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    题名 作者 年代 出处 被引量
1Glacier area variation and climate change in the Chinese Tianshan Mountains since 1960显示文摘基于自从 1960,在中国 Tianshan 山测量的冰河区域变化的统计,到气候变化的冰河区域变化的反应系统地被讨论。作为结果,冰河的全部的区域被 11.5% 在过去的 50 年里减少了,它根据中国(GIC ) 的冰河库存分开的 10 排水盆的冰河区域变化是一个加权的百分比。在中国 Tianshan 山的冰河的区域变化(APAC ) 的年度百分比在学习时期的标准化以后是 0.31% 。APAC 为不同排水盆广泛地变化,但是冰河通常处于快速的撤退的一个国家。根据在中国 Tianshan 山的 14 个气象学的车站,温度和降水以 0.34 整湲椠 ? 潮 ?湵晩牯 m 的率从 1960 ~ 2009WANG Shengjie ZHANG Mingjun LI Zhongqin WANG Feiteng LI Huilin LI Yaju HUANG Xiaoyan 2011Journal of Geographical Sciences2011,21,2:31
2High matrix metalloproteinase-9 expression induces angiogenesis and basement membrane degradation in stroke-prone spontaneously hypertensive rats after cerebral infarction显示文摘Basement membrane degradation and blood-brain barrier damage appear after cerebral infarction, severely impacting neuronal and brain functioning; however, the underlying pathogenetic mechanisms remain poorly understood. In this study, we induced cerebral infarction in strokeprone spontaneously hypertensive rats by intragastric administration of high-sodium water(1.3% NaCl) for 7 consecutive weeks. Immunohistochemical and immunofluorescence assays demonstrated that, compared with the non-infarcted contralateral hemisphere, stroke-prone spontaneously hypertensive rats on normal sodium intake and Wistar-Kyoto rats, matrix metalloproteinase-9 expression, the number of blood vessels with discontinuous collagen IV expression and microvessel density were significantly higher, and the number of continuous collagen IV-positive blood vessels was lower in the infarct border zones of stroke-prone spontaneously hypertensive rats given high-sodium water. Linear correlation analysis showed matrix metalloproteinase-9 expression was positively correlated with the number of discontinuously collagen IV-labeled blood vessels and microvessel density in cerebral infarcts of stroke-prone spontaneously hypertensive rats. These results suggest that matrix metalloproteinase-9 upregulation is associated with increased regional angiogenesis and degradation of collagen IV, the major component of the basal lamina, in stroke-prone spontaneously hypertensive rats with high-sodium water-induced focal cerebral infarction.Huilian Hou Guanjun Zhang Hongyan Wang Huilin Gong Chunbao Wang Xuebin Zhang 2014Neural Regeneration Research2014,9,11:30
3One-year clinical study of NeuroR egen scaffold implantation following scar resection in complete chronic spinal cord injury patients显示文摘The objective of this clinical study was to assess the safety and feasibility of the collagen scaffold, Neuro Regen scaffold, one year after scar tissue resection and implantation. Scar tissue is a physical and chemical barrier that prevents neural regeneration. However, identification of scar tissue is still a major challenge. In this study, the nerve electrophysiology method was used to distinguish scar tissue from normal neural tissue, and then different lengths of scars ranging from 0.5–4.5 cm were surgically resected in five complete chronic spinal cord injury(SCI) patients. The NeuroR egen scaffold along with autologous bone marrow mononuclear cells(BMMCs), which have been proven to promote neural regeneration and SCI recovery in animal models, were transplanted into the gap in the spinal cord following scar tissue resection. No obvious adverse effects related to scar resection or Neuro Regen scaffold transplantation were observed immediately after surgery or at the 12-month follow-up. In addition, patients showed partially autonomic nervous function improvement, and the recovery of somatosensory evoked potentials(SSEP) from the lower limbs was also detected. The results indicate that scar resection and Neuro Regen scaffold transplantation could be a promising clinical approach to treating SCI.Zhifeng Xiao Fengwu Tang Jiaguang Tang Huilin Yang Yannan Zhao Bing Chen Sufang Han Nuo Wang Xing Li Shixiang Cheng Guang Han Changyu Zhao Xiaoxiong Yang Yumei Chen Qin Shi Shuxun Hou Sai Zhang Jianwu Dai 2016Science China(Life Sciences)2016,59,7:18
