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| 1 | Homology-mediated end joining-based targeted integration using CRISPR/Cas9显示文摘 | Yao, Xuan Wang, Xing Hu, Xinde Liu, Zhen Liu, Junlai Zhou, Haibo Shen, Xiaowen Wei, Yu Huang, Zijian Ying, Wenqin Wang, Yan Nie, Yan-Hong Zhang, Chen-Chen Li, Sanlan Cheng, Leping Wang, Qifang Wu, Yan Huang, Pengyu Sun, Qiang Shi, Linyu Yang, Hui | 2017 | Cell Research2017，27，6： | 28 |
| 2 | Environmental change since mid-Pleistocene recorded in Shangshan achaeological site of Zhejiang显示文摘在迟了的时期的大约 173 ka BP 中间 -- 更新世,河的第二个平台被形成了由于因为气候,海水平变化和构造行动,高举发生在 Shangshan 区域。在 173 75 ka BP 之间。 | MAO Longjiang MO Duowen JIANG Leping JIA Yaofeng LIU Xiaoyan LI Minglin ZHOU Kunshu SHI Chenxi | 2008 | Journal of Geographical Sciences2008，18，2： | 6 |
| 3 | Spatiotemporal alterations of presynaptic elements in the retina after high intraocular pressure显示文摘A rat model of acute high intraocular pressure was established by injecting saline into the anterior chamber of the left eye.Synaptophysin expression was increased in the inner plexiform layer at 2 hours following injury,and was widely distributed in the outer plexiform layer at 3-7 days,and then decreased to the normal level at 14 days.This suggests that expression of this presynaptic functional protein experienced spatiotemporal alterations after elevation of intraocular pressure.There was no significant change in the fluorescence intensity and distribution pattern for synapse-associated protein 102 following elevated intraocular pressure.Synapse-associated protein 102 immunoreactivity was confined to the outer plexiform layer,while synaptophysin immunoreactivity spread into the outer plexiform layer and the outer nuclear layer at 3 and 7 days following injury.These alterations in presynaptic elements were not accompanied by changes in postsynaptic components. | Jufang Huang Lihong Zhou Hui Wang Jia Luo Kun Xiong Leping Zeng Dan Chen | 2012 | Neural Regeneration Research2012，7，16： | 2 |
| 4 | Regulatory effects of inhibiting the activation of glial cells on retinal synaptic plasticity显示文摘Various retinal injuries induced by ocular hypertension have been shown to induce plastic changes in retinal synapses,but the potential regulatory mechanism of synaptic plasticity after retinal injury was still unclear.A rat model of acute ocular hypertension was established by injecting saline intravitreally for an hour,and elevating the intraocular pressure to 14.63 kPa(110 mmHg).Western blot assay and immunofluorescence results showed that synaptophysin expression had a distinct spatiotemporal change that increased in the inner plexiform layer within 1 day and spread across the outer plexiform layer after 3 days.Glial fibrillary acidic protein expression in retinae was greatly increased after 3 days,and reached a peak at 7 days,which was also consistent with the peak time of synaptophysin expression in the outer plexiform layer following the increased intraocular pressure.Fluorocitrate,a glial metabolic inhibitor,was intravitreally injected to inhibit glial cell activation following high intraocular pressure.This significantly inhibited the enhanced glial fibrillary acidic protein expression induced by high intraocular pressure injury.Synaptophysin expression also decreased in the inner plexiform layer within a day and the widened distribution in the outer plexiform layer had disappeared by 3 days.The results suggested that retinal glial cell activation might play an important role in the process of retinal synaptic plasticity induced by acute high intraocular pressure through affecting the expression and distribution of synaptic functional proteins,such as synaptophysin. | Lihong Zhou Hui Wang Jia Luo Kun Xiong Leping Zeng Dan Chen Jufang Huang | 2014 | Neural Regeneration Research2014，9，4： | 2 |
| 5 | On new extensions of Hilbert's integral inequality显示文摘 | He Leping Gao Mingzhe Zhou Yu | 2008 | International Journal of Mathematics and Mathematical Science2008，，： | 1 |
| 6 | An effective method of DNA extraction for bioleaching bacteria from acid mine drainage显示文摘 | Leping Zeng Jufang Huang Yanfei Zhang Guanzhou Qiu Jianbin Tong Dan Chen Jin Zhou Xuegang Luo | 2008 | Applied Microbiology and Biotechnology2008，，5： | 1 |
| 7 | The damage assessment of marine oil spill pollution using Back-Propagation neu- ral network显示文摘 | Zhou Junfeng Xu Leping | 2011 | Energy Procedia2011，11，： | 1 |
| 8 | A fractal model for predicting the effective thermalconductivity of liquid with suspension of nanoparticles显示文摘 | Wang Buxuan Zhou Leping Peng Xiaofeng | 2003 | Int J Heat and Mass Transfer2003，46，： | 1 |
