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| 1 | 农村政策执行协商会影响农民的政策满意度吗?显示文摘本文基于2013年开展的农业部农村固定观察点'‘三农’政策执行情况'农户调查数据,利用有序Probit模型从基础设施建设、土地整理等角度考察了农村政策执行协商对农民政策满意度的影响,并借助双变量有序Probit模型减轻了可能存在的内生性的问题。研究发现,扩大农户参与政策执行协商,对农户的政策满意度有显著的正向影响,该结论从检验方法、变量定义等方面均具有很好的稳健性。研究表明,完善农村基层协商民主制度,推进村级事务的农户协商,能有效缓解农村社会张力,避免激化基层社会矛盾,提高农村公共治理水平。 | 吴比 Ziming Li 杨汝岱 彭超 | 2016 | 中国农村经济2016,,4: | 16 |
| 2 | The dimension and morphology of alveolar bone at maxillaryanterior teeth in periodontitis: a retrospective analysis usingCBCT显示文摘The morphology of the alveolar bone at the maxillary anterior teeth in periodontitis patients was evaluated by cone-beam computed tomography(CBCT) to investigate the distribution of alveolar defects and provide guidance for clinical practice. Ninety periodontitis patients and 30 periodontally healthy individuals were selected to determine the morphology of the alveolar bone at the maxillary anterior teeth according to the degree of bone loss, tooth type, sex and age. The differences in the dimensions between periodontitis patients and healthy individuals were compared, and the distribution of alveolar bone defects was analyzed.A classification system was established regarding the sagittal positions and angulations of the teeth. The buccal residual bone was thicker and the lingual bone was thinner in the periodontitis patients than in the periodontally healthy individuals, and there were differences between the different tooth types, sexes and age subgroups. The buccal undercut was close to the alveolar ridge, while fenestration was reduced and the apical bone height was higher in periodontitis patients than in periodontally healthy individuals.The apical bone height increased with the aggravation of bone loss and age. The proportions of different sagittal positions changed with the aggravation of bone loss. Moreover, the teeth moved more buccally regarding the positions of the maxillary anterior teeth.The morphology of the alveolar bone at the maxillary anterior teeth differed between periodontitis patients and healthy individuals,and the differences were related to the degree of bone loss, tooth type, sex and age. | Xue Zhang Yuchao Li Ziming Ge Haijiao Zhao Lei Miao Yaping Pan | 2020 | International Journal of Oral Science2020,12,1: | 10 |
| 3 | Short-term local prediction of wind speed and wind power based on singular spectrum analysis and locality-sensitive hashing显示文摘With the growing penetration of wind power in power systems, more accurate prediction of wind speed and wind power is required for real-time scheduling and operation. In this paper, a novel forecast model for shortterm prediction of wind speed and wind power is proposed,which is based on singular spectrum analysis(SSA) and locality-sensitive hashing(LSH). To deal with the impact of high volatility of the original time series, SSA is applied to decompose it into two components: the mean trend,which represents the mean tendency of the original time series, and the fluctuation component, which reveals the stochastic characteristics. Both components are reconstructed in a phase space to obtain mean trend segments and fluctuation component segments. After that, LSH is utilized to select similar segments of the mean trend segments, which are then employed in local forecasting, so that the accuracy and efficiency of prediction can be enhanced. Finally, support vector regression is adopted forprediction, where the training input is the synthesis of the similar mean trend segments and the corresponding fluctuation component segments. Simulation studies are conducted on wind speed and wind power time series from four databases, and the final results demonstrate that the proposed model is more accurate and stable in comparison with other models. | Ling LIU Tianyao JI Mengshi LI Ziming CHEN Qinghua WU | 2018 | Journal of Modern Power Systems and Clean Energy2018,6,2: | 10 |
