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191篇 您的检索式:作者名="A. Wright"
    题名 作者 年代 出处 被引量
1PLEIOTROPIC REGULATORY LOCUS 1 (PRL1) Integrates the Regulation of Sugar Responses with Isoprenoid Metabolism in Arabidopsis显示文摘在植物房间的 isoprenoids 的生合成从 mevalonate (MVA ) 在 cytosol 生产的先锋发生小径并且在由 methylerythritol 4 磷酸盐(MEP ) 的质体,小径,而是很少对协调两条小径的机制被知道。在 Arabidopsis thaliana 为如此的协作发信号的糖的重要性的证据被没有变化,在相关 MEP 小径抄本,蛋白质,或酶活动的层次显示出导出 MEP 的 isoprenoid 产品(叶绿素和类胡萝卜素) 的增加的累积的异种的描述这里提供。这异种被发现是新 loss-of-function 等位基因 PRL1 (多种的规章的地点 1 ) ,编码作为糖的一个全球管理者工作的保存 WD 蛋白质的基因,应力,和荷尔蒙回答,部分地由 SNF1 相关的蛋白质 kinases (SnRK1 ) 的抑制。与在 MVA 小径的主要的规章的酶的 phosphorylation 和 inactivation 的 SnRK1 kinases 的报导角色一致(hydroxymethylglutaryl 辅酶 -- reductase ) ,它的活动或蛋白质层次在 prl1 幼苗被减少。然而,导出 MVA 的结束产品(甾醇) 的累积在变异的幼苗是未改变的。蔗糖补充到野类型的幼苗 phenocopied prl1 变化以 isoprenoid 新陈代谢,建议观察 isoprenoid 显型从增加的糖累积导致 prl1 异种。在摘要, PRL1 看起来与糖,荷尔蒙,和压力回答协调 isoprenoid 新陈代谢。Ursula Flores-Perez Jordi Perez-Gil Marta Closa Louwrance R Wright Patricia Botella-Pavia Michael A. Phillips Albert Ferrer Jonathan Gershenzon Manuel Rodriguez-Concepcion 2010Molecular Plant2010,3,1:5
2Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure显示文摘Aram V. Chobanian George L. Bakris Henry R. Black William C. Cushman Lee A. Green Joseph L. Izzo Daniel W. Jones Barry J. Materson Suzanne Oparil Jackson T. Wright Edward J. Roccella 2003Hypertension: Journal of The American Heart Association2003,,6:4
3WROUGHT TiAl ALLOY DESIGN显示文摘Empirical improvements made in cast alloys have led to gamma alloys which are a viable materials technology, and to the development of various applications for gas turbine engines, as well as automotive engines. For wrougth alloys, over the last seven years the author et al have made extensive efforts to remove their deficiencies, and to achieve an improved balance of properties, across three interrelated task areas. The first effort was directed toward understanding fundamentals, such as phase relations, microstructure evolution, and microstructure property relationships. The second task was then directed to improve the balance of properties through designing refined lamellar microstructures and microalloying. The third effort was to explore the production methods to develop desired microstructures and to optimize the alloy compositions. This paper discusses the progress made from the last two efforts.Young Won Kim Materials and Manufacturing Directorate, Air Force Research Laboratory Wright Patterson AFB, OH 45433, U. S. A. 1999中国有色金属学会会刊:英文版1999,9,S1:3
4荷兰不同来源耐多药结核病例中二线耐药情况显示文摘背景:荷兰。目的:调查不同地理来源的耐多药结核病人耐二线药情况及其相关因素。方法:对荷兰1993年1月至2007年10月间耐多药结核病人分离菌株的实验室数据进行回顾性研究。结果:发现的153例耐多药结核病人中,18例(12%)为荷兰本国人。对其中的131例进行二线药物敏感性实验,有28例(21%)为耐二线药,且大部分为单一耐药(24/28(86%));9例耐丙硫异烟胺(PTH),6例耐对氨基水杨酸,4例耐阿米卡星(ASK),4例耐环丙沙星,1例耐环丝氨酸)。有4例耐多药结核病人耐多种二线药;2例为广泛耐药的牛型结核分枝杆菌。在所有耐多药结核病人中,来自欧洲和中亚者二线耐药较普遍,且涉及的药物也较广泛。来自非洲和美洲者主要耐PTH,而来自东南亚者主要耐AMK。结论:在荷兰,耐多药结核病人中二线耐药情况并不普遍。大部分二线耐药发生在移民当中,来源于不同的地域,病人耐药情况也不同。J. van Ingen M. J. Boeree A. Wright T. van der Laan P. N. R. Dekhuijzen D. vanSoolingen 刘青(译) 何广学(审校) 2009国际结核病与肺部疾病杂志2009,4,2:3
5Effect of probiotic treatment on deranged neutrophil function and cytokine responses in patients with compensated alcoholic cirrhosis显示文摘Vanessa Stadlbauer Rajeshwar P. Mookerjee Stephen Hodges Gavin A.K. Wright Nathan A. Davies Rajiv Jalan 2008Journal of Hepatology2008,,6:2
6The effect of social context and social scale on the perception of relationships in monk parakeets显示文摘Elizabeth A. HOBSON Darlene J. JOHN Tiffany L. MCINTOSH Michael L. AVERY Timothy F. WRIGHT 2015Current Zoology2015,61,1:2
7Gliotoxin Stimulates the Apoptosis of Human and Rat Hepatic Stellate Cells and Enhances the Resolution of Liver Fibrosis in Rats显示文摘Matthew C. Wright Razo Issa David E. Smart Nathan Trim Graeme I. Murray John N. Primrose Michael J.P. Arthur John P. Iredale Derek A. Mann 2001Gastroenterology2001,,3:2
8Four-Year Recurrence Rate and Prognosis of the Apical Ballooning Syndrome显示文摘Ahmad A. Elesber Abhiram Prasad Ryan J. Lennon R. Scott Wright Amir Lerman Charanjit S. Rihal 2007Journal of the American College of Cardiology2007,,5:2
9Human resources and the resource based view of the firm显示文摘Patrick M. Wright Benjamin B. Dunford Scott A. Snell 2001Journal of Management2001,,6:2
10Field Cancerization in the Intestinal Epithelium of Patients With Crohn’s Ileocolitis显示文摘Susan Galandiuk Manuel Rodriguez–Justo Rosemary Jeffery Anna M. Nicholson Yong Cheng Dahmane Oukrif George Elia Simon J. Leedham Stuart A.C. McDonald Nicholas A. Wright Trevor A. Graham 2012Gastroenterology2012,,4:2
