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| 1 | Fault Diagnosis for Manifold Absolute Pressure Sensor(MAP) of Diesel Engine Based on Elman Neural Network Observer显示文摘Intake system of diesel engine is a strong nonlinear system, and it is difficult to establish accurate model of intake system; and bias fault and precision degradation fault of MAP of diesel engine can't be diagnosed easily using model-based methods. Thus, a fault diagnosis method based on Elman neural network observer is proposed. By comparing simulation results of intake pressure based on BP network and Elman neural network, lower sampling error magnitude is gained using Elman neural network, and the error is less volatile. Forecast accuracy is between 0.015?0.017 5 and sample error is controlled within 0?0.07. Considering the output stability and complexity of solving comprehensively, Elman neural network with a single hidden layer and with 44 nodes is presented as intake system observer. By comparing the relations of confidence intervals of the residual value between the measured and predicted values, error variance and failures in various fault types. Then four typical MAP faults of diesel engine can be diagnosed: complete failure fault, bias fault, precision degradation fault and drift fault. The simulation results show: intake pressure is observable and selection of diagnostic strategy parameter reasonably can increase the accuracy of diagnosis;the proposed fault diagnosis method only depends on data and structural parameters of observer, not depends on the nonlinear model of air intake system. A fault diagnosis method is proposed not depending system model to observe intake pressure, and bias fault and precision degradation fault of MAP of diesel engine can be diagnosed based on residuals. | WANG Yingmin ZHANG Fujun CUI Tao ZHOU Jinlong | 2016 | Chinese Journal of Mechanical Engineering2016，29，2： | 17 |
| 2 | Solvent additive-free ternary polymer solar cells with 16.27% efficiency显示文摘Ternary strategy has been commonly demonstrated as an efficient method to improve the performance of polymer solar cells(PSCs), which has great potential in application of PSCs due to the simple device fabrication. | Qiaoshi An Xiaoling Ma Jinhua Gao Fujun Zhang | 2019 | Science Bulletin2019，64，8： | 14 |
| 3 | DNA barcoding of 18 species of Bovidae显示文摘Genetic divergences of mitochondrial cytochrome c oxidase subunit I genes,known as DNA barcodes,have been used in species identification in the animal kingdom.Barcodes can assist field workers and taxonomists to determine groups in need of taxa analysis,and facilitate the recognition of appropriate populations and scales for conservation planning.In this study,18 species of Bovidae were selected to evaluate the effectiveness of DNA barcoding for species differentiation.The results showed that all but 2 species had unique DNA barcodes.The mean intraspecific variation was 0.63%,yielding a threshold of 6.3% for flagging putative species.The results supported the inference that barcode variation within species of mammals is somewhat higher than within other animal groups.The present study validated the effectiveness of barcoding for the identification of bovid species. | CAI YanSen ZHANG Liang SHEN FuJun ZHANG WenPing HOU Rong YUE BiSong LI Jing ZHANG ZhiHe | 2011 | Chinese Science Bulletin2011，56，2： | 10 |
| 4 | LncRNA Nron regulates osteoclastogenesis during orthodontic bone resorption显示文摘Activation of osteoclasts during orthodontic tooth treatment is a prerequisite for alveolar bone resorption and tooth movement.However,the key regulatory molecules involved in osteoclastogenesis during this process remain unclear.Long noncoding RNAs(lnc RNAs)are a newly identified class of functional RNAs that regulate cellular processes,such as gene expression and translation regulation.Recently,lnc RNAs have been reported to be involved in osteogenesis and bone formation.However,as the most abundant noncoding RNAs in vivo,the potential regulatory role of lnc RNAs in osteoclast formation and bone resorption urgently needs to be clarified.We recently found that the lnc RNA Nron(long noncoding RNA repressor of the nuclear factor of activated T cells)is highly expressed in osteoclast precursors.Nron is downregulated during osteoclastogenesis and bone ageing.To further determine whether Nron regulates osteoclast activity during orthodontic treatment,osteoclastic Nron transgenic(Nron c TG)and osteoclastic knockout(Nron CKO)mouse models were