| 4 | Crust and Upper Mantle Electrical Resistivity Structure in the Panxi Region of the Eastern Tibetan Plateau and Its Significance显示文摘The Panxi region is located in the frontal zone of positive squeezing subduction and side squeezing shearing between the Indian plate and the Eurasian plate. The long-period magnetotelluric(LMT) and broadband magnetotelluric(MT) techniques are both used to study the deep electrical conductivity structure in this region; magnetic and gravity surveys are also performed along the profile. According to the 2-D resistivity model along the Yanyuan-Yongshan profile,a highconductivity layer(HCL) exists widely in the crust,and a high-resistivity block(HRB) exists widely in the upper mantle in general,as seen by the fact that a large HCL exists from the western Jinpingshan tectonic zone to the eastern Mabian tectonic zone in the crust,while the HRB found in the Panxi tectonic zone is of abnormally high resistivity in that background compared to both sides of Panxi tectonic zone. In addition,the gravity and magnetic field anomalies are of high value. Combined with geological data,the results indicate that there probably exists basic or ultrabasic rock with a large thickness in the lithosphere in the Panxi axial region,which indicates that fracture activity once occurred in the lithosphere. As a result,we can infer that the high-resistivity zone in the Panxi lithosphere is the eruption channel for Permian Emeishan basalt and the accumulation channel for basic and ultrabasic rock. The seismic sources along the profile are counted according to seismic record data. The results indicate that the most violent earthquake sources are located at the binding site of the HRB and the HCL,where the tectonic activity zone is generally acknowledged to be; however,the earthquakes occurring in the HCL are not so violent,which reflects the fact that the HCL is a plastic layer,and the fracture threshold of a plastic layer is low generally,making high stress difficult to accumulate but easy to release in the layer. As a result,a higher number of smaller earthquakes occurred in the HCL at Daliangshan tectonic zone,and violent earthquakes occurred at the binding site of high- and low-resistivity blocks at the Panxi tectonic zone. | ZHANG Gang WANG Xuben FANG Hui GUO Ziming ZHANG Zhaobin LUO Wei CAI Xuelin LI Jun LI Zhong WU Xing | 2015 | Acta Geologica Sinica(English Edition)2015,89,2: | 9 |
| 5 | Inhibiting collagen Ⅰ production and tumor cell colonization in the lung via miR-29a-3p loading of exosome-/liposome-based nanovesicles显示文摘The lung is one of the most common sites for cancer metastasis.Collagens in the lung provide a permissive microenvironment that supports the colonization and outgrowth of disseminated tumor cells.Therefore,down-regulating the production of collagens may contribute to the inhibition of lung metastasis.It has been suggested that mi R-29 exhibits effective anti-fibrotic activity by negatively regulating the expression of collagens.Indeed,our clinical lung tumor data shows that mi R-29 a-3 p expression negatively correlates with collagen I expression in lung tumors and positively correlates with patients’outcomes.However,suitable carriers need to be selected to deliver this therapeutic mi RNA to the lungs.In this study,we found that the chemotherapy drug cisplatin facilitated mi R-29 a-3 p accumulation in the exosomes of lung tumor cells,and this type of exosomes exhibited a specific lung-targeting effect and promising collagen down-regulation.To scale up the preparation and simplify the delivery system,we designed a lung-targeting liposomal nanovesicle(by adjusting the molar ratio of DOTAP/cholesterol-mi RNAs to 4:1)to carry mi R-29 a-3 p and mimic the exosomes.This liposomal nanovesicle delivery system significantly down-regulated collagen I secretion by lung fibroblasts in vivo,thus alleviating the establishment of a pro-metastatic environment for circulating lung tumor cells. | Yan Yan Cancan Du Xixi Duan Xiaohan Yao Jiajia Wan Ziming Jiang Zhongyu Qin Wenqing Li Longze Pan Zhuoyu Gu Fazhan Wang Ming Wang Zhihai Qin | 2022 | Acta Pharmaceutica Sinica B2022,12,2: | 7 |
