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| 1 | Oxygen transfer prediction in aeration tanks using CFD显示文摘 | Yannick Fayolle Arnaud Cockx Sylvie Gillot Michel Roustan Alain Héduit | 2007 | Chemical Engineering Science2007，，24： | 3 |
| 2 | Indirect printing of hierarchical patient-specific scaffolds for meniscus tissue engineering显示文摘The complex meniscus tissue plays a critical role in the knee. The high susceptibility to injury has led to an intense pursuit for better tissue engineering regenerative strategies, where scaffolds play a major role. In this study, indirect printed hierarchical multilayered sca ffolds composed by a silk fibroin (SF) upper layer and an 80/20 (w/w) ratio of SF/ionic-doped β-tricalcium phosphate (TCP) bottom layer were developed. Furthermore, a comparative analysis between two types of sca ffolds pro- duced using di fferent SF concentrations, i.e., 8% (w/v) (Hi8) and 16% (w/v) (Hi16) was performed. In terms of architecture and morphology, the produced sca ffolds presented homogeneous porosity in both layers and no di fferences were observed when comparing both sca ffolds. A decrease in terms of mechanical performance of the sca ffolds was observed when SF concentration decreased from 16 to 8% (w/v). Hi16 revealed a static compressive modulus of 0.66 ± 0.05 MPa and dynamical mechanical properties ranging from 2.17 ± 0.25 to 3.19 ± 0.38 MPa. By its turn, Hi8 presented a compressive modulus of 0.27 ± 0.08 MPa and dynamical mechanical properties ranging from 1.03 ± 0.08 MPa to 1.56 ± 0.13 MPa. In vitro bioactivity studies showed formation of apatite crystals onto the surface of Hi8 and Hi16 bottom layers. Human meniscus cells (hMCs) and human primary osteoblasts were cultured separately onto the top layer (SF8 and SF16) and bottom layer (SF8/TCP and SF16/TCP) of the hierarchical sca ffolds Hi8 and Hi16, respectively. Both cell types showed good adhesion and proliferation as denoted by the live/dead staining, Alamar Blue assay and DNA quanti fication analysis. Subcutaneous implantation in mice revealed weak in flammation and sca ffold’s integrity. The hierarchical indirect printed SF sca ffolds can be promising candidate for meniscus TE sca ffolding applications due their suitable mechanical properties, good biological performance and possibility of being applied in a patient-speci fic approach. | Joao BCosta Joana Silva-Correia Sandra Pina Alain da Silva Morais Sílvia Vieira Hélder Pereira Joao Espregueira-Mendes Rui LReis Joaquim M.Oliveira | 2019 | Bio-Design and Manufacturing2019，2，4： | 2 |
| 3 | Codon usage and gene function are related in sequences of Arabidopsis thaliana 显示文摘 | Helene C Fred6rique L Michel C Alain H | 1998 | Gene1998，209，： | 1 |
| 4 | Thedeoxyxylulose phosphate pathway of terpenoid biosynthesisin plants and microorganisms显示文摘 | Wolfgang Eisenreicha Matthias Schwarzb Alain Cartayradeb Duilio Arigonib Meinhart H Zenkc Adelbert Bacher | 1998 | Chemistry&Biology1998，5，9： | 1 |
| 5 | Variability estimation of urban wastewater biodegradable fractions by respirometry显示文摘 | Fabienne Lagarde Marie-Hélène Tusseau-Vuillemin Paul Lessard Alain Héduit Fran?ois Dutrop Jean-Marie Mouchel | 2005 | Water Research2005，，19： | 1 |
| 6 | Rehabilitation for high frequency sensorineural hearing impairment in adults with the symphonix vibrant soundbridge: a comparative study显示文摘 | Alain U Michel M Paul H | 2003 | O tology & Neurotology2003，24，： | 1 |
| 7 | Sensory investigation of yogurt flavor perception:mutual Influence of volatiles and acidity显示文摘 | Andreas O Alain H Marcel B | 2000 | Journal Agricahure Food Chemistry2000，48，2： | 1 |
| 8 | The first encapsulation of hydroxynitrile lyase from Hevca brasiliensis in a sol-gel matrix显示文摘 | Lars V Ulf H Alain P | 2004 | Tetrahedron2004，60，10： | 1 |
| 9 | Codon usage and gene function are related in sequences of Arabidopsis thaliana 显示文摘 | Helene C Fr6d6rique L M ichel C Alain H | 1998 | Gene1998，209，12： | 1 |
| 10 | Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors显示文摘 | Salmon Hélène Franciszkiewicz Katarzyna Damotte Diane Dieu-Nosjean Marie-Caroline Validire Pierre Trautmann Alain Mami-Chouaib Fathia Donnadieu Emmanuel | 2012 | EN2012，，3： | 1 |
| 11 | Antifouling Activities and Inhibition of Mytilis Phenoxidase Marine Biotechnology 显示文摘 | Frederic Z Claire H Alain V | 2002 | Marine Biotechnology2002，4，04： | 1 |
| 12 | Risk analysis and long-term survival in patients undergoing resection of T4 lung cancer显示文摘 | Alain B Olivier B Olivier H | 2001 | Eur J Cardio Thorac Surg2001，20，： | 1 |
| 13 | Influence of Microarrays Experiments Missing Values on the Stability of Gene Groups by Hierarchical Clustering显示文摘 | Alexandre G B Serge H Alain M | 2004 | BMC Bioinformatics2004，5，： | 1 |
| 14 | Identification and Functional Analysis of the Gene Cluster for 1-Arabinose Utilization in Corynebacterium glutamicum显示文摘 | Kawaguchi H Sasaki M Alain A | 2008 | Applied and Environmental Microbiology2008，75，11： | 1 |
| 15 | Optimal component mode synthesis for medium frequency problem显示文摘 | MATHIEU H DANIEL N ALAIN C | | 0，，： | 1 |
| 16 | Noninvasive study of coronary microcirculation response to a cold pressor test显示文摘 | Isabelle Pham Minh‐Tuan Nguyen Paul Valensi Hélène Rousseau Alain Nitenberg Eric Vicaut Emmanuel Cosson | 2015 | Eur J Clin Invest2015，，： | 1 |
| 17 | High pressure thawing of fish and shellfish显示文摘 | JOCELYN R ALAIN L RAMASWAMYB H S | 2002 | Journal of Food Engineering2002，53，1： | 1 |
| 18 | Thermal fatigue of cast irons for automotive application 显示文摘 | Dhouha M Nader H Alain K | 2011 | Materials and Design2011，3，32： | 1 |
| 19 | RNA Predict: An evolutionary algorithm for RNA secondary structure prediction 显示文摘 | Kay C W Alain A D Andrew G H | 2008 | Transactions on Computational Biology and Bioinformatics2008，5，1： | 1 |
| 20 | Fuzzy Random Fields and Unsupervised Image Segmentation 显示文摘 | Helene C Alain H Wojciech P | 1993 | IEEE Trans Geosci Remot Sensing1993，31，4： | 1 |
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