generated.When Nron was overexpressed,the orthodontic tooth movement rate was reduced.In addition,the number of osteoclasts decreased,and the activity of osteoclasts was inhibited.Mechanistically,Nron controlled the maturation of osteoclasts by regulating NFATc1 nuclear translocation.In contrast,by deleting Nron specifically in osteoclasts,tooth movement speed increased in Nron CKO mice.These results indicate that lnc RNAs could be potential targets to regulate osteoclastogenesis and orthodontic tooth movement speed in the clinic in the future. | Ruilin Zhang Junhui Li Gongchen Li Fujun Jin Zuolin Wang Rui Yue Yibin Wang Xiaogang Wang Yao Sun | 2020 | International Journal of Oral Science2020，12，2： | 9 |
| 5 | Facile synthesis and electrochemical sodium storage of CoS2 micro/nano-structures显示文摘我们报导合成和钴二硫化物的电气化学的钠存储(有各种各样的 micro/nano-structures 的公司 2) 。有 microscale 尺寸的公司 2 也被 nanoparticles 装配(经由一条灵巧的 solvothermal 线路或 nanooctahedrons 的 P 公司 2) 构造了固体(O 公司 2) 和空微观结构(H 公司 2) 由热水的方法制作了。在三形态学之中, H 公司 2 作为钠离子电池(亲族) 的阳极展出最大的分泌物能力和最好的率性能。而且, H 公司 2 交付 690 妈 | Xue Liu Kai Zhang Kaixiang Lei Fujun Li Zhanliang Tao Jun Chen | 2016 | Nano Research2016，9，1： | 8 |
| 6 | Non-linear Torsional Vibration Characteristics of an Internal Combustion Engine Crankshaft Assembly显示文摘Crankshaft assembly failure is one of the main factors that affects the reliability and service life of engines.The linear lumped mass method,which has been universally applied to the dynamic modeling of engine crankshaft assembly,reveals obvious simulation errors.The nonlinear dynamic characteristics of a crankshaft assembly are instructionally significant to the improvement of modeling correctness.In this paper,a general expression for the non-constant inertia of a crankshaft assembly is derived based on the instantaneous kinetic energy equivalence method.The nonlinear dynamic equations of a multi-cylinder crankshaft assembly are established using the Lagrange rule considering nonlinear factors such as the non-constant inertia of reciprocating components and the structural damping of shaft segments.The natural frequency and mode shapes of a crankshaft assembly are investigated employing the eigenvector method.The forced vibration response of a diesel engine crankshaft assembly taking into account the non-constant inertia is studied using the numerical integral method.The simulation results are compared with a lumped mass model and a detailed model using the system matrix method.Results of non-linear torsional vibration analysis indicate that the additional excitation torque created by non-constant inertia activates the 2nd order rolling vibration,and the additional damping torque resulting from the non-constant inertia is the main nonlinear factor.The increased torsional angular displacement evoked by the high order excitation torque relates to the non-constant inertia.This research project is aimed at improving nonlinear dynamics theory,and the confirmed nonlinear parameters can be used for the structure design of a crankshaft assembly. | HUANG Ying YANG Shouping ZHANG Fujun ZHAO Changlu LING Qiang WANG Haiyan | 2012 | Chinese Journal of Mechanical Engineering2012，25，4： | 7 |
| 7 | Analysis of characteristics and predictive factors of immune checkpoint inhibitor-related adverse events显示文摘Objective:We aimed to retrospectively analyze the toxicity profiles and predictors of immune-related adverse events(irAEs)as well as the correlation between irAEs and the clinical efficacy of multi-type immune checkpoint inhibitors(ICIs)in patients with advanced pan-cancer in a real-world setting.Methods:We retrospectively analyzed data from 105 patients with advanced pan-cancer treated with multi-type ICIs at the First Hospital of Jilin University between January 1,2016 and August 1,2020.We used logistic regression analyses to investigate the associations of irAEs with clinical baseline characteristics,blood count parameters,and biochemical indicators during treatment.Receiver operating characteristic curves were used to determine cutoff values for parameters and area under the curve values.Kaplan–Meier and Cox multivariate regression analyses were performed to estimate the relationships of baseline characteristics and irAEs with progression-free survival(PFS)and overall survival(OS).Results:A lower relative lymphocyte count(cutoff=28.5%),higher albumin level(cutoff=39.05 g/L),and higher absolute eosinophil count(AEC)(cutoff=0.175×10^(9)/L)were significantly associated with the occurrence of