| 6 | COHERENT, REGULAR AND SIMPLE SYSTEMS IN ZERO DECOMPOSITIONS OF PARTIAL DIFFERENTIAL SYSTEMS显示文摘This paper studies triangular differential systems arising from various decompositions of partial differential polynomial systems. In theoretical aspects, we emphasizeon translating differential problems into purely algebraic ones. Rosenfeld’s lemma is extended to a more general setting; relations between passivity and coherence are clarified;regular systems and simple systems are generalized and proposed, respectively. In algorithmic aspects, we review the Ritt-Wu and Seidenberg algorithms, and outline a methodfor decomposing a differential polynomial system into simple ones. Some applications arealso discussed. | LI Ziming(Institute Of Algorithms and Scientific Computing, German National Research Centerfor Information Technology, D-52754 Sankt Augustin, Germany)WANG Dongming(LEIBNIZ-IMAG, 46, Avenue Felix Viallet,38031 Grenoble Cedex, France) | 1999 | Systems Science and Mathematical Sciences1999,12,S1: | 7 |
| 7 | Characterization of Five Kinds of Wood Vinegar Obtained from Agricultural and Forestry Wastes and Identification of Major Antioxidants in Wood Vinegar显示文摘Wood vinegar(WV)has a powerful antioxidant activity,but it is unclear which components are responsible for the antioxidant activity.In the present study,the double-column retention index qualitative method was used for the identification of the major components in five kinds of W7 And the major antioxidants of wood vinegar were accurately identified with the aid of Pearson product-moment correlation coefficients and authentic standard samples. Our results demonstrate that phenolic compounds are mainly responsible for the powerful antioxidant activity. 2,6-Dimethoxyphenol is the most powerful antioxidant in WV.2-Methoxyphenol and 3-methyl-1,2-cyclopentanedioue also have an important influence on the antioxidant activity of WV.Our results suggest that the contents of 2-methoxyphenol,2,6-dimethoxyphenol and 3-methyl-1,2-cyclopentanedione should act as the criteria for evaluating the antioxidant activity of WV.Our work will provide useful information for WV's application in the fields of food and medicine as antioxidants. | LI Zhanchao ZHANG Zhiquan WU Lijie ZHANG Hanqi WANG Ziming | 2019 | Chemical Research in Chinese Universities2019,35,1: | 4 |
| 8 | Short fixation with a 3‐rod technique for posterior hemivertebra resection in children younger than 5 years old显示文摘Importance Congenital hemivertebra is commonly treated with posterior hemivertebra resection with bilateral transpedicular fixation.However,implant‐related complications are common in children younger than 5 years old who undergo this surgical procedure.Objective To present the preliminary clinical and radiological outcomes of children younger than 5 years old treated by posterior hemivertebra resection and 3‐rod fixation technique.Methods From January 2016 to December 2017,14 consecutive patients of congenital scoliosis with 16 hemivertebrae were retrospectively reviewed,including 5 girls and 9 boys,aged between 25 and 55 months old(average,37.6 months).All patients underwent posterior hemivertebra resection with short fixation with bilateral pedicle screws and a convex lamina hook.Surgical complications and corrective outcomes were assessed based on the clinical charts and spinal radiographs with a minimum 24‐month follow‐up.Results The