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| 1 | Crystal structure of the bacterial cell-division protein FtsZ显示文摘 | L we J Amos LA | 1998 | Nature1998，391，6663： | 1 |
| 2 | Prokaryotic origin of the actin cytoskeleton显示文摘 | Van den Ent F Amos LA Lowe J | 2001 | Nature2001，413，6851： | 1 |
| 3 | Waardcnburg syndrome(WS) type I is caused by defects at multiple loci,one of which is near AL PP on chromosome:fist report of the WS consorlium 显示文摘 | Farrcr LA Grundfast KM Amos L | 1992 | Am J Hum Genet1992，50，： | 1 |
| 4 | Waardenburg syndrome (WS) type 1 is caused by defects at multiple loci, one of which is near ALPP on chromosome 2: First report of the WS Consor- tium显示文摘 | Farrer LA Gnmdfast KM Amos J | 1992 | J Genet Hum1992，50，5： | 1 |
| 5 | Gender differences in progression to AIDS and death from HIV seroconversion in a cohort of injecting drug users from 1986 to 2001显示文摘 | Garcia de la Hera M Ferreros I del Amo J | 2004 | J Epidemiol Community Health2004，58，11： | 1 |
| 6 | Waardenburg Syndrome (WS) Type Ⅰ is Caused by Defects at Multiple Foci, One of Which is Near ALPP On Chromosome 2 : First Report of the WS Consortium显示文摘 | Farrer LA Grundfast KM Amos J et ai | 1992 | Am J Hum Genet1992，50，5： | 1 |
| 7 | Waardenburg syndrome (WS) type I is caused by defects at multiple loci, one of which is near AL PP on chromosome: first report of the WS consortium 显示文摘 | Farrer LA Grundfast KM Amos J | 1992 | Am J Hum Genet1992，50，： | 1 |
| 8 | Crystal structure of the bacterial cell-division protein FtsZ显示文摘 | Lowe J Amos LA | 1998 | Nature1998，391，6663： | 1 |
| 9 | Waardenburg syndrome(WS)typeⅠis caused by defects at multiple loci,one of which is near ALPP on chromosome 2:first report of the WS consortium显示文摘 | Farrer LA Grundfast KM Amos J | 1992 | Am J Hum Genet1992，50，： | 1 |
| 10 | Investigating the genetic basis for ankylosing spondylitis:Linkage strdies with the major histocompatibility complex region 显示文摘 | Rubin LA Amos CI Wade JA | 1994 | Arthritis Rheum1994，3，： | 1 |
| 11 | Prokaryotic origin of the actin cytoskeleton显示文摘 | van den Ent F Amos LA Lowe J | 2001 | Nature2001，413，6851： | 1 |
| 12 | Waardenburg syndrome (WS) type Ⅰ is caused by defects at multiple loci,one of which is near AL PP on chromosome:first report of the WS consortium显示文摘 | Farrer LA Grundfast KM Amos J | 1992 | Am J Hum Genet1992，50，： | 1 |
| 13 | Gender differences in progression to AIDS and death from HIV serocon version in a cohort of injecting drug users from 1986 to 2001 显示文摘 | Garcia De La Hera M Ferreros I Del Amo J | 2004 | Journal of epldemiology and community health2004，58，11： | 1 |
| 14 | Waardenburg syn- drome (WS') type I is caused by defects atmultiple loci,one of which is near ALPP on chromosome 2: first report of the WS consortium显示文摘 | Farrer LA Grundfast KM Amos J | 1992 | Am J Hum Genet1992，50，： | 1 |
| 15 | Prokaryotic origin of the actin cytoskeleton显示文摘 | VAN DEN ENT F AMOS LA LOWE J | 2001 | Nature2001，413，： | 1 |
| 16 | Three dimensional reconstructions of spherical viruses by Fourier synthesis from electron micrographs 显示文摘 | Crowther RA Amos LA Finch JT | 1970 | Nature1970，226，244： | 1 |
| 17 | How taxol stabilises microtubule structure 显示文摘 | Amos LA Lowe J | 1999 | Chem Biol1999，6，3： | 1 |
| 18 | Fibrin sealant for esophageal anastomosis:A phase II study显示文摘BACKGROUND Esophagectomy is a pivotal curative modality for localized esophageal or esophagogastric junction cancer(EC or EJC).Postoperative anastomotic leakage(AL)remains problematic.The use of fibrin sealant(FS)may improve the strength of esophageal anastomosis and reduce the incidence of AL.AIM To assess the efficacy and safety of applying FS to prevent AL in patients with EC or EJC.METHODS In this single-arm,phase II trial(Clinicaltrial.gov identifier:NCT03529266),we recruited patients aged 18-80 years with resectable EC or EJC clinically staged as T1-4aN0-3M0.An open or minimally invasive McKeown esophagectomy was performed with a circular stapled anastomosis.After performing the anastomosis,2.5 mL of porcine FS was applied circumferentially.The primary endpoint was the proportion of patients with AL within 3 mo.RESULTS From June 4,2018,to December 29,2018,57 patients were enrolled.At the data cutoff date(June 30,2019),three(5.3%)of the 57 patients had developed AL,including two(3.5%)with esophagogastric AL and one(1.8%)with gastric fistula.The incidence of anastomotic stricture and other major postoperative complications was 1.8%and 17.5%,respectively.The median time needed to resume oral feeding after operation was 8 d(Interquartile range:7.0-9.0 d).No adverse events related to FS were recorded.No deaths occurred within 90 d after surgery.CONCLUSION Perioperative sealing with porcine FS appears safe and may prevent AL after esophagectomy in patients with resectable EC or EJC.Further phase III studies are warranted. | Yao-Bin Lin Jian-Hua Fu Yan Huang Yi-Huai Hu Kong-Jia Luo Ke-Xi Wang AmosÉla Bella Dong-Rong Situ Ji-Yang Chen Ting Lin Xavier B D’Journo Nuria M Novoa Alessandro Brunelli Hiran C Fernando Robert J Cerfolio Mahmoud Ismail Hong Yang 无 | 2020 | World Journal of Gastrointestinal Oncology2020，12，6： | 0 |
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