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| 1 | Nuclear Aurora kinase A switches m^(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4显示文摘Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression,yet how this process is regulated by oncogenic signal remains largely unknown.Here,we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m^(6)A reader YTHDC1 in lung cancer.Nuclear translocation of AURKA is a prerequisite for RNA aberrant splicing,specifically triggering RBM4 splicing from the full isoform(RBM4-FL)to the short isoform(RBM4-S)in a kinase-independent manner. | SiSi Li YangFan Qi JiaChuan Yu YuChao Hao Bin He MengJuan Zhang ZhenWei Dai TongHui Jiang SuYi Li Fang Huang Ning Chen Jing Wang MengYing Yang DaPeng Liang Fan An JinYao Zhao WenJun Fan YuJia Pan ZiQian Deng YuanYuan Luo Tao Guo Fei Peng ZhiJie Hou ChunLi Wang FeiMeng Zheng LingZhi Xu Jie Xu QingPing Wen BiLian Jin Yang Wang Quentin Liu | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 4 |
| 2 | Histone demethylase KDM2B promotes triple negative breast cancer proliferation by suppressing p 15^INK4B, p 16^INK4A, and p57^KIP2 transcription显示文摘 | Qingping Zheng Hongjia Fan Zhenzhen Meng Lin Yuan Cuicui Liu You Peng Weiwei Zhao Lulu Wang Jing Li Jing Feng | 2018 | Acta Biochimica et Biophysica Sinica2018，50，9： | 3 |
| 3 | Integrated Wide Area Protection and Control for Power Grid Security显示文摘The traditional“three defense lines”for power systems are based on local information and static protection&control strategy,which are not suitable to modern large-scale power systems.In order to improve the security of UHV hybrid power grids,the Integrated Wide Area Protection&Control(IWAPC)is proposed in this paper by applying the new technologies of synchronized high-speed communication,which integrates“three defense lines”and promotes existing wide area protection only for security control.The IWAPC is the hierarchical protection and control system which provides the protection and control for wide area power networks to improve their reliability and security.It is divided into three levels,the local bay level,the substation integrated protection level and the wide area protection level.The wide area real-time protection and control information platform is the most important part of the IWAPC,which is based on a synchronized wide area communication network.The key technologies and new development trends include network topology analysis,wide area backup protection,wide area intelligent reclosing,wide area load shedding,wide area auto-switching,overload cutoff and transfer,transmission section protection,intelligent system splitting and dynamic stability control.It cannot only integrate three lines of defense for power system protection and control,but also improve security of the power grid. | Qingping Wang Zhiqian Bo Yingke Zhao Xiaowei Ma Ming Zhang Hao Zheng Lin Wang | 2019 | CSEE Journal of Power and Energy Systems2019，5，2： | 2 |
| 4 | Theory of passive localization for underwater sources based on acoustic ray modeling显示文摘The theory of passive localization for underwater sources based on acoustic ray channel modeling is discussed. The principles of channel modeling in Ray-theory, determination of eigenrays which connect source and receiver, analysis of DOA arriving structure and time delay spectrum arriving structure, their relationship to source location are given in the paper. Source location is estimated by matching measured DOA and TDS to their calculated counterparts. The method of Ray-theory based passive localization features its simplicity, less calculation, short array aperture and robust performance to environment parameters, as compared with those methods based on Normal Mode theory. | SUN Zhenge (National Laboratory of Acoustics Beijing 100080)MA Yuanliang TU Qingping and JIANG Xiaoquan(College of Marine Engineering, NPU Xi’an 710072) | 1997 | Chinese Journal of Acoustics1997，16，3： | 2 |
| 5 | A computational study of combustion in compression ignition natural gas engine with separated chamber显示文摘 | Zheng Qingping Zhang Huiming Zhang Defu | 2005 | Fuel2005，84，1213： | 1 |
| 6 | Creating oxygen vacancies as a novel strategy to form tetrahedrally coordinated Ti^4+ in Fe/TiO2 nanoparticles 显示文摘 | WU Qingping ZHENG Qiang KROL R | 2012 | J Phys Chem C2012，116，12： | 1 |