mean Cobb angle of the main curve was 38.4°before surgery,8.5°after surgery,and 8.7°at final follow‐up.In the compensatory cranial curve,the preoperative Cobb angle of 16.8°was corrected to 8.1°postoperatively and was 10.3°at final follow‐up.In the compensatory caudal curve,the preoperative Cobb angle of 15.9°improved to 5.3°postoperatively and was 7.8°at final follow‐up.The segmental kyphosis was corrected from 13.5°to 0.5°and was 1.1°at final follow‐up.There were no crankshaft phenomena,no proximal kyphosis,and no complications related to the instrumentation.Interpretation Posterior hemivertebra resection with instrumentation with bilateral pedicle screws and a convex lamina hook can achieve rigid fixation and deformity correction. | Dong Guo Ziming Yao Xinyu Qi Chengxin Li Xuejun Zhang | 2020 | Pediatric Investigation2020,4,2: | 4 |
| 9 | Optical properties and cooling performance analyses of single-layer radiative cooling coating with mixture of TiO_(2) particles and SiO_(2) particles显示文摘Radiative cooling can achieve cooling effect without consuming any energy by delivering energy into outer space(3K) through'atmospheric window'(8–13 μm). Conventional radiative cooling coating with multi-layer structure was severely restricted during application due to its complex preparation process and high cost. In this study, a single-layer radiative cooling coating with mixture of TiO_(2) particles and SiO_(2) particles was proposed. The algorithm for calculating the radiative properties of the multi-particle system was developed. Monte Carlo ray-tracing method combined with that algorithm was used to solve the radiative transfer equation(RTE) of the single-layer radiative cooling coating with mixture of TiO_(2) particles and SiO_(2) particles.The effects of particle diameter, volume fraction and coating thickness on radiative cooling performance were analyzed to obtain the best radiative cooling performance. The numerical results indicated that the average reflectivity of the single-layer radiative cooling coating with mixture of TiO_(2) particles and SiO_(2) particles in the solar spectrum can reach 95.6%, while and the average emissivity in the 'atmospheric window' spectrum can reach 94.9% without additional silver-reflectance layer. The average reflectivity in the solar spectrum and average emissivity in the 'atmospheric window' spectrum of the single-layer radiative cooling coating with mixture of TiO_(2) particles and SiO_(2) particles can increase 4.6% and 4.8% compared to the double-layer radiative cooling coating. This numerical research results can provide a theoretical guidance for design and optimization of single-layer radiative cooling coatings containing mixed nanoparticles. | CHENG ZiMing SHUAI Yong GONG DaYang WANG FuQiang LIANG HuaXu LI GuiQiang | 2021 | Science China(Technological Sciences)2021,64,5: | 4 |
| 10 | Oscillation of Surface PM2.5 Concentration Resulting from an Alternation of Easterly and Southerly Winds in Beijing: Mechanisms and Implications显示文摘We used simultaneous measurements of surface PM_(2.5) concentration and vertical profiles of aerosol concentration,temperature, and humidity, together with regional air quality model simulations, to study an episode of aerosol pollution in Beijing from 15 to 19 November 2016. The potential effects of easterly and southerly winds on the surface concentrations and vertical profiles of the PM_(2.5) pollution were investigated. Favorable easterly winds produced strong upward motion and were able to transport the PM_(2.5) pollution at the surface to the upper levels of the atmosphere. The amount of surface PM_(2.5) pollution transported by the easterly winds was determined by the strength and height of the upward motion produced by the easterly winds and the initial height of the upward wind. A greater amount