| 9 | Bubble circling phenomena in subcooled nucleate pool boiling on microwires显示文摘 | Leping Zhou Longting Wei Yuanyuan Li Xiaoze Du Buxuan Wang | 2013 | International Journal of Heat and Mass Transfer2013，，： | 1 |
| 10 | A fractal model for predicting the effective thermal conductivity of liquid with suspension of nanoparticles 显示文摘 | Wang Buxuan Zhou Leping Peng Xiaofeng | 2003 | International Journal of Heat and Mass Transfer2003，46，14： | 1 |
| 11 | A Prac- tal Model for Predicting the Effective Thermal Conduc- tivity of Liquid With Suspension of Nanoparticles 显示文摘 | WANG Buxuan ZHOU Leping PENG Xiaofeng | 2003 | In- ternationM Journal of Heat and Mass Transfer2003，46，： | 1 |
| 12 | Ti2AlC triggered in-situ ultrafine TiC/Inconel 718 composites:Microstructure and enhanced properties显示文摘In situ ultrafine TiC dispersion reinforced Inconel 718 alloy with enhanced mechanical properties was fabricated by the technique of reactive hot-press sintering Ti2AlC and In718 powders.The effect of Ti2AlC precursor additions(5 vol.%,10 vol.%,15 vol.%)on microstructure and mechanical properties of TiC/In718 composites were investigated.A relationship of microstructural characteristics,room and elevated temperature mechanical performance,and underlying strengthening mechanisms were analyzed.The results show that initial Ti2AlC precursor transformed completely into ultrafine TiC particulate(~230 nm)and distributed uniformly in the matrix after sintering 5 and 10 vol.%Ti2AlC/In718.However,TiC particulates tended to aggregate to stripes with the addition of Ti2AlC up to 15 vol.%,which,in adverse,weaken the properties of In718.The 5 vol.%Ti2AlC/In718 sample showed a higher tensile strength of 1404±13 MPa with a noticeable elongation of 9.8%at room temperature compared to the pure In718(ultimate tensile strength(UTS)=1310 MPa,elongation=21.5%).At 600℃,700℃,800℃and 900℃,tensile strength of the as-sintered 5 vol.%Ti2AlC/In718 composite was determined to be 1333±13 MPa,1010±10 MPa,685±25 MPa and 276±3 MPa,increased by 9.2%,14.6%,14.2%and 55%,respectively,compared with that of monolithic In718 alloy.The excellent tensile properties of TiC/In718 composite can be ascribed to the combined mechanisms in term of increased dislocation density,dispersive Orowan and load transfer mechanisms. | Wenqiang Hu Zhenying Huang Qun Yu Yuanbo Wang Yidan Jiao Cong Lei Leping Cai Hongxiang Zhai Yang Zhou | 2020 | Journal of Materials Science & Technology2020，47，16： | 1 |
| 13 | Uncertainty Analysis in CFD for Resistance显示文摘基于数字在 CFD (计算液体动力学) 作为无常的三个主要因素被拿的统计,第一边界层的厚度,骚乱模型和房间的拉丁方形的设计。壳的全部的抵抗被计算,在壳附近的流动地被 CFD 方法模仿。然后,壳抵抗上的无常因素的影响被回归分析与整修网孔讨论并且搅乱网孔。通过一系列计算和分析,最佳的计算方法被提出,并且计算的相关参数是坚定的。第三,不同速度的全部的抵抗被使用这些二种格子计算,它在对试验性的结果的好同意。最后,根据 ITTC 推荐了过程,在 CFD 的无常分析被格子的三个集合与一致精炼比率 rG = 与全部的抵抗的数字结果执行 2。当时,修改抵抗与试验性的结果相比,它改进了抵抗预言的精确性。 | WANG Zhongcheng LIU Xiaoyu ZHANG Shenglong XU Leping ZHOU Peilin | 2017 | Journal of Shipping and Ocean Engineering2017，7，5： | 0 |
| 14 | Microstructure and Hot Deformation Behavior of Mg-9Al-3Si-0.375Sr-0.78Y Alloy显示文摘Using Gleeble-3500 thermal simulator,the high temperature plastic deformation behavior and microstructure evolution of Mg-9Al-3Si-0.375Sr-0.78Y alloy are investigated at the temperature of 523 K?673 K and the strain rate of 10^(-3)s^(-1) 10 s^(-1).True strain-true stress curves show the characteristics of the typical dynamically recrystallization process.The Arrhenius constitutive equation of the hyperbolic model is established.The average activation energy and the strain rate sensitivity index are,respectively,221.578 kJ·mol^(-1) and 0.137.The result shows that theα-Mg phase exhibits dynamic recrystallization (DRX)characteristics obviously.But no DRX occurs in the β-Mg_(17)Al_(12) phase.Hot deformation does not affect the primary Mg_(2)Si phase.Under the conditions of low temperature (523 K?673 K) and high strain rate(1 s^(-1) 10 s^(-1)),the flow instability and macro-defects such as crack appear in the specimens.However,there are finer recrystallization grains.Under the conditions of high temperature(≥673 K)or low strain rate,the microstructure of the alloy shows good homogeneity.The size of the primary Mg_(2)Si phase is uniform,the size of the β-Mg_(17)Al_(12) phase is small,and the distribution of the β-Mg_(17)Al_(12) phase is uniform. | CHEN Leping ZHANG Lianteng XU Yong ZHOU Quan | 2022 | 上海航天(中英文)2022，39，1： | 0 |
| 15 | Games theory and the development of research paper publishing显示文摘 | ZHOU Leping | 2018 | International English Education Research2018，，4： | 0 |