4Cigarette Smoking Increases Risk for Incident Metabolic Syndrome in Chinese Men—Shanghai Diabetes Study显示文摘Objective To determine whether smoking increases the risk for developing metabolic syndrome (MetS) in Chinese men.Methods A total of 693 men with no MetS at baseline were followed for 2.9‐5.5 years.Subjects were divided into nonsmokers,ex‐smokers,and current smokers according to baseline smoking status.Results After adjusting for age,education level,alcohol intake,fasting plasma insulin,HOMA‐IR index,and BMI at baseline and weight change,current smokers were dose‐dependently associated with increased risk for developing new MetS compared with nonsmokers.The odds ratio (OR) was 2.131 (95% CI,1.264,3.592;P<0.01) for the NCEPIII definition or 3.083 (95% CI,1.807,5.295;P<0.01) for the JCDCG definition of MetS.Ex‐smokers who had quit for ≥13 years significantly decreased the risk for developing new MetS defined by the JCDCG definition.Compared with nonsmokers,current smokers were significantly associated with increased incidence of hypertriglyceridemia and low HDL‐C.Conclusion Smoking is a risk factor for developing MetS in Chinese men after adjusting for age,education level,alcohol intake,fasting plasma insulin,HOMA‐IR,BMI,and weight change.This could be due to an increased incidence of dyslipidemia.Smoking cessation for >13 years decreased the risk for developing MetS defined by the JCDCG definition.ZHU YunXia ZHANG MingLiang HOU XuHong LU JunXi PENG LiangPu GU HuiLin WANG Chen JIA WeiPing 2011Biomedical and Environmental Sciences2011,24,5:13
5吉林省德惠市土壤特性空间变异特征与格局显示文摘Based on regionalized variable theory, semivariograms of geo-statistics were used to research the spatial variation of soil properties quantitatively. The results showed that the semivariogram of soil organic matter is best described by spherical model, the best model for semivariograms of soil total N and available K is exponential models and that of available P belongs to linear with sill model. Those soil properties have different spatial correlations respectively, the lag of organic matter is the highest and that of available P is the lowest, the spatial correlation of N and available K belongs to moderate degree. Spatial heterogeneities are different too, the degree of organic matter and total N are higher, the degree of available K is in the next place and that of available P is the lowest. Influenced by the shape, topography and soil of the study area, all isotropies of available P are obvious in all directions while anisotropies of others are manifested. According to the analytical results, supported by GIS, Kriging and IDW methods are applied to describe and analyze the spatial distribution of soil properties. The results indicate that soil organic matter, total N and available K are distributed regularly from northeast to southwest, while available P is distributed randomly.李晓燕 张树文 王宗明 ZHANG Huilin 2004Journal of Geographical Sciences2004,14,4:11
6YB-1, a new biomarker of glioma progression, is associated with the prognosis of glioma patients显示文摘(YB-1 ) Y 盒子蛋白质 1 是在各种各样的癌症表示的多功能的细胞的蛋白质,并且是在癌症治疗的一个潜在的目标。尽管有证据出现,那 YB-1 在人的癌症起一个作用,在 glioma 的 YB-1 表示的临床的意义没被建立。在现在的学习,我们在 glioma 肿瘤调查了 YB-1 水平并且分析了在 YB-1 水平和恶意的 glioma 的等级之间的关系,与提供为在临床、基本的研究背景的 gliomas 的诊断和治疗的新想法的目的。108 个病人的一个总数,与等级的 gliomas 包括 14, 31, 30,和 33 分别地,我, II, III,和 IV 在这研究被包括。YB-1 的 mRNA 和蛋白质层次被发现在等级 IV 和降低等级的肿瘤之间显著地不同。在脑髓的液体的 YB-1 层次比在等级在等级 III 和 IV glioma 病人是显著地更高的我和 II 病人。染色的 Immunofluorescence 被用来在细胞质和原子核检测 YB-1 的层次,并且结果显示细胞内部的分发显著地与 glioma 的病理学的等级被联系。YB-1 的高水平与弄短的幸存被联系,建议 YB-1 起在人的 glioma 的前进的一个作用。Jin Zheng Jiangwei Zhang Guangyue Li Huilin Gong 2016Acta Biochimica et Biophysica Sinica2016,48,4:8