irAEs,among which a higher AEC(cutoff=0.205×10^(9)/L)was strongly associated with skin-related irAEs[odds ratios(ORs)=0.163,P=0.004].Moreover,a higher lactate dehydrogenase level(cutoff=237.5 U/L)was an independent predictor of irAEs of grade≥3(OR=0.083,P=0.023).In immune cell subgroup analysis,a lower absolute count of CD8+CD28−suppressor T cells(OR=0.806;95%confidence interval:0.643–1.011;P=0.062),which are regulatory T lymphocytes,was associated with the occurrence of irAEs,although the difference was not statistically significant.Furthermore,a higher percentage of CD19+B cells was associated with the occurrence of irAEs of grade≥3(P=0.02)and grade≥2(P=0.051).In addition,patients with any grade of irAE had a significantly high PFS(8.37 vs.3.77 months,hazard ratios(HR)=2.02,P=0.0038)and OS(24.77 vs.13.83 months,HR=1.84;P=0.024).Conclusions:This retrospective study reports clinical profile data for irAEs in unselected patients in a real-world setting and explored some parameters that may be potential predictive markers of the occurrence,type,or grade of irAEs in clinical practice.Evidence of a correlation between safety and efficacy may facilitate a complete assessment of the risk-benefit ratio for patients treated with ICIs. | Rilan Bai Naifei Chen Xiao Chen Lingyu Li Wei Song Wei Li Yuguang Zhao Yongfei Zhang Fujun Han Zheng Lyu Jiuwei Cui | 2021 | Cancer Biology & Medicine2021，18，4： | 4 |
| 8 | Over 16.7% efficiency of ternary organic photovoltaics by employing extra PC71BM as morphology regulator显示文摘Ternary organic photovoltaics(OPVs)are fabricated with PBDB-T-2 Cl:Y6(1:1.2,wt/wt)as the host system and extra PC71BM as the third component.The PBDB-T-2 Cl:Y6 based binary OPVs exhibit a power conversion efficiency(PCE)of 15.49%with a short circuit current(JSC)of 24.98 mA cm^-2,an open circuit voltage(VOC)of 0.868 V and a fill factor(FF)of 71.42%.A 16.71%PCE is obtained in the optimized ternary OPVs with PBDB-T-2 Cl:Y6:PC71BM(1:1.2:0.2,wt/wt)active layer,resulting from the synchronously improved JSC of 25.44 mA cm^-2,FF of 75.66%and the constant VOCof 0.868 V.The incorporated PC71BM may prefer to mix with Y6 to finely adjust phase separation,domain size and molecular arrangement in ternary active layers,which can be confirmed from the characterization on morphology,2 D grazing incidence small and wide-angle X-ray scattering,as well as Raman mapping.In addition,PC71BM may prefer to mix with Y6 to form efficient electron transport channels,which should be conducive to charge transport and collection in the optimized ternary OPVs.This work provides more insight into the underlying reasons of the third component on performance improvement of ternary OPVs,indicating ternary strategy should be an efficient method to optimize active layers for synchronously improving photon harvesting,exciton dissociation and charge transport,while keeping the simple cell fabrication technology. | Jinhua Gao Jian Wang Qiaoshi An Xiaoling Ma Zhenghao Hu Chunyu Xu Xiaoli Zhang Fujun Zhang | 2020 | Science China Chemistry2020，63，1： | 4 |
| 9 | Preparation of monoclonal antibody against human KIAA0100 protein and Northern blot analysis of human KIAA0100 gene显示文摘Monoclonal antibodies(MAbs) are important tools for the study of proteins′ function and structure. But there has been no report on the preparation of MAbs against human KIAA0100 protein up to date. Here, first, we generated the mouse MAb against human KIAA0100 protein using purified recombinant 6×Histidinc(6×His)-tagged human KIAA0100 protein segment(1557–2234) as an antigen; then, the m RNA expression of human KIAA0100 gene was detected in U937 cells using Northern blot analysis. The results showed that the mouse MAb against human KIAA0100 protein could sensitively recognize the human KIAA0100 protein using Western blot analysis and immunocytochemistry analysis. Besides, Western blot analysis revealed that human KIAA0100 gene possibly encoded two different protein products(254 k Da and < 250 k Da) in U937 cells. Moreover,Northern blot analysis confirmed that human KIAA0100 gene might produced two different m RNA products(6000–10000 bp and 5000–6000 bp) in U937 cells. The results provide a basis for large-scale production of the MAb against human KIAA0100 protein, which will be useful for the study of human KIAA0100 protein′s function/structure and MAb-targeted drugs in the future. | He Cui Xi Lan Shemin Lu Fujun Zhang Wanggang Zhang | 2017 | Journal of Pharmaceutical Analysis2017，7，3： | 4 |