| 7 | Evidence for the role of KIF17 in fish spermatid reshaping:expression pattern of KIF17 in Larimichthys polyactis spermiogenesis显示文摘The homodimeric kinesin-2 protein KIF17 functions in intracellular transport and spermiogenesis in mammals.However,its role in fish spermiogenesis has not been reported.Here,we aimed to clone full-length kif17 cDNA and determine the molecular characteristics and expression patterns of KIF17 in Larimichthys polyactis spermiogenesis.The full-length cDNA of L.polyactis kif17(Lp-kif17)was sequenced and found to contain a 332-bp 5′untranslated region,480-bp 3′untranslated region,and 2433-bp open reading frame encoding 810 amino acids.Bioinformatics analyses showed that L.polyactis KIF17(Lp-KIF17)shared high sequence similarity with homologs in other animals and possessed an N-terminal motor domain with microtubule-binding sites and adenosine triphosphate(ATP)hydrolysis sites,a stalk domain containing two coiled-coil regions,and a C-terminal tail domain.The Lp-kif17 mRNA was widely expressed in various tissues,with the highest level in the brain,followed by that in the testis.Fluorescence in situ hybridization(FISH)analysis revealed that Lp-kif17 was continuously expressed in spermiogenesis,showing that it had potential functions in this process.Using immunofluorescence(IF)analysis,we found that Lp-KIF17 colocalized with tubulin and was transferred from the perinuclear cytoplasm to the side of spermatid where the tail forms during spermiogenesis.These findings suggested that KIF17 is involved in L.polyactis spermiogenesis.In particular,it may participate in nuclear shaping and tail formation by interacting with perinuclear microtubules during spermatid reshaping.In addition to providing evidence for the role of KIF17 in fish spermatid reshaping,this study provides important data for studies of reproductive biology in L.polyactis. | Jingqian WANG Xinming GAO Xuebin ZHENG Chen DU Congcong HOU Qingping XIE Bao LOU Feng LIU Shan JIN Junquan ZHU | 2021 | Journal of Oceanology and Limnology2021，39，6： | 1 |
| 8 | Using similarity theory to design natural gas hydrate experimental model显示文摘 | ZHENG Ruyi LI Shuxia LI Qingping | 2015 | Journal of Natural Gas Science and Engineering2015，22，： | 1 |
| 9 | A computational study of combustion in compression ignition natural gas engine with separated chamber 显示文摘 | Zheng Qingping Zhang Huiming Zhang Defu | 2005 | Fuel2005，84，1213： | 1 |
| 10 | Novel Ag-bridged dual Z-scheme g-C_(3)N_(4)/BiOI/AgI plasmonic heterojunction: Exceptional photocatalytic activity towards tetracycline and the mechanism insight显示文摘Rational design and synthesis of highly efficient and robust photocatalysts with positive exciton splitting and interfacial charge transfer for environmental applications is critical.Herein,aiming at overcoming the common shortcomings of traditional photocatalysts such as weak photoresponsivity,rapid combination of photo-generated carriers and unstable structure,a novel Ag-bridged dual Z-scheme g-C_(3)N_(4)/BiOI/AgI plasmonic heterojunction was successfully synthesized using a facile method.Results showed that Ag-AgI nanoparticles and three-dimensional(3D)BiOI microspheres were decorated highly uniformly on the 3D porous g-C_(3)N_(4) nanosheet,resulting in a higher specific surface area and abundant active sites.The optimized 3D porous dual Z-scheme g-C_(3)N_(4)/BiOI/Ag-AgI manifested exceptional photocatalytic degradation efficiency of tetracycline(TC)in water with approximately 91.8%degradation efficiency within 165 min,outperforming majority of the reported g-C_(3)N_(4)-based photocatalysts.Moreover,g-C_(3)N_(4)/BiOI/Ag-AgI exhibited good stability in terms of activity and structure.In-depth radical scavenging and electron paramagnetic resonance(EPR)analyses confirmed the relative contributions of various scavengers.Mechanism analysis indicated that the improved photocatalytic performance and stability were ascribed to the highly ordered 3D porous framework,fast electron transfer of dual Z-scheme heterojunction,desirable photocatalytic performance of BiOI/AgI and synergistic effect of Ag plasmas.Therefore,the 3D porous Z-scheme g-C_(3)N_(4)/BiOI/Ag-AgI heterojunction had a good prospect for applications in water remediation.The current work provides new insight and useful guidance for designing novel structural photocatalysts for environment-related applications. | Wenxia Wang Zhen Li Kailin Wu Guodong Dai Qingping Chen Lihua Zhou Junxia Zheng Liang Ma Guiying Li Wanjun Wang Taicheng An | 2023 | Journal of Environmental Sciences2023，，9： | 0 |
