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| 1 | The complete reference genome for grapevine (Vitis vinifera L.) genetics and breeding显示文摘Grapevine is one of the most economically important crops worldwide.However,the previous versions of the grapevine reference genome tipically consist of thousands of fragments with missing centromeres and telomeres,limiting the accessibility of the repetitive sequences,the centromeric and telomeric regions,and the study of inheritance of important agronomic traits in these regions.Here,we assembled a telomere-to-telomere(T2T)gap-free reference genome for the cultivar PN40024 using PacBio HiFi long reads.The T2T reference genome(PN_T2T)is 69 Mb longer with 9018 more genes identified than the 12X.v0 version.We annotated 67%repetitive sequences,19 centromeres and 36 telomeres,and incorporated gene annotations of previous versions into the PN_T2T assembly.We detected a total of 377 gene clusters,which showed associations with complex traits,such as aroma and disease resistance.Even though PN40024 derives from nine generations of selfing,we still found nine genomic hotspots of heterozygous sites associated with biological processes,such as the oxidation–reduction process and protein phosphorylation.The fully annotated complete reference genome therefore constitutes an important resource for grapevine genetic studies and breeding programs. | Xiaoya Shi Shuo Cao Xu Wang Siyang Huang Yue Wang Zhongjie Liu Wenwen Liu Xiangpeng Leng Yanling Peng Nan Wang Yiwen Wang Zhiyao Ma Xiaodong Xu Fan Zhang Hui Xue Haixia Zhong Yi Wang Kekun Zhang Amandine Velt Komlan Avia Daniela Holtgräwe Jérôme Grimplet JoséTomás Matus Doreen Ware Xinyu Wu Haibo Wang Chonghuai Liu Yuling Fang Camille Rustenholz Zongming Cheng Hua Xiao Yongfeng Zhou | 2023 | Horticulture Research2023，10，5： | 3 |
| 2 | Changes in outlook following disaster:The preliminary development of a measure to assess positive and negative responses显示文摘 | Joseph S Williams R Yule W | | 0，，02： | 1 |
| 3 | Secretagogues cause ubiquitination and down-regulation of inositol 1,4,5-trisphosphate receptors in rat pancreatic acinar cells显示文摘 | Wojcikiewicz R J Ernst S A Yule D I | 1999 | Gastroenterology1999，116，： | 1 |
| 4 | Post-traumatic stress : Attributional aspects显示文摘 | Joseph S Yule W Williams R | 1993 | Journal of Traumatic Stress1993，6，4： | 1 |
| 5 | Sexual behaviour and smoking as determinants of cervical HPV infection and of CINⅢ among those infected: a case - control study nested within the Manchester cohort显示文摘 | Deacon JM Evans CD Yule R | 2000 | Br J Cancer2000，88，： | 1 |
| 6 | Sexual behaviour and smoking as determinants of cervical HPV infection and of CIN3among those infected:a case - control study nested within the Machester cohort 显示文摘 | Deacon JM Evans CD Yule R | 2000 | Br J Cancer2000，83，11： | 1 |
| 7 | Sexual behaviour and smoking as determinants of ceryical HPV infection and of CIN3 among those infected: a case- control study nested within the Manchester cohort显示文摘 | Deacon JM Evans CD Yule R | 2000 | Br J Cancer2000，83，： | 1 |
| 8 | Leadership for safety: Industrial experience显示文摘 | Flin R Yule S | 2004 | Quality and Safety in Health Care2004，13，： | 1 |
| 9 | Increase egg production in juvenile turkey hens after active immunization with vasoactive intestinal peptide显示文摘 | Caldwell S R Johnson A F Yule T D | 1999 | Poultry Science1999，78，： | 1 |
| 10 | Acute stress disorder and posttraumatic stress disorder in children and adolescents involved in assaults or motor vehicle accidents 显示文摘 | Meiser-Stedman R Yule W Smith P | 2005 | Am J Psychiatry2005，162，： | 1 |
| 11 | Express: A Web-based technology to support human and computational experimentation 显示文摘 | Yule P Cooper R P | 2003 | Behavior Research Methods Instruments & Computers2003，35，： | 1 |
| 12 | Evidence for a great medieval earthquake(~1100 AD)in the central Himalayas,Nepal显示文摘 | Lavé J Yule D Sapkota S Basant K Madden C Attal M Pandey R | | 0，，5713： | 1 |
| 13 | Acute stress disorder and posttraumatic stress disorder in children and adolescents in- volved in assaults and motor vehicle accidents显示文摘 | Meiser Stedman R Yule W Smith P | 2005 | American Jour- nal of Psychiatry2005，162，13： | 1 |
| 14 | The role of management and safety climate in preventing risk-taking at work显示文摘 | Yule S Flin R Murdy A | 2007 | International Journal of Risk Assessment and Management2007，7，2： | 1 |
| 15 | The Effect of Multiple Internal Reflections on the Densities of Halftone Prints on Paper显示文摘 | CLAPPER F R YULE J A C | 1953 | Opt Soc Am1953，43，7： | 1 |
| 16 | Causal attributions and psychiatric symptoms in survivors of the Herald of Free Enterprise disaster显示文摘 | JOSEPH S A BREWIN C R YULE W | 1991 | Br J Psychiatry1991，159，： | 1 |
| 17 | The effect of multiple internal reflections on the densities of halftone prints on paper显示文摘 | Clapper F R Yule J A C | 1953 | Journal of the Optical Society of America1953，43，7： | 1 |
| 18 | The Effect of Multiple Inter-nal Reflections on the Densities of Halftone Prints on Paper 显示文摘 | CLAPPER F R YULE J A C | 1953 | Opt Soc Am1953，43，7： | 1 |
| 19 | Tobacco Rar1,EDS1 and NPR1/NIM1 like genes are required for N-mediated resistance to tobacco mosaic virus显示文摘 | Liu Yule Schiff M Marathe R | 2002 | The Plant Journal2002，30，4： | 1 |
| 20 | The effect of multiple internal reflections on the densities of halftone prints on paper显示文摘 | CLAPPER F R YULE J A C | 1953 | Journal of the Optical Society of America1953，43，7： | 1 |
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