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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Oral refeeding in mild acute pancreatitis:An old challenge显示文摘Although the idea that pancreas rest has long been considered as a very relevant topic in acute pancreatitis (AP)therapy,the right time and type of diet to be offered to patients recovering from an acute attack are a great challenge to clinicians who treat this condition.Fortunately,the last decade was noted for several trials looking for the best answer to the question:'when and how to start oral refeeding in AP?'It is well known that 80%of patients present with mild disease characterized by usually uncomplicated clinical course are managed with pancreatic rest through nil per oral;while the use of specific nutritional intervention is an exception.Therefore,mild AP has been the most investigated form of AP and researchers have tried different kind of meals to offer calories and reduce costs by shortening hospitalization time.Usually in mild AP,the oral refeeding is introduced between the first 3 d and 7 d after hospitalization but,the type of diet and patients’tolerance have been scrutinized in detail with mixed results.Although 20%to 25%have pain recurrence requiring nutritional support and greater time of hospitalization,most patients seem to tolerate oral refeeding well.We propose analyzing the most recent investigations of this matter and their conclusions to develop a better understanding of the management of AP. | Júlio Maria F Chebli Pedro D Gaburri Liliana A Chebli | 2011 | World Journal of Gastrointestinal Pathophysiology2011，2，6： | 2 |
| 3 | 迷走神经刺激和意识水平显示文摘研究表明,植物人状态的患者皮质皮质间和丘脑-皮质间远程通路中断.自我恢复的神经特征与丘脑-皮质活动的增加和前额叶功能连接改善有关.本研究通过刺激-位植物状态患者的植物神经评估来评估丘脑-皮质刺激的作用.该案例研究报道了-名35岁的有创伤性脑损伤史的男性,他15年来-直处于植物人状态.基线评估包括行为、脑电图和18F-FDGPET记录.然后患者接受了手术植入迷走神经刺激器,刺激增加至最大强度为1.5mA. | 李建华 Corazzol M Lio G Lefevre A | 2017 | 中国康复2017，32，6： | 2 |
| 4 | Experimental active control bench tests on controller units 显示文摘 | Carotti A Lio G | 1991 | Journal of Engineering Structures1991，13，： | 1 |
| 5 | Chromosomal relationships among cultivars of Citrus reticulata Blanco, its hybrids and related species显示文摘 | M. T. M. N. Cornélio A. R. S. Figueir?a K. G. B. Santos R. Carvalho W. S. Soares Filho M. Guerra | 2003 | Plant Systematics and Evolution (-)2003，，1： | 1 |
| 6 | Environmentally Benign Polyester Synthesis by Room Temperature Direct Polycondensation of Dicarboxylie Acid and Diol 显示文摘 | A Takasu Y lio Y Oishi | 2005 | Maeromol ecules2005，38，： | 1 |
| 7 | Developmental changes in membrane properties and postsynaptic currents of granule cells in rat dentate gyrus显示文摘 | Liu Y B Lio P A Pastemak J F | 1996 | J Neurophysiol1996，76，2： | 1 |
| 8 | Comparison of dermatology and aller- gy guidelines for atopic dermatitis management 显示文摘 | Mohan G C Lio P A | 2015 | JAMA Dermatol2015，151，9： | 1 |
| 9 | Reinforced Concrete Jacketing-Interface Influence on Cyclic Loading Response显示文摘 | Júlio Eduardo N B S Branco Fernando A B | 2008 | ACI Structural Journal2008，，4： | 1 |
| 10 | MOLECULAR IMAGING OF THERMOCHROMIC CARBOHYDRATE-MODIFIED POLYDIACETYLENE THIN FILMS显示文摘 | Lio A Reichert A Ahn D J | | 0，，： | 1 |
| 11 | Inflammation, genetics, and longevity: further studies on the pro- tective effects in men of IL-10-1082 promoter SNP and its interaction with TNF-alpha-308 promoter SNP 显示文摘 | Lio D Scola L Crivello A | 2003 | J Med Genet2003，40，4： | 1 |
| 12 | Genotype frequencies of the+874T->A single nucleotide polymorphism in the first intron of the interferon-gamma gene in a sample of Sicilian patients affected by tuberculosis显示文摘 | Lio D Marino V Serauto A | 2002 | Eur J Immunogenet2002，29，5： | 1 |
| 13 | Environmentally Benign Polyester Synthesis by Room Temperature Direct Polycondensation of Dicarboxylic Acid and Diol显示文摘 | TAKASU A LIO Y OISHI Y | 2005 | Macromol Ecules2005，，8： | 1 |
| 14 | Decreased expression of microRNA-143 and -145 in human gastric cancers显示文摘 | Takagi T lio A Nakagawa Y | 2009 | Oncology2009，77，1： | 1 |
| 15 | Lactate detection by MRS in mitochondrial encephalopathy: optimization of technical parameters 显示文摘 | Jos e da Rocha A TO lio Braga F Carlos Martins Maia A Jr | 2008 | Neuroimaging2008，18，1： | 1 |
| 16 | Image restoration using digital inpainting and noise removal显示文摘 | Celia A Zorzo Barcelosa Marcos Aure'lio Batista | 2007 | Image and Vision Computing2007，25，： | 1 |
| 17 | Comparison of Superior Gluteal Artery Musculocutaneous and Superior Gluteal Artery Perforator Flaps for Microvascular Breast Reconstruction显示文摘 | Boyd J B Gelfand M Da Lio A | 2009 | Plast Reconstr Surg2009，123，6： | 1 |
| 18 | Comminution of silicon carbide powder in a planetary mill显示文摘 | MARIA Aparecida P dos Santos Ce LIO A Costa | 2006 | Powder Technology2006，169，： | 1 |
| 19 | Immediate free flap reconstruction for advanced-stage breast cancer:Is it safe显示文摘 | CRISERA C A CHANG E I DA LIO A L | | 0，，01： | 1 |
| 20 | Experimental active control bench tests on controller units显示文摘 | LIO G | 1991 | Journal of Engineering Structures1991，13，： | 1 |
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