7Molecular dynamics simulations of microscopicstructure of ultra strong shock waves in dense helium显示文摘Hydrodynamic properties and structure of strong shock waves in classical dense helium are simulatedusing non-equilibrium molecular dynamics methods. The shock speed in the simulation reaches 100km/s and the Mach number is over 250, which are close to the parameters of shock waves in theimplosion process of inertial confinement fusion. The simulations show that the high-Mach-numbershock waves in dense media have notable differences from weak shock waves or those in dilute gases.These results will provide useful information on the implosion process, especially the structure of strongshock wave front, which remains an open question in hydrodynamic simulations.Hao Liu Wei Kang Qi Zhang Yin Zhang Huilin Duan X. T. He 2016Frontiers of physics2016,11,6:8
8Modeling and prediction for the acute toxicity of pesticide mixtures to the freshwater luminescent bacterium Vibrio qinghaiensis sp.-Q67显示文摘In China, water pollution by pesticide mixtures has constituted a serious environmental problem due to potential toxicity and bioaccumulation. But few pesticide combinations have exactly similar and dissimilar mechanisms of action. For this purpose, in tests with the freshwater luminescent bacterium (Vibrio qinghaiensis sp.-Q67), ten pesticides, including three herbicides and seven insecticides, were selected as test substances. Concentration response analysis was performed for ten individual substances, and for mixtures containing all ten substances in twelve different concentration ratios (based on UDCR and EECR methods). The observed mixture toxicity was compared with predictions by the two models, concentration addition (CA) and independent action (IA). The toxicity of the tested mixtures showed a good agreement with those predicted by the concept of CA except four UDCR mixtures: UD10-2, UD10-4, UD10-8 and UD10-10. To examine the influence of imidacloprid in the four UDCR mixtures (UD10-2, UD10-4, UD10-8, UD10-10), it was removed from the ten-pesticide mixtures and the remaining nine chemicals were combined at the same relative proportions based on the UDCR method (UD9-2, UD9-4, UD9-8, UD9-10). There was not significant departure from CA for the scattered points with the nine remaining pesticides omitting imidacloprid. Thus, imidacloprid may significantly influence the other pesticides due to its properties.Xuefei Zhou, Wenjing Sang, Shushen Liu, Yalei Zhang, Huilin GeState Key Laboratory of Pollution Control and Resources Reuse, Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China. 2010Journal of Environmental Sciences2010,22,3:7
9Changes in autophagy proteins in a rat model of spinal cord injury显示文摘ObjectiveAutophagy 涉及几 neurodegenerative 疾病,最近,它在尖锐大脑损害的角色赢得了增加的兴趣。针的绳索损害(SCI ) 经常导致永久神经病学的赤字。在这研究,因此,我们在 SCI 以后检验了连接 autophagy 的蛋白质(MAP-LC3 ) 的侧面在 SCIMethodsAdult 女 Sprague-Dawley 老鼠被使用并且随机划分了成控制和 SCI 组以后,调查 autophagy 的表达式是否贡献神经病学的赤字。所有率在 T 8-T10 水平收到了 laminectomy。那些在 SCI 组收到了针的绳索的背面的表面的另外的暴露,由重量落下损害列在后面。此后,我们在 12   由西方的污点分析调查了 MAP-LC3, beclin-1,组织蛋白酶 D 和 beclin-1-binding 蛋白质 bcl-2 的表示层次; h, 24   h, 3 d, 7 d, 21 d 和 28 d。有 Tukey 柱子 hoc 测试的单程的 ANOVA 被用来比较在 groups.ResultsWe 之间的数据当时,在 SCI 以后在 3 d 和 7 d 在 LC3 (LC3-II/LC3-I ) 的水平观察了重要增加与假冒的组相比。当 beclin-1 的水平和 beclin-1/bcl-2 的比率被发现从 12   增加了时; h 到 24  在损害以后的 h。组织蛋白酶 D 表示也在 7 d 被提高(P  <  0.01 ) 上面上的 .ConclusionBased 提及数据,我们建议 autophagy 在房间损害追随者 SCI 的表明起一个作用。Zhang Qin Huang Chen Meng Bin Tang Tiansi Yang Huilin 2014Chinese Journal of Traumatology2014,17,4:6
10Detection of long bones based on Barker code excited ultrasonic guided waves显示文摘Single pulse excited ultrasonic guided wave surfers high attenuation during the propagation in long bones.This results in small amplitude and low signal-to-noise ratio(SNR)of measured signals.Thus,the Barker code excitation is introduced into long bone detection to improve the quality of received signals,due to its efficiency in increasing amplitude and SNR.Both simulation and in vitro experiment were performed,and the results were decoded by the weighted match filter(WMF) and the finite impulse response- least squares inverse filter(FIRLSIF),respectively.The comparison between the results of Barker code excitation and sine pulse excitation was presented.For 13-bit Barker code excitation,WMF produced 13 times larger amplitude than sine pulse excitation,while FIR-LSIF achieved higher peak-sidelobe-level(PSL) of —63.59 dB and better performance in noise suppression.The results show that the Barker code excited guided waves have the potential to be applied to the long bone detection.ZHANG Huilin SONG Xiaojun TA De'an 2014Chinese Journal of Acoustics2014,33,2:5