| 10 | Microsatellite variability reveals high genetic diversity and low genetic differentiation in a critical giant panda population显示文摘 | Jiandong YANG Zhihe ZHANG Fujun SHEN Xuyu YANG Liang ZHANG Limin CHEN Wenping ZHANG Qing ZHU Rong HOU | 2011 | Current Zoology2011，57，6： | 3 |
| 11 | Approaching 18%efficiency of ternary organic photovoltaics with wide bandgap polymer donor and well compatible Y6:Y6-1O as acceptor显示文摘A series of ternary organic photovoltaics(OPVs)are fabricated with one wide bandgap polymer D18-Cl as donor,and well compatible Y6 and Y6-1O as acceptor.The open-circuit-voltage(V_(OC))of ternary OPVs is monotonously increased along with the incorporation of Y6-1O,indicating that the alloy state should be formed between Y6 and Y6-1O due to their excellent compatibility.The energy loss can be minimized by incorporating Y6-1 O,leading to the V_(OC)improvement of ternary OPVs.By finely adjusting the Y6-1O content,a power conversion efficiency of 17.91%is achieved in the optimal ternary OPVs with 30 wt%Y6-1O in acceptors,resulting from synchronously improved short-circuit-current density(JSC)of 25.87 mA cm^(-2),fill factor(FF)of 76.92%and V_(OC)of 0.900 V in comparison with those of D18-Cl:Y6 binary OPVs.The JSC and FF improvement of ternary OPVs should be ascribed to comprehensively optimal photon harvesting,exciton dissociation and charge transport in ternary active layers.The more efficient charge separation and transport process in ternary active layers can be confirmed by the magnetophotocurrent and impedance spectroscopy experimental results,respectively.This work provides new insight into constructing highly efficient ternary OPVs with well compatible Y6 and its derivative as acceptor. | Xiaoling Ma Anping Zeng Jinhua Gao Zhenghao Hu Chunyu Xu Jae Hoon Son Sang Young Jeong Caixia Zhang Mengyang Li Kai Wang He Yan Zaifei Ma Yongsheng Wang Han Young Woo Fujun Zhang | 2021 | National Science Review2021，8，8： | 3 |
| 12 | Modeled response of talik development under thermokarst lakes to permafrost thickness on the Qinghai-Tibet Plateau显示文摘Permafrost thickness under identical climates in cold regions can vary significantly because it is severely affected by climate change, topography, soil physical and thermal properties, and geothermal conditions. This study numerically investigates the response of ground thermal regime and talik development processes to permafrost with different thicknesses under a thermokarst lake on the Qinghai-Tibet Plateau. On the basis of observed data and information from a representative monitored lake in the Beiluhe Basin, we used a heat transfer model with phase change under a cylindrical coordinate system to conduct three simulation cases with permafrost thicknesses of 45 m, 60 m, and 75 m, respectively. The simulated results indicate that increases in permafrost thickness not only strongly retarded the open talik formation time, but also delayed the permafrost lateral thaw process after the formation of open talik. Increasing the permafrost thickness by 33.3% and 66.7% led to open talik formation time increases of 83.66% and 207.43%, respectively, and resulted in increases in the lateral thaw duration of permafrost under the modeled thermokarst lake by 28.86% and 46.54%, respectively, after the formation of the open taliks. | Feng Ling QingBai Wu FuJun Niu TingJun Zhang | 2014 | Research in Cold and Arid Regions2014，6，6： | 3 |
| 13 | 14.46% Efficiency small molecule organic photovoltaics enabled by the well trade-off between phase separation and photon harvesting显示文摘Small molecule organic photovoltaics(SMPVs) were prepared by utilizing liquid crystalline donor material BTR-Cl and two similar optical bandgap non-fullerene acceptor materials BTP-BO-4 F and Y6.The BTPBO-4 F and Y6 have the similar optical bandgap and different absorption coefficients.The corresponding binary SMPVs exhibit different short circuit current density(/sc)(20.38 vs.23.24 mA cm^(-2)),and fill factor(FF)(70.77% vs.67.21%).A 14.46% power conversion efficiency(PCE) is acquired in ternary SMPVs with 30 wt% Y6,companied with a JSC of 24.17 mA cm^(-2) a FF of 68.78% and an open circuit voltage(Voc) of 0.87 V.The improvement on PCE of ternary SMPVs should originate from the well trade-off between phase separation and photon harvesting of ternary active layers by incorporating 30 wt% Y6 in acceptors.This work may deliver insight onto the improved performance of SMPVs by superposing the superiorities of binary SMPVs with similar optical bandgap acceptors into one ternary cell. | Chunyu Xu Haiyan Chen Zijin Zhao Jinhua Gao Xiaoling Ma Shirong Lu Xiaoli Zhang Zeyun Xiao Fujun Zhang | 2021 | Journal of Energy Chemistry2021，30，6： | 2 |