| 16 | Oxidized Dopamine Acrylamide Primer to Achieve Durable Resin-Dentin Bonding显示文摘The durability of the resin-dentin bonding interface is a key issue in clinical esthetic dentistry.Inspired by the extraordinary bioadhesive properties of marine mussels in a wet environment,we designed and synthetized N-2-(3,4-dihydroxylphenyl)acrylamide(DAA)according to the functional domain of mussel adhesive proteins.DAA’s properties of collagen cross-linking,collagenase inhibition,inducing collagen mineralization in vitro,and as a novel prime monomer for clinical dentin adhesion use,its optimal parameters,and effect on the adhesive longevity and the bonding interface’s integrity and mineralization,were evaluated in vitro and in vivo.The results showed that oxide DAA can inhibit the activity of collagenase and cross collagen fibers to improve the anti-enzymatic hydrolysis of collagen fibers and induce intrafibrillar and interfibrillar collagen mineralization.As a primer used in the etch-rinse tooth adhesive system,oxide DAA can improve the durability and integrity of the bonding interface by anti-degradation and mineralization of the exposed collagen matrix.Oxidized DAA(OX-DAA)is a promising primer for improving dentin durability;using 5%OX-DAA ethanol solution and treating the etched dentin surface for 30 s is the optimal choice when used as a primer in the etch-rinse tooth adhesive system. | Leping Wu Hui Shao Yang Tao Jingya Wu Xinhui Wang Qiufeng Nian Shunli Zheng Chris Ying Cao Yuancong Zhao Zheng Zhou Hai Ming Wong Quan-Li Li | 2023 | Research2023，，4： | 0 |
| 17 | A Molecular Analysis of Critical Factors for Interface and Size Effects on Heat Conduction in Nanoconfined Water Film显示文摘Heat conduction of nanoconfined liquid may differ from its bulk because of the effects of size,geometry,interface,temperature,etc.In this study,the roles of some critical factors for the heat conduction of nanoconfined water film are systematically analyzed by using the molecular dynamics method.With decreasing thickness,the normal thermal conductivity of nanoconfined water film between two copper plates decreases exponentially,while the thermal resistance,peak of the radial distribution function,and atomistic heat path increase exponentially.The average bond order,radial distribution function,mean squared displacement,and vibrational density of states are calculated to analyze the effects of structure,distribution,molecular diffusion,and vibration of water molecules on heat conduction especially in a region having no oxygen atoms(which is observed by the near-wall density profile).The results show that phonon scattering is dominant for determining the reduced thermal conductivity in this near-wall region.The thermal conductivity ratio of confined water film to bulk water has a roughly linear relationship with the logarithm of the proportion of the near-wall region.Moreover,the high interfacial thermal resistance is positively correlated to the film thickness,but it has a negligible impact on heat conduction.This work provides insights into the contribution of water molecules near the solid/liquid interface to the heat conduction of nanoconfined liquid for process intensification. | JIN Lu ZHOU Leping DU Xiaoze | 2022 | Journal of Thermal Science2022，31，4： | 0 |
| 18 | Comparison analysis of sampling methods to estimate regional precipitation based on the Kriging interpolation methods: A case of northwestern China显示文摘The accuracy of spatial interpolation of precipitation data is determined by the actual spatial variability of the precipitation, the interpolation method, and the distribution of observatories whose selections are particularly important. In this paper, three spatial sampling programs, including spatial random sampling, spatial stratified sampling, and spatial sandwich sampling, are used to analyze the data from meteorological stations of northwestern China. We compared the accuracy of ordinary Kriging interpolation methods on the basis of the sampling results. The error values of the regional annual precipitation interpolation based on spatial sandwich sampling, including ME(0.1513), RMSE(95.91), ASE(101.84), MSE(-0.0036), and RMSSE(1.0397), were optimal under the premise of abundant prior knowledge. The result of spatial stratified sampling was poor, and spatial random sampling was even worse. Spatial sandwich sampling was the best sampling method, which minimized the error of regional precipitation estimation. It had a higher degree of accuracy compared with the other two methods and a wider scope of application. | JinKui Wu ShiWei Liu LePing Ma Jia Qin JiaXin Zhou Hong Wei | 2016 | Research in Cold and Arid Regions2016，8，6： | 0 |
| 19 | Combining forms of heavy metal elements in Dianshan Lake sediments and their spatial and temporal variations显示文摘 | Leping ZHENG Yuliang LIU Xiaoyan SHI Xianwen QIAN Lihua ZHOU Xiaoyan LIU Xinxin WU Weimin SUN | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 0 |
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