11Chemical Characteristics and Environmental Significance of Fresh Snow Deposition on Urumqi Glacier No.1 of Tianshan Mountains, China显示文摘Ice and snow chemistry of alpine glaciers is crucial for the research of regional atmospheric environment change. Fresh snow samples were weekly collected from Urumqi Glacier No.1 in the Tianshan Mountains, Xin- jiang, China, and the chemical characteristics and seasonal variations of major ions, mineral dust, δ18O and trace metals were measured. Results show that the concentrations of major ions in the snow are Ca2+ > SO42-> NH4+ > NO3-> Cl-> Na+ > Mg2+ > K+, in which Ca2+ is the dominant cation, and SO42-is the dominant anion. All major ions have close positive correlations with each other except NO3-. δ18O shows positive correlation with air temperature change during the study period. Mineral dust particle and major ionic concentrations in fresh snow have obvious seasonal change, with high concentration in spring but low concentration in summer and autumn, which indicates that the chemical mass input from Asian dust activity to snow is very significant. Temporal changes of trace metals in fresh snow, e.g., Cd, Pb, Zn, Al, Fe, have shown that human-induced pollution of central Asian region also has large contribution to the snow chemistry on alpine glaciers of the Tianshan Mountains.LI Zhongqin 2010Chinese Geographical Science2010,20,5:5
12An algorithm for automatic identification of multiple developmental stages of rice spikes based on improved Faster R-CNN显示文摘Spike development directly affects the yield and quality of rice. We describe an algorithm for automatically identifying multiple developmental stages of rice spikes(AI-MDSRS) that transforms the automatic identification of multiple developmental stages of rice spikes into the detection of rice spikes of diverse maturity levels. The scales vary greatly in different growth and development stages because rice spikes are dense and small, posing challenges for their effective and accurate detection. We describe a rice spike detection model based on an improved faster regions with convolutional neural network(Faster R-CNN).The model incorporates the following optimization strategies: first, Inception_Res Net-v2 replaces VGG16 as a feature extraction network;second, a feature pyramid network(FPN) replaces single-scale feature maps to fuse with region proposal network(RPN);third, region of interest(Ro I) alignment replaces Ro I pooling, and distance-intersection over union(DIo U) is used as a standard for non-maximum suppression(NMS). The performance of the proposed model was compared with that of the original Faster R-CNN and YOLOv4 models. The mean average precision(m AP) of the rice spike detection model was92.47%, a substantial improvement on the original Faster R-CNN model(with 40.96% m AP) and 3.4%higher than that of the YOLOv4 model, experimentally indicating that the model is more accurate and reliable. The identification results of the model for the heading–flowering, milky maturity, and full maturity stages were within two days of the results of manual observation, fully meeting the needs of agricultural activities.Yuanqin Zhang Deqin Xiao Youfu Liu Huilin Wu 2022The Crop Journal2022,10,5:4
