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| 1 | Intra-abdominal pressure:Time ripe to revise managementguidelines of acute pancreatitis?显示文摘AIM: To systematically review evidence on pathophysiology of intra-abdominal pressure(IAP) in acute pancreatitis(AP) with its clinical correlates. METHODS: Systematic review of available evidence in English literature with relevant medical subject heading terms on Pub Med, Medline and Scopus with further search from open access sources on internet as suggested by articles retrieved. RESULTS: Intra-abdominal hypertension(IAH) is increasingly gaining recognition as a point of specific intervention with potential to alter disease outcome and improve mortality in AP. IAH can be expected in at least 17% of patients presenting with diagnosis of AP to a typical tertiary care hospital(prevalence increasing to 50% in those with severe disease). Abdominal compartment syndrome can be expected in at least 15% patients with severe disease. Recent guidelines on management of AP do not acknowledge utility of surveillance for IAP other than those by Japanese Society of Hepato-BiliaryPancreatic Surgery. We further outline pathophysiologic mechanisms of IAH; understanding of which advances our knowledge and helps to coherently align common observed variations in management related conundrums(such as fluid therapy, nutrition and antibiotic prophylaxis) with potential to further individualize treatment in AP. CONCLUSION: We suggest that IAP be given its due place in future practice guidelines and that recommendations be formed with help of a broader panel with inclusion of clinicians experienced in management of IAH. | jiten jaipuria vimal bhandari avneet singh chawla mohit singh | 2016 | World Journal of Gastrointestinal Pathophysiology2016,7,1: | 14 |
| 2 | Endoscopic retrograde cholangiopancreatography in cirrhosis-a systematic review and meta-analysis focused on adverse events显示文摘AIM To investigate indications and outcomes of endoscopic retrograde cholangiopancreatography(ERCP) in cirrhotics, especially adverse events. Patients with cirrhosis undergoing ERCP are believed to have increased risk. However, there is a paucity of literature describing the indications and outcomes of ERCP procedures in patients with cirrhosis, especially focusing on adverse events.METHODS We performed a systematic appraisal of major literature databases, including PubMed and EMBASE, with a manual search of literature from their inception until April 2017.RESULTS A total of 6,505 patients from 15 studies were analyzed(male ratio 59%, mean age 59 years), 11% with alcoholic and 89% with non-alcoholic cirrhosis, with 56.2% Child-Pugh class A, and 43.8% class B or C. Indications for ERCP included choledocholithiasis 60.9%, biliary strictures 26.2%, gallstone pancreatitis 21.1% and cholangitis 15.5%. Types of interventions included endoscopic sphincterotomy 52.7%, biliary stenting 16.7% and biliary dilation 4.6%. Individual adverse events included hemorrhage in 4.58%(95%CI: 2.77-6.75%, I^2 = 85.9%), post-ERCP pancreatitis(PEP) in 3.68%(95%CI: 1.83-6.00%, I^2 = 89.5%), cholangitis in 1.93%(95%CI: 0.63-3.71%, I^2 = 87.1%) and perforation in 0.00%(95%CI: 0.00-0.23%, I^2 = 37.8%). Six studies were used for comparison of ERCPrelated complications in cirrhosis vs non-cirrhosis, which showed higher overall rates of complications in cirrhosis patients with pooled OR of 1.63(95%CI: 1.27-2.09, I2 = 65%): higher rates of hemorrhage with OR of 2.05(95%CI: 1.62-2.58, I^2 = 2.1%) and PEP with OR of 1.33(95%CI: 1.04-1.70, I2=65%), but similar cholangitis rates with OR of 1.23(95%CI: 0.67-2.26, I^2 = 44.3%).CONCLUSION There is an overall higher rate of adverse events related to ERCP in patients with cirrhosis, especially hemorrhage and PEP. A thorough risk/benefit assessment should be performed prior to undertaking ERCP in patients with cirrhosis. | Shailender Singh Mashiana Amaninder Singh Dhaliwal Harlan Sayles Banreet Dhindsa Ji Won Yoo Qing Wu shailender singh Ali A Siddiqui Gordon Ohning Mohit Girotra Douglas G Adler | 2018 | World Journal of Gastrointestinal Endoscopy2018,10,11: | 6 |
