|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 中国慢性病的挑战与应对显示文摘中国在短短几十年内,完成了从传染病向慢性病的流行病学模式转变,转变速度远远高于其他许多国家。而行为模式的转变,包括膳食习惯变化、体力活动减少、高水平的男性吸烟率等危险因素是中国疾病模式快速转变的重要原因。其结果是,这些本可避免的慢性病的发病率和死亡率快速上升。引发了医疗卫生服务费用显著上升。目前,中国有1.77亿高血压患者,有3.03亿烟民(占世界烟民的1/3),并有5.3亿人遭受被动吸烟危害。 | Gonghuan Yang Lingzhi Kong Wenhua Zhao Xia Wan Yi Zhai Lincoln C Chen Jeffrey P Koplan | 2008 | 世界临床医学2008，2，6： | 5 |
| 2 | Rapid phenotypic evolution with shallow genomic differentiation during early stages of high elevation adaptation in Eurasian Tree Sparrows显示文摘Known as the‘third polar region’,the Qinghai-Tibet Plateau represents one of the harshest highland environments in the world and yet a number of organisms thrive there.Previous studies of birds,animals and humans have focused on well-differentiated populations in later stages of phenotypic divergence.The adaptive processes during the initial phase of highland adaptation remain poorly understood.We studied a human commensal,the Eurasian Tree Sparrow,which has followed human agriculture to the Qinghai-Tibet Plateau.Despite strong phenotypic differentiation at multiple levels,in particular in muscle-related phenotypes,highland and lowland populations show shallow genomic divergence and the colonization event occurred within the past few thousand years.In a one-month acclimation experiment investigating phenotypic plasticity,we exposed adult lowland tree sparrows to a hypoxic environment and did not observe muscle changes.Through population genetic analyses,we identified a signature of polygenic adaptation,whereby shifts in allele frequencies are spread across multiple loci,many of which are associated with muscle-related processes.Our results reveal a case of positive selection in which polygenic adaptation appears to drive rapid phenotypic evolution,shedding light on early stages of adaptive evolution to a novel environment. | Yanhua Qu Chunhai Chen Ying Xiong Huishang She Yong E Zhang Yalin Cheng Shane DuBay Dongming Li Per G P Ericson Yan Hao Hongyuan Wang Hongfeng Zhao Gang Song Hailin Zhang Ting Yang Chi Zhang Liping Liang Tianyu Wu Jinyang Zhao Qiang Gao Weiwei Zhai Fumin Lei | 2020 | National Science Review2020，7，1： | 2 |
| 3 | NAD synthase nmnat acts as a chaperone to protect against neurodegeneration显示文摘 | Zhai R G Zhang F Hiesinger P R Cao Y Haueter C M Bellen H J | 2008 | Nature2008，452，： | 1 |
| 4 | Genetic analysis of a novel dominant rice dwarf mutant 986083D显示文摘 | Qin R Z Qiu Y Cheng Z J Shan X Y Guo X P Zhai H Q Wan J M | 2008 | Euphytica2008，160，： | 1 |
| 5 | Classification of asphalt binders into simple and complex binders 显示文摘 | Bahia H U Hislop W P Zhai H | 1998 | Journal of the Association of Asphalt Paving Technolo- gists1998，67，： | 1 |
| 6 | Atmospheric water vapor over China显示文摘 | Zhai P M Eskridge R E | 1997 | Journal of Climate1997，10，10： | 1 |
| 7 | The regulatory roles of microRNA-146 b-5 p and its target platelet-derived growth factor receptor alpha (PDGFRA) in erythropoiesis and megakaryocytopoiesis 显示文摘 | ZHAI P F WANG F SU R | 2014 | J Biol Chem2014，289，22： | 1 |
| 8 | Trihalomethane formation of Maeao water supply eontaminated by seawater intrusion显示文摘 | Zhai X D Liu J F Zhu X P | 2006 | Journal of Harbin University of Commerce2006，22，1： | 1 |
| 9 | Atmospheric water vapor over China显示文摘 | Zhai P M R E Eskridge | 1997 | J Climate1997，10，： | 1 |
| 10 | A modified ultrasonic linear motor显示文摘 | Zhai B Lim S P Lee K H | | 0，，03： | 1 |
| 11 | Oxidative stress stim- ulates autophagie flux during ischemia/reperfusion 显示文摘 | HARIHARAN N ZHAI P SADOSHIMA J | 2011 | Antioxida- nts and Redox Signaling2011，14，11： | 1 |
| 12 | Atmospheric water vapor over China显示文摘 | Zhai P M Eskridge R E | 1997 | J Climate1997，10，： | 1 |
| 13 | DEVELOPMENT OF Sr0.69La0.31F2.31+SrSSOLID ELECTROLYTE SENSOR AND ITS APPLICATION显示文摘DEVELOPMENTOFSr0.69La0.31F2.31+SrSSOLIDELECTROLYTESENSORANDITSAPPLICATIONZhai;YuchunMa;PingTian;YanwenXiao;FeiJi;Chun?.. | ZHAI, YC MA, P TIAN, YW XIAO, F JI, CL | 1995 | 中国有色金属学会会刊:英文版1995，5，1： | 1 |
| 14 | Changes of climate extremes in China显示文摘 | Sum A J Ren Fumin | 1999 | Climatic Change1999，42，： | 1 |
| 15 | Response characteristic of domestic dosimeter glass to recording fission tracks显示文摘 | Zhao Y | 1997 | Radiation Measurements1997，28，57： | 1 |
| 16 | Thioredoxin 1 negatively regulates an-giotensinⅡ-induced cardiac hypertrophy through upregulation of miR-98/let-7显示文摘 | Yang Y Ago T Zhai P | 2011 | Circ Res2011，108，3： | 1 |
| 17 | Europ Polym J显示文摘 | Xu W B Liang G D Zhai H B Tang S P Hang G P Pan W P | 2003 | 39:1 4672003，39，： | 1 |
| 18 | Mstl inhibits autophagy by pro- moting Beclinl-Bcl-2 interaction 显示文摘 | Maejima Y Kyoi S Zhai P | 2013 | Nat Med2013，19，11： | 1 |
| 19 | A dominancebased rough set approach to Kansei engineering in product development显示文摘 | ZHAI L Y KHOO L P ZHONG Z W | 2009 | Expert Systems with Applications2009，，36： | 1 |
| 20 | High-pressure granulites in the Sangan area, North China Craton: metamorphic evolution, p-T paths and geotectonic significance 显示文摘 | Guo J H O'Bfien P J Zhai M G | 2002 | Journal of Metamorphic Geology2002，20，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员