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| 1 | Cardiometabolic risk through an integrative classification combining physical activity and sedentary behavior in European adolescents:HELENA study显示文摘Purpose: This study aims to compare adolescents' cardiometabolic risk score through an integrative classification of physical activity(PA),which involves the combination of moderate-to-vigorous physical activity(MVPA) and sedentary behavior(SB).Methods: A cross-sectional study derived from the Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-Sectional Study database(2006-2008) was conducted in adolescents(n = 548; boys, 47.3%; 14.7 ± 1.2 years) from 10 European cities. MVPA and SB were objectively measured using accelerometry. Adolescents were divided into 4 categories according to MVPA(meeting or not meeting the international recommendations) and the median of SB time(above or below sex-and age-specific median) as follows: High-SB & Inactive, Low-SB & Inactive,High-SB & Active, and Low-SB & Active. A clustered cardiometabolic risk score was computed using the homeostatic model assessment, systolic blood pressure, triglycerides, total cholesterol/high-density lipoprotein cholesterol, sum 4 skinfolds, and cardiorespiratory fitness(CRF).Analyses of covariance were performed to discern differences on cardiometabolic risk scores among PA categories and each health component.Results: The cardiometabolic risk score was lower in adolescents meeting the MVPA recommendation and with less time spent in SB in comparison to the high-SB & Inactive group(p < 0.05). However, no difference in cardiometabolic risk score was established between High-SB or Low-SB groups in inactive adolescents. It is important to note that CRF was the only variable that showed a significant modification(higher)when children were compared from the category of physically inactive with 'active' but not from high-to low-SB.Conclusion: Being physically active is the most significant and protective outcome in adolescents to reduce cardiometabolic risk. Lower SB does not exhibit a significant and extra beneficial difference. | Carlos Cristi-Montero Palma Chillón Idoia Labayen José A.Casajus Marcela Gonzalez-Gross Jérémy Vanhelst Yannis Manios Luis A.Moreno Francisco B.Ortega Jonatan R.Ruiz | 2019 | Journal of Sport and Health Science2019，8，1： | 2 |
| 2 | A pilot study of atorvastatin treatment in dyslipemid, non‐alcoholic fatty liver patients显示文摘 | E.GóMEZ‐DOMíNGUEZ J. P.GISBERT J. A.MORENO‐MONTEAGUDO L.GARCíA‐BUEY R.MORENO‐OTERO | 2006 | Alimentary Pharmacology & Therapeutics2006，，11： | 1 |
| 3 | Glucosinolates in Broccoli Sprouts (Brassica oleracea var. italica) as Conditioned by Sulphate Supply during Germination显示文摘 | SantiagoPérez‐Balibrea Diego A.Moreno CristinaGarcía‐Viguera | 2010 | Journal of Food Science2010，，8： | 1 |
| 4 | Live liver donation: a prospective analysis of exclusion criteria for healthy and potential donors显示文摘 | E Moreno Gonzalez J.C Meneu Diaz I Garcia Garcia C Loinaz Segurola C Jimenez R Gomez M Abradelo A.Moreno Elola S Jimenez E Ferrero J Calvo A Manrique M.L Herrero | 2003 | Transplantation Proceedings2003，，5： | 1 |