of PM_(2.5) pollution was transported to upper levels of the atmosphere by upward winds with a lower initial height. The pollutants were diluted by easterly winds from clean ocean air masses. The inversion layer was destroyed by the easterly winds and the surface pollutants and warm air masses were then lifted to the upper levels of the atmosphere, where they re-established a multi-layer inversion. This region of inversion was strengthened by the southerly winds, increasing the severity of pollution. A vortex was produced by southerly winds that led to the convergence of air along the Taihang Mountains. Pollutants were transported from southern–central Hebei Province to Beijing in the boundary layer. Warm advection associated with the southerly winds intensified the inversion produced by the easterly winds and a more stable boundary layer was formed. The layer with high PM_(2.5) concentration became dee-per with persistent southerly winds of a certain depth. The polluted air masses then rose over the northern Taihang Mountains to the northern mountainous regions of Hebei Province. | Zhaobin SUN Xiaoling ZHANG Xiujuan ZHAO Xiangao XIA Shiguang MIAO Ziming LI Zhigang CHENG Wei WEN Yixi TANG | 2018 | Journal of Meteorological Research2018,32,2: | 3 |
| 11 | Progress of Jinping Underground laboratory for Nuclear Astrophysics(JUNA)显示文摘Jinping Underground laboratory for Nuclear Astrophysics(JUNA) will take the advantage of the ultra-low background of CJPL lab and high current accelerator based on an ECR source and a highly sensitive detector to directly study for the first time a number of crucial reactions occurring at their relevant stellar energies during the evolution of hydrostatic stars. In its first phase, JUNA aims at the direct measurements of^(25)Mg(p,γ)^(26)Al,^(19)F(p,α)^(16)O,^(13)C(α,n)^(16)O and ^(12)C(α,γ)^(16)O reactions. The experimental setup,which includes an accelerator system with high stability and high intensity, a detector system, and a shielding material with low background, will be established during the above research. The current progress of JUNA will be given. | WeiPing Liu ZhiHong Li JiangJun He XiaoDong Tang Gang Lian Zhu An JianJun Chang Han Chen QingHao Chen XiongJun Chen ZhiJun Chen BaoQun Cui XianChao Du ChangBo Fu Lin Gan Bing Guo GuoZhu He Alexander Heger SuQing Hou HanXiong Huang Ning Huang BaoLu Jia LiYang Jiang Shigeru Kubono JianMin Li KuoAng Li Tao Li YunJu Li Maria Lugaro XiaoBing Luo HongYi Ma ShaoBo Ma DongMing Mei YongZhong Qian JiuChang Qin Jie Ren YangPing Shen Jun Su LiangTing Sun WanPeng Tan Isao Tanihata Shuo Wang Peng Wang YouBao Wang Qi Wu ShiWei Xu ShengQuan Yan LiTao Yang Yao Yang XiangQing Yu Qian Yue Sheng Zeng HuanYu Zhang Hui Zhang LiYong Zhang NingTao Zhang QiWei Zhang Tao Zhang XiaoPeng Zhang XueZhen Zhang ZiMing Zhang Wei Zhao Zuo Zhao Chao Zhou | 2016 | Science China(Physics,Mechanics & Astronomy)2016,59,4: | 3 |
| 12 | Perspectives and challenges for lead-free energy-storage multilayer ceramic capacitors显示文摘The growing demand for high-power-density electric and electronic systems has encouraged the development of energy-storage capacitors with attributes such as high energy density,high capacitance density,high voltage and frequency,low weight,high-temperature operability,and environmental friendliness.Compared with their electrolytic and film counterparts,energy-storage multilayer ceramic capacitors(MLCCs)stand out for their extremely low equivalent series resistance and equivalent series inductance,high current handling capability,and high-temperature stability.These characteristics are important for applications including fast-switching third-generation wide-bandgap semiconductors in electric vehicles,5G base stations,clean energy generation,and smart grids.There have been numerous reports on state-of-the-art