| 14 | Confining sulfur in intact freestanding scaffold of yolk-shell nanofibers with high sulfur content for lithium-sulfur batteries显示文摘Nanostructure design holds great potential in fabricating sulfur electrodes that host a high sulfur loading and still attain high electrochemical utilization for the developing of high-energy-density lithium-sulfur(Li-S) batteries. In this contribution, we introduce the yolk-shell structure into a freestanding carbon nanofibers film and construct a complete hollow yolk-shell Ti O2/carbon nanofibers@void@TiN@carbon(TiO2-CNFs@void@Ti N@C) composite. With inherent double conductive network and strong adsorption capability for polysulfides, the Ti O2-CNFs@void@Ti N@C composite can not only provide sufficient electrical contact for the insulating sulfur, but also effectively entrap polysulfides for prolonged cycle life. As a result, an excellent capacity retention ratio of 60.9% after 1000 cycles at 1 C as well as a high capacity of688.5 mA h g^(-1) at 5 C rate is accomplished with the cells employing Ti O2-CNFs@void@TiN @C as a cathode substrate for sulfur. Moreover, the TiO2-CNFs@void@Ti N@C composite, with a high S mass loading of9.5 mg cm^(-2), delivers a superb areal capacity of 8.2 mAh cm^(-2). | Xilai Zhang Peng Zhang Shijie Zhang Yongshang Zhang Ruohan Hou Kangli Liu Fujun Miao Guosheng Shao | 2020 | Journal of Energy Chemistry2020，29，12： | 2 |
| 15 | Organic photovoltaic cells:Novel organic semiconducting materials and molecular arrangement engineering显示文摘Organic photovoltaic cells(OPVs) have attracted more and more attention due to its highly potential application to solve the energy crisis considering its advantages,such as low cost and ease of large area production.The power conversion efficiency(PCE) of OPVs has undergone a more than nine-fold increase from ~1.0% by Tang in 1986 to 9.2% in 2010 announced by Mitsubishi Chemical.The major challenges of obtaining high efficiency OPVs are the synthesis of new narrow band gap materials,controlling molecular arrangement,designing novel configuration cells for better photon harvesting in the active layer.In the article,we summarized the recent progress of novel narrow band gap photovoltaic materials and the effective methods to control the morphology of donor and acceptor in the blend films for high performance of OPVs. | WANG ZiXuan ZHANG FuJun WANG Jin XU XiaoWei WANG Jian LIU Yang XU Zheng | 2012 | Chinese Science Bulletin2012，57，32： | 2 |
| 16 | Preharvest application of 1-methylcyclopropene and Ethephon altered cuticular wax biosynthesis and fruit quality of apples at harvest and during cold storage显示文摘To investigate the roles of Harvista(a sprayable 1-methylcyclopropene,1-MCP,available component is 150 g·hm^(-2))and Ethephon(1 mL·L^(-1))applied at preharvest in apple(Malus domestica Borkh.'Golden Delicious')fruit cuticular wax biosynthesis,the expression of genes related to fruit cuticular wax biosynthesis and ethylene biosynthesis and signaling,ethylene production rate,respiration rate,wax constituents and structure,and fruit quality were determined at harvest and during cold storage.The results showed that 1-MCP inhibited the expression levels of ethylene biosynthesis and signaling-related genes,decreased fruit ethylene production,and inhibited the expression of Md LACS1,Md CER6,Md CER4 and Md WSD1,which resulted in decreases in alcohols,acids,and esters content in fruit cuticular wax.1-MCP also reduced fruit dropping rate from 17.17%to 12%;maintained fruit firmness,soluble solids,titratable acidity during cold storage;showed about as one fifth in the total length and one third in the widest width of wax crack as that in control at harvest.In contrast,Ethephon produced the opposite effects.In conclusion,1-MCP inhibited fruit ethylene biosynthesis and signaling,and influenced fruit cuticular wax biosynthesis.Thus,the fruit cuticular wax constituents and structure was altered,and the fruit quality were maintained at harvest and during cold storage.The results provide a new technology for improving apple fruit harvest and postharvest quality by preharvest application of sprayable 1-MCP. | Fujun Li Xinyue Zhang Jihan Wang Yaping Jiang Xinhua Zhang Xiaoan Li | 2022 | Horticultural Plant Journal2022，8，2： | 2 |