| 5 | Serum levels of the novel adipokine isthmin-1 are associated with obesity in pubertal boys显示文摘Objectives To evaluate whether there is an association between the serum levels of the novel insulin-like adipokine isthmin-1(ISM1)and obesity-related phenotypes in a population of Spanish children and to investigate the plausible molecular alterations behind the alteration of the serum levels of this protein in children with obesity.Methods The study population is a sub-cohort of the PUBMEP research project,consisting of a cross-sectional population of 119 pubertal children with overweight(17 boys,19 girls),obesity(20 boys,25 girls),and normal weight(17 boys,21 girls).All subjects were classified into experimental groups according to their sex,obesity,and insulin resistance(IR)status.They were counted anthropometry,glucose and lipid metabolism,inflammation and cardiovascular biomarkers as well as isthmin-1(ISM1)serum levels.This population was intended as a discovery population to elucidate the relationship between obesity and ISM1 levels in children.Furthermore,the study population had blood whole-genome DNA methylation examined,allowing deepening into the obesity–ISM1 molecular relationship.Results Higher serum ISM1 levels were observed in boys with obesity than in normal weight(P=0.004)and overweight(P=0.007)boys.ISM1 serum levels were positively associated with body mass index(BMI)Z-score(P=0.005)and fat mass(P=0.058)and negatively associated with myeloperoxidase(MPO)(P=0.043)in boys.Although we did not find associations between ISM1 serum levels and metabolic outcomes in girls,which may indicate a putative sexual dimorphism,fat mass was positively associated in all children,including boys and girls(P=0.011).DNA methylation levels in two-enhancer-related CpG sites of ISM1(cg03304641 and cg14269097)were associated with serum levels of ISM1 in children.Conclusions ISM1 is associated with obesity in boys at the pubertal stage,elucidating how this protein might be of special relevance as a new biomarker of obesity in children.Further studies including a longitudinal design during puberty are needed. | Francisco Javier Ruiz‑Ojeda Augusto Anguita‑Ruiz Maria C.Rico Rosaura Leis Gloria Bueno Luis A.Moreno Mercedes Gil‑Campos Ángel Gil Concepción M.Aguilera | 2023 | World Journal of Pediatrics2023，19，9： | 1 |
| 6 | Immunohistochemically proven cytomegalovirus end‐organ disease in solid organ transplant patients: clinical features and usefulness of conventional diagnostic tests显示文摘 | A.Fica C.Cervera N.Pérez M.A.Marcos J.Ramírez L.Linares G.Soto M.Navasa F.Cofan M.J.Ricart F.Pérez‐Villa T.Pumarola A.Moreno | 2007 | Transplant Infectious Disease2007，，3： | 1 |
| 7 | System Identification and Discrete Nonlinear Control of Miniature Helicopters Using Backstepping显示文摘 | Ioannis A.Raptis KimonP.Valavanis Wilfrido A.Moreno | | 0，，0921： | 1 |
| 8 | The glutamate metabotropic receptor 5(GRM5)gene is associated with beef cattle home range and movement tortuosity显示文摘Background:The grazing behaviour of herbivores and their grazing personalities might in part be determined genetically,but there are few studies in beef cattle illustrating this.In this study,we investigated for first time the genetic variation within a candidate‘grazing gene',the glutamate metabotropic receptor 5 gene(GRM5),and tested associations between variation in that gene and variation in grazing personality behaviours(GP-behaviours)displayed by free-ranging cows during winter grazing in the steep and rugged rangelands of New Zealand.Mature beef cows(n=303,from 3 to 10 years of age)were tracked with global positioning system(GPS)and,with 5-minutes(min)relocation frequency,various GP-behaviours were calculated.These included horizontal and vertical distances travelled,mean elevation,elevation range,elevation gain,slope,home range and movement tortuosity,variously