13The long non-coding RNA expression profile of Coxsackievirus A16 infected RD cells identified by RNA-seq显示文摘Coxsackievirus A16(CVA16) is one of major pathogens of hand, foot and mouth disease(HFMD) in children. Long non-coding RNAs(Inc RNAs) have been implicated in various biological processes,but they have not been associated with CVA16 infection. In this study, we comprehensively characterized the landscape of Inc RNAs of normal and CVA16 infected rhabdomyosarcoma(RD)cells using RNA-Seq to investigate the functional relevance of Inc RNAs. We showed that a total of 760 Inc RNAs were upregulated and 1210 Inc RNAs were downregulated. Out of these dysregulated Inc RNAs, 43.64% were intergenic, 22.31% were sense, 15.89% were intronic, 8.67% were bidirectional, 5.59% were antisense, 3.85% were s RNA host Inc RNAs and 0.05% were enhancer. Six dysregulated Inc RNAs were validated by quantitative PCR assays and the secondary structures of these Inc RNAs were projected. Moreover, we conducted a bioinformatics analysis of an Inc RNAs(ENST00000602478) to elucidate the diversity of modification and functions of Inc RNAs. In summary, the current study compared the dysregulated Inc RNAs profile upon CVA16 challenge and illustrated the intricate relationship between coding and Inc RNAs transcripts. These results may not only provide a complete picture of transcription in CVA16 infected cells but also provide novel molecular targets for treatments of HFMD.Yingying Shi Huilin Tu Xiong Chen Yingying Zhang Liujun Chen Zhongchun Liu Jiqun Sheng Song Han Jun Yin Biwen Peng Xiaohua He Wanhong Liu 2016Virologica Sinica2016,31,2:4
14Functional recovery and microenvironmental alterations in a rat model of spinal cord injury following human umbilical cord blood-derived mesenchymal stem cells transplantation显示文摘BACKGROUND: Transplantation of human umbilical cord blood-derived mesenchymal stem cells (MSCs) has been shown to benefit spinal cord injury (SCI) repair. However, mechanisms of microenvironmental regulation during differentiation of transplanted MSCs remain poorly understood. OBJECTIVE: To observe changes in nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and interleukin-8 (IL-8) expression following transplantation of human umbilical cord-derived MSCs, and to explore the association between microenvironment and neural functional recovery following MSCs transplantation. DESIGN, TIME AND SETTING: A randomized, controlled, animal experiment was performed at the Department of Orthopedics, First Affiliated Hospital of Soochow University from April 2005 to March 2007. MATERIALS: Human cord blood samples were provided by the Department of Gynecology and Obstetrics, First Affiliated Hospital of Soochow University. Written informed consent was obtained. METHODS: A total of 62 Wister rats were randomly assigned to control (n = 18), model (n = 22, SCI + PBS), and transplantation (n = 22, SCI + MSCs) groups. The rat SCI model was established using the weight compression method. MSCs were isolated from human umbilical cord blood and cultured in vitro for several passages. 5-bromodeoxyuridine (BrdU)-labeled MSCs (24 hours before injection) were intravascularly transplanted. MAIN OUTCOME MEASURES: The rats were evaluated using the Basso, Beattie and Bresnahan (BBB) locomotor score and inclined plane tests. Transplanted cells were analyzed following immunohistochemistry. Enzyme-linked immunosorbant assay was performed to determine NGF, BDNF, and IL-8 levels prior to and after cell transplantation. RESULTS: A large number of BrdU-positive MSCs were observed in the SCI region of the transplantation group, and MSCs were evenly distributed in injured spinal cord tissue 1 week after transplantation. BBB score and inclined plane test results revealed significant functional improvement in the transplantation group compared to the model group (P < 0.05), which was maintained for 2-3 weeks. Compared to the model group, NGF and BDNF levels were significantly increased in the injured region following MSCs transplantation at 3 weeks (P < 0.05), but IL-8 levels remained unchanged (P > 0.05). CONCLUSION: MSCs transplantation increased NGF and BDNF expression in injured spinal cord tissue. MSCs could promote neurological function recovery in SCI rats by upregulating NGF expression and improving regional microenvironments.Hongtao Zhang Huilin Yang Huanxiang Zhang Jing Qu 2010Neural Regeneration Research2010,5,3:3