| 3 | Association of NFKB1 gene polymorphism (rs28362491) with levels of inflammatory biomarkers and susceptibility to diabetic nephropathy in Asian Indians显示文摘AIM To investigate the association of NFKB1 gene-94 ATTG insertion/deletion(rs28362491) polymorphism with inflammatory markers and risk of diabetic nephropathy in Asian Indians.METHODS A total of 300 subjects were recruited(100 each), normoglycemic,(NG); type 2 diabetes mellitus(T2DM) without any complications(DM) and T2 DM with diabetic nephropathy [DM-chronic renal disease(CRD)]. Analysis was carried out by polymerase chain reaction-restriction fragment length polymorphism and ELISA. Pearson's correlation, analysis of variance and logistic regression wereused for statistical analysis.RESULTS The allelic frequencies of-94 ATTG insertion/deletion were 0.655/0.345(NG), 0.62/0.38(DM) and 0.775/0.225(DM-CRD). The-94 ATTG ins allele was associated with significantly increased levels of urinary monocyte chemoattractant protein-1(u MCP-1); u MCP-1(P = 0.026) and plasma tumor necrosis factor-alpha(TNF-α); TNF-α(P = 0.030) and almost doubled the risk of diabetic nephropathy(OR = 1.91, 95%CI: 1.080-3.386, P = 0.025).CONCLUSION-94 ATTG ins/ins polymorphism might be associated with increased risk of developing nephropathy in Asian Indian subjects with diabetes mellitus. | Amar Gautam Stuti Gupta Mohit Mehndiratta Mohini Sharma Kalpana Singh Om P Kalra Sunil Agarwal Jasvinder K Gambhir | 2017 | World Journal of Diabetes2017,8,2: | 4 |
| 4 | An unusual cause of radial nerve palsy显示文摘Neurapraxia 经常发生 intraoperatively 跟随拖拉损害到神经,导致通常在 5-30 星期内恢复的光线的神经麻痹。在我们的情况中,我们操作了一远侧三分之一个肱骨的柄断裂并且与 4.5 修理了它;公里限制了接触动态压缩板。手足的远侧的神经与血管的地位在恢复房间里手术后地被估计并且被发现未经触动并且光线的神经的所有感觉马达的功能是正常的。在第二手术后的天,跟随吸排水管移动和调味品,与手腕落下一起的耐心的发达立即的光线的神经麻痹。我们考察了文学并且没为神经麻痹发现明显的原因并且当在否定压力移开吸排水管时,断定它由于对光线的神经的拖拉损害。 | Hemendra Kumar Agrawal Vipin Khatkar Mohit Garg Balvinder Singh Ashish Jaiman Vinod Kumar Sharma | 2014 | Chinese Journal of Traumatology2014,17,3: | 2 |
| 5 | Rare variant of mixed total anomalous pulmonary venous connection 显示文摘 | Singh J Mohite PN Rana SS | 2012 | Cardio- vasc Dis Res2012,3,: | 1 |
| 6 | A modifie intrinsic enriched element free Galerkin method for multiple crack simulation显示文摘 | Singh I V Mishra B K Pant Mohit | 2010 | Materials and Design2010,31,: | 1 |
| 7 | Analysis of Different Privacy Preserving Cloud Storage Frameworks 显示文摘 | Rajeev Bedi Mohit Marwaha2 Tajinder Singh | 2011 | International Journal of Computer Science & Information Technology (IJCSIT)2011,3,6: | 1 |
| 8 | A modified intrinsic enriched element free Galerkin method for multiple cracks simulation显示文摘 | Singh I V Mishra B K Pant Mohit | 2010 | Materials and Design2010,31,: | 1 |
| 9 | First principles calculation of optical properties of BaWO4 : Astudy by full potential method 显示文摘 | MOHIT T N SINGH S G CHAUHAN A K GADKARI S C | 2010 | Physical B2010,45,: | 1 |
| 10 | A modified intrinsic enriched element free Galerkin method for multiple cracks simulation 显示文摘 | SINGH I V MISHRA B K MOHIT P | 2010 | Materials & Design2010,31,1: | 1 |
| 11 | Ex- ploring potential of micro-Raman spectroscopy for corre- lating graphitic distortion in carbon fibers with stresses in erosive wear studies of PEEK composites 显示文摘 | Mohit Sharma Jayashree Bijwe Kuldeep Singh | 2011 | Wear2011,270,11: | 1 |
| 12 | Graphene: from synthesis to engineering to biosensor applications显示文摘 | Jagpreet SINGH Aditi RATHI Mohit RAWAT Manoj GUPTA | 2018 | Frontiers of Materials Science2018,12,1: | 1 |
| 13 | An enrichment based new criterion for the simulation of multiple interacting cracks using element free Galerkin method显示文摘 | SINGH I V MISHRA B K PANT MOHIT | | 0,,02: | 1 |
| 14 | Randomized, double-blinded, placebo-controlled trial evaluating simethicone pretreatment with bowel preparation during colonoscopy显示文摘BACKGROUND The presence of small air bubbles and foam are an impediment to a successful colonoscopy. They impair an endoscopist’s view and diminish the diagnostic accuracy of the study. This has been particularly noted to be of concern with the switch to lower volume polyethylene glycol (PEG) and bisacodyl combination preparation. AIM To evaluate the effect of oral simethicone addition to bowel preparation on intraluminal bubbles reduction during colonoscopy. METHODS Described is a prospective, randomized, multi-center, double-blinded, placebocontrolled study to evaluate the use of premixed simethicone formulation with split-regimen, low-volume PEG-bisacodyl combination bowel preparation for 168 outpatients undergoing screening, surveillance, and diagnostic colonoscopies. Primary outcome includes evaluation of bubbles during colonoscopy graded using the Intraluminal Bubbles Scale. Secondary outcomes include evaluation of the Boston