| 17 | Investigation on the combustion characteristics of a diesel engine fueled with diesel–azides blends显示文摘 | Geng Fu Changlu Zhao Bolan Liu Fujun Zhang Siping Pang Yuchuan Li | 2011 | Applied Energy2011，，1： | 2 |
| 18 | Dynamic features of near-inertial oscillations in the Northwestern Pacific derived from mooring observations from^2015 to 2018显示文摘Near-inertial oscillation is an important physical process transferring surface wind energy into deep ocean.We investigated the near-inertial kinetic energy(NIKE)variability using acoustic Doppler current profiler measurements from a mooring array deployed in the tropical western Pacific Ocean along 130°E at 8.5°N,11°N,12.6°N,15°N,and 17.5°N from September 2015 to January 2018.Spatial features,decay timescales,and significant seasonal variability of the observed NIKE were described.At the mooring sites of 17.5°N,15°N,and 12.6°N,the NIKE peaks occurred in boreal autumn and the NIKE troughs were observed in boreal spring.By contrast,the NIKE at 11°N and 8.5°N showed peaks in winter and troughs in summer.Tropical cyclones and strong wind events played an important role in the emergence of high-NIKE events and explained the seasonality and latitudinal characteristics of the observed NIKE. | HU Shijian LIU Lingling GUAN Cong ZHANG Linlin WANG Jianing WANG Qingye MA Jie WANG Fujun JIA Fan FENG Junqiao LU Xi WANG Fan HU Dunxin | 2020 | Journal of Oceanology and Limnology2020，38，4： | 2 |
| 19 | Anti-Toll-like receptor 2 antibody inhibits nuclear factor kappa B activation and attenuates cardiac damage in high-fat-feeding rats显示文摘Long-time con sumption of high-fat food is a direct cause of cardiovascular diseases, and high-fatrelated inflammation plays an important role in it. Toll-like receptors (TLRs), especially TLR2 and TLR4, play important roles in high-fat-related inflammation. However, the impact of TLR2 on high-fatassociated cardiovascular complications is still unknown. In this study, we try to investigate the relationship between TLR2 and high-fat-related cardiac injury. SD rats were allocated to either a control group which were fed with normal diet or a high-fat group which were fed with high-fat diet for 5 months. At the last mon th, rats fed with high-fat diet were intraperitoneally injected with control normal mouse IgG or anti-TLR2 antibody. Heart tissues were collected for further analysis. RT-qPCR and western blot analysis results revealed that TLR2 expression was increased in the heart tissues from rats fed with high-fat diet and anti-TLR2 antibody had no effect on TLR2 expression. However, anti- TLR2 antibody alleviated masson staining area, levels of TGF-pi and Collagen I mRNA, and decreased TUNEL-positive myocardial cells and caspase-3 activity, suggesting that anti-TLR2 antibody protected cardiac cells against high-fat-induced cardiac fibrosis and cell apoptosis. By using immunohistochemistry, RT-qPCR and ELISA, we found that anti-TLR2 antibody blocked NF-kB activation, inhibited the expression of inflammatory factors such as TNF-a, IL-1,IL-6 and IL-18 in the heart tissues from rats fed with high-fat diet. These results hinted that anti-TLR2 antibody might exert its protective effect via inhibition of the TLR2/NF-KB/inflammation pathway. Our findings suggest that anti-TLR2 antibody has a preventive function against high-fat-induced deleterious effects in the heart, and anti-TLR2 antibody may be used as an attractive therapeutic option for high-fat-induced cardiac injury. | Wanzheng Wang Litao Wu Xiaojuan Du Fujun Zhang Sayyed Hanif Ullah Ting Lei Dongming Li Xiaofei Yan | 2019 | Acta Biochimica et Biophysica Sinica2019，51，4： | 2 |
| 20 | Piezoelectric Actuator Placement Optimization and Active Vibration Control of a Membrane Structure显示文摘The placement optimization of piezoelectric actuators and active vibration control of a membrane structure are studied in this paper. The classical linear quadratic regulator controllers are designed to suppress the unwanted vibration. Simulation results indicate that the optimal locations of piezoelectric actuators are affected deeply by the additional mass and stiffness of actuators, the computational efficiency of particle swarm optimizer is higher than that of genetic algorithm for this particular problem, and the control performance of optimally placed actuators is better than that of non-optimally placed actuators. | Xiang Liu Guoping Cai Fujun Peng Hua Zhang | 2018 | Acta Mechanica Solida Sinica2018，31，1： | 2 |
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