15Surgical Treatment for the Proliferative Retinal Detachment Associated with Macular Hole in the Morning Glory Syndrome显示文摘Purpose: To evaluate the efficacy of vitrectomy with peripapillary photocoagulation and silicone oil tamponade for the proliferative retinal detachment associated with macular hole in children with morning glory syndrome. Methods: Eight children with morning glory syndrome (mean age 8.0±2.8 years; range 5~13 years) were included; all patients had unilateral eye disease and were initially misdiagnosed as having bilateral squint or amblyopia, with best corrected visual acuity <6/60. Five patients could not cooperate with the fundus examination and one patient had lens opacities.B-ultrasound confirmed that all eight patients had retinal detachment and optic disc dysplasia.All patients underwent standard 3-port pars plana vitrectomy surgery . (20G for three cases and 23G for five cases).At surgery,all patients were confirmed to have morning glory syndrome,macular hole, and proliferative retinal detachment;.two cases had a funnel shaped bulge. All the retinal detachments involved the macular area, and macular hole was detected in the abnormal expansion excavation of the optic disk. The epiretinal membrane and subretinal membrane were completely removed during surgery. Combined photocoagulation in the abnormal expansion excavation of the optic disk, and silicone oil tamponade were also performed. Results:All eyes achieved anatomical resolution of retinal detachment.After follow-ups ranging from eight months to four years,the visual function for all patients was improved by postoperative refractive correction associated with vision training. Best corrected visual acuity was 6/600 to 6/30 at the final follow-up, no retinal detachment recurred, and no silicone oil fluid entered the subretinal space. The silicone oil was successfully removed postoperatively after a mean of 1.5 years. Conclusion:Vitrectomy with peripapillary photocoagulation and silicone oil tamponade is effective in treating the proliferative retinal detachment associated with macular hole in children with morning glory syndrome. (Eye Science 2013;28:7-10)Yi Zhang Huilin Ou Tiepei Zhu 2013Eye Science2013,28,1:3
16Long-term clinical observation of patients with acute and chronic complete spinal cord injury after transplantation of Neuro Regen scaffold显示文摘Spinal cord injury(SCI)often results in an inhibitory environment at the injury site.In our previous studies,transplantation of a scaffold combined with stem cells was proven to induce neural regeneration in animal models of complete SCI.Based on these preclinical studies,collagen scaffolds loaded with the patients’own bone marrow mononuclear cells or human umbilical cord mesenchymal stem cells were transplanted into SCI patients.Fifteen patients with acute complete SCI and 51 patients with chronic complete SCI were enrolled and followed up for 2 to 5 years.No serious adverse events related to functional scaffold transplantation were observed.Among the patients with acute SCI,five patients achieved expansion of their sensory positions and six patients recovered sensation in the bowel or bladder.Additionally,four patients regained voluntary walking ability accompanied by reconnection of neural signal transduction.Among patients with chronic SCI,16 patients achieved expansion of their sensation level and 30 patients experienced enhanced reflexive defecation sensation or increased skin sweating below the injury site.Nearly half of the patients with chronic cervical SCI developed enhanced finger activity.These long-term follow-up results suggest that functional scaffold transplantation may represent a feasible treatment for patients with complete SCI.Fengwu Tang Jiaguang Tang Yannan Zhao Jiaojiao Zhang Zhifeng Xiao Bing Chen Guang Han Na Yin Xianfeng Jiang Changyu Zhao Shixiang Cheng Ziqiang Wang Yumei Chen Qiaoling Chen Keran Song Zhiwei Zhang Junjie Niu Lingjun Wang Qin Shi Liang Chen Huilin Yang Shuxun Hou Sai Zhang Jianwu Dai 2022Science China(Life Sciences)2022,65,5:3