| 11 | High-performance supercapacitors based on Ni_(2)P@CNT nanocomposites prepared using an ultrafast microwave approach显示文摘We present a one-step route for the preparation of nickel phosphide/carbon nanotube(Ni_(2)P@CNT)nanocomposites for supercapacitor applications using a facile,ultrafast(90 s)microwave-based approach.Ni2P nanoparticles could grow uniformly on the surface of CNTs under the optimized reaction conditions,namely,a feeding ratio of 30:50:25 for CNT,Ni(NO_(3))_(2)-6H_(2)O,and red phosphorus and a microwave power of 1000 W for 90 s.Our study demonstrated that the single-step microwave synthesis process for creating metal phosphide nanoparticles was faster and simpler than all the other existing methods.Electrochemical results showed that the specific capacitance of the optimal Ni2P@CNT-nanocomposite electrode displayed a high specific capacitance of 854 F•g^(-1) at 1 A•g^(-1) and a superior capacitance retention of 84% after 5000 cycles at 10 Ag^(-1).Finally,an asymmetric supercapacitor was assembled using the nanocomposite with activated carbon as one electrode(Ni_(2)P@CNT//AC),which showed a remarkable energy density of 33.5 W•h•kg^(-1) and a power density of 387.5 W·kg^(-1).This work will pave the way for the microwave synthesis of other transition metal phosphide materials for use in energy storage systems. | Yunrui Tian Haishun Du Shatila Sarwar Wenjie Dong Yayun Zheng Shumin Wang Qingping Guo Jujie Luo Xinyu Zhang | 2021 | Frontiers of Chemical Science and Engineering2021，15，4： | 0 |
| 12 | Thermal Conversion of Semi-insulating GaAs due to Gallium Vacancies and Anti-structure Disorders显示文摘Rapid thermal annealing induced acceptor levels and their annealing behavior in semi-insulating GaAs were investigated using the photoluminescence technique.Results suggest that the introduction of excess of Vg„and Gax»related acceptors might lead to thermal conversion of GaAs wafers. | WENG Yumin ZHENG Qingping FAN Zhineng ZONG Xiangfu | 1992 | Chinese Physics Letters1992，9，7： | 0 |
| 13 | Testis Development and Ultrastructural Features During Spermatogenesis in Cultured Small Yellow Croaker,Larimichthys polyactis显示文摘The small yellow croaker Larimichthys polyactis is an economically important marine fish in Northeast Asia.Currently,its natural resources are threatened by overfishing and environmental pollution.Therefore,research on the reproductive system of the fish is crucial.Here,we studied the testis development and ultrastructural features of spermatogenesis in cultured L.polyactis using anatomical,histological,and ultrastructural techniques.A pair of testes,consisting of a central sperm duct and radial seminiferous lobules,were observed.The reproduction cycle of testes can be divided into stages I–VI.March to May was confirmed as the breeding season for male L.polyactis,while April is the ideal period for artificial breeding.The male L.polyactis can attain sexual maturity within 1 year.The spermatogenesis of L.polyactis comprised spermatogonium,spermatocyte,spermatid,and mature spermatozoon.The morphology of spermatogenic cells changed obviously during spermiogenesis,including nuclear shaping,midpiece and flagellum formation.The mature sperms consist of an ellipsoidal head,a short midpiece,and a long flagellum.The anterior of the head with a kidney-shaped nucleus can be distinguished.The midpiece is located posterior to the head and includes four to six spherical mitochondria.The flagellum has irregular lateral fins.The testis of L.polyactis is an unrestricted lobular type,with cystic spermatogenesis,type II spermiogenesis,and type II spermatozoa.These features are highly similar to those of other Sciaenid species.Our findings provide useful insights into the mechanism underlying testis development and spermatogenesis of L.polyactis,which can facilitate the artificial breeding of this species. | ZHENG Xuebin WANG Jingqian GAO Xinming DU Chen HOU Congcong XIE Qingping LIU Feng ZHU Junquan LOU Bao | 2023 | Journal of Ocean University of China2023，22，5： | 0 |
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