Bowel Preparation Scale (BBPS), total number of polyps, polyp size differentiation, polyp laterality, adenoma detection, mass detection, cecal insertion time, withdrawal time, and patient-reported adverse events. RESULTS Higher Intraluminal Bubbles grades III and IV (less than 75% of the mucosa cleared of bubbles/foam requiring intervention with simethicone infused wash) were detected in the placebo group [Simethicone n = 4/84 vs Placebo n = 20/84 (P = 0.007)]. BBPS total score was 7.42 [standard deviation (SD)=± 1.51] in the simethicone group and 7.28 (SD =± 1.44) in the placebo group (P = 0.542) from a total of 9. Significantly higher number of adenomas were detected in the simethicone group (P = 0.001). CONCLUSION The addition of simethicone to bowel preparation is well advised for its antifoaming properties. The results of this study suggest that addition of oral simethicone can improve bowel wall visibility. | Mohit Rishi Jaskarin Kaur Mark Ulanja Nicholas Manasewitsch Molly Svendsen Abubaker Abdalla Shashank Vemala Julie Kewanyama Karmjit Singh Nirmal Singh Nageshwara Gullapalli Eric Osgard | 2019 | World Journal of Gastrointestinal Endoscopy2019,11,6: | 1 |
| 15 | Rare variant of mixed total anomalous pulmonary venous connection显示文摘 | Singh J Mohite PN Rana SS | 2012 | J Cardiovasc Dis Res2012,3,3: | 1 |
| 16 | Spontaneous renal forniceal rupture due to advanced cervical carcinoma with obstructive uropathy显示文摘 | Iqbal Singh Mohit Joshi Gopesh Mehrotra | 2009 | Archives of Gynecology and Obstetrics2009,,6: | 1 |
| 17 | Ef- ficacy of Low-Level Laser Therapy in Treatment of Recurrent Aphthous Ulcers - A Sham Controlled, Split Mouth Follow Up Study显示文摘 | Hersheal Aggarwal Mohit Pal Singh Prashant Nahar | 2014 | J Clin Diagn Res2014,8,2: | 1 |
| 18 | Wooden stick penetration from the perineal region up to the thorax显示文摘BACKGROUND: Penetrating injuries of the perineum are rare but very dangerous. Since the genitourinary and colorectal organs may be injured, how to evaluate surgical management of the injury is very important.METHODS: The present report presents a case of penetrating injury of the perineum by a wooden stick when the patient fell on the upright wooden stick from a tree. The three feet long stick entered the perineal region just left lateral to the anal opening. Upon reaching the thoracic cavity, it broke and only a foot stick was left in the subcutaneous plane. These injuries are potentially serious with risk of damage to multiple organs. Exploratory laprotomy was done, and bladder injury was repaired. The entry wound and the track of stick was thoroughly washed and allowed for secondary intention healing.RESULTS: The post operative period was uneventful and the patient recovered fully.CONCLUSION: Meticulous evaluation and surgical management of perineal injuries are the key to prevent devastating complications. | Khem Pal Singh Anil Kumar Joshi Mohit Kumar Joshi Chitra Joshi Mridu Singh Vikram Singh | 2015 | World Journal of Emergency Medicine2015,6,4: | 0 |
| 19 | An internet of things assisted drone based approach to reduce rapid spread of COVID-19显示文摘With the quick spread of pandemic disease,many individuals have lost their lives across different parts of the world.So,the need for a novel approach or model to overcome the problem becomes a necessity.In this paper,a mechanism is proposed called DBCMS(Drone Based Covid-19 Medical Service)for the safety of medical em-ployees who are prone to Covid-19 infection.The proposed mechanism can effectively improve the treatment process of Covid-19 patients.Drones are nowadays commonly used in the field of medical emergency situations.The proposed model in this paper uses drone service to reduce the risk of infection to the doctors or other medical staff,thereby preventing the disease spread.This paper further assumes that the primary step is to isolate people at their home instead of admitting them to the hospitals,also called a situation of lockdown or curfew.Thus,in this way,the spread can be significantly reduced across the globe if DBCMS approach is implemented at cluster level. | Mohit Angurala Manju Bala Sukhvinder Singh Bamber Rajbir Kaur Prabhdeep Singh | 2020 | Journal of Safety Science and Resilience2020,1,1: | 0 |
| 20 | Cosmetic arm lengthening with monorail fixator显示文摘 | Hemendra Kumar Agrawal Balvinder Singh Mohit Garg Vipin Khatkar Sumit Batra Vinod Kumar Sharma | 2015 | Chinese Journal of Traumatology2015,18,3: | 0 |