17Functionalized periodic Au@MOFs nanoparticle arrays as biosensors for dual-channel detection through the complementary effect of SPR and diffraction peaks显示文摘准备 nanoparticle 穿的周期的 Au@metal 器官的框架(MOF )(MIL-100 (Fe )) 的一个灵巧、便宜的方法被开发。数组用单层在 situ 被制作是的胶体的晶体模板,在底层上由 Au 免职列在后面,并且退火。MIL-100 (Fe ) 涂层用简单溶剂在 nanospheres 上被使用热过程。准备周期的 Au@MIL-100 (Fe ) nanoparticle (NP ) 数组被二座山峰在可见系列描绘。第一座山峰表示 Au nanospheres 的表面电浆子回声(SPR ) ,和另外的山峰,或衍射达到顶点,在 NP 数组从周期的结构发源。在有 3-aminophenylboronic 酸 hemisulfate (PBA ) 的修正以后, Au@MIL-100 (Fe ) NP 数组与好选择展出了敏感回答到不同葡萄糖集中。这些回答能由于在 PBA 和葡萄糖分子之间的强壮的相互作用。衍射山峰在低葡萄糖集中(不到 12 公里) 是敏感的,而 SPR 山峰很快在高集中反应了。山峰因此在不同集中区域为葡萄糖察觉表明了令人满意的互补敏感。这些结果能被用来开发一个双隧道的生物传感器。我们也创造了一张标准图,它能被用来高效地监视血葡萄糖层次。建议策略能被扩大与不同识别代理人用 Au@MIL-100 (Fe ) NP 数组 functionalized 开发不同双隧道的传感器。Lifeng Hang Fei Zhou Dandan Men Huilin Li Xinyang Li Honghua Zhang Guangqiang Liu Weiping Cai Cuncheng Li Yue Li 2017Nano Research2017,10,7:3
18Parenting stress and affective symptoms in parents of autistic children显示文摘We examined parenting stress and mental health status in parents of autistic children and assessed factors associated with such stress. Participants were parents of 188 autistic children diagnosed with DSM-IV criteria and parents of 144 normally developing children. Parents of autistic children reported higher levels of stress, depression, and anxiety than parents of normally developing children. Mothers of autistic children had a higher risk of depression and anxiety than that did parents of normally developing children. Mothers compared to fathers of autistic children were more vulnerable to depression. Age, behavior problems of autistic children, and mothers' anxiety were significantly associated with parenting stress.GONG Yun DU YaSong LI HuiLin ZHANG XiYan AN Yu WU Bai-Lin 2015Science China(Life Sciences)2015,58,10:3
19A flexible conductive hybrid elastomer for high-precision stress/strain and humidity detection显示文摘Flexible and environment-responsive materials are essential for a large number of applications from artificial skin to wearable devices. The present study develops a flexible, ultra-low cost conductive hybrid elastomer(CHE), which possesses high responsive capabilities to stress/strain and humidity. CHE was composed of polydimethylsiloxane(PDMS) and starch hydrogel(SH), enabling great elasticity(56 kPa),high conductivity(10^(-2)S/m) and high sensitivity to external stimuli(gauge factor of CHE under stress and strain are 0.71 and 2.22, respectively, and sensitivity to humidity is 1.2 × 10^(-6)S/m per RH%). These properties render CHE a promising candidate for artificial skin and wearable electronics applications of continuously monitoring environmental information.Haoran Liu Zhenyi Zhang Jun Ge Xiao Lin Xinye Ni Huilin Yang Lei Yang 2019Journal of Materials Science & Technology2019,35,1:2
20New Occurrence of the Early Cambrian Chengjiang Fauna in Haikou, Kunming, Yunnan Province,and Study on Trilobitoidea显示文摘This paper gives a brief report on the new occurrence of the Early CambrianQiongzhusi’ an Chengjiang fauna in the Haikou area, Kunming and its assemblage feature andthe stratigraphic section of the horizon yielding these fossils. Eight genera and 8 species ofTrilobitoidea are described here, embracing Leanchoilia asiatica Luo et Hu (sp. nov.), Yohoiasinensis Luo et Hu (sp. nov.), Zhongxinia speciosa Luo et Hu (gen. et sp. nov.), Xandarellaspectuculum Hou et al., Dianchia mirabilis Luo et Hu (gen. et sp. nov.), Kuamaia lata Hou,Retifacies longispinus Luo et Hu (sp. nov.) and Sinoburius lunaris Hou et al.Luo Huilin Hu Shixue Zhang Shishan and Tao Yonghe Yunnan Institute of Geological Sciences, Kunming Yunnan Kunyang Phosphorite Mine, Jinning, Yunnan 1997Acta Geologica Sinica(English Edition)1997,71,2:2
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