calculated using daily relocation trajectories with repeated measurements(i.e.,7 to 24 days(d))and satellite-derived digital elevation models(DEM).The different GP-behaviours were fitted into mixed models to ascertain their associations with variant sequences and genotypes of GRM5.Results:We discovered three GRM5 variants(A,B and C)and identified the six possible genotypes in the cattle studied.The mixed models revealed that A was significantly associated with elevation range,home range and movement tortuosity.Similarly,GRM5 genotypes were associated(P<0.05)to home range and movement tortuosity,while trends suggesting association(P<0.1)were also revealed for elevation range and horizontal distance travelled.Most GP-behaviour models were improved by correcting for cow age-class as a fixed factor.The analysis of GP-behaviours averaged per cow age-class suggests that grazing personality is fully established as beef cows reached 4 years of age.Home range and movement tortuosity were not only associated with GRM5 variation,but also negatively correlated with each other(r=-0.27,P<0.001).Conclusions:There seems to be a genetically determined trade-off between home range and movement tortuosity that may be useful in beef cattle breeding programmes aiming to improve the grazing distribution and utilisation of steep and rugged rangelands. | Cristian A.Moreno Garcia Huitong Zhou David Altimira Robyn Dynes Pablo Gregorini Sadeepa Jayathunga Thomas M.R.Maxwell Jonathan Hickford | 2023 | Journal of Animal Science and Biotechnology2023，14，1： | 0 |
| 9 | 马德里一个传染病科的移民结核病流行病学和临床特征显示文摘目的:对西班牙马德里一所三级医院1990年1月—2002年12月就诊的本国出生居民和移民进行结核病患病情况的比较分析。结果:全人群结核病(TB)年发病率从1990年的141/10万降低到2002年的73/10万;但是, TB疫情在移民群体中呈现上升趋势(从1990年的1%上升到2002年的27%),在1 353名移民中诊断TB98例(总的检出率为7.2%)。移民组TB患者的平均年龄30岁(6~77),男性占54%,大部分来自拉丁美洲(55%)和非洲(37%),在抵达西班牙后2年内被诊断的TB占69%。在接受检查的病人中,结核菌素阳性占88%。6%的病人合并艾滋病病毒感染,而本国出生居民组TB患者合并艾滋病病毒感染率为37%(P<0.001)。在2组中,肺结核都是最常见的类型(移民组79%,本国出生居民组80%),痰涂片阳性率不存在差异(分别是70%和75%)。移民组的原发耐药率显著高于本国出生居民组(移民组13%,本国出生居民组<6%,P<0.05)。移民组强化期都采用了四联药方案。总体上,82%的病人治愈,1例病人死于播散性疾病(1%),17例病人的随访数据不全(17%)。结论:移民组TB患病时的临床症状与本国出生居民组相似,但其发病的危险因素与本国出生居民组已知的危险因素不同。由于移民组的高原发耐药率,强化期的治疗应给予四联用药,直至药敏结果出来。 | S.Diz R.López-Vélez A.Moreno J.Fortún L.Moreno E.Gómez-Mampaso E.Navas S.Moreno 赖钰基 何广学 | 2008 | 国际结核病与肺部疾病杂志2008，3，1： | 0 |
| 10 | 未磺化物及其砜含量对单体物性的影响显示文摘人们发现用同种烷基苯在不同洗涤剂厂和工业磺化器上生产的磺酸盐溶解性(浊点)和粘度相差较大,其影响因素是磺化装置的操作条件。实际上,为控制终产品质量,不同的磺化装置都力求使磺酸中的游离油含量保持一定,其目的是控制游离油含量对直链烷基苯磺酸盐(LAS)物理性能的影响。然而,比游离油含量更重要的影响因素是游离油中的砜含量。 | A.Moreno 李凤起 | 1992 | 日用化学工业译丛1992，，5： | 0 |
| 11 | Input signal design to estimate interwell connectivities in mature fields from the capacitance-resistance model显示文摘Interwell connectivities are fundamental parameters required to manage waterfloods in oil reservoirs. Data-driven models, such as the capacitance-resistance model(CRM), are fast tools to estimate these parameters from time-correlations of input(injection rates) and output(production rates) signals. Noise and structure of the input time-series impose limits on the information that can be extracted from a given data-set. This work uses the CRM to study general prescriptions for the design of input signals that enhance the information content of injection/production data in the estimation of well-to-well interactions. Numerical schemes and general features of the optimal input signal strategy are derived for this problem. | Gustavo A.Moreno Larry W.Lake | 2014 | Petroleum Science2014，11，4： | 0 |
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