MLCC energy-storage solutions.However,lead-free capacitors generally have a low-energy density,and high-energy density capacitors frequently contain lead,which is a key issue that hinders their broad application.In this review,we present perspectives and challenges for lead-free energy-storage MLCCs.Initially,the energy-storage mechanism and device characterization are introduced;then,dielectric ceramics for energy-storage applications with aspects of composition and structural optimization are summarized.Progress on state-of-the-art energy-storage MLCCs is discussed after elaboration of the fabrication process and structural design of the electrode.Emerging applications of energy-storage MLCCs are then discussed in terms of advanced pulsed power sources and high-density power converters from a theoretical and technological point of view.Finally,the challenges and future prospects for industrialization of lab-scale lead-free energy-storage MLCCs are discussed. | Peiyao ZHAO Ziming CAI Longwen WU Chaoqiong ZHU Longtu LI Xiaohui WANG | 2021 | Journal of Advanced Ceramics2021,10,6: | 3 |
| 13 | Optical emission spectroscopy diagnosis of energetic Ar ions in synthesis of SiC polytypes by DC arc discharge plasma显示文摘硅碳化物是有合适的 bandgaps (2.4-3.3 eV ) 和唯一的光性质的尺侧皮的陶艺。有不同形态学,尺寸,和水晶类型的 SiC@C monocrystal nanocapsules 经由快、灵巧的直接水流(DC ) 被综合弧分泌物血浆方法。nanocrystal 的形成上的 Ar 空气的影响原文如此, polytypes 被光排放光谱学(OES ) 调查在弧分泌物血浆上诊断。Boltzmanns 阴谋被用来估计作为 10,582 K 包含不同 Ar 集中的血浆的温度(在 2 ??唓 吗?? | Jian Gao Lei Zhou Jingshuang Liang Ziming wang Yue Wu Javid Muhammad Xinglong Dong Shouzhe Li Hongtao yu Xie Quan | 2018 | Nano Research2018,11,3: | 3 |
| 14 | Multi-scenario Simulation for 2060 and Driving Factors of the Eco-spatial Carbon Sink in the Beibu Gulf Urban Agglomeration, China显示文摘Since China announced its goal of becoming carbon-neutral by 2060, carbon neutrality has become a major target in the development of China's urban agglomerations. This study applied the Future Land Use Simulation(FLUS) model to predict the land use pattern of the ecological space of the Beibu Gulf urban agglomeration, in 2060 under ecological priority, agricultural priority and urbanized priority scenarios. The Integrated Valuation of Ecosystem Services and Trade-offs(In VEST) model was employed to analyse the spatial changes in ecological space carbon storage in each scenario from 2020 to 2060. Then, this study used a Geographically Weighted Regression(GWR) model to determine the main driving factors that influence the changes in land carbon sinking capacity. The results of the study can be summarised as follows: firstly, the agricultural and ecological priority scenarios will achieve balanced urban expansion and environmental protection of resources in an ecological space. The urbanized priority scenario will reduce the carbon sinking capacity. Among the simulation scenarios for 2060, carbon storage in the urbanized priority scenario will decrease by 112.26 × 10^(6) t compared with that for 2020 and the average carbon density will decrease by 0.96 kg/m^(2) compared with that for 2020. Carbon storage in the agricultural priority scenario will increase by 84.11 × 10^(6) t, and the average carbon density will decrease by 0.72 kg/m^(2). Carbon storage in the ecological priority scenario will increase by 3.03 × 10^(6) t, and the average carbon density will increase by 0.03 kg/m^(2). Under the premise that the population of the town will increases continuously, the ecological priority development approach may be a wise choice.Secondly, slope, distance to river and elevation are the most important factors that influence the carbon sink pattern of the ecological space in the Beibu Gulf urban agglomeration, followed by GDP, population density, slope direction and distance to traffic infrastructure.At the same time, urban space expansion is the main cause of the changes of this natural factors. Thirdly, the decreasing trend of ecological space is difficult to reverse, so reasonable land use policy to curb the spatial expansion of cities need to be made. | QIN Menglin ZHAO Yincheng LIU Yuting JIANG Hongbo LI Hang ZHU Ziming | 2023 | Chinese Geographical Science2023,33,1: | 3 |
