research2006，59，9： | 1 |
| 14 | Microphysical and Thermodynamic Structure and Evolution of the Trailing Stratiform Regions of Mesoscale Convective Systems during BAMEX. Part I: Observations显示文摘 | Smith Andrea M McFarquhar Greg M Rauber Robert M Grim Joseph A Timlin Michael S Jewett Brian F Jorgensen David P | 2009 | Monthly Weather Review2009，，4： | 1 |
| 15 | A Better Landmark for Positioning a Central Venous Catheter显示文摘 | Lawrence J. Caruso Nikolaus Gravenstein A. Joseph Layon Keith Peters Andrea Gabrielli | 2002 | Journal of Clinical Monitoring and Computing2002，，6： | 1 |
| 16 | Precalence, age, distribution, and gender of patients with atrial fibrillation显示文摘 | William MF Joseph LB Andreas L | 1995 | Arch Intern Med1995，155，： | 1 |
| 17 | Evaluation of the Efficacy and Safety of Tranexamic Acid for Reducing Blood Loss in Bilateral Total Knee Arthroplasty显示文摘 | Joseph A. Karam Michael R. Bloomfield Timothy M. DiIorio Andrea M. Irizarry Peter F. Sharkey | 2014 | The Journal of Arthroplasty2014，，3： | 1 |
| 18 | Echocardiography and Cardiac Magnetic Resonance‐Based Feature Tracking in the Assessment of Myocardial Mechanics in Tetralogy of Fallot: An Intermodality Comparison显示文摘 | Asif Padiyath Paul Gribben Joseph R. Abraham Ling Li Sheela Rangamani Andreas Schuster David A. Danford Gianni Pedrizzetti Shelby Kutty | 2012 | Echocardiography2012，，： | 1 |
| 19 | Accuracy of MRI,MR Arthrography,and Ultrasound in the Diagnosis of Rotator Cuff Tears:A Meta-Analysis显示文摘 | Joseph O Laurence P Andrea J | | 0，，： | 1 |
| 20 | Hepatic decompensation/serious adverse events in post-liver transplantation recipients on sofosbuvir for recurrent hepatitis C virus显示文摘AIM: To determine the safety profile of new hepatitis C virus(HCV) treatments in liver transplant(LT) recipients with recurrent HCV infection.METHODS: Forty-two patients were identified with recurrent HCV infection that underwent LT at least 12 mo prior to initiating treatment with a Sofosbuvir-based regimen during December 2013-June 2014. Cases were patients who experienced hepatic decompensation and/or serious adverse events(SAE) during or within one month of completing treatment. Controls had no evidence of hepatic decompensation and/or SAE. HIVinfected patients were excluded. Cumulative incidence of decompensation/SAE was calculated using the Kaplan Meier method. Exact logistic regression analysis was used to identify factors associated with the composite outcome. RESULTS: Median age of the 42 patients was 60 years [Interquartile Range(IQR): 56-65 years], 33%(14/42) were female, 21%(9/42) were Hispanic, and 9%(4/42) were Black. The median time from transplant to treatment initiation was 5.4 years(IQR: 2.1-8.8 years). Thirteen patients experienced one or more episodes of hepatic decompensation and/or SAE. Anemia requiring transfusion, the most common event, occurred in 62%(8/13) patients, while 54%(7/13) decompensated. The cumulative incidence of hepatic decompensation/SAE was 31%(95%CI: 16%-41%). Risk factors for decompensation/SAE included lower pre-treatment hemoglobin(OR = 0.61 per g/d L, 95%CI: 0.40-0.88, P < 0.01), estimated glomerular filtration rate(OR = 0.95 per m L/min per 1.73 m^2, 95%CI: 0.90-0.99, P = 0.01), and higher baseline serum total bilirubin(OR = 2.43 per mg/d L, 95%CI: 1.17-8.65, P < 0.01). The sustained virological response rate for the cohort of 42 patients was 45%, while it was 31% for cases.CONCLUSION: Sofosbuvir/ribavirin will continue to be used in the post-transplant population, including those with HCV genotypes 2 and 3. Management of anemia remains an important clinical challenge. | Neal Patel Kian Bichoupan Lawrence Ku Rachana Yalamanchili Alyson Harty Donald Gardenier Michel Ng David Motamed Viktoriya Khaitova Nancy Bach Charissa Chang Priya Grewal Meena Bansal Ritu Agarwal Lawrence Liu Gene Im Jennifer Leong Leona Kim-Schluger Joseph Odin Jawad Ahmad Scott Friedman Douglas Dieterich Thomas Schiano Ponni Perumalswami Andrea Branch | 2016 | World Journal of Gastroenterology2016，22，9： | 1 |
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