11Clonality, Founder Mutations, and Field Cancerization in Human Ulcerative Colitis–Associated Neoplasia显示文摘Simon J. Leedham Trevor A. Graham Dahmane Oukrif Stuart A.C. McDonald Manuel Rodriguez–Justo Rebecca F. Harrison Neil A. Shepherd Marco R. Novelli Janusz A.Z. Jankowski Nicholas A. Wright 2009Gastroenterology2009,,2:2
12Participation in cooperative prey capture and the benefits gained from it are associated with individual personality显示文摘In animal societies, behavioral idiosyncrasies of the individuals often guide which tasks theyshould perform. Such personality-specific task participation can increase individual task efficiency,thereby improving group performance. While several recent studies have documented group-levelbenefits of within-group behavioral (i.e., personality) diversity, how these benefits are realized atthe individual level is unclear. Here we probe the individual-level benefits of personality-driven taskparticipation in the social spider Stegodyphus dumicola. In S. dumicola, the presence of at leastone highly bold individual catalyzes foraging behavior in shy colony members, and all group con-stituents heavily compete for prey. We assessed boldness by examining how quickly spidersresumed normal movement after a simulated predator attack. We test here whether (1) participantsin collective foraging gain more mass from prey items and (2) whether bold individuals are less re-sistant to starvation than shy spiders, which would motivate the bold individuals to forage more.Next, we assembled colonies of shy spiders with and without a bold individual, added one preyitem, and then tracked the mass gain of each individual spider after this single feeding event. Wefound that spiders that participated in prey capture (whether bold or shy) gained more mass thannonparticipators, and colonies containing a single bold spider gained more total mass than purelyshy colonies. We also found that bold spiders participated in more collective foraging events andwere more susceptible to starvation than shy spiders, suggesting that the aggressive foraging ofbold individuals may represent a strategy to offset starvation risk. These findings add to the bodyof evidence that animal personality can shape social organization, individual performance, andgroup success.James L.L. LICHTENSTEIN Colin M. WRIGHT Lauren P. LUSCUSKIE Graham A. MONTGOMERY PINTER-WOLLMAN Jonathan N. PRUITT 2017Current Zoology2017,63,5:2
13An international, multicenter phase II trial of bortezomib in patients with hepatocellular carcinoma显示文摘George P. Kim Michelle R. Mahoney Daniel Szydlo Tony S. K. Mok Robert Marshke Kyle Holen Joel Picus Michael Boyer Henry C. Pitot Joseph Rubin Philip A. Philip Anna Nowak John J. Wright Charles Erlichman 2012Investigational New Drugs2012,,1:2
14QTL analysis of leaf morphology in tetraploid Gossypium (cotton)显示文摘C. Jiang R. J. Wright S. S. Woo T. A. DelMonte A. H. Paterson 2000TAG Theoretical and Applied Genetics (-)2000,,3:1
15Mass Spectrometry and reverse phase HPLC techniques for the identification of degraded fossil pigments in lake sediments and their application in palaeolimnology显示文摘Dominic A. Hodgson Simon W. Wright Noel Davies 1997Journal of Paleolimnology1997,,4:1
16Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity 1 1 Edited by F.E.Cohen显示文摘Deborah S. Wuttke Mark P. Foster David A. Case Joel M. Gottesfeld Peter E. Wright 1997Journal of Molecular Biology1997,,1:1
17Genetic analysis of the components of winterhardiness in barley (Hordeum vulgare L.)显示文摘A. Pan P. M. Hayes F. Chen T. H. H. Chen T. Blake S. Wright I. Karsai Z. Bed? 1994Theoretical and Applied Genetics (-)1994,,7:1
182012 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing the 2011 Focused Update)显示文摘Hani Jneid Jeffrey L. Anderson R. Scott Wright Cynthia D. Adams Charles R. Bridges Donald E. Casey Steven M. Ettinger Francis M. Fesmire Theodore G. Ganiats A. Michael Lincoff Eric D. Peterson George J. Philippides Pierre Theroux Nanette K. Wenger James P 2012Journal of the American College of Cardiology2012,,7:1
19Structure and morphology of propylthiol-functionalised mesoporous silicas templated by non-ionic triblock copolymers显示文摘Robert P. Hodgkins Alfonso E. Garcia-Bennett Paul A. Wright 2004Microporous and Mesoporous Materials2004,,1:1
20Exocrine pancreas trans-differentiation to hepatocytes—A physiological response to elevated glucocorticoid in vivo显示文摘Karen Wallace Carylyn J. Marek Richard A. Currie Matthew C. Wright 2009Journal of Steroid Biochemistry and Molecular Biology2009,,1:1
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