| 15 | Three-dimensional silk fibroin scaffolds enhance the bone formation and angiogenic differentiation of human amniotic mesenchymal stem cells:a biocompatibility analysis显示文摘Silk fibroin(SF)is a fibrous protein with unique mechanical properties,adjustable biodegradation,and the potential to drive differentiation of mesenchymal stem cells(MSCs)along the osteogenic lineage,making SF a promising scaffold material for bone tissue engineering.In this study,hAMSCs were isolated by enzyme digestion and identified by multiple-lineage differentiation.SF scaffold was fabricated by freeze-drying,and the adhesion and proliferation abilities of hAMSCs on scaffolds were determined.Osteoblast differentiation and angiogenesis of hAMSCs on scaffolds were further evaluated,and histological staining of calvarial defects was performed to examine the cocultured scaffolds.We found that hAMSCs expressed the basic surface markers of MSCs.Collagen type I(COLI)expression was observed on scaffolds cocultured with hAMSCs.The scaffolds potentiated the proliferation of hAMSCs and increased the expression of COL-I in hAMSCs.The scaffolds also enhanced the alkaline phosphatase activity and bone mineralization,and upregulated the expressions of osteogeniorelated factors in vitro.The scaffolds also enhanced the an gioge nic differe ntiati on of hAMSCs.The cocultured scaffolds in creased bone formati on in treating critical calvarial defects in mice.This study first demonstrated that the application of 3D SF scaffolds co-cultured with hAMSCs greatly enhaneed osteogenic differentiation and angiogenesis of hAMSCs in vitro and in vivo.Thus,3D SF scaffolds cocultured with hAMSCs may be a better alter native for bone tissue engin eering. | Yuwan Li Ziming Liu Yaping Tang Qinghong Fan Wei Feng Changqi Luo Guangming Dai Zhen Ge Jun Zhang Gang Zou Yi Liu Ning Hu Wei Huang | 2020 | Acta Biochimica et Biophysica Sinica2020,52,6: | 2 |
| 16 | Development of optical-thermal coupled model for phosphor-converted LEDs显示文摘In this review, first, we discussed the effect of phosphor features on optical properties by the software simulation in detail. A combination of these parameters: phosphor material, phosphor particle size and particle distribution, phosphor layer concentration, phosphor layer thickness, geometry, and location of the phosphor layer, will result in the final optical performance of the phosphor layer. Secondly, we introduced how to improve light extraction efficiency with various proposed methods. Thirdly, we summarized the thermal models to predict the phosphor temperature and the junction temperature. To stabilize the optical performance of phosphor-converted light emitting diodes (PC-LEDs), much effort has been made to reduce the junction temperature of the LED chips. The phosphor temperature, a critical reliability concern for PC-LEDs, should be attracted academic interest. Finally, we summed up optical-thermal coupled model for phosphors and summarized future optical- thermal issues exploring the light quality for LEDs. We foresee that optical-thermal coupled model for PC-LEDs should be paid more attention in the future. | Xinglu QIAN Jun ZOU Mingming SHI Bobo YANG Yang LI Ziming WANG Yiming LIU Zizhuan LIU Fei ZHENG | 2019 | Frontiers of Optoelectronics2019,12,3: | 2 |
