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| 1 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 2 | Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。 | R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren | 2011 | Cell Research2011，21，10： | 6 |
| 3 | Femtojoule electro-optic modulation using a silicon– organic hybrid device显示文摘Energy-efficient electro-optic modulators are at the heart of short-reach optical interconnects,and silicon photonics is considered the leading technology for realizing such devices.However,the performance of all-silicon devices is limited by intrinsic material properties.In particular,the absence of linear electro-optic effects in silicon renders the integration of energy-efficient photonic–electronic interfaces challenging.Silicon–organic hybrid(SOH)integration can overcome these limitations by combining nanophotonic silicon waveguides with organic cladding materials,thereby offering the prospect of designing optical properties by molecular engineering.In this paper,we demonstrate an SOH Mach–Zehnder modulator with unprecedented efficiency:the 1-mm-long device consumes only 0.7 fJ bit^(-1) to generate a 12.5 Gbit s^(-1) data stream with a bit-error ratio below the threshold for hard-decision forward-error correction.This power consumption represents the lowest value demonstrated for a non-resonant Mach–Zehnder modulator in any material system.It is enabled by a novel class of organic electro-optic materials that are designed for high chromophore density and enhanced molecular orientation.The device features an electro-optic coefficient of r33<180 pm V^(-1) and can be operated at data rates of up to 40 Gbit s^(-1). | Sebastian Koeber Robert Palmer Matthias Lauermann Wolfgang Heni Delwin L Elder Dietmar Korn Markus Woessner Luca Alloatti Swen Koenig Philipp C Schindler Hui Yu Wim Bogaerts Larry R Dalton Wolfgang Freude Juerg Leuthold Christian Koos | 2015 | Light(Science & Applications)2015，4，1： | 4 |
| 4 | Solution conformation of cobrotoxin: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study显示文摘 | Yu C Bhaskaran R Chuang LC | 1993 | Biochem1993，32，： | 2 |
| 5 | Uniform Metal Nanotube Arrays by Multistep Template Replication and Electrodeposition显示文摘 | Yu Y X Wang R M | 2004 | Adv Mater2004，16，17： | 1 |
| 6 | The existence of Intera-Granular ferrite plates and nucleating inclusions in the heat affected zone of X60 pipe steel显示文摘 | Guo C J Yu R Z Zhu Q G | 1997 | J Mater Sci1997，，： | 1 |
| 7 | Replication ofavian and seasonal influenza viruses in human bronchus andlung显示文摘 | Chan R W Y Yuen K M Yu W C L | 2011 | Influenza Other Resp Viruses2011，5，： | 1 |
| 8 | Effects of a purified sap-onin miture from alfalfa on plasma lipid metabolism in hyperlipidemic mice 显示文摘 | Yu C H Xie G He R R | 2011 | Journal of Health Science2011，57，5： | 1 |
| 9 | Integrating Case-based and Fuzzy Reasoning to Qualitatively Predict Risk in an Environmental Impact Assessment Review显示文摘 | Liu K F R Yu C W | 2009 | En- vironmental Modelling & Software2009，24，10： | 1 |
| 10 | An adaptive Kalman filter for dynamic harmonic state estimation and harmonic injection tracking显示文摘 | Yu K K C Watson N R Arrillaga J | 2005 | IEEE Transactions on Power Delivery2005，20，2： | 1 |
| 11 | Viral genome phylogeny based on Lempel-Ziv complexity and Haus- dorff distance 显示文摘 | YU C LUCY HE R YAU S S-T | 2014 | Journal of theoretical biology2014，348，： | 1 |
| 12 | Expression pattern genomic struc- ture, and promoter analysis of the gene encoding stilbene synthase from Chinese wild Vitis pseudoreticulata显示文摘 | XU W R YU Y H ZHOU Q DING J H DAI L M XIE X Q XU Y ZHANG C H WANG Y J | 2011 | Journal of Experimen- tal Botany2011，62，8： | 1 |
| 13 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 14 | Developmental, cytological and transcriptional analysis of autotetraploid Arabidopsis 显示文摘 | Li X D Yu E R Fan C C | 2012 | Planta2012，236，2： | 1 |
| 15 | Influence of gene polymorphisms of the rennin-angiotensin system on clinical outcome in heart failure among the chinese显示文摘 | SANDERSONJ E YU C M YOUNG R P | 1999 | American Heart J1999，137，： | 1 |
| 16 | Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra显示文摘 | Yu L R Zhu Z Y Chan K C | 2007 | J Proteome Res2007，6，： | 1 |
| 17 | Viability of Lactic acid bacteria and Bifidobacteria in fermented soymilk after drying, subsequent rehydration and storage 显示文摘 | Wang Y C Yu R C Chou C C | 2004 | International Journal of Food Microbiology2004，93，2： | 1 |
| 18 | Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1 显示文摘 | Zhao C Yu DH Shen R | 1999 | J Biol Chem1999，274，19： | 1 |
| 19 | A novel density-tunable nanoeomposites of CdTe quantum dots linked to dendrimer-tethered multiwall carbon nanotubes显示文摘 | Zeng Y L Tang C R Wang H W Jiang J H Tian M N Shen G L Yu R Q | 2008 | Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy2008，70，5： | 1 |
| 20 | Why the Western Pacific Subtropical High has Extended Westward since the Late 1970s显示文摘 | ZHOU T J YU R C ZHANG J | 1970 | Journal of Climate1970，，： | 1 |
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