| 17 | In situ construction of ligand nano-network to integrin αvβ3 for angiogenesis inhibition显示文摘Angiogenesis occurs during the process of tumor growth,invasion and metastasis,and is essential for the survival of solid tumors.As an integrin significantly ove rexpressed in human tumor vascular endothelial cells,αvβ3 is a suitable targeting site for anti-angiogenesis of tumor.We designed and prepared a selfassembling peptide(SAP)with the ability to targeting αvβ3 and self-assembly.SAP formed nanoparticles in solution and transformed into nanofibrous network once specifically binding to integrin αvβ3 on the surface of human umbilical vein endothelial cells(HUVECs).The SAP network stably anchored on HUVECs over 24h,which consequently resulted in high-efficient inhibition of vascularization.In vitro anti-angiogenesis experiment displayed that the inhibition rate of tube-formation reached 94.9%.In vivo anti-angiogenesis array based on chick chorioallantoic membrane(CAM)model exhibited that the SAP had an inhibition rate up to 63.1%.These results indicated the outstanding anti-angiogenic ability of SAP,potentially for tumor therapy. | Ziming Chen Kuo Zhang Jiaqi Fan Yu Fan Chao Yang Wen Tian Yuan Li Wenliang Li Jingping Zhang Hao Wang Lei Wang | 2020 | Chinese Chemical Letters2020,31,12: | 2 |
| 18 | Synthesis, characterization and performance of a polycarboxylate superplasticizer with amide structure显示文摘 | Xiao Liu Ziming Wang Jie Zhu Yunsheng Zheng Suping Cui Mingzhang Lan Huiqun Li | 2014 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2014,,: | 2 |
| 19 | Effect of mowing on N2O and CH4 fluxes emissions from the meadow-steppe grasslands of Inner Mongolia显示文摘估计在 N 2 从内部蒙古的草地大草原草地的 O 和 CH 4 流动排出物,中国,二政体被调查:unmown 自从 2005 (嗯) ,并且 mow 的过去分词一次每三年自从 2009 (M3 ) 。所在地的大小在一个整年的时期(到 2012 年 8 月的 2011 年 8 月) 期间连续地被进行。在观察时期期间,三日报周期也被测量。另外,一个指向的实验室实验被进行在冬季补救很少大小。N 2 与结冰融化周期有关的 O 排出物在春天解冻期间在 M3 被观察。结果证明草地大草原为 N 24 和来源作为一个水池起了一个作用 > O。显著地更低的吝啬的 CH 4举起在嗯( 40.3 g C 獡攠慶畬瑡摥?潇摯氠湩慥楲祴??猼灵资???????漠?桴?慣楬牢瑡潩?畣癲獥映牯焠慵瑮晩捩瑡潩?慷?扯慴湩摥漠敶?桴?祤慮業?慲杮?景????朿洿????猯灵?愠摮瀠牥散瑮爠汥瑡癩?瑳湡慤摲搠癥慩楴湯眠獡ㄠ????慥档湩?硥数楲敭瑮猠潨敷?桴瑡挠慹潺慦業?潣汵?潮?敬捡敨?敢潹摮ㄠ?浣漠?潳汩搠灥桴?慍楸畭?潣据湥牴瑡潩?慷?瑡??愠摮ㄠ??浣猠楯?敤瑰??敶慲敧爠'恬碃皵?牦浯猠楯獬映牯楴楦摥愠???? 鄿靗鵌 ? | Zedong LU Rui DU Pengrui DU Ziming LI Zongmin LIANG Yaling WANG Saisai QIN LeiZHONG | 2015 | Frontiers of Earth Science2015,9,3: | 2 |
| 20 | A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury显示文摘Spinal cord injury(SCI)is an overwhelming and incurable disabling event accompanied by complicated inflammation-related pathological processes,such as excessive reactive oxygen species(ROS)produced by the infiltrated inflammatory immune cells and released to the extracellular microenvironment,leading to the widespread apoptosis of the neuron cells,glial and oligodendroctyes.In this study,a thioketal-containing and ROS-scavenging hydrogel was prepared for encapsulation of the bone marrow derived mesenchymal stem cells(BMSCs),which promoted the neurogenesis and axon regeneration by scavenging the overproduced ROS and re-building a regenerative microenvironment.The hydrogel could effectively encapsulate BMSCs,and played a remarkable neuroprotective role in vivo by reducing the production of endogenous ROS,attenuating ROS-mediated oxidative damage and downregulating the inflammatory cytokines such as interleukin-1 beta(IL-1β),interleukin-6(IL-6)and tumor necrosis factor-alpha(TNF-α),resulting in a reduced cell apoptosis in the spinal cord tissue.The BMSCs-encapsulated ROS-scavenging hydrogel also reduced the scar formation,and improved the neurogenesis of the spinal cord tissue,and thus distinctly enhanced the motor functional recovery of SCI rats.Our work provides a combinational strategy against ROS-mediated oxidative stress,with potential applications not only in SCI,but also in other central nervous system diseases with similar pathological conditions. | Ziming Li Tengfei Zhao Jie Ding Haochen Gu Qiaoxuan Wang Yifan Wang Deteng Zhang Changyou Gao | 2023 | Bioactive Materials2023,,1: | 2 |